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The map label for this gene is hslO

Identifier: 34497455

GI number: 34497455

Start: 2179261

End: 2180145

Strand: Direct

Name: hslO

Synonym: CV_2000

Alternate gene names: 34497455

Gene position: 2179261-2180145 (Clockwise)

Preceding gene: 34497454

Following gene: 34497456

Centisome position: 45.87

GC content: 64.97

Gene sequence:

>885_bases
ATGAATATGAACCATCACGACAAACTGCAACGATTCCTGTTCGACGGCGCGCCGGTGCGCGGCGCGCTGGTGCGGCTGGA
CGGCGCCTGGCAACAGGTGCTGGCGCGGCGCGCTTATCCCCAGGCGCTGAAAACCGTGCTGGGCGAAATGATGGCGGCCT
CGGTGCTGATGGCGGCCAACCTTAAATTCGATGGCTCGCTGATCCTGCAGATCCACGGCACCGGCGCGCTGAAACTGGCG
GTGGTGGAGTGCAACAACGACCGCACCGTGCGCGCCACCGCCAAGTGGGACGGCGATCTGGACGGCAAGCCGCTGAAAGC
GCTGCTGGGCGAGGGCGGCAAATTCGTGCTGACGCTGGAGCCGCGCCTGGACAAGAATCAGACCTGGCAAGGCATCGTGG
CGCTGGAAGGCGACTCCGTCGGCCAGATGCTGGAAAACTACATGCTGCGCTCCGAACAGCTGGATACGGCGCTGGTGCTG
GCCAGCGGCGACGAGGCCGCCGCCGGCATGCTGCTGCAGCGCCTGCCGGAAGGCCATGGCGAGGCCGAAGGCTGGGACCG
CGTCCAGATGCTGGGCCGCACGCTGAAGGCTGAGGAGTTGCTGGGCCTGGGCGCCGAGGACATCCTGCACCGCCTGTTCC
ACGAAGAGCAGGTGCGCGTGTTCGAGCAGGAAACCGTCAGCTTCAACTGCAACTGCTCGCGCGAACGCGTCAGCAATATG
CTGACCATGCTGGGCGGCCAGGAAGTGGGCGATGTGCTGCTGGAGCAGGGCAGCGTGGAGATCGTCTGCGACTACTGCAA
CCAGCGCTATGTGTTCGACGAGGAAGACGCCAATCAGTTGTTCGATTACGACGTAGTGGCGGCGGCGCGCGAAGCGCGGC
ATTGA

Upstream 100 bases:

>100_bases
CCGAGATCGGCGTGCGCGCCGGCTGCGAATTCGACGTCAGCTCCTCGCTGCCGATGACCGTATATACCGTTGAAGTGGCC
GCCGGCGCGGCCAAGGAAGC

Downstream 100 bases:

>100_bases
GGTTTGCAATTTCCATTCAAAAAAGCCGCTTATGCGGCTTTTTTTGCGTTTTCTTAAGCTGAAACAGGGCGTGAAAATTA
ACTGCCTTGTTTTGTTGTTT

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNMNHHDKLQRFLFDGAPVRGALVRLDGAWQQVLARRAYPQALKTVLGEMMAASVLMAANLKFDGSLILQIHGTGALKLA
VVECNNDRTVRATAKWDGDLDGKPLKALLGEGGKFVLTLEPRLDKNQTWQGIVALEGDSVGQMLENYMLRSEQLDTALVL
ASGDEAAAGMLLQRLPEGHGEAEGWDRVQMLGRTLKAEELLGLGAEDILHRLFHEEQVRVFEQETVSFNCNCSRERVSNM
LTMLGGQEVGDVLLEQGSVEIVCDYCNQRYVFDEEDANQLFDYDVVAAAREARH

Sequences:

>Translated_294_residues
MNMNHHDKLQRFLFDGAPVRGALVRLDGAWQQVLARRAYPQALKTVLGEMMAASVLMAANLKFDGSLILQIHGTGALKLA
VVECNNDRTVRATAKWDGDLDGKPLKALLGEGGKFVLTLEPRLDKNQTWQGIVALEGDSVGQMLENYMLRSEQLDTALVL
ASGDEAAAGMLLQRLPEGHGEAEGWDRVQMLGRTLKAEELLGLGAEDILHRLFHEEQVRVFEQETVSFNCNCSRERVSNM
LTMLGGQEVGDVLLEQGSVEIVCDYCNQRYVFDEEDANQLFDYDVVAAAREARH
>Mature_294_residues
MNMNHHDKLQRFLFDGAPVRGALVRLDGAWQQVLARRAYPQALKTVLGEMMAASVLMAANLKFDGSLILQIHGTGALKLA
VVECNNDRTVRATAKWDGDLDGKPLKALLGEGGKFVLTLEPRLDKNQTWQGIVALEGDSVGQMLENYMLRSEQLDTALVL
ASGDEAAAGMLLQRLPEGHGEAEGWDRVQMLGRTLKAEELLGLGAEDILHRLFHEEQVRVFEQETVSFNCNCSRERVSNM
LTMLGGQEVGDVLLEQGSVEIVCDYCNQRYVFDEEDANQLFDYDVVAAAREARH

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=283, Percent_Identity=40.9893992932862, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_CHRVO (Q7NWI9)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901670.1
- ProteinModelPortal:   Q7NWI9
- SMR:   Q7NWI9
- GeneID:   2547569
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2000
- NMPDR:   fig|243365.1.peg.2000
- HOGENOM:   HBG296531
- OMA:   AMTIDQG
- PhylomeDB:   Q7NWI9
- ProtClustDB:   PRK00114
- BioCyc:   CVIO243365:CV_2000-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32616; Mature: 32616

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMNHHDKLQRFLFDGAPVRGALVRLDGAWQQVLARRAYPQALKTVLGEMMAASVLMAAN
CCCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
LKFDGSLILQIHGTGALKLAVVECNNDRTVRATAKWDGDLDGKPLKALLGEGGKFVLTLE
CEECCEEEEEEECCCEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHCCCCEEEEEEC
PRLDKNQTWQGIVALEGDSVGQMLENYMLRSEQLDTALVLASGDEAAAGMLLQRLPEGHG
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCC
EAEGWDRVQMLGRTLKAEELLGLGAEDILHRLFHEEQVRVFEQETVSFNCNCSRERVSNM
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
LTMLGGQEVGDVLLEQGSVEIVCDYCNQRYVFDEEDANQLFDYDVVAAAREARH
HHHHCCHHHHHHHHHCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMNHHDKLQRFLFDGAPVRGALVRLDGAWQQVLARRAYPQALKTVLGEMMAASVLMAAN
CCCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
LKFDGSLILQIHGTGALKLAVVECNNDRTVRATAKWDGDLDGKPLKALLGEGGKFVLTLE
CEECCEEEEEEECCCEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHCCCCEEEEEEC
PRLDKNQTWQGIVALEGDSVGQMLENYMLRSEQLDTALVLASGDEAAAGMLLQRLPEGHG
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCC
EAEGWDRVQMLGRTLKAEELLGLGAEDILHRLFHEEQVRVFEQETVSFNCNCSRERVSNM
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
LTMLGGQEVGDVLLEQGSVEIVCDYCNQRYVFDEEDANQLFDYDVVAAAREARH
HHHHCCHHHHHHHHHCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782