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The map label for this gene is infC [H]

Identifier: 34496804

GI number: 34496804

Start: 1422345

End: 1422806

Strand: Direct

Name: infC [H]

Synonym: CV_1349

Alternate gene names: 34496804

Gene position: 1422345-1422806 (Clockwise)

Preceding gene: 34496803

Following gene: 34496805

Centisome position: 29.94

GC content: 57.58

Gene sequence:

>462_bases
CTGGTAGGTAAGGAAGGTGAGCAGATTGGCATCGTCAGTCTGCGTGAAGCGATGGCTCTTGCCGAAGAGAACGATGTGGA
TCTGGTGGAGATTTCCCCGACCGCTCAGCCTCCGGTGTGCAAGCTGATGGACTACGGCAAGTACAAGTACGAGCAGTCCA
AGAAGCGCCACGAAGCCAAGCAGAAGCAGAAGCAGGTTCAGATCAAGGAAATCAAGTTCCGTCCGGGTACCGACGATGGC
GACTACAACGTCAAGCTGCGCAACCTGGTTCGTTTCCTGACTGAAGGCGACAAGGCCAAGGTCACCCTGCGCTTCCGCGG
TCGTGAGATGGCTCACCAGGACATCGGCCTCGCGCTGCTCAAGCGCGTGGAGGCCGACCTGGCGGAAGTGGGCACTGTGG
AACAGTTCCCGCGACTGGAAGGCCGTCAGATGGTCATGATGATTGCGCCGAAGAAGAAATAA

Upstream 100 bases:

>100_bases
ATCCAGCGGCGGCAGACTAAACATTCATTAGGAGATTTCAGCTATAGCTCAGGAACGCGAAGCACGGATCAACGGCGAGA
TTACCGCTCGCGAGATCCGT

Downstream 100 bases:

>100_bases
TCGGTATAATCATCGTTCGACACGGCAGGGTGCGCTCTGCCGTGTTGGTTTTGTAGGTCGGCAACGATCTGCTCAAAAGC
GTGACGCAGCGGTTTCAAGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MVGKEGEQIGIVSLREAMALAEENDVDLVEISPTAQPPVCKLMDYGKYKYEQSKKRHEAKQKQKQVQIKEIKFRPGTDDG
DYNVKLRNLVRFLTEGDKAKVTLRFRGREMAHQDIGLALLKRVEADLAEVGTVEQFPRLEGRQMVMMIAPKKK

Sequences:

>Translated_153_residues
MVGKEGEQIGIVSLREAMALAEENDVDLVEISPTAQPPVCKLMDYGKYKYEQSKKRHEAKQKQKQVQIKEIKFRPGTDDG
DYNVKLRNLVRFLTEGDKAKVTLRFRGREMAHQDIGLALLKRVEADLAEVGTVEQFPRLEGRQMVMMIAPKKK
>Mature_153_residues
MVGKEGEQIGIVSLREAMALAEENDVDLVEISPTAQPPVCKLMDYGKYKYEQSKKRHEAKQKQKQVQIKEIKFRPGTDDG
DYNVKLRNLVRFLTEGDKAKVTLRFRGREMAHQDIGLALLKRVEADLAEVGTVEQFPRLEGRQMVMMIAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=154, Percent_Identity=68.8311688311688, Blast_Score=206, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17488; Mature: 17488

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGKEGEQIGIVSLREAMALAEENDVDLVEISPTAQPPVCKLMDYGKYKYEQSKKRHEAK
CCCCCCCEECHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHH
QKQKQVQIKEIKFRPGTDDGDYNVKLRNLVRFLTEGDKAKVTLRFRGREMAHQDIGLALL
HHHHHCCHHEEEECCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
KRVEADLAEVGTVEQFPRLEGRQMVMMIAPKKK
HHHHHHHHHHCCHHHCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MVGKEGEQIGIVSLREAMALAEENDVDLVEISPTAQPPVCKLMDYGKYKYEQSKKRHEAK
CCCCCCCEECHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHH
QKQKQVQIKEIKFRPGTDDGDYNVKLRNLVRFLTEGDKAKVTLRFRGREMAHQDIGLALL
HHHHHCCHHEEEECCCCCCCCCEEEHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
KRVEADLAEVGTVEQFPRLEGRQMVMMIAPKKK
HHHHHHHHHHCCHHHCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]