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The map label for this gene is cirA [H]

Identifier: 34497425

GI number: 34497425

Start: 2142963

End: 2145527

Strand: Direct

Name: cirA [H]

Synonym: CV_1970

Alternate gene names: 34497425

Gene position: 2142963-2145527 (Clockwise)

Preceding gene: 34497424

Following gene: 34497426

Centisome position: 45.1

GC content: 56.53

Gene sequence:

>2565_bases
ATGGGATTTGGAGAAATGATGAACTACAAGAGAAAAACGCTTGCGATAGCGCTGTCGCTGATCGGCAGTGTTGGCTACAT
GCCCTTGGCGCATGCGGACTCGGATAGCTCCGGCACGCTGGATCGTGTGGAAGTGACCGGATCGAACATCAAACGTTCGA
TCAGCAAAGAAACCGCAGTTCCGATGACCATCATCAAAACGGATGATCTGGTCAAGCAGGGCCTGACCTCCGTCGAGCAA
GTGGTCAACAGCCTGGCCGCCAACCAATCCAGCCAGGGCGCCAATGCGGCGGTCGGCGCATCTACCGGCGGCGCCGCGTA
TGCCAGCCTGCGTGGCCTGGGCCACCAGTACACCTTGATTCTGCTCGATGGCCGACGCATCGTGAATCAGCCGATGGACG
GCACGTCGGTAGATTTGAATGCCATTCCGCTTTCCGTGATTGATCGCGTCGAGGTGGTGCGTGATGGAGCTTCCGCGATC
TACGGTACCGATGCGATCGGCGGCGTAATCAACTTCATCACTAAAAAGACCATGACGGGCCTGAATATCGGTGGCGAATT
TGTGTCCCCGCAGCGATCCGGAGGCAAGGAGAAAAGCGTCAACATCTCCTATGGCTATGGCGATCTCGGCAAAGATGGAT
TCAACATCTATGGCGCTTACGATTACCACAAGACCGAAAAGATCATGGCCACCGACCGTGATTTTGCTTCGACGATCACA
AGCAGCACCAAGCGCAGCGTCAACAGCTTCCCGGCCAATTACCTGAATTCCAAGGGCGATCTGGTGGCCGCAAACCCGGC
TTGTAAACCACCGTACTCGATTCCGGATGGCAGCGGCGCCTGCTCCGAGCTGTATTCCCTTTTCCCGTCCATTCAGCCGG
AAATCGAGCAGCAAACCGCCGTGCTGAAGGGGACGACTCGTCTGGGCGATCATGAGTTGTCGCTGCAGTACATGATCACC
AAGACCAAAAACACGACCTGGGTGGCACCTACGCCTTTTTCCGGTGATGTCACATCGCCCACCGCGCCGGGGGAAAATCC
TGCCAATGGCCCATTCCCGCTCTACGGGCGCTCGGTGCCTGCGGGGGATCGCGTGGACAGCAGCACGGCGACGACCCAGC
GTTTGCAGTTTAATGCGGAAGGCTTGATCGCCGGCTGGGATTATCGCGCGGGCCTTGGCCATTCTGAGAGCAAGGTGACG
CATGATGTAGTCAGCGGCTACCTGAGCCAGAGCAAGCTGCAAAATGCTTTGAATAATGGTTTCAACCCGGATACCGAAGA
TCCGGCCGCATGGGCACCATACGCATCCACCGGGCAAATTGAGCAAGCCAAATCCAAACTTGATCAGGCTGATTTCAAGG
TGAGCAAGGAAGTGTACCAACTGCCGGCGGGTATGCTTGCGGTGGCGTTGGGCGTAGAGACCCGGCATGAGACTATTGAG
CATACTTATAACCATGCAGTGGCATCGGATACGCTCAGCACCGGCTTGACTAAGACGACGGATGGTTCCGGCAGTCGCAA
TGCGCAAGCTTTGTACGCCGAGATGGACATTCCCGTGATCAAGCACCTGGATGCCAACCTCGCTGTCCGTTACGACCATT
ACAGCGACTCCGGCAGCTCGGTCAATCCGAAGGTATCCCTGAAGTACCAGCCCATCCCGCAGCTGCTGTTGCGTACTTCG
GCCAGCACGGGTTTCCGCGCGCCGTCGCTGTACGACATCAACCAGCCTAACCAGCAGCAACTGACTGCCAAGAACTACAC
CGACCCGGTATTGTGCCCTGGCGGCGTCGCGCAGCCTGGCGCGGGCTCTAATTCTTGCGTCAAGACTCAGCAGAACCTGT
TTGTCGGCGGCAACAAGTCGTTGAATCCGGAAAAATCGTCTTCCCTGTCGTTTGGCATGGTGCTTGAGCCGGTCAAGGAT
CTGACGACCAGCGTCGATTTCTGGTGGACGAATATCCAGAACACCATCGGCTCCTTGAATGAAGCGACGATTTTTGGCAA
TCCGAGCAAGTATGGCAATCTGTTCGTGCGAGATGGCAGCAACAACCTGCTGTACGTGATGGATGCCACCCAGAACCTGG
GGAATACCAGCGCGGCCGGGGTTGATCTTGGCTTCTCGTACCGCTTCCCGCGCACGGCCATTGGTACCTTCTCCGTCAAT
CTGGATGGAACCTATATCAGCAAACATATGTTCCAGTACGAGAAAGGCGGCGATTACCATAGCGACCTGGGCGCATACGT
GAATGGCGGCCCGACTTTCCGTTGGCAGCACAATCTTTCCTTGAACTGGTCGGAAGGCGCATGGAGCGGGATCCTGGCTC
AGGACTACAAGTCCGGTTATACGGACGATGTGGCAACGCACATGGTCAAGCCTTATTCCACCTGGAACCTGTCGGGCAGC
TATGCCTGGGACAAGAAGCTGACGCTGACTGTTGGCGTGCGCAATCTCTTCGATCAGCTGCCTCCTTGGAGCAATCAAGG
CGATACCACTCCGCAAGGATATGATCCGCGCTTTACCGATGCAGTGGGCCGCGCCTACTTCCTGAAGGCCAATTACAAGA
TGTAA

Upstream 100 bases:

>100_bases
TGACGTTAGTCATTACAAACTTTCACACTCGAATTGCCTTCACTTGGCACGACAAATAGATAAGATCGGCCGCTCACGAG
GCGGCAGGCAATACCTCTAC

Downstream 100 bases:

>100_bases
GCCGCGGGGCATGCGCCCCCGGACGCCGGCTGGCGTCTGGGGGCAATTACGGATTGCGGATGGTCCGTTACAGGAGTTCA
CTTTGCGGTGTCGGGAATGG

Product: TonB-dependent receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 854; Mature: 853

Protein sequence:

>854_residues
MGFGEMMNYKRKTLAIALSLIGSVGYMPLAHADSDSSGTLDRVEVTGSNIKRSISKETAVPMTIIKTDDLVKQGLTSVEQ
VVNSLAANQSSQGANAAVGASTGGAAYASLRGLGHQYTLILLDGRRIVNQPMDGTSVDLNAIPLSVIDRVEVVRDGASAI
YGTDAIGGVINFITKKTMTGLNIGGEFVSPQRSGGKEKSVNISYGYGDLGKDGFNIYGAYDYHKTEKIMATDRDFASTIT
SSTKRSVNSFPANYLNSKGDLVAANPACKPPYSIPDGSGACSELYSLFPSIQPEIEQQTAVLKGTTRLGDHELSLQYMIT
KTKNTTWVAPTPFSGDVTSPTAPGENPANGPFPLYGRSVPAGDRVDSSTATTQRLQFNAEGLIAGWDYRAGLGHSESKVT
HDVVSGYLSQSKLQNALNNGFNPDTEDPAAWAPYASTGQIEQAKSKLDQADFKVSKEVYQLPAGMLAVALGVETRHETIE
HTYNHAVASDTLSTGLTKTTDGSGSRNAQALYAEMDIPVIKHLDANLAVRYDHYSDSGSSVNPKVSLKYQPIPQLLLRTS
ASTGFRAPSLYDINQPNQQQLTAKNYTDPVLCPGGVAQPGAGSNSCVKTQQNLFVGGNKSLNPEKSSSLSFGMVLEPVKD
LTTSVDFWWTNIQNTIGSLNEATIFGNPSKYGNLFVRDGSNNLLYVMDATQNLGNTSAAGVDLGFSYRFPRTAIGTFSVN
LDGTYISKHMFQYEKGGDYHSDLGAYVNGGPTFRWQHNLSLNWSEGAWSGILAQDYKSGYTDDVATHMVKPYSTWNLSGS
YAWDKKLTLTVGVRNLFDQLPPWSNQGDTTPQGYDPRFTDAVGRAYFLKANYKM

Sequences:

>Translated_854_residues
MGFGEMMNYKRKTLAIALSLIGSVGYMPLAHADSDSSGTLDRVEVTGSNIKRSISKETAVPMTIIKTDDLVKQGLTSVEQ
VVNSLAANQSSQGANAAVGASTGGAAYASLRGLGHQYTLILLDGRRIVNQPMDGTSVDLNAIPLSVIDRVEVVRDGASAI
YGTDAIGGVINFITKKTMTGLNIGGEFVSPQRSGGKEKSVNISYGYGDLGKDGFNIYGAYDYHKTEKIMATDRDFASTIT
SSTKRSVNSFPANYLNSKGDLVAANPACKPPYSIPDGSGACSELYSLFPSIQPEIEQQTAVLKGTTRLGDHELSLQYMIT
KTKNTTWVAPTPFSGDVTSPTAPGENPANGPFPLYGRSVPAGDRVDSSTATTQRLQFNAEGLIAGWDYRAGLGHSESKVT
HDVVSGYLSQSKLQNALNNGFNPDTEDPAAWAPYASTGQIEQAKSKLDQADFKVSKEVYQLPAGMLAVALGVETRHETIE
HTYNHAVASDTLSTGLTKTTDGSGSRNAQALYAEMDIPVIKHLDANLAVRYDHYSDSGSSVNPKVSLKYQPIPQLLLRTS
ASTGFRAPSLYDINQPNQQQLTAKNYTDPVLCPGGVAQPGAGSNSCVKTQQNLFVGGNKSLNPEKSSSLSFGMVLEPVKD
LTTSVDFWWTNIQNTIGSLNEATIFGNPSKYGNLFVRDGSNNLLYVMDATQNLGNTSAAGVDLGFSYRFPRTAIGTFSVN
LDGTYISKHMFQYEKGGDYHSDLGAYVNGGPTFRWQHNLSLNWSEGAWSGILAQDYKSGYTDDVATHMVKPYSTWNLSGS
YAWDKKLTLTVGVRNLFDQLPPWSNQGDTTPQGYDPRFTDAVGRAYFLKANYKM
>Mature_853_residues
GFGEMMNYKRKTLAIALSLIGSVGYMPLAHADSDSSGTLDRVEVTGSNIKRSISKETAVPMTIIKTDDLVKQGLTSVEQV
VNSLAANQSSQGANAAVGASTGGAAYASLRGLGHQYTLILLDGRRIVNQPMDGTSVDLNAIPLSVIDRVEVVRDGASAIY
GTDAIGGVINFITKKTMTGLNIGGEFVSPQRSGGKEKSVNISYGYGDLGKDGFNIYGAYDYHKTEKIMATDRDFASTITS
STKRSVNSFPANYLNSKGDLVAANPACKPPYSIPDGSGACSELYSLFPSIQPEIEQQTAVLKGTTRLGDHELSLQYMITK
TKNTTWVAPTPFSGDVTSPTAPGENPANGPFPLYGRSVPAGDRVDSSTATTQRLQFNAEGLIAGWDYRAGLGHSESKVTH
DVVSGYLSQSKLQNALNNGFNPDTEDPAAWAPYASTGQIEQAKSKLDQADFKVSKEVYQLPAGMLAVALGVETRHETIEH
TYNHAVASDTLSTGLTKTTDGSGSRNAQALYAEMDIPVIKHLDANLAVRYDHYSDSGSSVNPKVSLKYQPIPQLLLRTSA
STGFRAPSLYDINQPNQQQLTAKNYTDPVLCPGGVAQPGAGSNSCVKTQQNLFVGGNKSLNPEKSSSLSFGMVLEPVKDL
TTSVDFWWTNIQNTIGSLNEATIFGNPSKYGNLFVRDGSNNLLYVMDATQNLGNTSAAGVDLGFSYRFPRTAIGTFSVNL
DGTYISKHMFQYEKGGDYHSDLGAYVNGGPTFRWQHNLSLNWSEGAWSGILAQDYKSGYTDDVATHMVKPYSTWNLSGSY
AWDKKLTLTVGVRNLFDQLPPWSNQGDTTPQGYDPRFTDAVGRAYFLKANYKM

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=165, Percent_Identity=31.5151515151515, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790405, Length=143, Percent_Identity=32.1678321678322, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 91997; Mature: 91866

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFGEMMNYKRKTLAIALSLIGSVGYMPLAHADSDSSGTLDRVEVTGSNIKRSISKETAV
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHCCC
PMTIIKTDDLVKQGLTSVEQVVNSLAANQSSQGANAAVGASTGGAAYASLRGLGHQYTLI
CEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHCCCCEEEEE
LLDGRRIVNQPMDGTSVDLNAIPLSVIDRVEVVRDGASAIYGTDAIGGVINFITKKTMTG
EECCHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCC
LNIGGEFVSPQRSGGKEKSVNISYGYGDLGKDGFNIYGAYDYHKTEKIMATDRDFASTIT
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCHHEECCCHHHHHHH
SSTKRSVNSFPANYLNSKGDLVAANPACKPPYSIPDGSGACSELYSLFPSIQPEIEQQTA
HHHHHHHHHCCHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
VLKGTTRLGDHELSLQYMITKTKNTTWVAPTPFSGDVTSPTAPGENPANGPFPLYGRSVP
HHCCCCCCCCCEEEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGDRVDSSTATTQRLQFNAEGLIAGWDYRAGLGHSESKVTHDVVSGYLSQSKLQNALNNG
CCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
FNPDTEDPAAWAPYASTGQIEQAKSKLDQADFKVSKEVYQLPAGMLAVALGVETRHETIE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHH
HTYNHAVASDTLSTGLTKTTDGSGSRNAQALYAEMDIPVIKHLDANLAVRYDHYSDSGSS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCCCCCC
VNPKVSLKYQPIPQLLLRTSASTGFRAPSLYDINQPNQQQLTAKNYTDPVLCPGGVAQPG
CCCEEEEEECCHHHHHHHCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCEECCCCCCCCC
AGSNSCVKTQQNLFVGGNKSLNPEKSSSLSFGMVLEPVKDLTTSVDFWWTNIQNTIGSLN
CCCCCCEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEEHHHHHHHCCCC
EATIFGNPSKYGNLFVRDGSNNLLYVMDATQNLGNTSAAGVDLGFSYRFPRTAIGTFSVN
CEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEECCEECCCCCCEEEEEEEE
LDGTYISKHMFQYEKGGDYHSDLGAYVNGGPTFRWQHNLSLNWSEGAWSGILAQDYKSGY
CCCHHHHHHHHHHHCCCCCHHCCCCEECCCCEEEEEECEEEEECCCCCCCHHHHHHCCCC
TDDVATHMVKPYSTWNLSGSYAWDKKLTLTVGVRNLFDQLPPWSNQGDTTPQGYDPRFTD
CHHHHHHHCCCCCEECCCCCEEECCEEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCHHH
AVGRAYFLKANYKM
HHCCEEEEEECCCC
>Mature Secondary Structure 
GFGEMMNYKRKTLAIALSLIGSVGYMPLAHADSDSSGTLDRVEVTGSNIKRSISKETAV
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHCCC
PMTIIKTDDLVKQGLTSVEQVVNSLAANQSSQGANAAVGASTGGAAYASLRGLGHQYTLI
CEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHCCCCEEEEE
LLDGRRIVNQPMDGTSVDLNAIPLSVIDRVEVVRDGASAIYGTDAIGGVINFITKKTMTG
EECCHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCC
LNIGGEFVSPQRSGGKEKSVNISYGYGDLGKDGFNIYGAYDYHKTEKIMATDRDFASTIT
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCHHEECCCHHHHHHH
SSTKRSVNSFPANYLNSKGDLVAANPACKPPYSIPDGSGACSELYSLFPSIQPEIEQQTA
HHHHHHHHHCCHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
VLKGTTRLGDHELSLQYMITKTKNTTWVAPTPFSGDVTSPTAPGENPANGPFPLYGRSVP
HHCCCCCCCCCEEEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGDRVDSSTATTQRLQFNAEGLIAGWDYRAGLGHSESKVTHDVVSGYLSQSKLQNALNNG
CCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
FNPDTEDPAAWAPYASTGQIEQAKSKLDQADFKVSKEVYQLPAGMLAVALGVETRHETIE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHH
HTYNHAVASDTLSTGLTKTTDGSGSRNAQALYAEMDIPVIKHLDANLAVRYDHYSDSGSS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCCCCCC
VNPKVSLKYQPIPQLLLRTSASTGFRAPSLYDINQPNQQQLTAKNYTDPVLCPGGVAQPG
CCCEEEEEECCHHHHHHHCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCEECCCCCCCCC
AGSNSCVKTQQNLFVGGNKSLNPEKSSSLSFGMVLEPVKDLTTSVDFWWTNIQNTIGSLN
CCCCCCEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEEHHHHHHHCCCC
EATIFGNPSKYGNLFVRDGSNNLLYVMDATQNLGNTSAAGVDLGFSYRFPRTAIGTFSVN
CEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEECCEECCCCCCEEEEEEEE
LDGTYISKHMFQYEKGGDYHSDLGAYVNGGPTFRWQHNLSLNWSEGAWSGILAQDYKSGY
CCCHHHHHHHHHHHCCCCCHHCCCCEECCCCEEEEEECEEEEECCCCCCCHHHHHHCCCC
TDDVATHMVKPYSTWNLSGSYAWDKKLTLTVGVRNLFDQLPPWSNQGDTTPQGYDPRFTD
CHHHHHHHCCCCCEECCCCCEEECCEEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCHHH
AVGRAYFLKANYKM
HHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]