Click here to switch to the map view.

The map label for this gene is aruB

Identifier: 34496955

GI number: 34496955

Start: 1604617

End: 1605963

Strand: Direct

Name: aruB

Synonym: CV_1500

Alternate gene names: 34496955

Gene position: 1604617-1605963 (Clockwise)

Preceding gene: 34496954

Following gene: 34496956

Centisome position: 33.77

GC content: 68.3

Gene sequence:

>1347_bases
ATGAACGCCTATGAAGTGAATTTCGACGGACTGGTCGGCCCGACCCACAATTACAGCGGCCTGTCCTTCGGCAACGTCGC
CTCCACCAGCAACGTCAGCGCGGCGTCCAACCCCAAGCTGGCGGCCAAGCAGGGCCTGCAGAAGATGAAGGCGCTGTACG
ACCTGGGCTTCAAGCAGGGCGTGCTGGCGCCGCAGGAGCGGCCCGACGTGGCGTCCTTGCGCCGGCTGGGCTTCGGCGGC
AGCGACGCCGAGGTGATCGCCCGCGCGGCGAAGGAAGCGCCCACCATCCTGGCGGCGGCGACGTCGGCGTCCTGCATGTG
GACCGCCAACGCGGCCACCGTCAGCCCGTCGGCCGACACCGCCGACGGCCGCGTGCATTTCACGCCGGCCAATCTGAACA
ACAAGTTCCACCGCTCGATCGAGCACCCGACCACTCGCCGCGTGCTGCGGGCGATGTTCGCCGACGAGACGCGTTTCGCG
GTGCATGAGGCGTTGCCGGCGCAGATGCACTTCGGCGACGAAGGCGCGGCCAACCATACCCGTTTCTGCGCGGATTACGG
CCAGCCGGGCGTGGAGTTCTTCGTGTTCGGCGCGGCGGCCTTCGACATGCGCTATCCGAAGCCGGCCAAGTTCCCGGCGC
GGCAGACGCTGGAGGCCAGCCAGGCGGTGGCCAGGCTGCACGGCCTGTCCGAGGCCGGCGTGGTGTACGCGCAGCAGGAT
CCGGACACCATCGACGCCGGCGTGTTCCACAACGACGTGATCTCGGTCGGCAACGGCGAAGTGCTGTTCCACCATCAGCA
GGCCTTCCTCAACCAGGCCGACGTGCTGGACGAGATTGCCCGCAAGCTGGAAGCGCGCGGCGGCCGCTTCACGGCCATCG
AGGTGCCGCGCGCCGAGGTGACGGTGGAGGAGGCGGTGAAGAGCTATCTGTTCAACAGCCAGCTGCTGTCCAAGCCGGGC
GGCAAGATGCTGATCGTGGTGCCGGAAGAGTGCCGCAACAGCGAGCGGGTGTGGAGCTATCTGCAGAAGCTGGCGGCCAG
CGGCGGACCGATCGACGAGGTCCGGGTGTTCGACCTGAAGCAGAGCATGCAGAACGGCGGCGGCCCCGCCTGCCTGCGCC
TGCGCGTGGCGCTGAACCAGGCGGAACTGGCCGCGGTGAATCCCAAGGTGCTGATGAGCGACGCGTTGTTCGCATCGCTC
AACGGCTGGGTGGACCGCCACTACCGCGACCGCCTGGCGCCGGAGGACCTGGCCGATCCGCAGCTGCTGATCGAATGCCG
CGGCGCGCTGGACGAGTTGACCGGCATCCTGGGCCTGGGCAGCGTCTATCCCTTCCAGCTGGCCTGA

Upstream 100 bases:

>100_bases
GCGGCCGACTACTGCGCCTACCCGGTGGCCTCGCTGGAGTGCGACAGCCTGGCGCTGCCGGCCCAGCTGTCGCCCGGCAT
CGTGCTGTGAGGGGAAGACG

Downstream 100 bases:

>100_bases
GGCGTTTTTCCAACGCACAGCCCGTCCCGCGAAACCGGGGCGGGTTTTTTCTTGTCCGCGCCATTTAGCGGCTGTTAACA
AATTGCTTGCCGGTTATTCC

Product: succinylarginine dihydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNAYEVNFDGLVGPTHNYSGLSFGNVASTSNVSAASNPKLAAKQGLQKMKALYDLGFKQGVLAPQERPDVASLRRLGFGG
SDAEVIARAAKEAPTILAAATSASCMWTANAATVSPSADTADGRVHFTPANLNNKFHRSIEHPTTRRVLRAMFADETRFA
VHEALPAQMHFGDEGAANHTRFCADYGQPGVEFFVFGAAAFDMRYPKPAKFPARQTLEASQAVARLHGLSEAGVVYAQQD
PDTIDAGVFHNDVISVGNGEVLFHHQQAFLNQADVLDEIARKLEARGGRFTAIEVPRAEVTVEEAVKSYLFNSQLLSKPG
GKMLIVVPEECRNSERVWSYLQKLAASGGPIDEVRVFDLKQSMQNGGGPACLRLRVALNQAELAAVNPKVLMSDALFASL
NGWVDRHYRDRLAPEDLADPQLLIECRGALDELTGILGLGSVYPFQLA

Sequences:

>Translated_448_residues
MNAYEVNFDGLVGPTHNYSGLSFGNVASTSNVSAASNPKLAAKQGLQKMKALYDLGFKQGVLAPQERPDVASLRRLGFGG
SDAEVIARAAKEAPTILAAATSASCMWTANAATVSPSADTADGRVHFTPANLNNKFHRSIEHPTTRRVLRAMFADETRFA
VHEALPAQMHFGDEGAANHTRFCADYGQPGVEFFVFGAAAFDMRYPKPAKFPARQTLEASQAVARLHGLSEAGVVYAQQD
PDTIDAGVFHNDVISVGNGEVLFHHQQAFLNQADVLDEIARKLEARGGRFTAIEVPRAEVTVEEAVKSYLFNSQLLSKPG
GKMLIVVPEECRNSERVWSYLQKLAASGGPIDEVRVFDLKQSMQNGGGPACLRLRVALNQAELAAVNPKVLMSDALFASL
NGWVDRHYRDRLAPEDLADPQLLIECRGALDELTGILGLGSVYPFQLA
>Mature_448_residues
MNAYEVNFDGLVGPTHNYSGLSFGNVASTSNVSAASNPKLAAKQGLQKMKALYDLGFKQGVLAPQERPDVASLRRLGFGG
SDAEVIARAAKEAPTILAAATSASCMWTANAATVSPSADTADGRVHFTPANLNNKFHRSIEHPTTRRVLRAMFADETRFA
VHEALPAQMHFGDEGAANHTRFCADYGQPGVEFFVFGAAAFDMRYPKPAKFPARQTLEASQAVARLHGLSEAGVVYAQQD
PDTIDAGVFHNDVISVGNGEVLFHHQQAFLNQADVLDEIARKLEARGGRFTAIEVPRAEVTVEEAVKSYLFNSQLLSKPG
GKMLIVVPEECRNSERVWSYLQKLAASGGPIDEVRVFDLKQSMQNGGGPACLRLRVALNQAELAAVNPKVLMSDALFASL
NGWVDRHYRDRLAPEDLADPQLLIECRGALDELTGILGLGSVYPFQLA

Specific function: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)

COG id: COG3724

COG function: function code E; Succinylarginine dihydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinylarginine dihydrolase family

Homologues:

Organism=Escherichia coli, GI1788041, Length=446, Percent_Identity=58.9686098654709, Blast_Score=535, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTB_CHRVO (Q7NXX6)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901170.1
- HSSP:   P76216
- ProteinModelPortal:   Q7NXX6
- SMR:   Q7NXX6
- GeneID:   2549954
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1500
- NMPDR:   fig|243365.1.peg.1500
- HOGENOM:   HBG289862
- OMA:   HFAHHPA
- PhylomeDB:   Q7NXX6
- ProtClustDB:   PRK13281
- BioCyc:   CVIO243365:CV_1500-MONOMER
- BRENDA:   3.5.3.23
- HAMAP:   MF_01172
- InterPro:   IPR007079
- Gene3D:   G3DSA:3.75.10.20
- TIGRFAMs:   TIGR03241

Pfam domain/function: PF04996 AstB

EC number: =3.5.3.23

Molecular weight: Translated: 48439; Mature: 48439

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: ACT_SITE 174-174 ACT_SITE 250-250 ACT_SITE 371-371 BINDING 110-110 BINDING 214-214 BINDING 252-252 BINDING 365-365

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAYEVNFDGLVGPTHNYSGLSFGNVASTSNVSAASNPKLAAKQGLQKMKALYDLGFKQG
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
VLAPQERPDVASLRRLGFGGSDAEVIARAAKEAPTILAAATSASCMWTANAATVSPSADT
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEECCCCCC
ADGRVHFTPANLNNKFHRSIEHPTTRRVLRAMFADETRFAVHEALPAQMHFGDEGAANHT
CCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCCCH
RFCADYGQPGVEFFVFGAAAFDMRYPKPAKFPARQTLEASQAVARLHGLSEAGVVYAQQD
HHHHHCCCCCCEEEEEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
PDTIDAGVFHNDVISVGNGEVLFHHQQAFLNQADVLDEIARKLEARGGRFTAIEVPRAEV
CCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
TVEEAVKSYLFNSQLLSKPGGKMLIVVPEECRNSERVWSYLQKLAASGGPIDEVRVFDLK
HHHHHHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHHHHHCCCCCCCEEHHHHH
QSMQNGGGPACLRLRVALNQAELAAVNPKVLMSDALFASLNGWVDRHYRDRLAPEDLADP
HHHHCCCCCEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QLLIECRGALDELTGILGLGSVYPFQLA
HHHHHHHHHHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure
MNAYEVNFDGLVGPTHNYSGLSFGNVASTSNVSAASNPKLAAKQGLQKMKALYDLGFKQG
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
VLAPQERPDVASLRRLGFGGSDAEVIARAAKEAPTILAAATSASCMWTANAATVSPSADT
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEECCCCCC
ADGRVHFTPANLNNKFHRSIEHPTTRRVLRAMFADETRFAVHEALPAQMHFGDEGAANHT
CCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCCCH
RFCADYGQPGVEFFVFGAAAFDMRYPKPAKFPARQTLEASQAVARLHGLSEAGVVYAQQD
HHHHHCCCCCCEEEEEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
PDTIDAGVFHNDVISVGNGEVLFHHQQAFLNQADVLDEIARKLEARGGRFTAIEVPRAEV
CCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
TVEEAVKSYLFNSQLLSKPGGKMLIVVPEECRNSERVWSYLQKLAASGGPIDEVRVFDLK
HHHHHHHHHHHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHHHHHCCCCCCCEEHHHHH
QSMQNGGGPACLRLRVALNQAELAAVNPKVLMSDALFASLNGWVDRHYRDRLAPEDLADP
HHHHCCCCCEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QLLIECRGALDELTGILGLGSVYPFQLA
HHHHHHHHHHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782