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The map label for this gene is yeaB [H]

Identifier: 34496460

GI number: 34496460

Start: 1043985

End: 1044926

Strand: Reverse

Name: yeaB [H]

Synonym: CV_1005

Alternate gene names: 34496460

Gene position: 1044926-1043985 (Counterclockwise)

Preceding gene: 34496461

Following gene: 34496459

Centisome position: 21.99

GC content: 69.0

Gene sequence:

>942_bases
ATGATGAGCCACCACCACACGCCTCTCAGCGACGAGACCGACAGCGCCGAACGCCGGCAGGCCGCGCGCCGCAGCACGCT
GGTCAGCGTCGCCGTCAACATCGTGCTGTCCACGCTGCAGATCGTGGCCGGCGCGTGGTCGCACTCGTCGGCGCTGATCG
CCGACGGCGTGCACTCCTTGTCCGACCTGTTCGCCGACTTCGTGGTCCTGCTGGCCGGACGCCACAGCGGCAAGGAGCCG
GACGACGATCACCATTACGGCCATCAGCGCTACGAAAACGCCGCGTCGCTGGTTCTCGGGCTGCTGCTGCTGGCGGTCGG
CGGCGGCATGCTGTACTCGGCGGCAGCCAAGTTCCTGCATCCTGAAGACATTCCTTCGGTGCACTCGCTGGCATTGTGGA
TCGCCGCGCTGGCGCTGCTGGCCAAGGAGACGCTGTTCCGCTACATGCTGGCGGTAGCGCAGCGCGTGCGCTCCAGCATG
CTGGTGGCCAACGCCTGGCACGCGCGCTCCGACGCGGCTTCCTCGCTGGTGGTCGCCGCCGGCGTGGCCGGCAACCTGAT
GGGCTATCCGATACTGGATCCGGTGGCGGCGCTGGTGGTCGGCCTGCTGGTGGGCAAGATGGGCTGGCGCTTCGCCTGGG
ACGCGCTGCACGACCTGATGGACCGCGCCGCCAGCGAAGAGGACATCGCCGCCATCCGCGACACGCTGCTGGCCACGCCC
GGCATCGTCGGCATCCACGATCTGCGCACCCGCAAGATGGGCGACCTGATCCTGGTGGACGTGCATCTGGAAGTGGACGG
CCTCATCAATGTCTACCAGGCGCACGAGATCACCGAGCATGCCCGCGGCCGGGTGCTCAGCGCGCTGCCGGTGCTGGACG
TGATGACCCACATCGACCCGGCGGGGCAGGAAGAGCCGCGCCGCCTGCGCCGCGCCGTCTGA

Upstream 100 bases:

>100_bases
CTCGTTATCGTTTTCATTATCATTTACTTTATAAATCAAAATTTAATGACCGATAGCAAAAACGATGCGAAAATAGAAAG
ATGATCAGCCGAACCGAATC

Downstream 100 bases:

>100_bases
GCCGCCTCTCCCGGGCCGCGGCCCAGCCAATGATCATCAGGACAGTCTTTCCGGCAACTTTTTCGCCGCCGGTATGGTCT
ATCCCCTCCATGATCCCATC

Product: cation efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MMSHHHTPLSDETDSAERRQAARRSTLVSVAVNIVLSTLQIVAGAWSHSSALIADGVHSLSDLFADFVVLLAGRHSGKEP
DDDHHYGHQRYENAASLVLGLLLLAVGGGMLYSAAAKFLHPEDIPSVHSLALWIAALALLAKETLFRYMLAVAQRVRSSM
LVANAWHARSDAASSLVVAAGVAGNLMGYPILDPVAALVVGLLVGKMGWRFAWDALHDLMDRAASEEDIAAIRDTLLATP
GIVGIHDLRTRKMGDLILVDVHLEVDGLINVYQAHEITEHARGRVLSALPVLDVMTHIDPAGQEEPRRLRRAV

Sequences:

>Translated_313_residues
MMSHHHTPLSDETDSAERRQAARRSTLVSVAVNIVLSTLQIVAGAWSHSSALIADGVHSLSDLFADFVVLLAGRHSGKEP
DDDHHYGHQRYENAASLVLGLLLLAVGGGMLYSAAAKFLHPEDIPSVHSLALWIAALALLAKETLFRYMLAVAQRVRSSM
LVANAWHARSDAASSLVVAAGVAGNLMGYPILDPVAALVVGLLVGKMGWRFAWDALHDLMDRAASEEDIAAIRDTLLATP
GIVGIHDLRTRKMGDLILVDVHLEVDGLINVYQAHEITEHARGRVLSALPVLDVMTHIDPAGQEEPRRLRRAV
>Mature_313_residues
MMSHHHTPLSDETDSAERRQAARRSTLVSVAVNIVLSTLQIVAGAWSHSSALIADGVHSLSDLFADFVVLLAGRHSGKEP
DDDHHYGHQRYENAASLVLGLLLLAVGGGMLYSAAAKFLHPEDIPSVHSLALWIAALALLAKETLFRYMLAVAQRVRSSM
LVANAWHARSDAASSLVVAAGVAGNLMGYPILDPVAALVVGLLVGKMGWRFAWDALHDLMDRAASEEDIAAIRDTLLATP
GIVGIHDLRTRKMGDLILVDVHLEVDGLINVYQAHEITEHARGRVLSALPVLDVMTHIDPAGQEEPRRLRRAV

Specific function: Unknown

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family [H]

Homologues:

Organism=Homo sapiens, GI57164948, Length=261, Percent_Identity=22.9885057471264, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1790349, Length=277, Percent_Identity=26.7148014440433, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI115534117, Length=258, Percent_Identity=22.4806201550388, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325032, Length=235, Percent_Identity=29.7872340425532, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323831, Length=249, Percent_Identity=28.5140562248996, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24653143, Length=274, Percent_Identity=25.5474452554745, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653141, Length=274, Percent_Identity=25.5474452554745, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 33834; Mature: 33834

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHCC
>Mature Secondary Structure
MMSHHHTPLSDETDSAERRQAARRSTLVSVAVNIVLSTLQIVAGAWSHSSALIADGVHSL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SDLFADFVVLLAGRHSGKEPDDDHHYGHQRYENAASLVLGLLLLAVGGGMLYSAAAKFLH
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
PEDIPSVHSLALWIAALALLAKETLFRYMLAVAQRVRSSMLVANAWHARSDAASSLVVAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAGNLMGYPILDPVAALVVGLLVGKMGWRFAWDALHDLMDRAASEEDIAAIRDTLLATP
HHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
GIVGIHDLRTRKMGDLILVDVHLEVDGLINVYQAHEITEHARGRVLSALPVLDVMTHIDP
CCCCHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGQEEPRRLRRAV
CCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 8951816 [H]