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The map label for this gene is chb [H]

Identifier: 34496948

GI number: 34496948

Start: 1594364

End: 1597000

Strand: Direct

Name: chb [H]

Synonym: CV_1493

Alternate gene names: 34496948

Gene position: 1594364-1597000 (Clockwise)

Preceding gene: 34496947

Following gene: 34496950

Centisome position: 33.56

GC content: 70.65

Gene sequence:

>2637_bases
ATGAACGTGAAGCGATTGCTGGGCGCGGCCGTGCTGGCCGCCTTGTCGGCGTGGGCGTGGGCCGCGCCGGATGCGGCGGC
GCTGGGGCAGAGCCTGTCGCTGAAAATTGCGGTGGACAGCAACAAGGGCGCGGCCGCCGGCGCGCCGTGCGCCGACCTGG
GGGCGGACTGGGCATCCTGCCTGAAGGGGCGGCTGATCCTGGAAAACAAGGGCGGGCAGGCGGTGCCGGCCGGCGGCGGC
TGGAACCTGTATCTGCACAGCATCCGCCGCATCCTGAAGCTGGACACGCCGCAGTTCACCCTCCGCCACATCACCGGCGA
CCTGTACCAGATCACCCCCACCGCCGCCTTCCAGGGCCTGGCGCCGGGGCAGAAGCTGGAGCTGCCGCTGATAGACGAAT
ACTGGATCCTGCAGGAAAGCGACGTGCTGCCGCGCCCCTACGTGACGGTGGACGGCCAGCCGCCGGCGTTGCTGCGGCAT
GACAGCAGCGACGAGGCCAGCTATTTGCTGCCCTTGAGCGGCGACAACTGGAAAAACCCGGCCGGCGAGCTGCGGCCGCT
GGCCACGCCGGAGCAGCGTTACCGCGCCTTCAGCCTGCGCGGGACGCAGCTGTCGGCGGCGCAGGCGGCCAACCGGACCA
TCCCTGCGGTGCGGCGTCAGCAGCTGGGCGGCGGCGAGCTCTTGGTGCGCGGCGTCAGCCTGAACCTGTCCGGCGTCAGC
CCGGCGCAGCAGGACGCGCTGGCCGGGCGCGCGGCGCAGCTGGAGCTGCGCGCGGGCGGCACGCGGGTGGAGGGCGGCGT
GGTCGGCGCCAAGCTGCCGGCCGACATCGCCGTGCCCGGCGGCTACCGGCTGCTGATCGGCCAGCAGGGCGTGAAGGTGG
AAGGCTTCGACGCCGCCGGCGTGTTCTACGGCGTGCAGACGCTGCTGGGCCTGCTGCCGCAGGGCGGCGGCCAGGTGCGC
TGGATGACGGTGGAAGATGCGCCGCGCTACGCCCACCGCGGCTTCATGGCCGACCTGGCGCGCAACTTCAAGCAGCCGGC
CACGGTGCGCCGCCTGATAGACCAGATGGCCGCCTACAAGCTCAACAAGCTGCACCTGCACCTGTCCGACGACGAGGGCT
GGCGCTTGCAGATTCCCGGACTGCCGGAGCTGACCGAGGTCGGCGCGCGCCGCTGCCACGACTTGAGCGAAACCCAGTGC
CTGGTGCCGCAGCTGGGCTCCGGGCCGGCCAACCAGTCCGGCGGCGGCTATCTCTCCCGCGCCGACTACATCGCGCTGGT
GAGCTATGCTCAGGCCCGTTTCATCGAGGTGATCCCGGAGTTCGACATGCCGGCGCACGCCCGCGCCGCGGTGGTGTCGA
TGGAGGCGCGCTACCGCAAGCTGATCGCGCAAGGCCAGCCGCAGGCGGCGTCCGAATACCGGCTGCTGGACCCGCAAGAC
CAGTCCAATACGCTGTCGGTGCAGTTCTACGACCGCCGCACCTATCTCAATCCCTGCGTGCCGGGCAGCGGCCGCTTCGT
GTCCAAGCTGGTGTCCGAGGTGGCGCAGATGCACCGAGAGGCCGGCCAGCCGCTGCAGACCTGGCACTTCGGCGGCGACG
AGGCCAAGAACATCCTGCTGGGCTCCGGCTTCCAGGACGCCAGCGGCAGCGATCCGGGCAAGGGCAAGGTCAATATGGCG
CAGCAGGACAAGCCCTGGGGCCGTTCGCCGGCCTGCCAGGCGCAGATCGCCAAGGGTAAATTGAAGAGCGTGGACGAGCT
GCCGCTGCGCTTCGCGCGCGAGGCCAGCCGCATCGTCTCCGCCCAGGGCATCCCGACGATGGCGGCCTGGCAGGACGGCG
TGGCCGGCTCCGGCGGCGCGTCCGATTTCGCCACCCGCAACACCATGGTCACCGAATGGGACACGCTGTACTGGGGCGCG
GCGCAGGCGGCCAGCGGCTACGCCGCCAAGGGCTTCAAGACCGTGCTGGCGCTGCCGGACTACCTGTACTTCGACTTCCC
CTACGAGCTGAACCCGCGCGAGCACGGCTATTACTGGGCCTCGCGCGACACCGACAGCTACAAGGTGTTCAGCTTCGCGC
CGGACAACCTGCCGCAAAACGCCGAAGTGATGCCGGACCGCCAGGGCCAGCCGTTCGCGGTGACCAGCACCGCCGCGCCG
GCGCAATACGCCGGCATCCAGGGCCAGGCCTGGACCGAGGTGATGCGCACCGACGCCGAGTTCGAAGCCATGGTCTACCC
GCGCCTGCTGGCGTTGGCCGAGCGCGCCTGGCACAAGGCGGGGTGGGAACGGCCGTACAAGGCGGGCGAAACCTATCAAC
TGGGCGTCACCAAACTGGTGGACAAGGCGGCGCTGAACGCCGACTGGCAGCAGTTCGCCGCGGTGCTGGGCTGGCGCGAG
GCGCCCAAGCTGGAGCGCGCCGGCATAGGCTACCGGGTGTCGATGCCGGCGGTGCTGCCGGGTTCCGGCGGCGTGTCGGT
GACGACCGAATGGCCAGGCGCGCGGCTGCAGTACTCGAGCGACGGCCATGGCTGGCAAACCTACCAGCCGGGCCAGCAGG
TGCAGGCGCGCTACTGGCGTGGCATCACCCAGGACGGCCGCCGCGCCGGCAGGGTGGAGACCGTGTCCGGGCAGTGA

Upstream 100 bases:

>100_bases
AATACCAATTAAATACCAATTCCGTTCGCATCGCGGGCGAGGGCGGCGGCTCGGGCAGGCAAGCCCGGAATGCCATGGTG
GATATGCAAGGGAGTGGACG

Downstream 100 bases:

>100_bases
GCGGCAGGGTGCGCGGGCAAGACGCTGGCCCGCGGTTTGAGAGCCGGACGCATCCGGTGAATGCCTGGTGTGCTTGGCAA
GAGACGGCGGGCCTGCTGGT

Product: b-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 878; Mature: 878

Protein sequence:

>878_residues
MNVKRLLGAAVLAALSAWAWAAPDAAALGQSLSLKIAVDSNKGAAAGAPCADLGADWASCLKGRLILENKGGQAVPAGGG
WNLYLHSIRRILKLDTPQFTLRHITGDLYQITPTAAFQGLAPGQKLELPLIDEYWILQESDVLPRPYVTVDGQPPALLRH
DSSDEASYLLPLSGDNWKNPAGELRPLATPEQRYRAFSLRGTQLSAAQAANRTIPAVRRQQLGGGELLVRGVSLNLSGVS
PAQQDALAGRAAQLELRAGGTRVEGGVVGAKLPADIAVPGGYRLLIGQQGVKVEGFDAAGVFYGVQTLLGLLPQGGGQVR
WMTVEDAPRYAHRGFMADLARNFKQPATVRRLIDQMAAYKLNKLHLHLSDDEGWRLQIPGLPELTEVGARRCHDLSETQC
LVPQLGSGPANQSGGGYLSRADYIALVSYAQARFIEVIPEFDMPAHARAAVVSMEARYRKLIAQGQPQAASEYRLLDPQD
QSNTLSVQFYDRRTYLNPCVPGSGRFVSKLVSEVAQMHREAGQPLQTWHFGGDEAKNILLGSGFQDASGSDPGKGKVNMA
QQDKPWGRSPACQAQIAKGKLKSVDELPLRFAREASRIVSAQGIPTMAAWQDGVAGSGGASDFATRNTMVTEWDTLYWGA
AQAASGYAAKGFKTVLALPDYLYFDFPYELNPREHGYYWASRDTDSYKVFSFAPDNLPQNAEVMPDRQGQPFAVTSTAAP
AQYAGIQGQAWTEVMRTDAEFEAMVYPRLLALAERAWHKAGWERPYKAGETYQLGVTKLVDKAALNADWQQFAAVLGWRE
APKLERAGIGYRVSMPAVLPGSGGVSVTTEWPGARLQYSSDGHGWQTYQPGQQVQARYWRGITQDGRRAGRVETVSGQ

Sequences:

>Translated_878_residues
MNVKRLLGAAVLAALSAWAWAAPDAAALGQSLSLKIAVDSNKGAAAGAPCADLGADWASCLKGRLILENKGGQAVPAGGG
WNLYLHSIRRILKLDTPQFTLRHITGDLYQITPTAAFQGLAPGQKLELPLIDEYWILQESDVLPRPYVTVDGQPPALLRH
DSSDEASYLLPLSGDNWKNPAGELRPLATPEQRYRAFSLRGTQLSAAQAANRTIPAVRRQQLGGGELLVRGVSLNLSGVS
PAQQDALAGRAAQLELRAGGTRVEGGVVGAKLPADIAVPGGYRLLIGQQGVKVEGFDAAGVFYGVQTLLGLLPQGGGQVR
WMTVEDAPRYAHRGFMADLARNFKQPATVRRLIDQMAAYKLNKLHLHLSDDEGWRLQIPGLPELTEVGARRCHDLSETQC
LVPQLGSGPANQSGGGYLSRADYIALVSYAQARFIEVIPEFDMPAHARAAVVSMEARYRKLIAQGQPQAASEYRLLDPQD
QSNTLSVQFYDRRTYLNPCVPGSGRFVSKLVSEVAQMHREAGQPLQTWHFGGDEAKNILLGSGFQDASGSDPGKGKVNMA
QQDKPWGRSPACQAQIAKGKLKSVDELPLRFAREASRIVSAQGIPTMAAWQDGVAGSGGASDFATRNTMVTEWDTLYWGA
AQAASGYAAKGFKTVLALPDYLYFDFPYELNPREHGYYWASRDTDSYKVFSFAPDNLPQNAEVMPDRQGQPFAVTSTAAP
AQYAGIQGQAWTEVMRTDAEFEAMVYPRLLALAERAWHKAGWERPYKAGETYQLGVTKLVDKAALNADWQQFAAVLGWRE
APKLERAGIGYRVSMPAVLPGSGGVSVTTEWPGARLQYSSDGHGWQTYQPGQQVQARYWRGITQDGRRAGRVETVSGQ
>Mature_878_residues
MNVKRLLGAAVLAALSAWAWAAPDAAALGQSLSLKIAVDSNKGAAAGAPCADLGADWASCLKGRLILENKGGQAVPAGGG
WNLYLHSIRRILKLDTPQFTLRHITGDLYQITPTAAFQGLAPGQKLELPLIDEYWILQESDVLPRPYVTVDGQPPALLRH
DSSDEASYLLPLSGDNWKNPAGELRPLATPEQRYRAFSLRGTQLSAAQAANRTIPAVRRQQLGGGELLVRGVSLNLSGVS
PAQQDALAGRAAQLELRAGGTRVEGGVVGAKLPADIAVPGGYRLLIGQQGVKVEGFDAAGVFYGVQTLLGLLPQGGGQVR
WMTVEDAPRYAHRGFMADLARNFKQPATVRRLIDQMAAYKLNKLHLHLSDDEGWRLQIPGLPELTEVGARRCHDLSETQC
LVPQLGSGPANQSGGGYLSRADYIALVSYAQARFIEVIPEFDMPAHARAAVVSMEARYRKLIAQGQPQAASEYRLLDPQD
QSNTLSVQFYDRRTYLNPCVPGSGRFVSKLVSEVAQMHREAGQPLQTWHFGGDEAKNILLGSGFQDASGSDPGKGKVNMA
QQDKPWGRSPACQAQIAKGKLKSVDELPLRFAREASRIVSAQGIPTMAAWQDGVAGSGGASDFATRNTMVTEWDTLYWGA
AQAASGYAAKGFKTVLALPDYLYFDFPYELNPREHGYYWASRDTDSYKVFSFAPDNLPQNAEVMPDRQGQPFAVTSTAAP
AQYAGIQGQAWTEVMRTDAEFEAMVYPRLLALAERAWHKAGWERPYKAGETYQLGVTKLVDKAALNADWQQFAAVLGWRE
APKLERAGIGYRVSMPAVLPGSGGVSVTTEWPGARLQYSSDGHGWQTYQPGQQVQARYWRGITQDGRRAGRVETVSGQ

Specific function: Digests the beta-1,4-glycosidic bonds in N- acetylglucosamine (GlcNAc) oligomers (mainly dimers) [H]

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=266, Percent_Identity=25.187969924812, Blast_Score=80, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17569815, Length=298, Percent_Identity=25.1677852348993, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17933586, Length=294, Percent_Identity=25.5102040816327, Blast_Score=81, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24657468, Length=125, Percent_Identity=32.8, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647501, Length=125, Percent_Identity=32.8, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281365639, Length=125, Percent_Identity=32.8, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24657474, Length=125, Percent_Identity=32.8, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR008965
- InterPro:   IPR004866
- InterPro:   IPR012291
- InterPro:   IPR013812
- InterPro:   IPR001540
- InterPro:   IPR004867
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR014756 [H]

Pfam domain/function: PF03173 CHB_HEX; PF03174 CHB_HEX_C; PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 95256; Mature: 95256

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKRLLGAAVLAALSAWAWAAPDAAALGQSLSLKIAVDSNKGAAAGAPCADLGADWASC
CCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHCHHHHHH
LKGRLILENKGGQAVPAGGGWNLYLHSIRRILKLDTPQFTLRHITGDLYQITPTAAFQGL
HCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCCEEEECHHHHHCCC
APGQKLELPLIDEYWILQESDVLPRPYVTVDGQPPALLRHDSSDEASYLLPLSGDNWKNP
CCCCEECCCCCCCEEEEECCCCCCCCEEEECCCCCCEEECCCCCCCEEEEEECCCCCCCC
AGELRPLATPEQRYRAFSLRGTQLSAAQAANRTIPAVRRQQLGGGELLVRGVSLNLSGVS
CCCCCCCCCHHHHHEEEEECCCEEHHHHHHCCCCHHHHHHHCCCCEEEEEEEEEEECCCC
PAQQDALAGRAAQLELRAGGTRVEGGVVGAKLPADIAVPGGYRLLIGQQGVKVEGFDAAG
CHHHHHHCCCCEEEEEECCCEEECCCEEECCCCCCEECCCCEEEEEECCCCEEECCCCHH
VFYGVQTLLGLLPQGGGQVRWMTVEDAPRYAHRGFMADLARNFKQPATVRRLIDQMAAYK
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHE
LNKLHLHLSDDEGWRLQIPGLPELTEVGARRCHDLSETQCLVPQLGSGPANQSGGGYLSR
EEEEEEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCH
ADYIALVSYAQARFIEVIPEFDMPAHARAAVVSMEARYRKLIAQGQPQAASEYRLLDPQD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCC
QSNTLSVQFYDRRTYLNPCVPGSGRFVSKLVSEVAQMHREAGQPLQTWHFGGDEAKNILL
CCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHCEEEE
GSGFQDASGSDPGKGKVNMAQQDKPWGRSPACQAQIAKGKLKSVDELPLRFAREASRIVS
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHCCHHHHHHHHHHHHHHHHH
AQGIPTMAAWQDGVAGSGGASDFATRNTMVTEWDTLYWGAAQAASGYAAKGFKTVLALPD
CCCCCCHHHHCCCCCCCCCCCCHHCCCCEEEECCHHEECCHHHCCCCCCCCHHHEEECCC
YLYFDFPYELNPREHGYYWASRDTDSYKVFSFAPDNLPQNAEVMPDRQGQPFAVTSTAAP
EEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCC
AQYAGIQGQAWTEVMRTDAEFEAMVYPRLLALAERAWHKAGWERPYKAGETYQLGVTKLV
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHH
DKAALNADWQQFAAVLGWREAPKLERAGIGYRVSMPAVLPGSGGVSVTTEWPGARLQYSS
HHHHCCCCHHHHHHHHCCCCCCCHHHCCCCEEEECCEEECCCCCEEEEECCCCCEEEECC
DGHGWQTYQPGQQVQARYWRGITQDGRRAGRVETVSGQ
CCCCCCCCCCHHHHHHHHHCCCCCCCHHCCCEEECCCC
>Mature Secondary Structure
MNVKRLLGAAVLAALSAWAWAAPDAAALGQSLSLKIAVDSNKGAAAGAPCADLGADWASC
CCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHCHHHHHH
LKGRLILENKGGQAVPAGGGWNLYLHSIRRILKLDTPQFTLRHITGDLYQITPTAAFQGL
HCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCCEEEECHHHHHCCC
APGQKLELPLIDEYWILQESDVLPRPYVTVDGQPPALLRHDSSDEASYLLPLSGDNWKNP
CCCCEECCCCCCCEEEEECCCCCCCCEEEECCCCCCEEECCCCCCCEEEEEECCCCCCCC
AGELRPLATPEQRYRAFSLRGTQLSAAQAANRTIPAVRRQQLGGGELLVRGVSLNLSGVS
CCCCCCCCCHHHHHEEEEECCCEEHHHHHHCCCCHHHHHHHCCCCEEEEEEEEEEECCCC
PAQQDALAGRAAQLELRAGGTRVEGGVVGAKLPADIAVPGGYRLLIGQQGVKVEGFDAAG
CHHHHHHCCCCEEEEEECCCEEECCCEEECCCCCCEECCCCEEEEEECCCCEEECCCCHH
VFYGVQTLLGLLPQGGGQVRWMTVEDAPRYAHRGFMADLARNFKQPATVRRLIDQMAAYK
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHE
LNKLHLHLSDDEGWRLQIPGLPELTEVGARRCHDLSETQCLVPQLGSGPANQSGGGYLSR
EEEEEEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCH
ADYIALVSYAQARFIEVIPEFDMPAHARAAVVSMEARYRKLIAQGQPQAASEYRLLDPQD
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCC
QSNTLSVQFYDRRTYLNPCVPGSGRFVSKLVSEVAQMHREAGQPLQTWHFGGDEAKNILL
CCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHCEEEE
GSGFQDASGSDPGKGKVNMAQQDKPWGRSPACQAQIAKGKLKSVDELPLRFAREASRIVS
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHCCHHHHHHHHHHHHHHHHH
AQGIPTMAAWQDGVAGSGGASDFATRNTMVTEWDTLYWGAAQAASGYAAKGFKTVLALPD
CCCCCCHHHHCCCCCCCCCCCCHHCCCCEEEECCHHEECCHHHCCCCCCCCHHHEEECCC
YLYFDFPYELNPREHGYYWASRDTDSYKVFSFAPDNLPQNAEVMPDRQGQPFAVTSTAAP
EEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCC
AQYAGIQGQAWTEVMRTDAEFEAMVYPRLLALAERAWHKAGWERPYKAGETYQLGVTKLV
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHH
DKAALNADWQQFAAVLGWREAPKLERAGIGYRVSMPAVLPGSGGVSVTTEWPGARLQYSS
HHHHCCCCHHHHHHHHCCCCCCCHHHCCCCEEEECCEEECCCCCEEEEECCCCCEEEECC
DGHGWQTYQPGQQVQARYWRGITQDGRRAGRVETVSGQ
CCCCCCCCCCHHHHHHHHHCCCCCCCHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8621090; 8673609 [H]