Click here to switch to the map view.

The map label for this gene is cbiC [H]

Identifier: 34497022

GI number: 34497022

Start: 1679853

End: 1681418

Strand: Reverse

Name: cbiC [H]

Synonym: CV_1567

Alternate gene names: 34497022

Gene position: 1681418-1679853 (Counterclockwise)

Preceding gene: 34497023

Following gene: 34497021

Centisome position: 35.39

GC content: 70.31

Gene sequence:

>1566_bases
ATGAGCCAGCCAGACTACGCCATCGTGCTGGCCGGCCACGGCAGCCGCGACCCGGACGGGGTCAACGAGTTCATGCAGCT
GGTGGACGCGCTGAAGGCGCGCGCCGGCGAGCGCCCCGTCGCCCACGGTTTTCTGGAGTTCGCCCGCCCGACCATAGACG
AGGCGGTGCAGCAGGTGATCGCCGCCGGCGCCAAGACCGTGGTGATGGTGCCCGGCGTGCTGTTGGCCGCCACCCACGCC
AAGAACGACATGCCCAGCGAGCTGTTGGCGCTGCAGCAGGCGCATCCCGGCGTGACGTTCCACTTCGGCGCGGCGCTGGA
CCTGCATCCGCGGCTGCTGGCGCTGTGCCGCCAGCGCATCGTCGAGGCCGAGGCCGCGTCGCCGCAGACCATCTCGCGCA
ACGACGCCTGTCTGGTGGTGGTGGGCCGCGGCACCTCGGACCCGGACGCCAATTCCGAAATCTCCAAGCTCGCGCGCATG
CTGGAGGAAGGCCTGGGCTTCGCCGCGTCCTTCGTCTGCTACTCCGGCACCGCCAAGCCGCTGGTGGCGGACGGCCTGCG
CGCCGCCGCCATGCTGGGCTACCGCCGCATCGTGGTGCTGCCCTACTTCCTGTTCGACGGCGTGCTGGTCAAGCGCATCT
ACGGCGCGGCGGCGGACCTGGCGGCGCGCCATCCGGAAATCGAGGTGCTCAGCGCCGGCTACCTGGGCCCGGATGCCCAA
GTGGCCGAGGTGTTCCTGGAGAGGGCGCGGGAAGGCGTGGAAGGCCGCGCCGCGATGAACTGCGCGCTGTGCAAGTACCG
GGTGCAGATCGTCGGCTTCGAGCAGCAGGTGGGCGAGCCGCAGCGCGGCCACCACGGCAAGGTGCGCGGCCTGCTGGAGC
GCGAGCCTGCCGCCAATCAGCCGCCGGCCTGGAAACGCTACACCCCGCATCCTATCGAGGCGGAAAGCATGCGCATCATA
GACGAAGGCCGCGACTGGTCAGCCTTCCCGGCCGAGCAGCGCACCGCGCTGATGCGGCTGGTGCACACCACCGGCGACTT
CAACAGCGTCGACGACCTGTTCTTCTCGCCCGGCGCCTGCGAAACCGGCATGCGGGCGCTGCTGCGCTGCCGCCGCGTGG
TCACCGACGTCACCATGGTGGAAACCGGGCTGAAACGCGAAGTGCTGCGCCAGCTGGAAGTGGAAACCTGGTGCGGCGTG
CACGACGAGGAAACCCGGCTGCTGGCCGAGGCCAGCGGCCTCACCCGCTCCGCCGCCGGCATCCGCCGCGCCTGGCAGAA
ATTCGGCAACGACTGCGTGGTGGCGATAGGCGACGCGCCGACGGCGATCCGCGAGGTGGTGCGCTTGGTGCGCGAGCACG
GCTGGCGGCCGCAGCTGGTGGTGGGCCTGCCGGTGGGCTTCGTCGGCACCCGCGAATGCAAGGAAGAGCTGCGCGCGCTG
CTGCAAGTGCCGCGCATCACCAACCGCGGCACCCGCGGCGGCTCGCCGTGGGCGGCCACCGTGGTCAACGCGCTGATGAT
AGACGCGATCGAACACGTCCATCAGCAGCAACAACGGGAAGAATGA

Upstream 100 bases:

>100_bases
GCACGCTGGCCGAGTGCGCCGAGCAGCGCTTCTCCGACATGAGCATCATGCTGATCCGCACGCTCGCGCCGATGGACAGC
CAGATCGAGCCGACCCACAA

Downstream 100 bases:

>100_bases
ACCCGGTGCGCCAGCCTTACGACCTCGCCGCCCCCGCCCCCAACGGCATGCGCCGCGGCCGCACCACCGGCAGCTGCGCC
ACCGCCGCCGTCAAGGCGGC

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: CbiXL [H]

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSQPDYAIVLAGHGSRDPDGVNEFMQLVDALKARAGERPVAHGFLEFARPTIDEAVQQVIAAGAKTVVMVPGVLLAATHA
KNDMPSELLALQQAHPGVTFHFGAALDLHPRLLALCRQRIVEAEAASPQTISRNDACLVVVGRGTSDPDANSEISKLARM
LEEGLGFAASFVCYSGTAKPLVADGLRAAAMLGYRRIVVLPYFLFDGVLVKRIYGAAADLAARHPEIEVLSAGYLGPDAQ
VAEVFLERAREGVEGRAAMNCALCKYRVQIVGFEQQVGEPQRGHHGKVRGLLEREPAANQPPAWKRYTPHPIEAESMRII
DEGRDWSAFPAEQRTALMRLVHTTGDFNSVDDLFFSPGACETGMRALLRCRRVVTDVTMVETGLKREVLRQLEVETWCGV
HDEETRLLAEASGLTRSAAGIRRAWQKFGNDCVVAIGDAPTAIREVVRLVREHGWRPQLVVGLPVGFVGTRECKEELRAL
LQVPRITNRGTRGGSPWAATVVNALMIDAIEHVHQQQQREE

Sequences:

>Translated_521_residues
MSQPDYAIVLAGHGSRDPDGVNEFMQLVDALKARAGERPVAHGFLEFARPTIDEAVQQVIAAGAKTVVMVPGVLLAATHA
KNDMPSELLALQQAHPGVTFHFGAALDLHPRLLALCRQRIVEAEAASPQTISRNDACLVVVGRGTSDPDANSEISKLARM
LEEGLGFAASFVCYSGTAKPLVADGLRAAAMLGYRRIVVLPYFLFDGVLVKRIYGAAADLAARHPEIEVLSAGYLGPDAQ
VAEVFLERAREGVEGRAAMNCALCKYRVQIVGFEQQVGEPQRGHHGKVRGLLEREPAANQPPAWKRYTPHPIEAESMRII
DEGRDWSAFPAEQRTALMRLVHTTGDFNSVDDLFFSPGACETGMRALLRCRRVVTDVTMVETGLKREVLRQLEVETWCGV
HDEETRLLAEASGLTRSAAGIRRAWQKFGNDCVVAIGDAPTAIREVVRLVREHGWRPQLVVGLPVGFVGTRECKEELRAL
LQVPRITNRGTRGGSPWAATVVNALMIDAIEHVHQQQQREE
>Mature_520_residues
SQPDYAIVLAGHGSRDPDGVNEFMQLVDALKARAGERPVAHGFLEFARPTIDEAVQQVIAAGAKTVVMVPGVLLAATHAK
NDMPSELLALQQAHPGVTFHFGAALDLHPRLLALCRQRIVEAEAASPQTISRNDACLVVVGRGTSDPDANSEISKLARML
EEGLGFAASFVCYSGTAKPLVADGLRAAAMLGYRRIVVLPYFLFDGVLVKRIYGAAADLAARHPEIEVLSAGYLGPDAQV
AEVFLERAREGVEGRAAMNCALCKYRVQIVGFEQQVGEPQRGHHGKVRGLLEREPAANQPPAWKRYTPHPIEAESMRIID
EGRDWSAFPAEQRTALMRLVHTTGDFNSVDDLFFSPGACETGMRALLRCRRVVTDVTMVETGLKREVLRQLEVETWCGVH
DEETRLLAEASGLTRSAAGIRRAWQKFGNDCVVAIGDAPTAIREVVRLVREHGWRPQLVVGLPVGFVGTRECKEELRALL
QVPRITNRGTRGGSPWAATVVNALMIDAIEHVHQQQQREE

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. CbiXL subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 56967; Mature: 56836

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPDYAIVLAGHGSRDPDGVNEFMQLVDALKARAGERPVAHGFLEFARPTIDEAVQQVI
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
AAGAKTVVMVPGVLLAATHAKNDMPSELLALQQAHPGVTFHFGAALDLHPRLLALCRQRI
HCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCEECCCHHHHHHHHHHH
VEAEAASPQTISRNDACLVVVGRGTSDPDANSEISKLARMLEEGLGFAASFVCYSGTAKP
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
LVADGLRAAAMLGYRRIVVLPYFLFDGVLVKRIYGAAADLAARHPEIEVLSAGYLGPDAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
VAEVFLERAREGVEGRAAMNCALCKYRVQIVGFEQQVGEPQRGHHGKVRGLLEREPAANQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHCCCCCCC
PPAWKRYTPHPIEAESMRIIDEGRDWSAFPAEQRTALMRLVHTTGDFNSVDDLFFSPGAC
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCC
ETGMRALLRCRRVVTDVTMVETGLKREVLRQLEVETWCGVHDEETRLLAEASGLTRSAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
IRRAWQKFGNDCVVAIGDAPTAIREVVRLVREHGWRPQLVVGLPVGFVGTRECKEELRAL
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
LQVPRITNRGTRGGSPWAATVVNALMIDAIEHVHQQQQREE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQPDYAIVLAGHGSRDPDGVNEFMQLVDALKARAGERPVAHGFLEFARPTIDEAVQQVI
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHH
AAGAKTVVMVPGVLLAATHAKNDMPSELLALQQAHPGVTFHFGAALDLHPRLLALCRQRI
HCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCEECCCHHHHHHHHHHH
VEAEAASPQTISRNDACLVVVGRGTSDPDANSEISKLARMLEEGLGFAASFVCYSGTAKP
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
LVADGLRAAAMLGYRRIVVLPYFLFDGVLVKRIYGAAADLAARHPEIEVLSAGYLGPDAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
VAEVFLERAREGVEGRAAMNCALCKYRVQIVGFEQQVGEPQRGHHGKVRGLLEREPAANQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHCCCCCCC
PPAWKRYTPHPIEAESMRIIDEGRDWSAFPAEQRTALMRLVHTTGDFNSVDDLFFSPGAC
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCC
ETGMRALLRCRRVVTDVTMVETGLKREVLRQLEVETWCGVHDEETRLLAEASGLTRSAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
IRRAWQKFGNDCVVAIGDAPTAIREVVRLVREHGWRPQLVVGLPVGFVGTRECKEELRAL
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
LQVPRITNRGTRGGSPWAATVVNALMIDAIEHVHQQQQREE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 12917443 [H]