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The map label for this gene is dapA [H]

Identifier: 34497503

GI number: 34497503

Start: 2235456

End: 2236358

Strand: Reverse

Name: dapA [H]

Synonym: CV_2048

Alternate gene names: 34497503

Gene position: 2236358-2235456 (Counterclockwise)

Preceding gene: 34497504

Following gene: 34497501

Centisome position: 47.07

GC content: 73.09

Gene sequence:

>903_bases
ATGGCAAAACACTGGGGCAAGGTGCTGACCGCGATGGTGACGCCGTTCGACGGCGACGGCCGGCTCAACCTCGACGCGGC
GCGCGCGCTGGCGCGCCACCTGGCGGATAACGGCAGCGACGCGCTGGTGCTGGCCGCCACCACCGGCGAGGCGCCCACGC
TGGACGACGCCGAGCGCTTCGACCTGATCCGCGCGGTCAGCGACGCAGTGACCATTCCGGTGCTGGCAGGCACCGGCAGC
AACGACACCCGCCACGCGCTGGCGATGACCGCCCGGGCCGAGGCGGCCGGCGCCGCCGGCGTGTTCCTGGTCTCTCCGTA
CTACAACCGCCCGCCGCAGGCCGGCATCGAGGCCCACTTCCGCGCGCTGGCCGCCGCCACCCGGCTGCCGGTGATGATCT
ACGACGTCCCCGGCCGCACCGGCCGCCGCATCGCCCACGACGTGCTGCTGCGGCTGTTCCGCGAGGTGGACAATATCGTC
GCCTTCAAGGACGCCACCTGCGACCCCGCCGCCGCCGCGCGGCTGGTGGCCGAGGCCGGAGAGCATTTCGAGCTCTACTC
CGGCGACGACGCGCTGACCCTGCCCCTGCTGGCGGTCGGCGCGGTGGGCGTGGTGGGCACCTCCACCCACTGGACCGGCC
CGGAGTTCGCCGAGATGATCGCCGCCTTCGAGCGGGGCGACGCGGGCCGCGCCCGCGAGATCAACGCCGCGTTGATGCCG
TCCTATGCCTATTCCAACACCGACGATTCGGTGTACTCGATGTCGGTGAAGGCGATGCTGCGCGCCCTGGGCCTGGCTGT
CGGCGAATGCAGGCTGCCGCTGCCGGCGACGCCTGCCGGCGTCGAGGCGCGCGCCGCGGAAATATGGCGCGAGCTGGAGG
CCTGGCGCGCCGCCCAGCGCTGA

Upstream 100 bases:

>100_bases
AGCTGGATCCCAAGCTTTGGTAAGCGCCGCGGGTTCCCGCGCCCAGGGGCGAGGAGTATCATCCCTGCCTGTCTTCACGC
AAAAATAAAAAGGGGCTGAC

Downstream 100 bases:

>100_bases
GCGGCCGCCGGCAATAAAAAAGGAGACCCTTGGGTCTCCTTTTTCGTGACTGGCGCGCCGCGCGGCGGGAGTCAGTCGCG
GAAGTTGTTGAACTGCAGCG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAKHWGKVLTAMVTPFDGDGRLNLDAARALARHLADNGSDALVLAATTGEAPTLDDAERFDLIRAVSDAVTIPVLAGTGS
NDTRHALAMTARAEAAGAAGVFLVSPYYNRPPQAGIEAHFRALAAATRLPVMIYDVPGRTGRRIAHDVLLRLFREVDNIV
AFKDATCDPAAAARLVAEAGEHFELYSGDDALTLPLLAVGAVGVVGTSTHWTGPEFAEMIAAFERGDAGRAREINAALMP
SYAYSNTDDSVYSMSVKAMLRALGLAVGECRLPLPATPAGVEARAAEIWRELEAWRAAQR

Sequences:

>Translated_300_residues
MAKHWGKVLTAMVTPFDGDGRLNLDAARALARHLADNGSDALVLAATTGEAPTLDDAERFDLIRAVSDAVTIPVLAGTGS
NDTRHALAMTARAEAAGAAGVFLVSPYYNRPPQAGIEAHFRALAAATRLPVMIYDVPGRTGRRIAHDVLLRLFREVDNIV
AFKDATCDPAAAARLVAEAGEHFELYSGDDALTLPLLAVGAVGVVGTSTHWTGPEFAEMIAAFERGDAGRAREINAALMP
SYAYSNTDDSVYSMSVKAMLRALGLAVGECRLPLPATPAGVEARAAEIWRELEAWRAAQR
>Mature_299_residues
AKHWGKVLTAMVTPFDGDGRLNLDAARALARHLADNGSDALVLAATTGEAPTLDDAERFDLIRAVSDAVTIPVLAGTGSN
DTRHALAMTARAEAAGAAGVFLVSPYYNRPPQAGIEAHFRALAAATRLPVMIYDVPGRTGRRIAHDVLLRLFREVDNIVA
FKDATCDPAAAARLVAEAGEHFELYSGDDALTLPLLAVGAVGVVGTSTHWTGPEFAEMIAAFERGDAGRAREINAALMPS
YAYSNTDDSVYSMSVKAMLRALGLAVGECRLPLPATPAGVEARAAEIWRELEAWRAAQR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=293, Percent_Identity=24.5733788395904, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31543060, Length=278, Percent_Identity=24.8201438848921, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1788823, Length=283, Percent_Identity=35.3356890459364, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082415, Length=292, Percent_Identity=29.1095890410959, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786463, Length=277, Percent_Identity=28.158844765343, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789620, Length=238, Percent_Identity=25.6302521008403, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31820; Mature: 31689

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHWGKVLTAMVTPFDGDGRLNLDAARALARHLADNGSDALVLAATTGEAPTLDDAERF
CCCHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHH
DLIRAVSDAVTIPVLAGTGSNDTRHALAMTARAEAAGAAGVFLVSPYYNRPPQAGIEAHF
HHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHH
RALAAATRLPVMIYDVPGRTGRRIAHDVLLRLFREVDNIVAFKDATCDPAAAARLVAEAG
HHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCC
EHFELYSGDDALTLPLLAVGAVGVVGTSTHWTGPEFAEMIAAFERGDAGRAREINAALMP
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCHHHCC
SYAYSNTDDSVYSMSVKAMLRALGLAVGECRLPLPATPAGVEARAAEIWRELEAWRAAQR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKHWGKVLTAMVTPFDGDGRLNLDAARALARHLADNGSDALVLAATTGEAPTLDDAERF
CCHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHH
DLIRAVSDAVTIPVLAGTGSNDTRHALAMTARAEAAGAAGVFLVSPYYNRPPQAGIEAHF
HHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHH
RALAAATRLPVMIYDVPGRTGRRIAHDVLLRLFREVDNIVAFKDATCDPAAAARLVAEAG
HHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCC
EHFELYSGDDALTLPLLAVGAVGVVGTSTHWTGPEFAEMIAAFERGDAGRAREINAALMP
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCHHHCC
SYAYSNTDDSVYSMSVKAMLRALGLAVGECRLPLPATPAGVEARAAEIWRELEAWRAAQR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA