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The map label for this gene is kdpA

Identifier: 34497054

GI number: 34497054

Start: 1724814

End: 1726622

Strand: Reverse

Name: kdpA

Synonym: CV_1599

Alternate gene names: 34497054

Gene position: 1726622-1724814 (Counterclockwise)

Preceding gene: 34497055

Following gene: 34497053

Centisome position: 36.34

GC content: 65.95

Gene sequence:

>1809_bases
ATGAGCACACCCGCCATGCTGCAACTAGGGCTGTTCTTGGTTGTGCTGATCGCGCTGGCCTGGCCGCTGGGCGCCTACAT
GACGCGCGTCATGCAGGGGGAGAACATCGGCCCGGCGCGCTGGTGCGCGCCGCTGGAACGCGGCTTTTACCGCCTCGCCG
GCATCAAGCAGGAGGAGGAGATGGGCTGGCGCGGCTACGCGGTGGCGCTGATCCTGTTCAACGTGCTGGGCGTGGCCGCC
GTCTACGCGCTGCAACGGCTGCAAGGCATGCTGCCGTTCAATCCGCAGGCGATGGCCGCGGTATCGCCCGACTCCTCGTT
CAACACCGCCATTTCCTTCGTCACCAATACCAACTGGCAAGGCTATGGCGGCGAAACCACGATGAGCTACCTGACCCAGA
TGCTGGGTCTGACGGTGCAGAACTTCGTGTCCGCCGCCACCGGCGCCGCGGTGGTGATCGCGCTGATCCGCGGCTTCGCC
CGCCACAGCAGTGCCAAGATCGGCAATTTCTGGGTCGACGTCACCCGGATGACGCTGTACGTGCTGCTGCCGCTGGCTGT
GGTATTCGCGCTGGTTTTCACCCAGCAGGGCGCCATCCAGAACCTGTCCGCCTACCAGGACGTCCATACCGTCGAAACCG
TCAAATACCAGCAGCCCAAGCAGGACGCCAAGGGCAACCCGGTGCTGGGCAAGGACGGCAAACCCGTCATGGAGGACAAG
ACCAGCCAGACGCAAACCCTGCCCATGGGCCCGGTGGCCTCGCAGGAAGCAATCAAGATGCTGGGCACCAACGGCGGCGG
CTTCTTCAACGCCAACTCCGCCCACCCGTTTGAGAACCCGACCCCGCTGGCCAACTTCCTGCAGGACATCGCGATCTTCC
TGATCCCGGCCGCGCTGTGCTTCTTGTTCGGCCGCATGGTCGGCGACCGCCGCCAAGGCTGGGCCATCCTCGCCGCGATG
ACCATCATGTTCGCCACCGCGGTGGTGGTGGAAACCCGCGCCGAGCAGGCCGGCGTGCCGCAATACAGCTCGCTGGGCAT
AGACCAGCGCGCCAGCCAGCTGCAATCCGGCGGCAATATGGAAGGCAAGGAAGCCCGCTTCGGCATCATCGACACCTCGC
TGTTCGTCGCCGTGACCACCTCCGCCTCCTGCGGCGCGGTCAACGCGATGCACGACTCGCTGACGCCGATCGGCGGCCTG
GTGCCGATGTTCCTGATGCAGTTGGGCGAAGTGGTGTTCGGCGGCGTCGGCTCCGGCCTGTACGGCATGCTGATCTTCGC
CATCCTGGCGGTGTTCATCGCCGGCCTGATGGTGGGTCGCACGCCGGAATACCTGGGCAAGAAGATCGAAACCTACGAGA
TGAAGATGACCGCGATCACCATCCTGGTGACGCCGACCCTGGTGCTGGCGCTGACCGCGATCGCCGTCAGCCTGGCCGCC
GGCAAGGCCGGCATCGCCAATCCGGCCGCGCACGGCTTCAGCGAGATCCTGTACGCGTTCACCTCGGCCGCCAACAACAA
CGGCAGCGCCTTCGCCGGCCTGTCCGCCAACACGCCGTTCTACAACATCATGACCGGCCTCGCGATGTTCTTCGGCCGCT
TCTTCATGATCGTGCCCATCCTGGCCATCGCCGGCTCGCTGGCCGCCAAGAAGCGCCTGGCCGTCACCGGCGGCACCCTG
CCCACCCACGGCCCGCTGTTCGTGACGCTGCTGATCGGCACCGTGCTGCTGGTGGGCGCCCTCAACTATGTTCCGGCCCT
GGCGCTGGGGCCGGTGGTCGAGCACCTGCAAATGCTCGCCGCCCGCTAA

Upstream 100 bases:

>100_bases
GGCAAGCAATGACCGCCTGGTACCTGATCAGCGCCCTGCTGGCGCTGGGACTGTTCGTCTATCTGATCTACGCATTGGTC
AAACCGGAGAATTTCTAATC

Downstream 100 bases:

>100_bases
GCCCGTCAGTCAAGGAAATTCGATATGAACGACAACAATCATTCCAAACCGCTGGCGGCGGCCCCCGACGCCGGCCACAA
GAGCGCGAGCAAGTCGCTGC

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MSTPAMLQLGLFLVVLIALAWPLGAYMTRVMQGENIGPARWCAPLERGFYRLAGIKQEEEMGWRGYAVALILFNVLGVAA
VYALQRLQGMLPFNPQAMAAVSPDSSFNTAISFVTNTNWQGYGGETTMSYLTQMLGLTVQNFVSAATGAAVVIALIRGFA
RHSSAKIGNFWVDVTRMTLYVLLPLAVVFALVFTQQGAIQNLSAYQDVHTVETVKYQQPKQDAKGNPVLGKDGKPVMEDK
TSQTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPFENPTPLANFLQDIAIFLIPAALCFLFGRMVGDRRQGWAILAAM
TIMFATAVVVETRAEQAGVPQYSSLGIDQRASQLQSGGNMEGKEARFGIIDTSLFVAVTTSASCGAVNAMHDSLTPIGGL
VPMFLMQLGEVVFGGVGSGLYGMLIFAILAVFIAGLMVGRTPEYLGKKIETYEMKMTAITILVTPTLVLALTAIAVSLAA
GKAGIANPAAHGFSEILYAFTSAANNNGSAFAGLSANTPFYNIMTGLAMFFGRFFMIVPILAIAGSLAAKKRLAVTGGTL
PTHGPLFVTLLIGTVLLVGALNYVPALALGPVVEHLQMLAAR

Sequences:

>Translated_602_residues
MSTPAMLQLGLFLVVLIALAWPLGAYMTRVMQGENIGPARWCAPLERGFYRLAGIKQEEEMGWRGYAVALILFNVLGVAA
VYALQRLQGMLPFNPQAMAAVSPDSSFNTAISFVTNTNWQGYGGETTMSYLTQMLGLTVQNFVSAATGAAVVIALIRGFA
RHSSAKIGNFWVDVTRMTLYVLLPLAVVFALVFTQQGAIQNLSAYQDVHTVETVKYQQPKQDAKGNPVLGKDGKPVMEDK
TSQTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPFENPTPLANFLQDIAIFLIPAALCFLFGRMVGDRRQGWAILAAM
TIMFATAVVVETRAEQAGVPQYSSLGIDQRASQLQSGGNMEGKEARFGIIDTSLFVAVTTSASCGAVNAMHDSLTPIGGL
VPMFLMQLGEVVFGGVGSGLYGMLIFAILAVFIAGLMVGRTPEYLGKKIETYEMKMTAITILVTPTLVLALTAIAVSLAA
GKAGIANPAAHGFSEILYAFTSAANNNGSAFAGLSANTPFYNIMTGLAMFFGRFFMIVPILAIAGSLAAKKRLAVTGGTL
PTHGPLFVTLLIGTVLLVGALNYVPALALGPVVEHLQMLAAR
>Mature_601_residues
STPAMLQLGLFLVVLIALAWPLGAYMTRVMQGENIGPARWCAPLERGFYRLAGIKQEEEMGWRGYAVALILFNVLGVAAV
YALQRLQGMLPFNPQAMAAVSPDSSFNTAISFVTNTNWQGYGGETTMSYLTQMLGLTVQNFVSAATGAAVVIALIRGFAR
HSSAKIGNFWVDVTRMTLYVLLPLAVVFALVFTQQGAIQNLSAYQDVHTVETVKYQQPKQDAKGNPVLGKDGKPVMEDKT
SQTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPFENPTPLANFLQDIAIFLIPAALCFLFGRMVGDRRQGWAILAAMT
IMFATAVVVETRAEQAGVPQYSSLGIDQRASQLQSGGNMEGKEARFGIIDTSLFVAVTTSASCGAVNAMHDSLTPIGGLV
PMFLMQLGEVVFGGVGSGLYGMLIFAILAVFIAGLMVGRTPEYLGKKIETYEMKMTAITILVTPTLVLALTAIAVSLAAG
KAGIANPAAHGFSEILYAFTSAANNNGSAFAGLSANTPFYNIMTGLAMFFGRFFMIVPILAIAGSLAAKKRLAVTGGTLP
THGPLFVTLLIGTVLLVGALNYVPALALGPVVEHLQMLAAR

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=597, Percent_Identity=57.1189279731993, Blast_Score=653, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_CHRVO (Q7NXM7)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901269.1
- GeneID:   2547343
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1599
- NMPDR:   fig|243365.1.peg.1599
- HOGENOM:   HBG291815
- OMA:   MSYLTQM
- PhylomeDB:   Q7NXM7
- ProtClustDB:   PRK05482
- BioCyc:   CVIO243365:CV_1599-MONOMER
- BRENDA:   3.6.3.12
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 63869; Mature: 63738

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf8f787c)-; HASH(0xf93f790)-; HASH(0xea5a5b0)-; HASH(0xf28f6b8)-; HASH(0xf3141c0)-; HASH(0xcf9e6fc)-; HASH(0xf1e61d8)-; HASH(0xf43eedc)-; HASH(0xe31ffc4)-; HASH(0xf994924)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPAMLQLGLFLVVLIALAWPLGAYMTRVMQGENIGPARWCAPLERGFYRLAGIKQEEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
MGWRGYAVALILFNVLGVAAVYALQRLQGMLPFNPQAMAAVSPDSSFNTAISFVTNTNWQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHEEEEECCCCC
GYGGETTMSYLTQMLGLTVQNFVSAATGAAVVIALIRGFARHSSAKIGNFWVDVTRMTLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLLPLAVVFALVFTQQGAIQNLSAYQDVHTVETVKYQQPKQDAKGNPVLGKDGKPVMEDK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
TSQTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPFENPTPLANFLQDIAIFLIPAALC
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FLFGRMVGDRRQGWAILAAMTIMFATAVVVETRAEQAGVPQYSSLGIDQRASQLQSGGNM
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCC
EGKEARFGIIDTSLFVAVTTSASCGAVNAMHDSLTPIGGLVPMFLMQLGEVVFGGVGSGL
CCCCCEEEEEEHHEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
YGMLIFAILAVFIAGLMVGRTPEYLGKKIETYEMKMTAITILVTPTLVLALTAIAVSLAA
HHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHC
GKAGIANPAAHGFSEILYAFTSAANNNGSAFAGLSANTPFYNIMTGLAMFFGRFFMIVPI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAIAGSLAAKKRLAVTGGTLPTHGPLFVTLLIGTVLLVGALNYVPALALGPVVEHLQMLA
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AR
CH
>Mature Secondary Structure 
STPAMLQLGLFLVVLIALAWPLGAYMTRVMQGENIGPARWCAPLERGFYRLAGIKQEEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
MGWRGYAVALILFNVLGVAAVYALQRLQGMLPFNPQAMAAVSPDSSFNTAISFVTNTNWQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHEEEEECCCCC
GYGGETTMSYLTQMLGLTVQNFVSAATGAAVVIALIRGFARHSSAKIGNFWVDVTRMTLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLLPLAVVFALVFTQQGAIQNLSAYQDVHTVETVKYQQPKQDAKGNPVLGKDGKPVMEDK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
TSQTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPFENPTPLANFLQDIAIFLIPAALC
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FLFGRMVGDRRQGWAILAAMTIMFATAVVVETRAEQAGVPQYSSLGIDQRASQLQSGGNM
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCC
EGKEARFGIIDTSLFVAVTTSASCGAVNAMHDSLTPIGGLVPMFLMQLGEVVFGGVGSGL
CCCCCEEEEEEHHEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
YGMLIFAILAVFIAGLMVGRTPEYLGKKIETYEMKMTAITILVTPTLVLALTAIAVSLAA
HHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHC
GKAGIANPAAHGFSEILYAFTSAANNNGSAFAGLSANTPFYNIMTGLAMFFGRFFMIVPI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAIAGSLAAKKRLAVTGGTLPTHGPLFVTLLIGTVLLVGALNYVPALALGPVVEHLQMLA
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AR
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500782