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The map label for this gene is yfhR [C]

Identifier: 34497320

GI number: 34497320

Start: 2024504

End: 2025337

Strand: Reverse

Name: yfhR [C]

Synonym: CV_1865

Alternate gene names: 34497320

Gene position: 2025337-2024504 (Counterclockwise)

Preceding gene: 34497321

Following gene: 34497318

Centisome position: 42.63

GC content: 44.72

Gene sequence:

>834_bases
ATGACCAAGGCATCCCTGATTTTCCTGATGACTGCTACAATACTGTTAGGCATGTTCTTCTTTGACCATTGGCAGCGGCT
TAAGATATTTGAGCCCGCTCATCAGCTCTACCCCACTCCTGATGAAATGGGGGTGCCATACAAGGACATATGGCTAACGA
TCAGAAATATGGAAAACGAAGACAAGGGCATTCTGCATGGATGGTGGCTACCTAACAAAGAAGCCAGCATGCTGTATTTA
CATGGTAGCGAAAGCACAATAGCCACTGATTTGGATAAGATATTGCAGATATGGAATGCAGGTTATTCGGTGCTTGCTAT
AGATTATAGAGGATTTGGCCAAAGCACTAAAATGCTTCCAAACGAGAACAGCGTGACGGAAGATGCGATGGCGGCCTGGG
ATTACTTGAAGACACTATCCGACTCAAAAAACTTCCACGGCATCTATGGCCACTCGTTAGGAAGCGCCATCGCGATCAAC
ATTGGAAAAAGACACCCCGAGGTGGATTATCTGGTTCTAGAAGGTAGTTTCTCATCGATGGCGGACATCATAAAGGAAAC
TACACCATATAGATGGCTACCTTCCCTCTTGCTGACTCAAAAATTTGAATCCATGAAAAACATTCAAGGCATTGCCATAC
CAAAGCTATTTATACATTGCAGAAGCGATGAGATTGTTCCATTCTTTTTAGGCGAGAAACTTTACCAGGCAGCAGGCCTC
CCTAAAACCAGGCTTATCCTCGAAAAAGGAGGCCATCAAACATGCAGCCATGCTGATGCTGCGCTCTGGAAAAACGCCAT
GAGAATGATAATGAGCAAAAATAGCTCGACATGA

Upstream 100 bases:

>100_bases
TCTGATTATATGCACTGGCGCTCATCACATAATCAGCCATGCATATCTTAATTATTAAGCCACTCACGCGAAAATTTTAA
AAGCGTCCACGGAGTTTGAC

Downstream 100 bases:

>100_bases
ATCAAAAATCTTTTCCTGCGTAACACTTGCAACATGAGGGTAGCCTTTCGGCTACCTCAACTACCTCACTGTTGATTATA
CTGATCAAATACCTAATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTKASLIFLMTATILLGMFFFDHWQRLKIFEPAHQLYPTPDEMGVPYKDIWLTIRNMENEDKGILHGWWLPNKEASMLYL
HGSESTIATDLDKILQIWNAGYSVLAIDYRGFGQSTKMLPNENSVTEDAMAAWDYLKTLSDSKNFHGIYGHSLGSAIAIN
IGKRHPEVDYLVLEGSFSSMADIIKETTPYRWLPSLLLTQKFESMKNIQGIAIPKLFIHCRSDEIVPFFLGEKLYQAAGL
PKTRLILEKGGHQTCSHADAALWKNAMRMIMSKNSST

Sequences:

>Translated_277_residues
MTKASLIFLMTATILLGMFFFDHWQRLKIFEPAHQLYPTPDEMGVPYKDIWLTIRNMENEDKGILHGWWLPNKEASMLYL
HGSESTIATDLDKILQIWNAGYSVLAIDYRGFGQSTKMLPNENSVTEDAMAAWDYLKTLSDSKNFHGIYGHSLGSAIAIN
IGKRHPEVDYLVLEGSFSSMADIIKETTPYRWLPSLLLTQKFESMKNIQGIAIPKLFIHCRSDEIVPFFLGEKLYQAAGL
PKTRLILEKGGHQTCSHADAALWKNAMRMIMSKNSST
>Mature_276_residues
TKASLIFLMTATILLGMFFFDHWQRLKIFEPAHQLYPTPDEMGVPYKDIWLTIRNMENEDKGILHGWWLPNKEASMLYLH
GSESTIATDLDKILQIWNAGYSVLAIDYRGFGQSTKMLPNENSVTEDAMAAWDYLKTLSDSKNFHGIYGHSLGSAIAINI
GKRHPEVDYLVLEGSFSSMADIIKETTPYRWLPSLLLTQKFESMKNIQGIAIPKLFIHCRSDEIVPFFLGEKLYQAAGLP
KTRLILEKGGHQTCSHADAALWKNAMRMIMSKNSST

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI24308097, Length=183, Percent_Identity=34.9726775956284, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI109689718, Length=183, Percent_Identity=34.9726775956284, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI32451492, Length=212, Percent_Identity=33.0188679245283, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI32528310, Length=209, Percent_Identity=32.5358851674641, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI49355781, Length=232, Percent_Identity=28.0172413793103, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI226510965, Length=204, Percent_Identity=26.9607843137255, Blast_Score=75, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137566, Length=268, Percent_Identity=28.3582089552239, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24655464, Length=183, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24655467, Length=183, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 31468; Mature: 31337

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKASLIFLMTATILLGMFFFDHWQRLKIFEPAHQLYPTPDEMGVPYKDIWLTIRNMENE
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCCHHCCCCHHHHEEEEECCCCC
DKGILHGWWLPNKEASMLYLHGSESTIATDLDKILQIWNAGYSVLAIDYRGFGQSTKMLP
CCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
NENSVTEDAMAAWDYLKTLSDSKNFHGIYGHSLGSAIAINIGKRHPEVDYLVLEGSFSSM
CCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEECCCCCCCCEEEEECCHHHH
ADIIKETTPYRWLPSLLLTQKFESMKNIQGIAIPKLFIHCRSDEIVPFFLGEKLYQAAGL
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEECEEEEEECCCCCCHHHHHHHHHHHCCC
PKTRLILEKGGHQTCSHADAALWKNAMRMIMSKNSST
CHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKASLIFLMTATILLGMFFFDHWQRLKIFEPAHQLYPTPDEMGVPYKDIWLTIRNMENE
CCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCCHHCCCCHHHHEEEEECCCCC
DKGILHGWWLPNKEASMLYLHGSESTIATDLDKILQIWNAGYSVLAIDYRGFGQSTKMLP
CCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
NENSVTEDAMAAWDYLKTLSDSKNFHGIYGHSLGSAIAINIGKRHPEVDYLVLEGSFSSM
CCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEECCCCCCCCEEEEECCHHHH
ADIIKETTPYRWLPSLLLTQKFESMKNIQGIAIPKLFIHCRSDEIVPFFLGEKLYQAAGL
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEECEEEEEECCCCCCHHHHHHHHHHHCCC
PKTRLILEKGGHQTCSHADAALWKNAMRMIMSKNSST
CHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]