Click here to switch to the map view.

The map label for this gene is yhcS [C]

Identifier: 34497470

GI number: 34497470

Start: 2196696

End: 2197730

Strand: Reverse

Name: yhcS [C]

Synonym: CV_2015

Alternate gene names: 34497470

Gene position: 2197730-2196696 (Counterclockwise)

Preceding gene: 34497472

Following gene: 34497469

Centisome position: 46.26

GC content: 67.25

Gene sequence:

>1035_bases
ATGCAGGACCTGAACGATCTCCTGTATTTCGCCAAAGTCGTCGAACACGGCGGCTTCATGGCTGCCGGACGGGTGCTGGG
CATTCCCAAATCCAAACTGTCCCGCCGCGTGGCCGAGCTGGAAACCAGGCTGGGCGTGCGCCTGCTGCAGCGAACCACGC
GCCGGCTGTCGCTGACCGAGATCGGCGGCCAGTACTACCAGCACTGCCAGGCCATGCTGGCTGAAGCCGAGGCCGCCGAC
GAAGCGGTGCTGCACAGCAGCGCCGAGCCGCGCGGCCTGATCCGCGTCAGCTGCCCGGAACTGCTGTGCAAGACCATGCT
CAGCCTGGTCCTGCCGCGGTTTCTCGCCCTTCACCCGCAGGTGCGGGTCACGCTGGACTCCACCAACCGCCGGGTTGATC
TGGTGGAGGAAGGCGTGGACGTGGCGATCCGGGTCCGCAACGTGATCGAAGACAGCGCCAGCCTGGTGGTGCGCCGGCTG
GGCAGAAGCCGGGTGATCCTGGTGGCCAGCCCCGCCTTCCTCGAAATCCATGGCGAGCCGAAGACGCCGGAGCGGCTGGC
CGCGCTGCCGGCGCTGACCATGAGCCGGCCGGACGGCCGCGGCCAATGGGTGTTGCTGGACAATGTCGGCCAGAGCTACA
CCATCCACCTGGACGCGCCGCGGCTGATGACCGACGATATGATCGTGCTGCTGGAAGCCGCCGCCGCCGGCGTCGGGGGT
CACCGCGCTGCCGGCCAACGTCTGCCACCAGGCGCTCGCGGATGGACGGCTGCGGCACATCCTGCCGCAGTACGACTTCC
CCTGGGGCATCCTGCATGCGGCCTTCCCCACCCGGCGCGGCTTGTCGCCGGCGGTGCGCGCCTTCATCGATTTCGTCTCG
GAGCAGTTGATCAGCGAAGAGATGGCCGGCGACTGGCAGCGCGCCGATATCCGCCCGGCATGACAATTGCTTCAGTCCCG
CTTTTCCATACAGGATTGCCGAAGACATGTTCACGCTGCGCCCGCTGGCCGAAACCGACTCGATCGAACAACTGA

Upstream 100 bases:

>100_bases
TTCCTTCGGGGTTCGATTGCGATGAGTGGATGATAGATATCCGCAACAATCTGGACTAGTCTGCTAAAATCGAAAACATT
GTTCTACCAGTGAGACAATC

Downstream 100 bases:

>100_bases
CCGCGCTGCTGCACCGCGCCTACGCCCAGCTGGCGGCGATGGGCCTGCGCTACACCGCGGTGGACCAGAGCGCGGCCGTC
ACCCGCCGCCGCATCGCCGG

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MQDLNDLLYFAKVVEHGGFMAAGRVLGIPKSKLSRRVAELETRLGVRLLQRTTRRLSLTEIGGQYYQHCQAMLAEAEAAD
EAVLHSSAEPRGLIRVSCPELLCKTMLSLVLPRFLALHPQVRVTLDSTNRRVDLVEEGVDVAIRVRNVIEDSASLVVRRL
GRSRVILVASPAFLEIHGEPKTPERLAALPALTMSRPDGRGQWVLLDNVGQSYTIHLDAPRLMTDDMIVLLEAAAAGVGG
HRAAGQRLPPGARGWTAAAHPAAVRLPLGHPACGLPHPARLVAGGARLHRFRLGAVDQRRDGRRLAARRYPPGMTIASVP
LFHTGLPKTCSRCARWPKPTRSNN

Sequences:

>Translated_344_residues
MQDLNDLLYFAKVVEHGGFMAAGRVLGIPKSKLSRRVAELETRLGVRLLQRTTRRLSLTEIGGQYYQHCQAMLAEAEAAD
EAVLHSSAEPRGLIRVSCPELLCKTMLSLVLPRFLALHPQVRVTLDSTNRRVDLVEEGVDVAIRVRNVIEDSASLVVRRL
GRSRVILVASPAFLEIHGEPKTPERLAALPALTMSRPDGRGQWVLLDNVGQSYTIHLDAPRLMTDDMIVLLEAAAAGVGG
HRAAGQRLPPGARGWTAAAHPAAVRLPLGHPACGLPHPARLVAGGARLHRFRLGAVDQRRDGRRLAARRYPPGMTIASVP
LFHTGLPKTCSRCARWPKPTRSNN
>Mature_344_residues
MQDLNDLLYFAKVVEHGGFMAAGRVLGIPKSKLSRRVAELETRLGVRLLQRTTRRLSLTEIGGQYYQHCQAMLAEAEAAD
EAVLHSSAEPRGLIRVSCPELLCKTMLSLVLPRFLALHPQVRVTLDSTNRRVDLVEEGVDVAIRVRNVIEDSASLVVRRL
GRSRVILVASPAFLEIHGEPKTPERLAALPALTMSRPDGRGQWVLLDNVGQSYTIHLDAPRLMTDDMIVLLEAAAAGVGG
HRAAGQRLPPGARGWTAAAHPAAVRLPLGHPACGLPHPARLVAGGARLHRFRLGAVDQRRDGRRLAARRYPPGMTIASVP
LFHTGLPKTCSRCARWPKPTRSNN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=240, Percent_Identity=34.1666666666667, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786401, Length=207, Percent_Identity=35.2657004830918, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87081978, Length=208, Percent_Identity=35.0961538461538, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI145693193, Length=188, Percent_Identity=34.0425531914894, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1789440, Length=202, Percent_Identity=27.2277227722772, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787128, Length=239, Percent_Identity=25.9414225941423, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787589, Length=241, Percent_Identity=26.9709543568465, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082132, Length=177, Percent_Identity=29.9435028248588, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=114, Percent_Identity=30.7017543859649, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37587; Mature: 37587

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLNDLLYFAKVVEHGGFMAAGRVLGIPKSKLSRRVAELETRLGVRLLQRTTRRLSLTE
CCCHHHHHHHHHHHHCCCCEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGQYYQHCQAMLAEAEAADEAVLHSSAEPRGLIRVSCPELLCKTMLSLVLPRFLALHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCC
VRVTLDSTNRRVDLVEEGVDVAIRVRNVIEDSASLVVRRLGRSRVILVASPAFLEIHGEP
EEEEECCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCC
KTPERLAALPALTMSRPDGRGQWVLLDNVGQSYTIHLDAPRLMTDDMIVLLEAAAAGVGG
CCHHHHHHCCHHHCCCCCCCCCEEEEECCCCEEEEEECCCCHHHCHHHHHHHHHHCCCCC
HRAAGQRLPPGARGWTAAAHPAAVRLPLGHPACGLPHPARLVAGGARLHRFRLGAVDQRR
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHCCHHHHEEECCCCCCCC
DGRRLAARRYPPGMTIASVPLFHTGLPKTCSRCARWPKPTRSNN
CCHHHHHHCCCCCCEEEECCHHHCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQDLNDLLYFAKVVEHGGFMAAGRVLGIPKSKLSRRVAELETRLGVRLLQRTTRRLSLTE
CCCHHHHHHHHHHHHCCCCEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGQYYQHCQAMLAEAEAADEAVLHSSAEPRGLIRVSCPELLCKTMLSLVLPRFLALHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCC
VRVTLDSTNRRVDLVEEGVDVAIRVRNVIEDSASLVVRRLGRSRVILVASPAFLEIHGEP
EEEEECCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCC
KTPERLAALPALTMSRPDGRGQWVLLDNVGQSYTIHLDAPRLMTDDMIVLLEAAAAGVGG
CCHHHHHHCCHHHCCCCCCCCCEEEEECCCCEEEEEECCCCHHHCHHHHHHHHHHCCCCC
HRAAGQRLPPGARGWTAAAHPAAVRLPLGHPACGLPHPARLVAGGARLHRFRLGAVDQRR
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHCCHHHHEEECCCCCCCC
DGRRLAARRYPPGMTIASVPLFHTGLPKTCSRCARWPKPTRSNN
CCHHHHHHCCCCCCEEEECCHHHCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]