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The map label for this gene is yfmJ [H]

Identifier: 34496263

GI number: 34496263

Start: 833053

End: 834045

Strand: Reverse

Name: yfmJ [H]

Synonym: CV_0808

Alternate gene names: 34496263

Gene position: 834045-833053 (Counterclockwise)

Preceding gene: 34496264

Following gene: 34496256

Centisome position: 17.55

GC content: 61.83

Gene sequence:

>993_bases
ATGAAGAGTTTGGAAATCCATCTGATCCGCCGCCCGACTGGCATGCCCAGCGCCGATCTATTCGCGCTCGAAGAAGTGGC
GCTCCCCAAGCTGCAAACCGGCCAGGCGCTTATTGAAAACCTGTACTTATCCGTCGACCCCTATATGCGGGAATGCATGG
ATTTGGAAGAGGAATGGCCATTGCACACGCCGCTGGAAGGCCGCAGCATAGGCCGCGTCATCGATGCCGGCAGCAGCGGT
TTGAATGTGGGGGAGCTGGTTTTCCATCGCGAAGGTTGGCGTAGCCATGCGGCGGTGGCGGCGGAGGAGCTGCGGGTACT
GAAAGAATACCCCGGCGTCTCCGCCAGCGCCTTCCTGAGCATCATGGGGGGCACCGGACTGACCGCCTATGTGGCGCTTA
GCCGCATCGCCAAGCTGCAGGCCGGCGAAGATATCTTCGTCTCGGCGGCCGCTGGCGGCGTCGGAAGCGCGATCGCGCAG
TTGGCCAGGCTGATGGGGGCCGGCCGCCTGATCGGCAGCACCGGCTCTGCCGCCAAGGCCCGCTACCTGACGGAAACGCT
GGACTATGATTTTGCCATTGACTACCACAGCCAAGACCTGTCCCAGGCCCTGGGCGAGGCCGCTCCGGAAGGATTCGACA
TCTATATCGATAATGTCGGCGGCAAGCACCAGGAGGCGGCGATCCGGCATATCCGCGATCATGGCCGCATCGCCTGGGTA
GGCGCGGTGGGCCAATATAACCATGCGGAGTCGCCCGAACTGGCGCGCAATCTCTACGACATCGTGGGGAAAAGCCTGCG
GCTGGAGGGTTTTTTGGTGCGCAACTACCGCCACCTGCAAGACGAATTGGAGGCTTTTGTCGTTCCCCATCTGCAGTCGG
GCCGGCTGCAGCCGCAACAGACCGTTAGAGAAGGGCTGGAGAATATGGCGCAAGCCTTCGTCGACATGCTGGCCGGGGCC
AATCTGGGCAAGATGCTGATCAAGCTCGCCTAA

Upstream 100 bases:

>100_bases
CGACCCGCGCGCTCGCGGCAGGGAAACCATCGCAGACAGATCGAGAGTCAGTCACTTTTATGATAATGTGATATTTCCTT
GAAATTTGAAAGCTGACCGC

Downstream 100 bases:

>100_bases
TGCGAAGCGCCGCGCCTCGCTTCCGGTTTTGGAGCGCGGCGCGGCGCTAGCCTTGGCGCCATGCGGCGCCCGTTTTCACA
CCCGGGTGTCGATCACCGGC

Product: zinc-containing alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKSLEIHLIRRPTGMPSADLFALEEVALPKLQTGQALIENLYLSVDPYMRECMDLEEEWPLHTPLEGRSIGRVIDAGSSG
LNVGELVFHREGWRSHAAVAAEELRVLKEYPGVSASAFLSIMGGTGLTAYVALSRIAKLQAGEDIFVSAAAGGVGSAIAQ
LARLMGAGRLIGSTGSAAKARYLTETLDYDFAIDYHSQDLSQALGEAAPEGFDIYIDNVGGKHQEAAIRHIRDHGRIAWV
GAVGQYNHAESPELARNLYDIVGKSLRLEGFLVRNYRHLQDELEAFVVPHLQSGRLQPQQTVREGLENMAQAFVDMLAGA
NLGKMLIKLA

Sequences:

>Translated_330_residues
MKSLEIHLIRRPTGMPSADLFALEEVALPKLQTGQALIENLYLSVDPYMRECMDLEEEWPLHTPLEGRSIGRVIDAGSSG
LNVGELVFHREGWRSHAAVAAEELRVLKEYPGVSASAFLSIMGGTGLTAYVALSRIAKLQAGEDIFVSAAAGGVGSAIAQ
LARLMGAGRLIGSTGSAAKARYLTETLDYDFAIDYHSQDLSQALGEAAPEGFDIYIDNVGGKHQEAAIRHIRDHGRIAWV
GAVGQYNHAESPELARNLYDIVGKSLRLEGFLVRNYRHLQDELEAFVVPHLQSGRLQPQQTVREGLENMAQAFVDMLAGA
NLGKMLIKLA
>Mature_330_residues
MKSLEIHLIRRPTGMPSADLFALEEVALPKLQTGQALIENLYLSVDPYMRECMDLEEEWPLHTPLEGRSIGRVIDAGSSG
LNVGELVFHREGWRSHAAVAAEELRVLKEYPGVSASAFLSIMGGTGLTAYVALSRIAKLQAGEDIFVSAAAGGVGSAIAQ
LARLMGAGRLIGSTGSAAKARYLTETLDYDFAIDYHSQDLSQALGEAAPEGFDIYIDNVGGKHQEAAIRHIRDHGRIAWV
GAVGQYNHAESPELARNLYDIVGKSLRLEGFLVRNYRHLQDELEAFVVPHLQSGRLQPQQTVREGLENMAQAFVDMLAGA
NLGKMLIKLA

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=335, Percent_Identity=33.4328358208955, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI226059133, Length=335, Percent_Identity=33.4328358208955, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI226246682, Length=343, Percent_Identity=32.3615160349854, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI226246680, Length=343, Percent_Identity=32.3615160349854, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI22748929, Length=343, Percent_Identity=32.3615160349854, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI226056130, Length=278, Percent_Identity=33.0935251798561, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI28557745, Length=324, Percent_Identity=26.5432098765432, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI18379349, Length=288, Percent_Identity=26.3888888888889, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI226510941, Length=335, Percent_Identity=32.8358208955224, Blast_Score=188, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI133901712, Length=346, Percent_Identity=31.5028901734104, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI133901710, Length=346, Percent_Identity=31.5028901734104, Blast_Score=154, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6323504, Length=330, Percent_Identity=26.969696969697, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35888; Mature: 35888

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLEIHLIRRPTGMPSADLFALEEVALPKLQTGQALIENLYLSVDPYMRECMDLEEEWP
CCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHCCC
LHTPLEGRSIGRVIDAGSSGLNVGELVFHREGWRSHAAVAAEELRVLKEYPGVSASAFLS
CCCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
IMGGTGLTAYVALSRIAKLQAGEDIFVSAAAGGVGSAIAQLARLMGAGRLIGSTGSAAKA
HHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEECCCCCHHHH
RYLTETLDYDFAIDYHSQDLSQALGEAAPEGFDIYIDNVGGKHQEAAIRHIRDHGRIAWV
HHHHHHCCCCEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEE
GAVGQYNHAESPELARNLYDIVGKSLRLEGFLVRNYRHLQDELEAFVVPHLQSGRLQPQQ
ECCCCCCCCCCHHHHHHHHHHHCCHHEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
TVREGLENMAQAFVDMLAGANLGKMLIKLA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MKSLEIHLIRRPTGMPSADLFALEEVALPKLQTGQALIENLYLSVDPYMRECMDLEEEWP
CCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHCCC
LHTPLEGRSIGRVIDAGSSGLNVGELVFHREGWRSHAAVAAEELRVLKEYPGVSASAFLS
CCCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
IMGGTGLTAYVALSRIAKLQAGEDIFVSAAAGGVGSAIAQLARLMGAGRLIGSTGSAAKA
HHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEECCCCCHHHH
RYLTETLDYDFAIDYHSQDLSQALGEAAPEGFDIYIDNVGGKHQEAAIRHIRDHGRIAWV
HHHHHHCCCCEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEE
GAVGQYNHAESPELARNLYDIVGKSLRLEGFLVRNYRHLQDELEAFVVPHLQSGRLQPQQ
ECCCCCCCCCCHHHHHHHHHHHCCHHEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
TVREGLENMAQAFVDMLAGANLGKMLIKLA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]