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The map label for this gene is kdpE [H]

Identifier: 34497050

GI number: 34497050

Start: 1718575

End: 1719309

Strand: Reverse

Name: kdpE [H]

Synonym: CV_1595

Alternate gene names: 34497050

Gene position: 1719309-1718575 (Counterclockwise)

Preceding gene: 34497051

Following gene: 34497049

Centisome position: 36.19

GC content: 65.44

Gene sequence:

>735_bases
ATGAACGACGCCCCCATTTCCGTAGTGATCATCGAGGACGAGAAGCCGATCCGCCGCTTCCTGTCCGCCGCGCTGGAAGA
GGAAAAACTCACCGTCTACGAAGCGGAAACCGGCAAGCAGGGACAGATCGAGGTGGCCACCCGCAAGCCCGATCTGGTCA
TCCTGGACCTGGGGCTTCCGGACATGAACGGCATAGACGTGATCAAGAGCCTGCGCGAATGGACCGACATCCCCATCCTG
GTGCTGTCGGCGCGCACTCAGGAGACCGAAAAGGTAGCGGCGCTGGACGCCGGCGCCGACGACTACCTGACCAAGCCCTT
CGGCGTGGCCGAATGCCTGGCGCGGATCCGGGTGCTGCTGCGCCGGCGCATCCACGGCAGCGCCGCGCCGCAGCAAACCT
TCCAGTTCGGCGACATCCGCGTCGACCTGGTCAACCGCCTGGTGCACAAGGGCGACGCGCCGGTGCATCTGACGCCGATC
GAATACCGGCTGCTGTCCACGCTGATCCGCAACGCCGGCAAGGTGATCACCCACCGCGAACTGCTGCTCGCGGTCTGGGG
CCCGTCCTTCTCCGAACACAACCAGTACCTGCGCGTCTACATGGGCCATTTGCGGCAGAAGCTGGAAGACAACCCCGCGA
TGCCGCGCCACATCGTCACCGAAACCGGCGTCGGCTACCGACTGATCGAAAACGCGCCGGAACAGCCGGCCCGCGATGCC
GCGGCCCAGGGTTGA

Upstream 100 bases:

>100_bases
ACGCGCAGCCGCACGGCGCCCGCTTCTCCTTCACGCTGCCGGCCGGCTCTCCGCCCGAGCTGCCGCCGGAAGACGCCTGA
AACCACAAGAGCGACAAGAC

Downstream 100 bases:

>100_bases
CAGCCCGCTGCCATCGGCATAGTCTAATGTTCATGCGCCGATTTGACACAGCTTGCGGGCGCTCGATAAATGCCAGCTAA
AGCGTATCCGGATCAACCCG

Product: kdp operon transcriptional regulatory protein kdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MNDAPISVVIIEDEKPIRRFLSAALEEEKLTVYEAETGKQGQIEVATRKPDLVILDLGLPDMNGIDVIKSLREWTDIPIL
VLSARTQETEKVAALDAGADDYLTKPFGVAECLARIRVLLRRRIHGSAAPQQTFQFGDIRVDLVNRLVHKGDAPVHLTPI
EYRLLSTLIRNAGKVITHRELLLAVWGPSFSEHNQYLRVYMGHLRQKLEDNPAMPRHIVTETGVGYRLIENAPEQPARDA
AAQG

Sequences:

>Translated_244_residues
MNDAPISVVIIEDEKPIRRFLSAALEEEKLTVYEAETGKQGQIEVATRKPDLVILDLGLPDMNGIDVIKSLREWTDIPIL
VLSARTQETEKVAALDAGADDYLTKPFGVAECLARIRVLLRRRIHGSAAPQQTFQFGDIRVDLVNRLVHKGDAPVHLTPI
EYRLLSTLIRNAGKVITHRELLLAVWGPSFSEHNQYLRVYMGHLRQKLEDNPAMPRHIVTETGVGYRLIENAPEQPARDA
AAQG
>Mature_244_residues
MNDAPISVVIIEDEKPIRRFLSAALEEEKLTVYEAETGKQGQIEVATRKPDLVILDLGLPDMNGIDVIKSLREWTDIPIL
VLSARTQETEKVAALDAGADDYLTKPFGVAECLARIRVLLRRRIHGSAAPQQTFQFGDIRVDLVNRLVHKGDAPVHLTPI
EYRLLSTLIRNAGKVITHRELLLAVWGPSFSEHNQYLRVYMGHLRQKLEDNPAMPRHIVTETGVGYRLIENAPEQPARDA
AAQG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=59.6412556053812, Blast_Score=290, Evalue=6e-80,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=38.3928571428571, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=35.4260089686099, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=32.5892857142857, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=29.5652173913043, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.5892857142857, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=30.3571428571429, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.7017543859649, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=34.4827586206897, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=34.2105263157895, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=31.2236286919831, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=29.8701298701299, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=27.8481012658228, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=29.6943231441048, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790299, Length=176, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27309; Mature: 27309

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAPISVVIIEDEKPIRRFLSAALEEEKLTVYEAETGKQGQIEVATRKPDLVILDLGLP
CCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCC
DMNGIDVIKSLREWTDIPILVLSARTQETEKVAALDAGADDYLTKPFGVAECLARIRVLL
CCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHH
RRRIHGSAAPQQTFQFGDIRVDLVNRLVHKGDAPVHLTPIEYRLLSTLIRNAGKVITHRE
HHHHCCCCCCHHHHEECCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCHHHHH
LLLAVWGPSFSEHNQYLRVYMGHLRQKLEDNPAMPRHIVTETGVGYRLIENAPEQPARDA
HEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHCCCCCCCHHHC
AAQG
CCCC
>Mature Secondary Structure
MNDAPISVVIIEDEKPIRRFLSAALEEEKLTVYEAETGKQGQIEVATRKPDLVILDLGLP
CCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCC
DMNGIDVIKSLREWTDIPILVLSARTQETEKVAALDAGADDYLTKPFGVAECLARIRVLL
CCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHH
RRRIHGSAAPQQTFQFGDIRVDLVNRLVHKGDAPVHLTPIEYRLLSTLIRNAGKVITHRE
HHHHCCCCCCHHHHEECCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCCCCHHHHH
LLLAVWGPSFSEHNQYLRVYMGHLRQKLEDNPAMPRHIVTETGVGYRLIENAPEQPARDA
HEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHCCCCCCCHHHC
AAQG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]