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The map label for this gene is ygjG [C]

Identifier: 34496891

GI number: 34496891

Start: 1518713

End: 1520053

Strand: Direct

Name: ygjG [C]

Synonym: CV_1436

Alternate gene names: 34496891

Gene position: 1518713-1520053 (Clockwise)

Preceding gene: 34496889

Following gene: 34496892

Centisome position: 31.97

GC content: 68.01

Gene sequence:

>1341_bases
ATGAACCACCCGCTCACCACCCGTTCCGAATTCGACCATCTAGACCTGCGCGCGCACTGGATGCCGTTCAGCGCCAACCG
CAATTTCCAGCGCGATCCGCGGTTGATCGTGTCCGGCGAGGGCAACTATCTGACCGACGCCGACGGCCGCCGCATCTTCG
ACAGCCTGTCCGGCCTGTGGTGTTGCGGCGCCGGCCACAGCCGCAAGGAGATCGCCGAGGCGGCCTATCGCCAGCTGTCG
ACGCTGGATTATTCGCCCGGCTTCCAGTTCGGCCACCCGTTGTCGTTCCGGCTGGCCGAGCGCGTGGCGGCGATGGCGCC
GGGCGCGCTGAACCACGTGTTCTTCACCAACTCCGGCTCCGAATGCGCGGACACCGCGGTGAAGATGGCGCGCGCCTACT
GGCGGCTGAAGGGCCAGGCGTCCAAGACCAAGCTGATCGGCCGCGCCCGCGGCTACCACGGCGTCAACATCGCCGGCACC
AGCCTGGGCGGCATGAACGGCAACCGCAAATTATTCGGCCCGCTGATGGACGCGGACCATCTGCCGCACACCTTGCTGCC
GGCCAACGCCTTCAGCCGCGGCCTGCCGGAGCAGGGCGCGGAGCTGGCGGACGATCTGCTGCGGCTGATCGAGCTGCACG
ACGCGTCCAATATCGCCGCGGTGATTGTGGAGCCGATGGCCGGCTCCGCCGGCGTGATCGTGCCGCCGCAGGGCTATCTG
CAGCGCTTGCGGGAGATTTGCACGCAGCACGGCATCCTGCTGATCTTCGACGAGGTGATCACCGGTTTCGGCCGCACCGG
CTCGCTGTTCGGCGCCGACCACTTCGGCGTGACGCCGGACATCATGAATCTGGCCAAGCAGCTGACCAATGGCGCGGTGC
CGATGGGCGCGGTGGTGGCGAGCTCGGAGATCTACGACGCTTTCATGGCACAGGCCACGCCGGAGTACGCGGTGGAATTC
GCTCATGGTTATACCTATTCGGCACACCCGGTGGCCTGCGCGGCGGCGCTGGCGGCGCTGGATGTGCTGGAGCAGGAAAA
CCTGGTGGCGAGAGCCGCGGAGCTGGCACCCCACTTCGAGCGCGGCATTCACGGCCTGAAAGGCTTGCCGCATGTGATCG
ACATCCGCAACTGCGGTCTGGCCGGCGCGGTGCAGATCGCGCCGAGCGGCGGCGACGCCATCGTGCGGCCCTACGAGGCG
GCGATGGCGCTGTGGCGCAAGGGCTTCTACGTCCGCTACGGCGGCGACGCGCTGCAGTTCGGCCCGCCGTTCACCGCCAC
GCCGCAGGAGCTGGACAGCCTGTTCGACGCTGTCGGCGAGACGCTGGCCAAGCTGGCCTGA

Upstream 100 bases:

>100_bases
ATGGTTTGATATTCACTAATCTGAACGTAAGAAAGATAGCATTTAACTCACGCAATGTCCGCGGCATGCTGTGTCTATAT
TCCTGCCAGCGAGGCTTGCG

Downstream 100 bases:

>100_bases
AACGATTGTCACCAATAAAAGAGAAACTGAAATGACGACTTTGCAGCATCTGATCCACGGCGAGGCTTGCGACGGCGGCA
GCCGCCGCGCGCCGGTTTTC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNHPLTTRSEFDHLDLRAHWMPFSANRNFQRDPRLIVSGEGNYLTDADGRRIFDSLSGLWCCGAGHSRKEIAEAAYRQLS
TLDYSPGFQFGHPLSFRLAERVAAMAPGALNHVFFTNSGSECADTAVKMARAYWRLKGQASKTKLIGRARGYHGVNIAGT
SLGGMNGNRKLFGPLMDADHLPHTLLPANAFSRGLPEQGAELADDLLRLIELHDASNIAAVIVEPMAGSAGVIVPPQGYL
QRLREICTQHGILLIFDEVITGFGRTGSLFGADHFGVTPDIMNLAKQLTNGAVPMGAVVASSEIYDAFMAQATPEYAVEF
AHGYTYSAHPVACAAALAALDVLEQENLVARAAELAPHFERGIHGLKGLPHVIDIRNCGLAGAVQIAPSGGDAIVRPYEA
AMALWRKGFYVRYGGDALQFGPPFTATPQELDSLFDAVGETLAKLA

Sequences:

>Translated_446_residues
MNHPLTTRSEFDHLDLRAHWMPFSANRNFQRDPRLIVSGEGNYLTDADGRRIFDSLSGLWCCGAGHSRKEIAEAAYRQLS
TLDYSPGFQFGHPLSFRLAERVAAMAPGALNHVFFTNSGSECADTAVKMARAYWRLKGQASKTKLIGRARGYHGVNIAGT
SLGGMNGNRKLFGPLMDADHLPHTLLPANAFSRGLPEQGAELADDLLRLIELHDASNIAAVIVEPMAGSAGVIVPPQGYL
QRLREICTQHGILLIFDEVITGFGRTGSLFGADHFGVTPDIMNLAKQLTNGAVPMGAVVASSEIYDAFMAQATPEYAVEF
AHGYTYSAHPVACAAALAALDVLEQENLVARAAELAPHFERGIHGLKGLPHVIDIRNCGLAGAVQIAPSGGDAIVRPYEA
AMALWRKGFYVRYGGDALQFGPPFTATPQELDSLFDAVGETLAKLA
>Mature_446_residues
MNHPLTTRSEFDHLDLRAHWMPFSANRNFQRDPRLIVSGEGNYLTDADGRRIFDSLSGLWCCGAGHSRKEIAEAAYRQLS
TLDYSPGFQFGHPLSFRLAERVAAMAPGALNHVFFTNSGSECADTAVKMARAYWRLKGQASKTKLIGRARGYHGVNIAGT
SLGGMNGNRKLFGPLMDADHLPHTLLPANAFSRGLPEQGAELADDLLRLIELHDASNIAAVIVEPMAGSAGVIVPPQGYL
QRLREICTQHGILLIFDEVITGFGRTGSLFGADHFGVTPDIMNLAKQLTNGAVPMGAVVASSEIYDAFMAQATPEYAVEF
AHGYTYSAHPVACAAALAALDVLEQENLVARAAELAPHFERGIHGLKGLPHVIDIRNCGLAGAVQIAPSGGDAIVRPYEA
AMALWRKGFYVRYGGDALQFGPPFTATPQELDSLFDAVGETLAKLA

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=422, Percent_Identity=31.2796208530806, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI284507298, Length=333, Percent_Identity=33.033033033033, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI37574042, Length=456, Percent_Identity=27.6315789473684, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442705, Length=456, Percent_Identity=27.4122807017544, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI13994255, Length=381, Percent_Identity=29.1338582677165, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI24119277, Length=458, Percent_Identity=27.0742358078603, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI226442709, Length=400, Percent_Identity=27.75, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=281, Percent_Identity=23.4875444839858, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI38679950, Length=281, Percent_Identity=23.4875444839858, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI38679946, Length=281, Percent_Identity=23.4875444839858, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI145693181, Length=414, Percent_Identity=31.1594202898551, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786991, Length=440, Percent_Identity=31.1363636363636, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789759, Length=446, Percent_Identity=30.2690582959641, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788044, Length=444, Percent_Identity=29.7297297297297, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789016, Length=367, Percent_Identity=29.700272479564, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=29.5238095238095, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786349, Length=347, Percent_Identity=29.3948126801153, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=451, Percent_Identity=29.2682926829268, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=424, Percent_Identity=27.3584905660377, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=463, Percent_Identity=25.0539956803456, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=234, Percent_Identity=32.4786324786325, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=23.5159817351598, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323470, Length=431, Percent_Identity=27.8422273781903, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=434, Percent_Identity=26.9585253456221, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=403, Percent_Identity=24.0694789081886, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=281, Percent_Identity=24.9110320284698, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357415, Length=423, Percent_Identity=29.0780141843972, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI28574759, Length=446, Percent_Identity=28.9237668161435, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI161085790, Length=440, Percent_Identity=27.9545454545455, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21356575, Length=394, Percent_Identity=28.9340101522843, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281366494, Length=364, Percent_Identity=22.2527472527473, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24667139, Length=364, Percent_Identity=22.2527472527473, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24667143, Length=364, Percent_Identity=22.2527472527473, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48011; Mature: 48011

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPLTTRSEFDHLDLRAHWMPFSANRNFQRDPRLIVSGEGNYLTDADGRRIFDSLSGLW
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHCCEE
CCGAGHSRKEIAEAAYRQLSTLDYSPGFQFGHPLSFRLAERVAAMAPGALNHVFFTNSGS
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
ECADTAVKMARAYWRLKGQASKTKLIGRARGYHGVNIAGTSLGGMNGNRKLFGPLMDADH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCCCCCCC
LPHTLLPANAFSRGLPEQGAELADDLLRLIELHDASNIAAVIVEPMAGSAGVIVPPQGYL
CCCHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHHHH
QRLREICTQHGILLIFDEVITGFGRTGSLFGADHFGVTPDIMNLAKQLTNGAVPMGAVVA
HHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
SSEIYDAFMAQATPEYAVEFAHGYTYSAHPVACAAALAALDVLEQENLVARAAELAPHFE
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIHGLKGLPHVIDIRNCGLAGAVQIAPSGGDAIVRPYEAAMALWRKGFYVRYGGDALQF
HHHHHHCCCCCEEEECCCCCCCEEEECCCCCCCEECHHHHHHHHHHCCCEEEECCCEEEC
GPPFTATPQELDSLFDAVGETLAKLA
CCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHPLTTRSEFDHLDLRAHWMPFSANRNFQRDPRLIVSGEGNYLTDADGRRIFDSLSGLW
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHCCEE
CCGAGHSRKEIAEAAYRQLSTLDYSPGFQFGHPLSFRLAERVAAMAPGALNHVFFTNSGS
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
ECADTAVKMARAYWRLKGQASKTKLIGRARGYHGVNIAGTSLGGMNGNRKLFGPLMDADH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEECCCCCCCC
LPHTLLPANAFSRGLPEQGAELADDLLRLIELHDASNIAAVIVEPMAGSAGVIVPPQGYL
CCCHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHHHH
QRLREICTQHGILLIFDEVITGFGRTGSLFGADHFGVTPDIMNLAKQLTNGAVPMGAVVA
HHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
SSEIYDAFMAQATPEYAVEFAHGYTYSAHPVACAAALAALDVLEQENLVARAAELAPHFE
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIHGLKGLPHVIDIRNCGLAGAVQIAPSGGDAIVRPYEAAMALWRKGFYVRYGGDALQF
HHHHHHCCCCCEEEECCCCCCCEEEECCCCCCCEECHHHHHHHHHHCCCEEEECCCEEEC
GPPFTATPQELDSLFDAVGETLAKLA
CCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]