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The map label for this gene is cysS [H]

Identifier: 34497201

GI number: 34497201

Start: 1897277

End: 1898656

Strand: Direct

Name: cysS [H]

Synonym: CV_1746

Alternate gene names: 34497201

Gene position: 1897277-1898656 (Clockwise)

Preceding gene: 34497200

Following gene: 34497202

Centisome position: 39.93

GC content: 65.72

Gene sequence:

>1380_bases
TTGATCATGCTGAGCCTGTACAACACACTGACCCGCCAGAAGGAAGCGTTCAAACCCATCGAACCCGGCAAAGTGAGCAT
GTACGTCTGTGGCATGACCGTTTACGACCTCTGTCACATCGGCCACGCGCGCATGCTGGCTGCTTTCGACGTGATCTACC
GCTGGCTGAAGGCCTCCGGCTACGATGTGAACTACGTGCGCAACATCACCGACATCGAAGACAAGATCATCAAGCGCGCG
CTGGAGCGCGGCATCACGCCGGAGCAACTGGTGGAGGAAACCATCGCCGACATGCGCCAGGACGCCGCGGCGCTGGGCCT
GCTGCCGCCGACGCACGAGCCGCGCGCCACCCACCACGTGGGCGGCATGGTCGCGATGATCGAACAGCTGATCGCCAACG
GCAAGGCCTATCCGGCCGCCAACGGCGACGTCTACTACGCGGTGCGCGAATTCGAGGGCTACGGCAAGCTGTCCGGCCGC
ACGCTGGACAAGCTGCGCGCCGGCGAGCGCGTGGAAGTGGATCCGAACAAGCGCGACCCGCTGGACTTCGTGCTGTGGAA
GGCCGCCAAGCCGGGCGAGCCGTCCTGGGACAGCCCGTGGGGCAAGGGCCGTCCGGGCTGGCACATCGAGTGCTCGGTGA
TGAGCTGCCACCATCTGGGCGAGCATTTCGACATCCACGGCGGCGGCGAGGACCTGCAGTTCCCGCACCATGAAAACGAG
ATCGCCCAGTCCGAGGGCGCGCACGGCCACCAGTACGTCAACTACTGGCTGCACAACGGCTTCATCAATGTCGACGGCGA
GAAGATGTCCAAGAGCCTGGGCAATTTCTTCACCATCCGCGACGTGCTGCAGCATTTTGACGGCGAGGTGATCCGCTTCT
TCATCGTGCGCAGCCACTACCGCAGCCCGGTCAACTACACCGACAGCATCCTCAACGACGCCAAGCATGGCCTGACCCGG
CTGTACACCGCGCTGCGCGGCATCGAGCTGCCGACGTCCGATGGCATCGACTGGAACCACGCCTACGCCGCCCGTTTCAA
GGCGGCGATGGACGACGACTTCGGCACTTCCGAAGCGGTGGCGGTGCTGTTCGAGCTGGCCGGCGAAGTGAACAAGAGCC
GCGACCCGCAGCTGGCCCGCCTGCTGAAGGACCTGGGCGGTGTGCTGGGCCTGCTCACGCGCGATCCGGAAGTTTTCCTG
CAAGGCGGCGTGGGCGAGGGCGAGCTGTCGGCCGAGCAGGTGGAGGCGCTGATCCAGGCGCGCAAGGACGCGCGCGCCGC
CAAGGACTGGGCCGAATCCGACCGCATCCGCGACGAGCTCACCGCCAAGGGCATCGTGCTGGAGGATGGCGCCGGCGGCA
CCATCTGGCGCCGCGCCTGA

Upstream 100 bases:

>100_bases
CGTTTGCGCATTTCAGCGCGTAATGTCGCGGCTCGAATGACAGAAGCCGGCGCCGCTCTGTTACAATCTCTTTCCTTTGA
ATCATCAACCATAGGTTTTT

Downstream 100 bases:

>100_bases
TCCCGGTTTAGCCGCCAGCGCTTGTCAACGGCGGTCAAACGGCGGATAATGCCATGTTTCGCAAGCAGTACAGGCAAAAC
CCCTGTACCCGATTTGAAAG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MIMLSLYNTLTRQKEAFKPIEPGKVSMYVCGMTVYDLCHIGHARMLAAFDVIYRWLKASGYDVNYVRNITDIEDKIIKRA
LERGITPEQLVEETIADMRQDAAALGLLPPTHEPRATHHVGGMVAMIEQLIANGKAYPAANGDVYYAVREFEGYGKLSGR
TLDKLRAGERVEVDPNKRDPLDFVLWKAAKPGEPSWDSPWGKGRPGWHIECSVMSCHHLGEHFDIHGGGEDLQFPHHENE
IAQSEGAHGHQYVNYWLHNGFINVDGEKMSKSLGNFFTIRDVLQHFDGEVIRFFIVRSHYRSPVNYTDSILNDAKHGLTR
LYTALRGIELPTSDGIDWNHAYAARFKAAMDDDFGTSEAVAVLFELAGEVNKSRDPQLARLLKDLGGVLGLLTRDPEVFL
QGGVGEGELSAEQVEALIQARKDARAAKDWAESDRIRDELTAKGIVLEDGAGGTIWRRA

Sequences:

>Translated_459_residues
MIMLSLYNTLTRQKEAFKPIEPGKVSMYVCGMTVYDLCHIGHARMLAAFDVIYRWLKASGYDVNYVRNITDIEDKIIKRA
LERGITPEQLVEETIADMRQDAAALGLLPPTHEPRATHHVGGMVAMIEQLIANGKAYPAANGDVYYAVREFEGYGKLSGR
TLDKLRAGERVEVDPNKRDPLDFVLWKAAKPGEPSWDSPWGKGRPGWHIECSVMSCHHLGEHFDIHGGGEDLQFPHHENE
IAQSEGAHGHQYVNYWLHNGFINVDGEKMSKSLGNFFTIRDVLQHFDGEVIRFFIVRSHYRSPVNYTDSILNDAKHGLTR
LYTALRGIELPTSDGIDWNHAYAARFKAAMDDDFGTSEAVAVLFELAGEVNKSRDPQLARLLKDLGGVLGLLTRDPEVFL
QGGVGEGELSAEQVEALIQARKDARAAKDWAESDRIRDELTAKGIVLEDGAGGTIWRRA
>Mature_459_residues
MIMLSLYNTLTRQKEAFKPIEPGKVSMYVCGMTVYDLCHIGHARMLAAFDVIYRWLKASGYDVNYVRNITDIEDKIIKRA
LERGITPEQLVEETIADMRQDAAALGLLPPTHEPRATHHVGGMVAMIEQLIANGKAYPAANGDVYYAVREFEGYGKLSGR
TLDKLRAGERVEVDPNKRDPLDFVLWKAAKPGEPSWDSPWGKGRPGWHIECSVMSCHHLGEHFDIHGGGEDLQFPHHENE
IAQSEGAHGHQYVNYWLHNGFINVDGEKMSKSLGNFFTIRDVLQHFDGEVIRFFIVRSHYRSPVNYTDSILNDAKHGLTR
LYTALRGIELPTSDGIDWNHAYAARFKAAMDDDFGTSEAVAVLFELAGEVNKSRDPQLARLLKDLGGVLGLLTRDPEVFL
QGGVGEGELSAEQVEALIQARKDARAAKDWAESDRIRDELTAKGIVLEDGAGGTIWRRA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=412, Percent_Identity=42.4757281553398, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI10835051, Length=232, Percent_Identity=41.8103448275862, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI62240992, Length=232, Percent_Identity=41.8103448275862, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI303304987, Length=232, Percent_Identity=41.8103448275862, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI21269877, Length=232, Percent_Identity=41.8103448275862, Blast_Score=188, Evalue=1e-47,
Organism=Escherichia coli, GI1786737, Length=462, Percent_Identity=57.5757575757576, Blast_Score=524, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI17509797, Length=242, Percent_Identity=40.495867768595, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17509795, Length=242, Percent_Identity=40.495867768595, Blast_Score=179, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=244, Percent_Identity=38.9344262295082, Blast_Score=196, Evalue=8e-51,
Organism=Drosophila melanogaster, GI19922218, Length=394, Percent_Identity=36.5482233502538, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI19922364, Length=226, Percent_Identity=42.4778761061947, Blast_Score=182, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51310; Mature: 51310

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMLSLYNTLTRQKEAFKPIEPGKVSMYVCGMTVYDLCHIGHARMLAAFDVIYRWLKASG
CEEEHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
YDVNYVRNITDIEDKIIKRALERGITPEQLVEETIADMRQDAAALGLLPPTHEPRATHHV
CCHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
GGMVAMIEQLIANGKAYPAANGDVYYAVREFEGYGKLSGRTLDKLRAGERVEVDPNKRDP
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCEEECCCCCCCC
LDFVLWKAAKPGEPSWDSPWGKGRPGWHIECSVMSCHHLGEHFDIHGGGEDLQFPHHENE
HHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEECCCCCCCCCCCCCHH
IAQSEGAHGHQYVNYWLHNGFINVDGEKMSKSLGNFFTIRDVLQHFDGEVIRFFIVRSHY
HHHCCCCCCHHHHHHHHCCCEEEECHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHC
RSPVNYTDSILNDAKHGLTRLYTALRGIELPTSDGIDWNHAYAARFKAAMDDDFGTSEAV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
AVLFELAGEVNKSRDPQLARLLKDLGGVLGLLTRDPEVFLQGGVGEGELSAEQVEALIQA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCHHHHHHHHHH
RKDARAAKDWAESDRIRDELTAKGIVLEDGAGGTIWRRA
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MIMLSLYNTLTRQKEAFKPIEPGKVSMYVCGMTVYDLCHIGHARMLAAFDVIYRWLKASG
CEEEHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
YDVNYVRNITDIEDKIIKRALERGITPEQLVEETIADMRQDAAALGLLPPTHEPRATHHV
CCHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
GGMVAMIEQLIANGKAYPAANGDVYYAVREFEGYGKLSGRTLDKLRAGERVEVDPNKRDP
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCEEECCCCCCCC
LDFVLWKAAKPGEPSWDSPWGKGRPGWHIECSVMSCHHLGEHFDIHGGGEDLQFPHHENE
HHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEECCCCCCCCCCCCCHH
IAQSEGAHGHQYVNYWLHNGFINVDGEKMSKSLGNFFTIRDVLQHFDGEVIRFFIVRSHY
HHHCCCCCCHHHHHHHHCCCEEEECHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHC
RSPVNYTDSILNDAKHGLTRLYTALRGIELPTSDGIDWNHAYAARFKAAMDDDFGTSEAV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
AVLFELAGEVNKSRDPQLARLLKDLGGVLGLLTRDPEVFLQGGVGEGELSAEQVEALIQA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCHHHHHHHHHH
RKDARAAKDWAESDRIRDELTAKGIVLEDGAGGTIWRRA
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]