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The map label for this gene is mtaD [H]

Identifier: 34496487

GI number: 34496487

Start: 1075739

End: 1077058

Strand: Reverse

Name: mtaD [H]

Synonym: CV_1032

Alternate gene names: 34496487

Gene position: 1077058-1075739 (Counterclockwise)

Preceding gene: 34496490

Following gene: 34496486

Centisome position: 22.67

GC content: 66.21

Gene sequence:

>1320_bases
ATGCCGCAGTCCCGTTATGAAAAGATTATCTCCGCCCGCTGGATCATCACCGTGGAAACTGACGGCGAAGTCCTGGAAAA
CCACGCGATCGCCATTCGGGACGGCAAGATAGCCGCCATTATTCCAGCAGCCGACGCCGCCGGGCTAGAGGCGGATGAAA
GGCTGGAGCTGCCCGACCATGTGCTGATGCCCGGCCTGATCAACCTGCACGGCCACTCCGCGATGTCGCTGCTGCGCGGC
CTGGCCGACGACAAGGCGCTGATGGACTGGCTGACCAATTACATCTGGCCCACCGAAGGCAAGCACGTCCACGACGACTT
CGTGTTCGACGGCTCGCTGCTGGCGATGGGCGAAATGATCCGCGGCGGCACCACCACCATCAACGACATGTATTTCTATA
ATGCCGCCGTCGCCCGCGCCGGCCTGGCTTCCGGCATGCGCACCTTCGTCGGCTGTTCCATCCTGGAATTCCCGACCAAT
TACGCGTCCAACGCCGATGACTACATCGCCAAGGGCATGGCCGAGCGCAGCCAGTTCCTGGGGGAAGACCTGCTGACCTT
CACGCTGGCGCCGCACGCGCCCTACACCGTATCGGACGATACCTTCCGCAAGGTTGTGACGCTGGCCGAGCAGGAGGACA
TGCTGATCCACTGCCACATCCACGAAACCGCGGACGAGGTGAACAACAGCGTCAAGGAGCACGGCCAGCGCCCGCTGGCC
CGCCTGCAGCGGCTGGGCCTGCTGTCCCCGCGCCTGGTGGCGGCGCACATGGTGCACCTGAACGACGCCGAAGTCGAACT
GGCGGCCAGGCACGGCCTGTCCACCGCGCACAACCCCGCCTCGAACATGAAGCTGGCTTCGGGCATCTCGCCGGTGAGCA
AGCTGATGGACGCCGGCGTCGCCGTGGGCATCGGCACCGACGGCGCCGCGTCCAACAACAAGCTGGACATGCTGGCGGAA
ACCCGCCTGGCCGCGCTGCTGGCCAAGGTGGGCACCCTGGACCCGACCTCGGTGCCGGCCGCCGCCGCCATCCGCATGGC
CACGCTGAACGGCGCGCGCGCGCTGGGCATCGCCGACAAGGTCGGCTCGGTCAAGGTGGGCAAGCAGGCCGACCTGATCG
CCCTCGACCTGGCCCAACTGGAAACCGCGCCGGCATTCGACCCGATCTCCCATGTGGTGTACGCTGCCGGTCGCGAACAG
GTCAGCCACGTCTGGGTCAAGGGCCGCGCGCTGATGCGCGAGCGCAAGCTGACCACGCTGGACGAAAGCGACCTGAAGGC
CCGCGCCGGCGACTGGCGCAACCGCATTCTGGCAAAGTGA

Upstream 100 bases:

>100_bases
CGGTGAAATATAAAGAGAGCACAGCAGCTCATTGCCTTGCCGCAATCGCAGGGCCTAAAATCCACGACACTTAAGACAAC
GGATCATCAGGATATCAGCC

Downstream 100 bases:

>100_bases
TAGCATGAGCAACGTAGACGAACTCGAAATCGACAAATTCAGCCAGCTGGCGCACAAGTGGTGGGACAAGGACAGCGAAT
TCAAGCCGCTGCACGAGATC

Product: N-ethylammeline chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MPQSRYEKIISARWIITVETDGEVLENHAIAIRDGKIAAIIPAADAAGLEADERLELPDHVLMPGLINLHGHSAMSLLRG
LADDKALMDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMIRGGTTTINDMYFYNAAVARAGLASGMRTFVGCSILEFPTN
YASNADDYIAKGMAERSQFLGEDLLTFTLAPHAPYTVSDDTFRKVVTLAEQEDMLIHCHIHETADEVNNSVKEHGQRPLA
RLQRLGLLSPRLVAAHMVHLNDAEVELAARHGLSTAHNPASNMKLASGISPVSKLMDAGVAVGIGTDGAASNNKLDMLAE
TRLAALLAKVGTLDPTSVPAAAAIRMATLNGARALGIADKVGSVKVGKQADLIALDLAQLETAPAFDPISHVVYAAGREQ
VSHVWVKGRALMRERKLTTLDESDLKARAGDWRNRILAK

Sequences:

>Translated_439_residues
MPQSRYEKIISARWIITVETDGEVLENHAIAIRDGKIAAIIPAADAAGLEADERLELPDHVLMPGLINLHGHSAMSLLRG
LADDKALMDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMIRGGTTTINDMYFYNAAVARAGLASGMRTFVGCSILEFPTN
YASNADDYIAKGMAERSQFLGEDLLTFTLAPHAPYTVSDDTFRKVVTLAEQEDMLIHCHIHETADEVNNSVKEHGQRPLA
RLQRLGLLSPRLVAAHMVHLNDAEVELAARHGLSTAHNPASNMKLASGISPVSKLMDAGVAVGIGTDGAASNNKLDMLAE
TRLAALLAKVGTLDPTSVPAAAAIRMATLNGARALGIADKVGSVKVGKQADLIALDLAQLETAPAFDPISHVVYAAGREQ
VSHVWVKGRALMRERKLTTLDESDLKARAGDWRNRILAK
>Mature_438_residues
PQSRYEKIISARWIITVETDGEVLENHAIAIRDGKIAAIIPAADAAGLEADERLELPDHVLMPGLINLHGHSAMSLLRGL
ADDKALMDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMIRGGTTTINDMYFYNAAVARAGLASGMRTFVGCSILEFPTNY
ASNADDYIAKGMAERSQFLGEDLLTFTLAPHAPYTVSDDTFRKVVTLAEQEDMLIHCHIHETADEVNNSVKEHGQRPLAR
LQRLGLLSPRLVAAHMVHLNDAEVELAARHGLSTAHNPASNMKLASGISPVSKLMDAGVAVGIGTDGAASNNKLDMLAET
RLAALLAKVGTLDPTSVPAAAAIRMATLNGARALGIADKVGSVKVGKQADLIALDLAQLETAPAFDPISHVVYAAGREQV
SHVWVKGRALMRERKLTTLDESDLKARAGDWRNRILAK

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=378, Percent_Identity=26.984126984127, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1789249, Length=401, Percent_Identity=26.1845386533666, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082177, Length=440, Percent_Identity=24.3181818181818, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17540282, Length=428, Percent_Identity=24.7663551401869, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319963, Length=331, Percent_Identity=24.4712990936556, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24643849, Length=435, Percent_Identity=26.4367816091954, Blast_Score=134, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 47382; Mature: 47251

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSRYEKIISARWIITVETDGEVLENHAIAIRDGKIAAIIPAADAAGLEADERLELPDH
CCHHHHHHHHHEEEEEEEECCCHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCH
VLMPGLINLHGHSAMSLLRGLADDKALMDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMI
HHCCCCEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCEEECCHHHHHHHHH
RGGTTTINDMYFYNAAVARAGLASGMRTFVGCSILEFPTNYASNADDYIAKGMAERSQFL
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCHHHHHHHHHHHHHHH
GEDLLTFTLAPHAPYTVSDDTFRKVVTLAEQEDMLIHCHIHETADEVNNSVKEHGQRPLA
HCHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHH
RLQRLGLLSPRLVAAHMVHLNDAEVELAARHGLSTAHNPASNMKLASGISPVSKLMDAGV
HHHHCCCCCCHHHHHHHEECCCCHHHHHHHCCCCCCCCCHHCCCHHCCCCHHHHHHHCCE
AVGIGTDGAASNNKLDMLAETRLAALLAKVGTLDPTSVPAAAAIRMATLNGARALGIADK
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEECCCCEEECCHHC
VGSVKVGKQADLIALDLAQLETAPAFDPISHVVYAAGREQVSHVWVKGRALMRERKLTTL
CCCEECCCCCCEEEEEHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
DESDLKARAGDWRNRILAK
CCHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
PQSRYEKIISARWIITVETDGEVLENHAIAIRDGKIAAIIPAADAAGLEADERLELPDH
CHHHHHHHHHEEEEEEEECCCHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCH
VLMPGLINLHGHSAMSLLRGLADDKALMDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMI
HHCCCCEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCCEEECCHHHHHHHHH
RGGTTTINDMYFYNAAVARAGLASGMRTFVGCSILEFPTNYASNADDYIAKGMAERSQFL
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCHHHHHHHHHHHHHHH
GEDLLTFTLAPHAPYTVSDDTFRKVVTLAEQEDMLIHCHIHETADEVNNSVKEHGQRPLA
HCHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCHHH
RLQRLGLLSPRLVAAHMVHLNDAEVELAARHGLSTAHNPASNMKLASGISPVSKLMDAGV
HHHHCCCCCCHHHHHHHEECCCCHHHHHHHCCCCCCCCCHHCCCHHCCCCHHHHHHHCCE
AVGIGTDGAASNNKLDMLAETRLAALLAKVGTLDPTSVPAAAAIRMATLNGARALGIADK
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEECCCCEEECCHHC
VGSVKVGKQADLIALDLAQLETAPAFDPISHVVYAAGREQVSHVWVKGRALMRERKLTTL
CCCEECCCCCCEEEEEHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
DESDLKARAGDWRNRILAK
CCHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA