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The map label for this gene is hptG [H]

Identifier: 34496773

GI number: 34496773

Start: 1387793

End: 1389745

Strand: Direct

Name: hptG [H]

Synonym: CV_1318

Alternate gene names: 34496773

Gene position: 1387793-1389745 (Clockwise)

Preceding gene: 34496772

Following gene: 34496774

Centisome position: 29.21

GC content: 61.8

Gene sequence:

>1953_bases
ATGCCGGCAACAGCCGCCATCTGCCGGCTATCGCCAACCTCAATAACATTGACGACCATGAGTGCACAGAAAGAAACCCT
GGGTTTTCAGACCGAAGTCAAACAGCTGCTCAAGCTGATGATCCATTCCTTGTATTCCAACAAGGAAATCTTCTTGCGTG
AATTGATCTCCAATGCGTCCGACGCGGCCGACAAGCTGCGCTTCGAGGGCCTGGCCAAGCCGGAGCTGTTCGAGAACGAT
CCGGAGCTGAAGATCCGCATCGCCTTCGATAAAGACGCCCGCACCATCACTATCGCCGACAACGGCATCGGCATGAGCCG
CGACGAAGTGGTGTCCCATATCGGCACCATCGCCAAGTCGGGCACCAAGTCCTTCTTCGAGCAGCTGTCCGGCGACGAGA
AAAAGGATGCCCACCTGATCGGCCAGTTTGGCGTAGGCTTCTATTCCGCCTTCATCGTCGCCGACAAGGTGACGCTGACC
ACCCGTCGCGCCGGCGAGGCCGAGGCCGTGCGCTGGGAGTCGCACGGCGAGGGCGAGTACACGCTGGAGAGCGTGGAGAA
GGCCGAGCGCGGCACCGAGATCGTCCTGCACCTGAAGGAGGGCGAGGACGAGCTGCTGAACGACTGGAAGCTGAAGGGCA
TCATCCGCAAGTATTCCGACCACATCTCCATCCCGATCGAGATGAAGAAGGGCAACAGCTACGGCGAGAACGGCGAAGTG
ATCGTCAGCGACGAAATGGAGGCGGTCAACTCCGCGTCCGCGCTGTGGACCCGCTCCAAGAACGACATCAGCGAAGAGCA
GTACCAGGAATTCTACAAGCACGTCGCCCACGACTTCACCGCCCCGCTGGCCTGGAGCCACGCCCGCGTCGAGGGCCGCC
AGGAATACACCGAGCTGCTGTATATCCCGTCGCGCGCGCCGTTCGACCTGTATGACCGCGAGCGCAAGCAGGGCGTGAAG
CTGTACGTGCGCCGCGTCTTCATCATGGAAGACACCGAGAAGCTGATGCCGCACTACCTGCGCTTCGTGCGCGGCGTGAT
CGACAGCAACGATCTGCCGCTGAACGTGTCGCGCGAAATCTTGCAGGAGTCCAAGGACATCGACGCCATCCGCGCCGGCT
GCGTGAAGAAGGTGCTGGGCCTGCTGGAAGACTTGTCGGCCAACCAGCCGGAGAAGTACGCCGAGTTCTGGAAGGAATTC
GGCCAGGTGCTGAAGGAAGGCGTGGGCGAGGACTTCGCCAACAAGGAGCGCATCGCCAAGCTGCTGCGTTTCGTCTCCAC
CGCGTCCGAAGACGCCGAGCCCACCGTATCGCTGGCTGATTACATCGGCCGGATGAAGGAAGGCCAGGACAAGATCTACT
ACATCACCGCCGACACGCTGGCCGCCGCCAAGAACAGTCCGCATCTGGAAGTGTTCAAGAAGAAGGGCGTGGAGGTGCTG
CTGTTGACCGACCGCGTCGACGAATGGGTGACAGGCTCGCTGTTCGAATTCGACGGCAAGGCGCTGCAATCCGTCGCCAA
GGGCGCCCTCGATCTGGGCGCGCTGGAAGACGAGGCCGACAAGGAAGCGCAGAAGCAGGTCGAGGAAGCGTCCAAGCCGG
TGGTGGAAAAAGTGCAGAAGGCGTTGGGCGACAAGGTGAAGGAGGTGCGCGCCACCGCCCGCCTGGTGGAAAGCCCGGCT
TGCCTGGTGGCCGGCGAGCATGACATGAGCGCCCACCTGGAGCGCATGCTGAAGGCTGCCGGCCAGAAGATAGAAGGCAG
CAAGCCGACGCTGGAAATCAATCCGGAGCATGTGCTGGTCAAGCGTTTGGCCGAGGAGTCCGACGAGGCCCGCGCCGGCG
ACCTGGCCGCCGTGCTCTACGATCAGGCCTTGCTGGCCGAAGGCGGCAAGCTGGAAGACCCTGCCTCCTTCGTCAAGCGC
ATCAACAAGCTGATGCTGGAGTTGTCGGTCTGA

Upstream 100 bases:

>100_bases
CGCAGCCGCAGGACGGCCAGGCCGAATCCTGAGCCGCGCTTTCCGTTGAGGACAAAAGCCCTGTCGCCTGACAGGGCTTT
TTGCATTCCTGCCACTTGAA

Downstream 100 bases:

>100_bases
GCCTGCAGGCGCAGATTCCGCAAATGAACCGCCCTTTCCCTGGGCGGTTTTTTATTGCCGTTGTCCTAAAATGAAAGTCC
CTGCAAGCGAACCAGGAGAC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MPATAAICRLSPTSITLTTMSAQKETLGFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEGLAKPELFEND
PELKIRIAFDKDARTITIADNGIGMSRDEVVSHIGTIAKSGTKSFFEQLSGDEKKDAHLIGQFGVGFYSAFIVADKVTLT
TRRAGEAEAVRWESHGEGEYTLESVEKAERGTEIVLHLKEGEDELLNDWKLKGIIRKYSDHISIPIEMKKGNSYGENGEV
IVSDEMEAVNSASALWTRSKNDISEEQYQEFYKHVAHDFTAPLAWSHARVEGRQEYTELLYIPSRAPFDLYDRERKQGVK
LYVRRVFIMEDTEKLMPHYLRFVRGVIDSNDLPLNVSREILQESKDIDAIRAGCVKKVLGLLEDLSANQPEKYAEFWKEF
GQVLKEGVGEDFANKERIAKLLRFVSTASEDAEPTVSLADYIGRMKEGQDKIYYITADTLAAAKNSPHLEVFKKKGVEVL
LLTDRVDEWVTGSLFEFDGKALQSVAKGALDLGALEDEADKEAQKQVEEASKPVVEKVQKALGDKVKEVRATARLVESPA
CLVAGEHDMSAHLERMLKAAGQKIEGSKPTLEINPEHVLVKRLAEESDEARAGDLAAVLYDQALLAEGGKLEDPASFVKR
INKLMLELSV

Sequences:

>Translated_650_residues
MPATAAICRLSPTSITLTTMSAQKETLGFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEGLAKPELFEND
PELKIRIAFDKDARTITIADNGIGMSRDEVVSHIGTIAKSGTKSFFEQLSGDEKKDAHLIGQFGVGFYSAFIVADKVTLT
TRRAGEAEAVRWESHGEGEYTLESVEKAERGTEIVLHLKEGEDELLNDWKLKGIIRKYSDHISIPIEMKKGNSYGENGEV
IVSDEMEAVNSASALWTRSKNDISEEQYQEFYKHVAHDFTAPLAWSHARVEGRQEYTELLYIPSRAPFDLYDRERKQGVK
LYVRRVFIMEDTEKLMPHYLRFVRGVIDSNDLPLNVSREILQESKDIDAIRAGCVKKVLGLLEDLSANQPEKYAEFWKEF
GQVLKEGVGEDFANKERIAKLLRFVSTASEDAEPTVSLADYIGRMKEGQDKIYYITADTLAAAKNSPHLEVFKKKGVEVL
LLTDRVDEWVTGSLFEFDGKALQSVAKGALDLGALEDEADKEAQKQVEEASKPVVEKVQKALGDKVKEVRATARLVESPA
CLVAGEHDMSAHLERMLKAAGQKIEGSKPTLEINPEHVLVKRLAEESDEARAGDLAAVLYDQALLAEGGKLEDPASFVKR
INKLMLELSV
>Mature_649_residues
PATAAICRLSPTSITLTTMSAQKETLGFQTEVKQLLKLMIHSLYSNKEIFLRELISNASDAADKLRFEGLAKPELFENDP
ELKIRIAFDKDARTITIADNGIGMSRDEVVSHIGTIAKSGTKSFFEQLSGDEKKDAHLIGQFGVGFYSAFIVADKVTLTT
RRAGEAEAVRWESHGEGEYTLESVEKAERGTEIVLHLKEGEDELLNDWKLKGIIRKYSDHISIPIEMKKGNSYGENGEVI
VSDEMEAVNSASALWTRSKNDISEEQYQEFYKHVAHDFTAPLAWSHARVEGRQEYTELLYIPSRAPFDLYDRERKQGVKL
YVRRVFIMEDTEKLMPHYLRFVRGVIDSNDLPLNVSREILQESKDIDAIRAGCVKKVLGLLEDLSANQPEKYAEFWKEFG
QVLKEGVGEDFANKERIAKLLRFVSTASEDAEPTVSLADYIGRMKEGQDKIYYITADTLAAAKNSPHLEVFKKKGVEVLL
LTDRVDEWVTGSLFEFDGKALQSVAKGALDLGALEDEADKEAQKQVEEASKPVVEKVQKALGDKVKEVRATARLVESPAC
LVAGEHDMSAHLERMLKAAGQKIEGSKPTLEINPEHVLVKRLAEESDEARAGDLAAVLYDQALLAEGGKLEDPASFVKRI
NKLMLELSV

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=680, Percent_Identity=39.1176470588235, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI4507677, Length=691, Percent_Identity=38.205499276411, Blast_Score=436, Evalue=1e-122,
Organism=Homo sapiens, GI155722983, Length=649, Percent_Identity=36.2095531587057, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=412, Percent_Identity=40.2912621359223, Blast_Score=303, Evalue=5e-82,
Organism=Homo sapiens, GI153792590, Length=412, Percent_Identity=40.2912621359223, Blast_Score=301, Evalue=1e-81,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=60.32, Blast_Score=790, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=40.8345752608048, Blast_Score=484, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17542208, Length=666, Percent_Identity=38.2882882882883, Blast_Score=428, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI115535205, Length=649, Percent_Identity=36.055469953775, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=38.5844748858447, Blast_Score=273, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6323840, Length=675, Percent_Identity=39.7037037037037, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6325016, Length=414, Percent_Identity=41.304347826087, Blast_Score=312, Evalue=1e-85,
Organism=Drosophila melanogaster, GI21357739, Length=675, Percent_Identity=38.5185185185185, Blast_Score=423, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24586016, Length=642, Percent_Identity=37.3831775700935, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI17647529, Length=412, Percent_Identity=40.0485436893204, Blast_Score=308, Evalue=7e-84,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72634; Mature: 72503

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATAAICRLSPTSITLTTMSAQKETLGFQTEVKQLLKLMIHSLYSNKEIFLRELISNAS
CCCCHHEEEECCCEEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
DAADKLRFEGLAKPELFENDPELKIRIAFDKDARTITIADNGIGMSRDEVVSHIGTIAKS
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GTKSFFEQLSGDEKKDAHLIGQFGVGFYSAFIVADKVTLTTRRAGEAEAVRWESHGEGEY
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCCCCH
TLESVEKAERGTEIVLHLKEGEDELLNDWKLKGIIRKYSDHISIPIEMKKGNSYGENGEV
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCE
IVSDEMEAVNSASALWTRSKNDISEEQYQEFYKHVAHDFTAPLAWSHARVEGRQEYTELL
EEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHEE
YIPSRAPFDLYDRERKQGVKLYVRRVFIMEDTEKLMPHYLRFVRGVIDSNDLPLNVSREI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LQESKDIDAIRAGCVKKVLGLLEDLSANQPEKYAEFWKEFGQVLKEGVGEDFANKERIAK
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LLRFVSTASEDAEPTVSLADYIGRMKEGQDKIYYITADTLAAAKNSPHLEVFKKKGVEVL
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCHHHHHHCCCEEE
LLTDRVDEWVTGSLFEFDGKALQSVAKGALDLGALEDEADKEAQKQVEEASKPVVEKVQK
EEECCCCHHHCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALGDKVKEVRATARLVESPACLVAGEHDMSAHLERMLKAAGQKIEGSKPTLEINPEHVLV
HHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHH
KRLAEESDEARAGDLAAVLYDQALLAEGGKLEDPASFVKRINKLMLELSV
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PATAAICRLSPTSITLTTMSAQKETLGFQTEVKQLLKLMIHSLYSNKEIFLRELISNAS
CCCHHEEEECCCEEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
DAADKLRFEGLAKPELFENDPELKIRIAFDKDARTITIADNGIGMSRDEVVSHIGTIAKS
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GTKSFFEQLSGDEKKDAHLIGQFGVGFYSAFIVADKVTLTTRRAGEAEAVRWESHGEGEY
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCCCCH
TLESVEKAERGTEIVLHLKEGEDELLNDWKLKGIIRKYSDHISIPIEMKKGNSYGENGEV
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCE
IVSDEMEAVNSASALWTRSKNDISEEQYQEFYKHVAHDFTAPLAWSHARVEGRQEYTELL
EEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHEE
YIPSRAPFDLYDRERKQGVKLYVRRVFIMEDTEKLMPHYLRFVRGVIDSNDLPLNVSREI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LQESKDIDAIRAGCVKKVLGLLEDLSANQPEKYAEFWKEFGQVLKEGVGEDFANKERIAK
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LLRFVSTASEDAEPTVSLADYIGRMKEGQDKIYYITADTLAAAKNSPHLEVFKKKGVEVL
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCHHHHHHCCCEEE
LLTDRVDEWVTGSLFEFDGKALQSVAKGALDLGALEDEADKEAQKQVEEASKPVVEKVQK
EEECCCCHHHCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALGDKVKEVRATARLVESPACLVAGEHDMSAHLERMLKAAGQKIEGSKPTLEINPEHVLV
HHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHH
KRLAEESDEARAGDLAAVLYDQALLAEGGKLEDPASFVKRINKLMLELSV
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]