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The map label for this gene is metX

Identifier: 34496241

GI number: 34496241

Start: 810660

End: 811802

Strand: Reverse

Name: metX

Synonym: CV_0786

Alternate gene names: 34496241

Gene position: 811802-810660 (Counterclockwise)

Preceding gene: 34496247

Following gene: 34496240

Centisome position: 17.09

GC content: 67.45

Gene sequence:

>1143_bases
ATGACCGACACCAACTGTTCGGTAGGCATCGTCGCGGCCCAGGATGCCGCGTTCGACATTCCCCTGCCGCTCGCCAGCGG
CGCCGCGCTGCCGGGCTATCAGCTGCGTTTCGAGACCTACGGCAAACTCAACGCCGACAAGAGCAACGCCATCCTGATCT
GCCACGCATTGTCCGGCCACCACCATGTCGCCGGCTATTACCGCGCCGACGACAAGACCCCGGGCTGGTGGGACAATATG
ATCGGCCCCGGCAAGCCGATCGACACCCGCCGCTTCTTCGTGGTCGGCGTCAACAACCTGGGCGGTTGCCACGGCAGCAC
CGGCCCGTCCAGCGTCAACCCGGCCACCGGCCAGCCGTGGGGCTCGGCCTTTCCGGTGATGACGGTGCCGGACTGGGTGA
CCTCGCAGGCGCGCCTGGCCGACCGGCTCGGCATTGAACGCTGGGCGGCGGTGATAGGCGGCTCGCTGGGCGGCATGCAG
GCGCTGCACTGGAGCATCGCCTATCCGGAACGCGTCGCGCACGCGCTGGTGATCGCCTCCGCGCCCAAGCTGTCGGCGCA
GAACATCGCCTTCAACGACGTCGCGCGCCAGGCCATCCTCACCGACCCGGACTTTTGCGGCGGCGACTTCTACCAGCAGG
GCACCATCCCCCGCCGCGGCCTCAGGCTGGCGCGGATGCTGGGCCACATCACCTATCTGTCCGACGATGGCATGGGCGAG
AAATTCGGCCGCATGCTGCGCTCGGGGGAATACCGCTTCGGCTACGACGTGGAGTTCGAGATCGAGAGCTACCTGCGCTA
CCAAGGCGACAAGTTCTCCGATTACTTCGACGCCAACACCTATCTGCTGATGACCAAGGCGCTGGACTACTTCGACCCCG
CCGCCGCGCACGGCGGCGACCTGGCCGCCGCGCTGAAGCCGGCGCAGGCGGCGTTCATGGTGGCCAGCTTCACCAGCGAC
TGGCGCTTCTCGCCGGAGCGCTCGCGCGAGACGGTGAAGGCGCTGATCGCCGCCGGCAAGCGCGTCAGCTACGCCGAGAT
CGAGTCGGTGCACGGCCACGACGCCTTCCTGATGACCGACCAACCGTATGTGGACCTGATGCGCGCCTACCTGGACCGCG
TGGCCAAGGAGGTGAACGCATGA

Upstream 100 bases:

>100_bases
TATGTTATGGATATAATCGACCGGTAGCCGCAGGAGACCGCATCCAGACCAGCCCCGGCAGAGGGCGGCGGACGCGGACA
AATAGAAGAGGCAAGCACCC

Downstream 100 bases:

>100_bases
ACGCCATCCAGACTCTCCGCTCCGACCTCAGGCTGATCGCCGACTGGATCGCCCCGCACAGCCGGGTGCTGGACCTGGGC
TGCGGCGACGGCAGGCTGCT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTDTNCSVGIVAAQDAAFDIPLPLASGAALPGYQLRFETYGKLNADKSNAILICHALSGHHHVAGYYRADDKTPGWWDNM
IGPGKPIDTRRFFVVGVNNLGGCHGSTGPSSVNPATGQPWGSAFPVMTVPDWVTSQARLADRLGIERWAAVIGGSLGGMQ
ALHWSIAYPERVAHALVIASAPKLSAQNIAFNDVARQAILTDPDFCGGDFYQQGTIPRRGLRLARMLGHITYLSDDGMGE
KFGRMLRSGEYRFGYDVEFEIESYLRYQGDKFSDYFDANTYLLMTKALDYFDPAAAHGGDLAAALKPAQAAFMVASFTSD
WRFSPERSRETVKALIAAGKRVSYAEIESVHGHDAFLMTDQPYVDLMRAYLDRVAKEVNA

Sequences:

>Translated_380_residues
MTDTNCSVGIVAAQDAAFDIPLPLASGAALPGYQLRFETYGKLNADKSNAILICHALSGHHHVAGYYRADDKTPGWWDNM
IGPGKPIDTRRFFVVGVNNLGGCHGSTGPSSVNPATGQPWGSAFPVMTVPDWVTSQARLADRLGIERWAAVIGGSLGGMQ
ALHWSIAYPERVAHALVIASAPKLSAQNIAFNDVARQAILTDPDFCGGDFYQQGTIPRRGLRLARMLGHITYLSDDGMGE
KFGRMLRSGEYRFGYDVEFEIESYLRYQGDKFSDYFDANTYLLMTKALDYFDPAAAHGGDLAAALKPAQAAFMVASFTSD
WRFSPERSRETVKALIAAGKRVSYAEIESVHGHDAFLMTDQPYVDLMRAYLDRVAKEVNA
>Mature_379_residues
TDTNCSVGIVAAQDAAFDIPLPLASGAALPGYQLRFETYGKLNADKSNAILICHALSGHHHVAGYYRADDKTPGWWDNMI
GPGKPIDTRRFFVVGVNNLGGCHGSTGPSSVNPATGQPWGSAFPVMTVPDWVTSQARLADRLGIERWAAVIGGSLGGMQA
LHWSIAYPERVAHALVIASAPKLSAQNIAFNDVARQAILTDPDFCGGDFYQQGTIPRRGLRLARMLGHITYLSDDGMGEK
FGRMLRSGEYRFGYDVEFEIESYLRYQGDKFSDYFDANTYLLMTKALDYFDPAAAHGGDLAAALKPAQAAFMVASFTSDW
RFSPERSRETVKALIAAGKRVSYAEIESVHGHDAFLMTDQPYVDLMRAYLDRVAKEVNA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=245, Percent_Identity=33.469387755102, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_CHRVO (Q7NZY3)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900456.1
- ProteinModelPortal:   Q7NZY3
- GeneID:   2549681
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_0786
- NMPDR:   fig|243365.1.peg.786
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q7NZY3
- ProtClustDB:   PRK00175
- BioCyc:   CVIO243365:CV_0786-MONOMER
- BRENDA:   2.3.1.31
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41536; Mature: 41405

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: ACT_SITE 155-155 ACT_SITE 353-353

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTNCSVGIVAAQDAAFDIPLPLASGAALPGYQLRFETYGKLNADKSNAILICHALSGH
CCCCCCCEEEEEECCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCC
HHVAGYYRADDKTPGWWDNMIGPGKPIDTRRFFVVGVNNLGGCHGSTGPSSVNPATGQPW
CEEEEEEECCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GSAFPVMTVPDWVTSQARLADRLGIERWAAVIGGSLGGMQALHWSIAYPERVAHALVIAS
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCHHHHHHHHEEEC
APKLSAQNIAFNDVARQAILTDPDFCGGDFYQQGTIPRRGLRLARMLGHITYLSDDGMGE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHEEEECCCCCCH
KFGRMLRSGEYRFGYDVEFEIESYLRYQGDKFSDYFDANTYLLMTKALDYFDPAAAHGGD
HHHHHHHCCCCEECCEEEEEHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCC
LAAALKPAQAAFMVASFTSDWRFSPERSRETVKALIAAGKRVSYAEIESVHGHDAFLMTD
HHHHHCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEC
QPYVDLMRAYLDRVAKEVNA
CCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDTNCSVGIVAAQDAAFDIPLPLASGAALPGYQLRFETYGKLNADKSNAILICHALSGH
CCCCCCEEEEEECCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCC
HHVAGYYRADDKTPGWWDNMIGPGKPIDTRRFFVVGVNNLGGCHGSTGPSSVNPATGQPW
CEEEEEEECCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GSAFPVMTVPDWVTSQARLADRLGIERWAAVIGGSLGGMQALHWSIAYPERVAHALVIAS
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCHHHHHHHHEEEC
APKLSAQNIAFNDVARQAILTDPDFCGGDFYQQGTIPRRGLRLARMLGHITYLSDDGMGE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHEEEECCCCCCH
KFGRMLRSGEYRFGYDVEFEIESYLRYQGDKFSDYFDANTYLLMTKALDYFDPAAAHGGD
HHHHHHHCCCCEECCEEEEEHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCC
LAAALKPAQAAFMVASFTSDWRFSPERSRETVKALIAAGKRVSYAEIESVHGHDAFLMTD
HHHHHCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEC
QPYVDLMRAYLDRVAKEVNA
CCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782