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The map label for this gene is fabF [H]

Identifier: 34496996

GI number: 34496996

Start: 1658228

End: 1659478

Strand: Direct

Name: fabF [H]

Synonym: CV_1541

Alternate gene names: 34496996

Gene position: 1658228-1659478 (Clockwise)

Preceding gene: 34496994

Following gene: 34496997

Centisome position: 34.9

GC content: 59.95

Gene sequence:

>1251_bases
ATGGCAAATCGTAGAGTGGTAGTAACCGGATATGGTTCTTTGACCTCTCTGGGGGAGAACTCTGCCGAGGCGTGGGAAGC
CATCATGAATGGCAAGCTGGGTTATCGAAAATTCGAGTTGGAAAACCAGCAAATCAAGGCCAAGTTCTTTTCATTTTTGG
ATGAGAATAAAGCGCGCTATCGAGGCATCCCCAAGGCCATTTCCCGCGCCTTGCCGGCATTCGCCAAAAATGCGGTTGTG
GCGGCCCGGGAAGCGATCGATATGGCTTTCGGTAGCCCGGAGGCTATTGCGGAACATTATCCGGCGCATGAATGCGGCGT
CATCATCGGCACGGGGTGGGGGGGGCTCGATGAAGCGTACGACATCCGCGACGCTTATCGCGATACCGGATTCGGCAGTC
CTTTGGGCAGCCTGATTTCCATGCCTAGCATCGCCACCGGAGCTTGCACGCTGATGTGGAATCTGCGCGGCTACCAGAAT
ACGGTGATCGCGGCTTGCGCCACGGGCACCATCGCGATAGGCGACGCGTATGAGGCGATTCGGCAAGGGCGCGCCAGCAT
GATGCTGGCTGGCGGTTCCGAGACGCTGCGCAATGAAACCAATATCTGGAACATCGACGTGCTCAATGCTTTGAGCAAGG
AGCAGGAGGAAGCGGAGAGGGCCTGCTGCCCGTTTGACCGCCGCCGGTCCGGTTTCGTGCTCGCCGAGGGCGCGGCGGTG
TTGTGTCTGGAGGAGTTGGAGCATGCTCAGCACCGCGGCGCCACCATACTGGGCGAGATCAAGGGTTATGGCAGCTTTTC
CGACGCCCGCGATTTCACCGCCCCGGCCGAGGACATGCTGGCCCGCGTCAAGTCGATCGAATTCGCGCTCAAGCAGGCCG
GCAAGCGGCCGGAGGACATCGACTACATCAATGCTCACGGCACGTCGACGCCGTTGAATGACTTGAACGAATCCAACGCC
ATCAAGGCCGCTTTGGGGGCGCATGCGAAGCGTGTCCCGGTGTCCAGCACCAAGTCGTACAGCGGCCACCTGATCTCCGC
TGCGGGCAGTTTCGAATCCATCATCTGCTTGAAGGCCATCGCGACCGGCATCCTGCCTGGCACCGCTAATCTGCTGGAAT
CCGATCCCGAGTGCGACCTCAACTATCTGCCGAACGGGCACCTGCATGGCCAAGCGGTGGACACCACTCTCAACCTCAGC
TTCGGCTTCGGCGGCGCAAACGCGGCGCTGGTGATAGAAAGGGCGCGTTGA

Upstream 100 bases:

>100_bases
TTTGATGCGATTAACTTCGCAGGGGATCTTTTTGCCTCTTGCCGGCTTGTGATTTGTGATTTTTTAATTAATTAATTCTG
ATCTGCAATAAGGAAGTGTC

Downstream 100 bases:

>100_bases
TGCTGCTCAGTTTCGACAACAAGGCGATCGCGGATTGGGCGAAGCTGTCCGGAGACTACAACCCCATCCATTTTGAAGTG
GAGCGGGCGAGGGAAACCGG

Product: 3-oxoacyl-ACP synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MANRRVVVTGYGSLTSLGENSAEAWEAIMNGKLGYRKFELENQQIKAKFFSFLDENKARYRGIPKAISRALPAFAKNAVV
AAREAIDMAFGSPEAIAEHYPAHECGVIIGTGWGGLDEAYDIRDAYRDTGFGSPLGSLISMPSIATGACTLMWNLRGYQN
TVIAACATGTIAIGDAYEAIRQGRASMMLAGGSETLRNETNIWNIDVLNALSKEQEEAERACCPFDRRRSGFVLAEGAAV
LCLEELEHAQHRGATILGEIKGYGSFSDARDFTAPAEDMLARVKSIEFALKQAGKRPEDIDYINAHGTSTPLNDLNESNA
IKAALGAHAKRVPVSSTKSYSGHLISAAGSFESIICLKAIATGILPGTANLLESDPECDLNYLPNGHLHGQAVDTTLNLS
FGFGGANAALVIERAR

Sequences:

>Translated_416_residues
MANRRVVVTGYGSLTSLGENSAEAWEAIMNGKLGYRKFELENQQIKAKFFSFLDENKARYRGIPKAISRALPAFAKNAVV
AAREAIDMAFGSPEAIAEHYPAHECGVIIGTGWGGLDEAYDIRDAYRDTGFGSPLGSLISMPSIATGACTLMWNLRGYQN
TVIAACATGTIAIGDAYEAIRQGRASMMLAGGSETLRNETNIWNIDVLNALSKEQEEAERACCPFDRRRSGFVLAEGAAV
LCLEELEHAQHRGATILGEIKGYGSFSDARDFTAPAEDMLARVKSIEFALKQAGKRPEDIDYINAHGTSTPLNDLNESNA
IKAALGAHAKRVPVSSTKSYSGHLISAAGSFESIICLKAIATGILPGTANLLESDPECDLNYLPNGHLHGQAVDTTLNLS
FGFGGANAALVIERAR
>Mature_415_residues
ANRRVVVTGYGSLTSLGENSAEAWEAIMNGKLGYRKFELENQQIKAKFFSFLDENKARYRGIPKAISRALPAFAKNAVVA
AREAIDMAFGSPEAIAEHYPAHECGVIIGTGWGGLDEAYDIRDAYRDTGFGSPLGSLISMPSIATGACTLMWNLRGYQNT
VIAACATGTIAIGDAYEAIRQGRASMMLAGGSETLRNETNIWNIDVLNALSKEQEEAERACCPFDRRRSGFVLAEGAAVL
CLEELEHAQHRGATILGEIKGYGSFSDARDFTAPAEDMLARVKSIEFALKQAGKRPEDIDYINAHGTSTPLNDLNESNAI
KAALGAHAKRVPVSSTKSYSGHLISAAGSFESIICLKAIATGILPGTANLLESDPECDLNYLPNGHLHGQAVDTTLNLSF
GFGGANAALVIERAR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=437, Percent_Identity=35.2402745995423, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI223972627, Length=165, Percent_Identity=44.2424242424242, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI41872631, Length=272, Percent_Identity=29.0441176470588, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1787337, Length=415, Percent_Identity=34.9397590361446, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1788663, Length=419, Percent_Identity=31.5035799522673, Blast_Score=168, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71983541, Length=420, Percent_Identity=30.7142857142857, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=36.9811320754717, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17550940, Length=434, Percent_Identity=25.3456221198157, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=280, Percent_Identity=25.3571428571429, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=32.2869955156951, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=37.3493975903614, Blast_Score=234, Evalue=8e-62,
Organism=Drosophila melanogaster, GI221330659, Length=274, Percent_Identity=28.8321167883212, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920632, Length=274, Percent_Identity=28.8321167883212, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=26.5682656826568, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44542; Mature: 44411

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRRVVVTGYGSLTSLGENSAEAWEAIMNGKLGYRKFELENQQIKAKFFSFLDENKARY
CCCCEEEEEECCCHHHCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCHHH
RGIPKAISRALPAFAKNAVVAAREAIDMAFGSPEAIAEHYPAHECGVIIGTGWGGLDEAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCCCCCCHHH
DIRDAYRDTGFGSPLGSLISMPSIATGACTLMWNLRGYQNTVIAACATGTIAIGDAYEAI
HHHHHHHCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCEEEECHHHHHH
RQGRASMMLAGGSETLRNETNIWNIDVLNALSKEQEEAERACCPFDRRRSGFVLAEGAAV
HCCCCEEEEECCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHH
LCLEELEHAQHRGATILGEIKGYGSFSDARDFTAPAEDMLARVKSIEFALKQAGKRPEDI
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DYINAHGTSTPLNDLNESNAIKAALGAHAKRVPVSSTKSYSGHLISAAGSFESIICLKAI
CEEECCCCCCCHHHCCCCCHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
ATGILPGTANLLESDPECDLNYLPNGHLHGQAVDTTLNLSFGFGGANAALVIERAR
HHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
ANRRVVVTGYGSLTSLGENSAEAWEAIMNGKLGYRKFELENQQIKAKFFSFLDENKARY
CCCEEEEEECCCHHHCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCHHH
RGIPKAISRALPAFAKNAVVAAREAIDMAFGSPEAIAEHYPAHECGVIIGTGWGGLDEAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCCCCCCHHH
DIRDAYRDTGFGSPLGSLISMPSIATGACTLMWNLRGYQNTVIAACATGTIAIGDAYEAI
HHHHHHHCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCEEEECHHHHHH
RQGRASMMLAGGSETLRNETNIWNIDVLNALSKEQEEAERACCPFDRRRSGFVLAEGAAV
HCCCCEEEEECCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHH
LCLEELEHAQHRGATILGEIKGYGSFSDARDFTAPAEDMLARVKSIEFALKQAGKRPEDI
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DYINAHGTSTPLNDLNESNAIKAALGAHAKRVPVSSTKSYSGHLISAAGSFESIICLKAI
CEEECCCCCCCHHHCCCCCHHHHHHCCCHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
ATGILPGTANLLESDPECDLNYLPNGHLHGQAVDTTLNLSFGFGGANAALVIERAR
HHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]