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The map label for this gene is cheR [H]

Identifier: 34497035

GI number: 34497035

Start: 1701173

End: 1702786

Strand: Direct

Name: cheR [H]

Synonym: CV_1580

Alternate gene names: 34497035

Gene position: 1701173-1702786 (Clockwise)

Preceding gene: 34497034

Following gene: 34497036

Centisome position: 35.81

GC content: 66.85

Gene sequence:

>1614_bases
ATGCTGGAGTTGCTGCAAGGACCGGCGGAGCAGGCGCTGGACCTGAGCTTTTACGACGCCGATCTGTTGGGCGCGGAGCT
GTTGTGCGCGATCGCCGACCGCCTGGACCGGGGCGGCAAGCTGAAGATCCACGCCTACCACGCCTTGCTGGCGCACGGCC
TGATGCGGCTGAACCTGCCGGCCAGGCTGGTGTCGAGCCAGCCGCCTTCCGAGGCCAGACCGTGGCCGCGCGCGCTGGCG
CTGGCCGGCTCTGCGCAGAGCCTGGACTGCATCCTGCGCATCATCGAATGCCTGCCGCTGTCCGACATGGCGGTGTTCGT
CGCCCAGCACGTGCAGGAAAGCCAGATCAACCTGCTTGATCAGTTGCTGAAGTCGAGGACGGACTACGCGGTGGAGATGC
CGCAGAATATGGCGCCTGTGCGGCCGGGAACGATCTATGTGGCGCCGCCCGGCCACCACATGCGGGTGGGGCACGGTTAC
GTCTACCTGACGCGCGACCGCCAGATACAGTTCGCGCGGCCGTCCATCGATGTGCTGTTCGAGTCGCTGGCCGGCGAGTA
CGGCGCGGAAACGCTGGCGGCGCTGCTGTGCGGTTTCGGCCAGGATGGCGCGGACGGCTGCGCCGCGCTGCGCGCCGCCG
GCGCCTGCGTGATCGTCCAGGATGGCGGAGAATGCGCGCCGGCGCGAGTGATGCCGGACGCCGCGCGCAAGGCCGGGCAT
TACGACTATGTGATGAAGCTGTCCGCCATCGCCAGCGTCGCGGCGGCGGCGGCCGCCGGGCCGGACGCCCAGCCGGACGG
AGAACTGCTGGAGCGCTTCCTGTCCGCGCTGGTCTGCCACTACGGCTACGATTTCCGCAATTACCAGCGGGACAGTCTGA
AACGCCGCATCCACAACCTGATGGGCCAGTTCAACCTGGGGCGCTTCGCCGATTTCCAACGCGCGGTGCTGACCGATGTC
GGGCTGTTCGAGCGGCTGTGCGTCGAACTGCCGGTGGGGGTGACCAGTTTTTTCCGCCACCCGGAGCAGTTGAAGCTGCT
GCGGGACGAGATCCTGCCCTATCTGTCCAGTTTTCCGCTGATCAAGCTGTGGTCCGCCGGCTGCTCCAGCGGAGAGGAGG
CGTATTCGCTGGCCATCGTGCTGGACGAGCTGGGCCTGCTGGACCGCAGCCATCTGTTCGCCACCGACTTCAATCCTTAT
TCGCTGGCGCAAGGCAGCAGCGCGCTGTTTCCCGCCCAGGCGCTGGAGGAAAACCGCGCCAACTACCTGGCGGGCGGCGG
CACGCGGCTGTTCGACGCCTACCTGTCCCGCAACGGGCGTTTTCTGCGGGTGGACGACCATTTGCGCCAGCGCATCCTGT
TCTATCGCCACTCGCTGACCGACGAAGGCATCTTCAACGAGTTCCAGCTCATCGTCTGCCGCAACGTGCTGATCTATTTC
GACGGCGAGCTGCAGCGGCAGGTGCTGCGGCGTTTCGCGCAGTCGCTGCACGCCGAGGGTTTCCTGGTGCTGGGGCCGCA
GGACGGCTTGCATCGGGCGGCGCTGGAGGCCGGGTTCGAGCTCTACCGCAGCGGCAGCCACATTTACCGCCTTGGCCGGA
GCGTCGGATCATGA

Upstream 100 bases:

>100_bases
GCGAGGGCCGGGGCCGGTGAGCGTCGCCGTTCAGCGGCGATCCGGGCAGTGCCGGGTCGCGATACTGGGGAGGCTGGACG
CGCCGGAGGACCGCGCCGCC

Downstream 100 bases:

>100_bases
GCCGGAAATTCGTCATCCTGGTAGTGGACGACAACATCAACAACCGCGTCACCCTGCAGGCCCTGCTGAGCCGGCTGGAC
GACTGCGAGGTGCTGGAGGC

Product: two-component hybrid sensor-regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MLELLQGPAEQALDLSFYDADLLGAELLCAIADRLDRGGKLKIHAYHALLAHGLMRLNLPARLVSSQPPSEARPWPRALA
LAGSAQSLDCILRIIECLPLSDMAVFVAQHVQESQINLLDQLLKSRTDYAVEMPQNMAPVRPGTIYVAPPGHHMRVGHGY
VYLTRDRQIQFARPSIDVLFESLAGEYGAETLAALLCGFGQDGADGCAALRAAGACVIVQDGGECAPARVMPDAARKAGH
YDYVMKLSAIASVAAAAAAGPDAQPDGELLERFLSALVCHYGYDFRNYQRDSLKRRIHNLMGQFNLGRFADFQRAVLTDV
GLFERLCVELPVGVTSFFRHPEQLKLLRDEILPYLSSFPLIKLWSAGCSSGEEAYSLAIVLDELGLLDRSHLFATDFNPY
SLAQGSSALFPAQALEENRANYLAGGGTRLFDAYLSRNGRFLRVDDHLRQRILFYRHSLTDEGIFNEFQLIVCRNVLIYF
DGELQRQVLRRFAQSLHAEGFLVLGPQDGLHRAALEAGFELYRSGSHIYRLGRSVGS

Sequences:

>Translated_537_residues
MLELLQGPAEQALDLSFYDADLLGAELLCAIADRLDRGGKLKIHAYHALLAHGLMRLNLPARLVSSQPPSEARPWPRALA
LAGSAQSLDCILRIIECLPLSDMAVFVAQHVQESQINLLDQLLKSRTDYAVEMPQNMAPVRPGTIYVAPPGHHMRVGHGY
VYLTRDRQIQFARPSIDVLFESLAGEYGAETLAALLCGFGQDGADGCAALRAAGACVIVQDGGECAPARVMPDAARKAGH
YDYVMKLSAIASVAAAAAAGPDAQPDGELLERFLSALVCHYGYDFRNYQRDSLKRRIHNLMGQFNLGRFADFQRAVLTDV
GLFERLCVELPVGVTSFFRHPEQLKLLRDEILPYLSSFPLIKLWSAGCSSGEEAYSLAIVLDELGLLDRSHLFATDFNPY
SLAQGSSALFPAQALEENRANYLAGGGTRLFDAYLSRNGRFLRVDDHLRQRILFYRHSLTDEGIFNEFQLIVCRNVLIYF
DGELQRQVLRRFAQSLHAEGFLVLGPQDGLHRAALEAGFELYRSGSHIYRLGRSVGS
>Mature_537_residues
MLELLQGPAEQALDLSFYDADLLGAELLCAIADRLDRGGKLKIHAYHALLAHGLMRLNLPARLVSSQPPSEARPWPRALA
LAGSAQSLDCILRIIECLPLSDMAVFVAQHVQESQINLLDQLLKSRTDYAVEMPQNMAPVRPGTIYVAPPGHHMRVGHGY
VYLTRDRQIQFARPSIDVLFESLAGEYGAETLAALLCGFGQDGADGCAALRAAGACVIVQDGGECAPARVMPDAARKAGH
YDYVMKLSAIASVAAAAAAGPDAQPDGELLERFLSALVCHYGYDFRNYQRDSLKRRIHNLMGQFNLGRFADFQRAVLTDV
GLFERLCVELPVGVTSFFRHPEQLKLLRDEILPYLSSFPLIKLWSAGCSSGEEAYSLAIVLDELGLLDRSHLFATDFNPY
SLAQGSSALFPAQALEENRANYLAGGGTRLFDAYLSRNGRFLRVDDHLRQRILFYRHSLTDEGIFNEFQLIVCRNVLIYF
DGELQRQVLRRFAQSLHAEGFLVLGPQDGLHRAALEAGFELYRSGSHIYRLGRSVGS

Specific function: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP [H]

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheR-type methyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=219, Percent_Identity=29.2237442922374, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788193, Length=253, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 59297; Mature: 59297

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50123 CHER ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELLQGPAEQALDLSFYDADLLGAELLCAIADRLDRGGKLKIHAYHALLAHGLMRLNLP
CCCCCCCCHHHHHCCEECCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCC
ARLVSSQPPSEARPWPRALALAGSAQSLDCILRIIECLPLSDMAVFVAQHVQESQINLLD
HHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QLLKSRTDYAVEMPQNMAPVRPGTIYVAPPGHHMRVGHGYVYLTRDRQIQFARPSIDVLF
HHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCEEECCCEEEEEECCEEEEECCHHHHHH
ESLAGEYGAETLAALLCGFGQDGADGCAALRAAGACVIVQDGGECAPARVMPDAARKAGH
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHCCC
YDYVMKLSAIASVAAAAAAGPDAQPDGELLERFLSALVCHYGYDFRNYQRDSLKRRIHNL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHH
MGQFNLGRFADFQRAVLTDVGLFERLCVELPVGVTSFFRHPEQLKLLRDEILPYLSSFPL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCH
IKLWSAGCSSGEEAYSLAIVLDELGLLDRSHLFATDFNPYSLAQGSSALFPAQALEENRA
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHCCCCCCCCCCHHHHHHCCC
NYLAGGGTRLFDAYLSRNGRFLRVDDHLRQRILFYRHSLTDEGIFNEFQLIVCRNVLIYF
CEECCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEE
DGELQRQVLRRFAQSLHAEGFLVLGPQDGLHRAALEAGFELYRSGSHIYRLGRSVGS
CCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MLELLQGPAEQALDLSFYDADLLGAELLCAIADRLDRGGKLKIHAYHALLAHGLMRLNLP
CCCCCCCCHHHHHCCEECCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCC
ARLVSSQPPSEARPWPRALALAGSAQSLDCILRIIECLPLSDMAVFVAQHVQESQINLLD
HHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QLLKSRTDYAVEMPQNMAPVRPGTIYVAPPGHHMRVGHGYVYLTRDRQIQFARPSIDVLF
HHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCEEECCCEEEEEECCEEEEECCHHHHHH
ESLAGEYGAETLAALLCGFGQDGADGCAALRAAGACVIVQDGGECAPARVMPDAARKAGH
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHCCC
YDYVMKLSAIASVAAAAAAGPDAQPDGELLERFLSALVCHYGYDFRNYQRDSLKRRIHNL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHH
MGQFNLGRFADFQRAVLTDVGLFERLCVELPVGVTSFFRHPEQLKLLRDEILPYLSSFPL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCH
IKLWSAGCSSGEEAYSLAIVLDELGLLDRSHLFATDFNPYSLAQGSSALFPAQALEENRA
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHCCCCCCCCCCHHHHHHCCC
NYLAGGGTRLFDAYLSRNGRFLRVDDHLRQRILFYRHSLTDEGIFNEFQLIVCRNVLIYF
CEECCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEE
DGELQRQVLRRFAQSLHAEGFLVLGPQDGLHRAALEAGFELYRSGSHIYRLGRSVGS
CCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]