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The map label for this gene is nrdR

Identifier: 34496742

GI number: 34496742

Start: 1354805

End: 1355263

Strand: Direct

Name: nrdR

Synonym: CV_1287

Alternate gene names: 34496742

Gene position: 1354805-1355263 (Clockwise)

Preceding gene: 34496741

Following gene: 34496743

Centisome position: 28.52

GC content: 62.96

Gene sequence:

>459_bases
ATGAAATGCGCGTTTTGTGGCAACCCGGACACCCAGGTGATCGATTCCCGCGTCAGCGAGGACGGCAGCAGCATCCGCCG
CCGCCGCCGCTGCCCGGCCTGCGACAAGCGTTTCACGACCTTCGAAACCGCCGATGTGCGCATGCCGCAGGTGGTGAAGA
CCGCCGGACACCGTTCCGAGTTCGACATCGAGAAAGTGCGCACCAGCTTCCTGCGCGCGCTGCACAAGCGGCCGGTGTCC
ACCACGCTGGTGGACGAGGCGATAGACCGCATCTGCCACAAGCTGCTGCAGCTGGGCGAGCGCGAGGTCAGCAGCCGCCA
GATCGGCGAGATGGTGATGAACGAGCTGGCGCGGCTGGACAAGGTGGCTTATGTGCGTTTCGCGTCGGTTTACCGCAGCT
TCCAGGATATTTCCGAGTTCACCGACGCGATCAAGGAAATCCAGAAGTCCTCGCATTGA

Upstream 100 bases:

>100_bases
CTTTTTCTTTGCGCCAGGCCAGGCTTCGTCCATGGCCGGCGGTGCGGGCGGGCGGCATTGCTGATAACATCCAACTATTG
CAACCCACAGGATTATTGTC

Downstream 100 bases:

>100_bases
CGGCGGCATGGCCGCTTGATTAGCCTTGGTGATTCAATTGTCATTTTGCGAGACACCATGAGCGCCATCGTCCAGAAACG
CATCGTCCTGCTGCCGCCCG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKCAFCGNPDTQVIDSRVSEDGSSIRRRRRCPACDKRFTTFETADVRMPQVVKTAGHRSEFDIEKVRTSFLRALHKRPVS
TTLVDEAIDRICHKLLQLGEREVSSRQIGEMVMNELARLDKVAYVRFASVYRSFQDISEFTDAIKEIQKSSH

Sequences:

>Translated_152_residues
MKCAFCGNPDTQVIDSRVSEDGSSIRRRRRCPACDKRFTTFETADVRMPQVVKTAGHRSEFDIEKVRTSFLRALHKRPVS
TTLVDEAIDRICHKLLQLGEREVSSRQIGEMVMNELARLDKVAYVRFASVYRSFQDISEFTDAIKEIQKSSH
>Mature_152_residues
MKCAFCGNPDTQVIDSRVSEDGSSIRRRRRCPACDKRFTTFETADVRMPQVVKTAGHRSEFDIEKVRTSFLRALHKRPVS
TTLVDEAIDRICHKLLQLGEREVSSRQIGEMVMNELARLDKVAYVRFASVYRSFQDISEFTDAIKEIQKSSH

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=55.4054054054054, Blast_Score=166, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_CHRVO (Q7NYI7)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900957.1
- GeneID:   2551026
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1287
- NMPDR:   fig|243365.1.peg.1287
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q7NYI7
- ProtClustDB:   PRK00464
- BioCyc:   CVIO243365:CV_1287-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17485; Mature: 17485

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCAFCGNPDTQVIDSRVSEDGSSIRRRRRCPACDKRFTTFETADVRMPQVVKTAGHRSE
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHCCCCCHHHCHHHHHHHHHCCCCH
FDIEKVRTSFLRALHKRPVSTTLVDEAIDRICHKLLQLGEREVSSRQIGEMVMNELARLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVAYVRFASVYRSFQDISEFTDAIKEIQKSSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCAFCGNPDTQVIDSRVSEDGSSIRRRRRCPACDKRFTTFETADVRMPQVVKTAGHRSE
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHCCCCCHHHCHHHHHHHHHCCCCH
FDIEKVRTSFLRALHKRPVSTTLVDEAIDRICHKLLQLGEREVSSRQIGEMVMNELARLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVAYVRFASVYRSFQDISEFTDAIKEIQKSSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782