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The map label for this gene is ubiG

Identifier: 34496486

GI number: 34496486

Start: 1075036

End: 1075734

Strand: Reverse

Name: ubiG

Synonym: CV_1031

Alternate gene names: 34496486

Gene position: 1075734-1075036 (Counterclockwise)

Preceding gene: 34496487

Following gene: 34496485

Centisome position: 22.64

GC content: 65.24

Gene sequence:

>699_bases
ATGAGCAACGTAGACGAACTCGAAATCGACAAATTCAGCCAGCTGGCGCACAAGTGGTGGGACAAGGACAGCGAATTCAA
GCCGCTGCACGAGATCAACCCGCTGCGCCTGGACTTCATCGACCGCCACGCGTCCATCGCCGGCAAGAAGGTGCTGGACG
TCGGCTGCGGCGGCGGCATCCTGGCCGAGAGCATGGCGCTGAGAGGCGCGCAGGTGACCGGCATCGACCTGGCTAAAAAA
TCGCTGAAGGTGGCGCAGCTGCACAGCCTGGAGTCCGGCGTGCCCATCGACTACCGCTGCGTGGCGGTGGAGGATCTGGC
GGCCGAAATGCCGGGCGCCTTCGATGCGGTGACCTGCATGGAGATGCTGGAACACGTGCCGGACCCGGAAAGCGTGGTGC
GCGCCTGCTCCACGCTGGTGAAGCCGGGCGGCTGGGTGTTCTTCTCCACGCTGAACCGCAACGCCAAGGCCTATCTGCTG
GCCGTGGTCGGTGCCGAATACGTGTTGAACATGCTGCCGCGCGGCACCCATGAATACGCGCGTTTTCTGAAGCCGTCGGA
GCTGGGCCGCATGGCCCGCCACGCCGGCCTCGGCCTGCAGACGCTGAGCGGCATGGGCTACAACCCCGTCACCCGCATCT
ACTCGCTGAACGACGACACCGCCGTCAACTACCTGATGGCGACCCGCCGCGCCGACTGA

Upstream 100 bases:

>100_bases
CGCGCGCTGATGCGCGAGCGCAAGCTGACCACGCTGGACGAAAGCGACCTGAAGGCCCGCGCCGGCGACTGGCGCAACCG
CATTCTGGCAAAGTGATAGC

Downstream 100 bases:

>100_bases
GCCCCCCGCCCCGGCCCCGCGCGCCTTGCGGACCGCCCGGCCGGGGAAGGAAGGTCTCCCGGCGGCTGCCCTGCCCATGA
GGCCCGGCCATGCCGGGCCT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSNVDELEIDKFSQLAHKWWDKDSEFKPLHEINPLRLDFIDRHASIAGKKVLDVGCGGGILAESMALRGAQVTGIDLAKK
SLKVAQLHSLESGVPIDYRCVAVEDLAAEMPGAFDAVTCMEMLEHVPDPESVVRACSTLVKPGGWVFFSTLNRNAKAYLL
AVVGAEYVLNMLPRGTHEYARFLKPSELGRMARHAGLGLQTLSGMGYNPVTRIYSLNDDTAVNYLMATRRAD

Sequences:

>Translated_232_residues
MSNVDELEIDKFSQLAHKWWDKDSEFKPLHEINPLRLDFIDRHASIAGKKVLDVGCGGGILAESMALRGAQVTGIDLAKK
SLKVAQLHSLESGVPIDYRCVAVEDLAAEMPGAFDAVTCMEMLEHVPDPESVVRACSTLVKPGGWVFFSTLNRNAKAYLL
AVVGAEYVLNMLPRGTHEYARFLKPSELGRMARHAGLGLQTLSGMGYNPVTRIYSLNDDTAVNYLMATRRAD
>Mature_231_residues
SNVDELEIDKFSQLAHKWWDKDSEFKPLHEINPLRLDFIDRHASIAGKKVLDVGCGGGILAESMALRGAQVTGIDLAKKS
LKVAQLHSLESGVPIDYRCVAVEDLAAEMPGAFDAVTCMEMLEHVPDPESVVRACSTLVKPGGWVFFSTLNRNAKAYLLA
VVGAEYVLNMLPRGTHEYARFLKPSELGRMARHAGLGLQTLSGMGYNPVTRIYSLNDDTAVNYLMATRRAD

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=237, Percent_Identity=37.1308016877637, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1788564, Length=228, Percent_Identity=57.8947368421053, Blast_Score=277, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI115533050, Length=235, Percent_Identity=31.063829787234, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324476, Length=283, Percent_Identity=31.095406360424, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24585589, Length=234, Percent_Identity=31.6239316239316, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI281365311, Length=245, Percent_Identity=30.6122448979592, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_CHRVO (Q7NZ91)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900701.1
- ProteinModelPortal:   Q7NZ91
- SMR:   Q7NZ91
- GeneID:   2551055
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1031
- NMPDR:   fig|243365.1.peg.1031
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   Q7NZ91
- ProtClustDB:   PRK05134
- BioCyc:   CVIO243365:CV_1031-MONOMER
- BRENDA:   2.1.1.64
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 25508; Mature: 25376

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVDELEIDKFSQLAHKWWDKDSEFKPLHEINPLRLDFIDRHASIAGKKVLDVGCGGGI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCEEEECCCCHH
LAESMALRGAQVTGIDLAKKSLKVAQLHSLESGVPIDYRCVAVEDLAAEMPGAFDAVTCM
HHHHHHHCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHH
EMLEHVPDPESVVRACSTLVKPGGWVFFSTLNRNAKAYLLAVVGAEYVLNMLPRGTHEYA
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHCCCCHHHHH
RFLKPSELGRMARHAGLGLQTLSGMGYNPVTRIYSLNDDTAVNYLMATRRAD
HHCCHHHHHHHHHHHCCCHHHHCCCCCCCHHEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SNVDELEIDKFSQLAHKWWDKDSEFKPLHEINPLRLDFIDRHASIAGKKVLDVGCGGGI
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCEEEECCCCHH
LAESMALRGAQVTGIDLAKKSLKVAQLHSLESGVPIDYRCVAVEDLAAEMPGAFDAVTCM
HHHHHHHCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHH
EMLEHVPDPESVVRACSTLVKPGGWVFFSTLNRNAKAYLLAVVGAEYVLNMLPRGTHEYA
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHCCCCHHHHH
RFLKPSELGRMARHAGLGLQTLSGMGYNPVTRIYSLNDDTAVNYLMATRRAD
HHCCHHHHHHHHHHHCCCHHHHCCCCCCCHHEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782