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The map label for this gene is uppP

Identifier: 34497384

GI number: 34497384

Start: 2098280

End: 2099110

Strand: Reverse

Name: uppP

Synonym: CV_1929

Alternate gene names: 34497384

Gene position: 2099110-2098280 (Counterclockwise)

Preceding gene: 34497385

Following gene: 34497383

Centisome position: 44.18

GC content: 65.22

Gene sequence:

>831_bases
ATGAACGCGATCGAAGCCTTGCTGTTTGCCGTGATCCAGGGCGTCAGCGAATTATTTCCCGTCAGCAGCCTGGGGCACGG
CGTGCTGATACCCGACTGGCTGCACTGGTCGATCAACCGCACCCATCCCGACTTCCTGCCCTTCATGGTGATGCTGCACC
TGGGCACCGCCGCCGCGCTGCTGATCTATTTCCGCCGCGACTGGGTGGACCTGATCGGCGGCTGGCTGAAAGCCGGCGGA
CGCGCCAGCAACCCGCATGCGCGCCTGATGTGGCTAGTGATCGCCGGCACCCTCCCCGCGGGCCTGCTGGGCCTGCTGCT
GGAAAAGCAGCTGCGCGCGCTGTTCGCCAGCACCACCGCCGTGCTGGTTTTCTTGGCGTTGAACGGCCTGCTGCTGCTGT
GGGGCGACAAGCTGAAGAAGAAAACCGCCTCGCACGAACTGTCCGAACTGAGCTTCGCCGGCGCGATCAAGATCGGCGCC
GGCCAGGCGCTGGCGCTGCTGCCCGGCTTTTCCCGCTCCGGCGCCACATTGGTGGCCGGCCTGGCCCACGGCCTGGACTA
CGCATCCTCCGCCCGTTTCTCCTTCCTGCTCGCCACGCCCATCATCACCGCCGCCGGCCTGCTGGAAATCCCCAAGCTCG
CCCACCGCGGCAACGGTTCCGCCGAGTGGGGCCTGCTGCTGGCCTGCGGCGCCGTCTCCGGGCTTTGCGCCTACGCGAGC
ACCTGGTTCCTGATGCGCTACTTCAAGAAAACCGAGATCGAGTCGCTGCGTCCTTTCGGCTTTTACTGCCTCTTGGTCGG
AGTTGTCGGCTTATTGTTCAAACTCGTGTAA

Upstream 100 bases:

>100_bases
TAAACCGTACAGCTGGCTTGCGCGTTAAGAAGCGGTCATTCTTCGGAACGGGAACGGCGATGCCGTCCCGTTTCTTCCGC
GTCCTATCCAAGGGGGAGCC

Downstream 100 bases:

>100_bases
ACACGCTGCACATGGTCGCGCCTTGATATAAAATGGCATGTGACCAGTAATTCTACGTATTGAAGCACAGACGGCGCCCC
ATAAAGGCGCCATCTGTGTT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNAIEALLFAVIQGVSELFPVSSLGHGVLIPDWLHWSINRTHPDFLPFMVMLHLGTAAALLIYFRRDWVDLIGGWLKAGG
RASNPHARLMWLVIAGTLPAGLLGLLLEKQLRALFASTTAVLVFLALNGLLLLWGDKLKKKTASHELSELSFAGAIKIGA
GQALALLPGFSRSGATLVAGLAHGLDYASSARFSFLLATPIITAAGLLEIPKLAHRGNGSAEWGLLLACGAVSGLCAYAS
TWFLMRYFKKTEIESLRPFGFYCLLVGVVGLLFKLV

Sequences:

>Translated_276_residues
MNAIEALLFAVIQGVSELFPVSSLGHGVLIPDWLHWSINRTHPDFLPFMVMLHLGTAAALLIYFRRDWVDLIGGWLKAGG
RASNPHARLMWLVIAGTLPAGLLGLLLEKQLRALFASTTAVLVFLALNGLLLLWGDKLKKKTASHELSELSFAGAIKIGA
GQALALLPGFSRSGATLVAGLAHGLDYASSARFSFLLATPIITAAGLLEIPKLAHRGNGSAEWGLLLACGAVSGLCAYAS
TWFLMRYFKKTEIESLRPFGFYCLLVGVVGLLFKLV
>Mature_276_residues
MNAIEALLFAVIQGVSELFPVSSLGHGVLIPDWLHWSINRTHPDFLPFMVMLHLGTAAALLIYFRRDWVDLIGGWLKAGG
RASNPHARLMWLVIAGTLPAGLLGLLLEKQLRALFASTTAVLVFLALNGLLLLWGDKLKKKTASHELSELSFAGAIKIGA
GQALALLPGFSRSGATLVAGLAHGLDYASSARFSFLLATPIITAAGLLEIPKLAHRGNGSAEWGLLLACGAVSGLCAYAS
TWFLMRYFKKTEIESLRPFGFYCLLVGVVGLLFKLV

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=278, Percent_Identity=30.5755395683453, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_CHRVO (Q7NWQ2)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901599.1
- GeneID:   2547777
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1929
- NMPDR:   fig|243365.1.peg.1929
- HOGENOM:   HBG391969
- OMA:   VMLHLGT
- ProtClustDB:   PRK00281
- BioCyc:   CVIO243365:CV_1929-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29652; Mature: 29652

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf946bf8)-; HASH(0xddf31a4)-; HASH(0xe9fd30c)-; HASH(0xf9a6ec4)-; HASH(0xd2b0b24)-; HASH(0x10047b7c)-; HASH(0xfc4d134)-; HASH(0xfa15458)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIEALLFAVIQGVSELFPVSSLGHGVLIPDWLHWSINRTHPDFLPFMVMLHLGTAAAL
CCHHHHHHHHHHHHHHHHCCHHHCCCCCEECCHHEEECCCCCCHHHHHHHHHHHHHHHHH
LIYFRRDWVDLIGGWLKAGGRASNPHARLMWLVIAGTLPAGLLGLLLEKQLRALFASTTA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVFLALNGLLLLWGDKLKKKTASHELSELSFAGAIKIGAGQALALLPGFSRSGATLVAG
HHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCCCCCCCHHHHHH
LAHGLDYASSARFSFLLATPIITAAGLLEIPKLAHRGNGSAEWGLLLACGAVSGLCAYAS
HHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TWFLMRYFKKTEIESLRPFGFYCLLVGVVGLLFKLV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNAIEALLFAVIQGVSELFPVSSLGHGVLIPDWLHWSINRTHPDFLPFMVMLHLGTAAAL
CCHHHHHHHHHHHHHHHHCCHHHCCCCCEECCHHEEECCCCCCHHHHHHHHHHHHHHHHH
LIYFRRDWVDLIGGWLKAGGRASNPHARLMWLVIAGTLPAGLLGLLLEKQLRALFASTTA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVFLALNGLLLLWGDKLKKKTASHELSELSFAGAIKIGAGQALALLPGFSRSGATLVAG
HHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCCCCCCCHHHHHH
LAHGLDYASSARFSFLLATPIITAAGLLEIPKLAHRGNGSAEWGLLLACGAVSGLCAYAS
HHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TWFLMRYFKKTEIESLRPFGFYCLLVGVVGLLFKLV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782