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The map label for this gene is comL [H]

Identifier: 34497648

GI number: 34497648

Start: 2365119

End: 2365913

Strand: Direct

Name: comL [H]

Synonym: CV_2193

Alternate gene names: 34497648

Gene position: 2365119-2365913 (Clockwise)

Preceding gene: 34497640

Following gene: 34497650

Centisome position: 49.78

GC content: 61.89

Gene sequence:

>795_bases
ATGAAAAGATACGTTGTTGCGGCTATGTTGGTGATGGTGGGTCTTGCCGGGTGTGCGACCACGGAAACCTACGACGAGAC
GCGCGGCTGGACCGTGGAGAAGCTGTATTCGGAAGCTCACGACGAGTTGAACAGCGGCAATTATACCCGCGCAGTCAAGC
TGTATGAAACGCTGGAAGCGCGTTTCCCCTACGGCCGCTACGCGCAGCAGGCGCAGATGGATCTGGCCTACACCCATTAC
AAGGATGGCGAACCCGAACTGGCCATCGCCTCCGCCGACCGTTTCATCAAGCTGCATCCCACGCATCCGAACCTCGACTA
CATCTATTATCTGAAGGGTTTGGTGTATTACAACGACGATTCTGGCTTGCTGGCCAAATGGGCCGGCCAGGACATGAGCG
AGCGCGATCCGCGCGCCGCGCGCGAGGCGTTCGCCGCCTTCCGCGAGCTGACCACCCGCTTCCCCAGCAGCAGCTACGCG
CCGGACGCCAAGGCCAAGATGATCCGCCTGGTGGACGCCCTGGGCGGCAACGAAATGCACGTGGCGCGCTACTACATGAA
GCGCGGCGCCTATCTGGCCGCCGCCAATCGCGCGCAGGGCGTGGTCAAGGATTACGCCAACACCAAGTATCCGGAAGAGG
CGCTGGCCATCATGGTGGCCGCCTACGACAAGCTGCAGTTGCCGCAGCTGCGCGACGACGCGCGCCGCGTGCTGGCGCTC
AATTACCCGCAGAGCCAGTACCTGGGCAAGTCGTGGACGGTGGAGGAGATGCCGTGGTGGAAGCTGTGGAAATAA

Upstream 100 bases:

>100_bases
TTCGCCGCACAGCGAGAGCGGAATTTCGAGATGTTGCGTAGTGGATACCTCGTTTTCCGAGATGTCGCTATAATCGTCCG
GGTCAATGTAAGGATCAGTC

Downstream 100 bases:

>100_bases
GCTTTCCGGCAAGCTGAAACCAAGCAGCCCGTCGAGTCATCGGCGGGCTGTTTTGTTGTTTTTTGGGTCAAAGGCCGGCG
ATGCGTTCCCGGCAGGCTTG

Product: competence lipoprotein ComL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKRYVVAAMLVMVGLAGCATTETYDETRGWTVEKLYSEAHDELNSGNYTRAVKLYETLEARFPYGRYAQQAQMDLAYTHY
KDGEPELAIASADRFIKLHPTHPNLDYIYYLKGLVYYNDDSGLLAKWAGQDMSERDPRAAREAFAAFRELTTRFPSSSYA
PDAKAKMIRLVDALGGNEMHVARYYMKRGAYLAAANRAQGVVKDYANTKYPEEALAIMVAAYDKLQLPQLRDDARRVLAL
NYPQSQYLGKSWTVEEMPWWKLWK

Sequences:

>Translated_264_residues
MKRYVVAAMLVMVGLAGCATTETYDETRGWTVEKLYSEAHDELNSGNYTRAVKLYETLEARFPYGRYAQQAQMDLAYTHY
KDGEPELAIASADRFIKLHPTHPNLDYIYYLKGLVYYNDDSGLLAKWAGQDMSERDPRAAREAFAAFRELTTRFPSSSYA
PDAKAKMIRLVDALGGNEMHVARYYMKRGAYLAAANRAQGVVKDYANTKYPEEALAIMVAAYDKLQLPQLRDDARRVLAL
NYPQSQYLGKSWTVEEMPWWKLWK
>Mature_264_residues
MKRYVVAAMLVMVGLAGCATTETYDETRGWTVEKLYSEAHDELNSGNYTRAVKLYETLEARFPYGRYAQQAQMDLAYTHY
KDGEPELAIASADRFIKLHPTHPNLDYIYYLKGLVYYNDDSGLLAKWAGQDMSERDPRAAREAFAAFRELTTRFPSSSYA
PDAKAKMIRLVDALGGNEMHVARYYMKRGAYLAAANRAQGVVKDYANTKYPEEALAIMVAAYDKLQLPQLRDDARRVLAL
NYPQSQYLGKSWTVEEMPWWKLWK

Specific function: Required for efficient transformation of Neisseria gonorrhoeae by species-related DNA [H]

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=239, Percent_Identity=38.4937238493724, Blast_Score=183, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689
- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30268; Mature: 30268

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYVVAAMLVMVGLAGCATTETYDETRGWTVEKLYSEAHDELNSGNYTRAVKLYETLEA
CCHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RFPYGRYAQQAQMDLAYTHYKDGEPELAIASADRFIKLHPTHPNLDYIYYLKGLVYYNDD
CCCCCHHHHHHHHHHHEEECCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEEEEEECC
SGLLAKWAGQDMSERDPRAAREAFAAFRELTTRFPSSSYAPDAKAKMIRLVDALGGNEMH
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHH
VARYYMKRGAYLAAANRAQGVVKDYANTKYPEEALAIMVAAYDKLQLPQLRDDARRVLAL
HHHHHHHCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCEEEEE
NYPQSQYLGKSWTVEEMPWWKLWK
CCCHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRYVVAAMLVMVGLAGCATTETYDETRGWTVEKLYSEAHDELNSGNYTRAVKLYETLEA
CCHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RFPYGRYAQQAQMDLAYTHYKDGEPELAIASADRFIKLHPTHPNLDYIYYLKGLVYYNDD
CCCCCHHHHHHHHHHHEEECCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEEEEEECC
SGLLAKWAGQDMSERDPRAAREAFAAFRELTTRFPSSSYAPDAKAKMIRLVDALGGNEMH
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHH
VARYYMKRGAYLAAANRAQGVVKDYANTKYPEEALAIMVAAYDKLQLPQLRDDARRVLAL
HHHHHHHCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCEEEEE
NYPQSQYLGKSWTVEEMPWWKLWK
CCCHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8830266 [H]