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The map label for this gene is cynT [H]

Identifier: 34497336

GI number: 34497336

Start: 2042808

End: 2043467

Strand: Reverse

Name: cynT [H]

Synonym: CV_1881

Alternate gene names: 34497336

Gene position: 2043467-2042808 (Counterclockwise)

Preceding gene: 34497338

Following gene: 34497335

Centisome position: 43.01

GC content: 69.55

Gene sequence:

>660_bases
ATGCAGGACATCATCGCCGGCATCCTCAAATTCCAGCGCGAGGCCTATCCCCGGCGCGCCGAACTGTTTCGCCGGCTGGC
CGGCGACCAATCCCCCGCCACGCTGTTCATCGCCTGCTCCGACAGCCGGGTGGTGCCGGAACTGCTGACTCAGCGCGAGC
CGGGCGATCTGTTCGTGATCCGCAACGCCGGCAACATCGTGCCCGGCTACGGCCAGGAGCCGGGCGGCGTGTCCGCCTCC
GTGGAGTACGCGGTCACCGCGCTGGGCGTGGCCGACATCGTGGTCTGCGGCCATTCCGACTGCGGCGCGATGACGGCGGT
CGCCTGCGGCAAGGACCTGAGCGGAATGCCCGCCGTCGCCGGCTGGCTGCGCCACGCCGACTGCGCCAAGGCGATCAACA
ACGCCGGCGAGCACGACAATCCCGCCGCCAAGGTGGACGCGATGGCGCGCGAAAACGTCATCGCCCAACTGGCCAACCTG
CGCACCCACCCGTCTGTGGCGCTGGCGCTGCAGCAAGGCAGGCTGCGCTTGCACGGCTGGATGTACGACATCGCCAGCGG
CGACGTCCTGGCGCTGGATCCGGAGCAACGCCGTTTCTTGCCGCTGCGGGATTGCCCGCAGACGGCAACCATGCTGGACG
GCGACTGCCGCCAGCCTTGA

Upstream 100 bases:

>100_bases
GTATTGGATATGCCTATTAAAACGATAATTTATCAGTCTTGGACCCAATGAAAAACACGGCGCATCATCCGCTCATCGCT
TCACCACACGGAGAACCGCC

Downstream 100 bases:

>100_bases
CCTGGAGCCGCCGGCCAAACCGCCATCCGGTTTTTGCCGCCGCTCCGCCATCCCCATCCAAGGAGAACCAGAATGCAATC
CCAATGCCAGCCAGCCCCGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MQDIIAGILKFQREAYPRRAELFRRLAGDQSPATLFIACSDSRVVPELLTQREPGDLFVIRNAGNIVPGYGQEPGGVSAS
VEYAVTALGVADIVVCGHSDCGAMTAVACGKDLSGMPAVAGWLRHADCAKAINNAGEHDNPAAKVDAMARENVIAQLANL
RTHPSVALALQQGRLRLHGWMYDIASGDVLALDPEQRRFLPLRDCPQTATMLDGDCRQP

Sequences:

>Translated_219_residues
MQDIIAGILKFQREAYPRRAELFRRLAGDQSPATLFIACSDSRVVPELLTQREPGDLFVIRNAGNIVPGYGQEPGGVSAS
VEYAVTALGVADIVVCGHSDCGAMTAVACGKDLSGMPAVAGWLRHADCAKAINNAGEHDNPAAKVDAMARENVIAQLANL
RTHPSVALALQQGRLRLHGWMYDIASGDVLALDPEQRRFLPLRDCPQTATMLDGDCRQP
>Mature_219_residues
MQDIIAGILKFQREAYPRRAELFRRLAGDQSPATLFIACSDSRVVPELLTQREPGDLFVIRNAGNIVPGYGQEPGGVSAS
VEYAVTALGVADIVVCGHSDCGAMTAVACGKDLSGMPAVAGWLRHADCAKAINNAGEHDNPAAKVDAMARENVIAQLANL
RTHPSVALALQQGRLRLHGWMYDIASGDVLALDPEQRRFLPLRDCPQTATMLDGDCRQP

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=219, Percent_Identity=63.9269406392694, Blast_Score=288, Evalue=1e-79,
Organism=Escherichia coli, GI1786318, Length=174, Percent_Identity=34.4827586206897, Blast_Score=90, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI25147564, Length=259, Percent_Identity=28.1853281853282, Blast_Score=113, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI115532990, Length=252, Percent_Identity=26.5873015873016, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324292, Length=199, Percent_Identity=28.643216080402, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24645213, Length=239, Percent_Identity=26.3598326359833, Blast_Score=97, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23489; Mature: 23489

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDIIAGILKFQREAYPRRAELFRRLAGDQSPATLFIACSDSRVVPELLTQREPGDLFVI
CHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCCEEEE
RNAGNIVPGYGQEPGGVSASVEYAVTALGVADIVVCGHSDCGAMTAVACGKDLSGMPAVA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHEEEECCCCCCHHHHHHCCCCCCCCHHHH
GWLRHADCAKAINNAGEHDNPAAKVDAMARENVIAQLANLRTHPSVALALQQGRLRLHGW
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEEEE
MYDIASGDVLALDPEQRRFLPLRDCPQTATMLDGDCRQP
EEEECCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MQDIIAGILKFQREAYPRRAELFRRLAGDQSPATLFIACSDSRVVPELLTQREPGDLFVI
CHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCCEEEE
RNAGNIVPGYGQEPGGVSASVEYAVTALGVADIVVCGHSDCGAMTAVACGKDLSGMPAVA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHEEEECCCCCCHHHHHHCCCCCCCCHHHH
GWLRHADCAKAINNAGEHDNPAAKVDAMARENVIAQLANLRTHPSVALALQQGRLRLHGW
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEEEE
MYDIASGDVLALDPEQRRFLPLRDCPQTATMLDGDCRQP
EEEECCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]