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The map label for this gene is dapC [H]

Identifier: 34495906

GI number: 34495906

Start: 467896

End: 469101

Strand: Reverse

Name: dapC [H]

Synonym: CV_0451

Alternate gene names: 34495906

Gene position: 469101-467896 (Counterclockwise)

Preceding gene: 34495909

Following gene: 34495905

Centisome position: 9.87

GC content: 70.4

Gene sequence:

>1206_bases
TTGAATCCCCGCCTGGACCAATTGCATCCCTACCCGTTCCAGCGCCTGGCGGCGCTGCTGGCAGACGCCAAGCCGCCGGC
GTCGCTGCCGCACATCAGCCTGGCGATGGGCGAGCCCAAGCATCCGGCGCCGCAACTGGTGAAGGACGCGCTGTGCGCCA
ATCTCGCCGGCCTGTCCGGCTATCCGGCCACCCAGGGCACGCCGGCGCTGCGCCAAGCCTGCGCCGACTGGGCCGAACGC
CGCTACGGCGTGCGTCTGGACCCGGCGAGCGAGGTGCTGCCGGTCAACGGCAGCCGCGAGGCGCTGTTCTCGCTGACCCA
GTGCCTGATCGACGCCGGCGGCGCGGCCAAACCGGTGGTGGTGTCTCCCAATCCCTTTTACCAGATTTACGAGGGCGCGG
CACTGCTGGCCGGCGCCGAGCCCCATTACCTGAACTGCGAGGCGGAGAACCGCTTCCAGCCGGACTGGGACGGCGTGCCG
GATGAGGTGTGGCGGCGCGCCCAGCTGGTGATCGTGTGCAGCCCCGGCAACCCCACCGGCGCGGTGATGGACCTGGCCGC
CTGGGACAAGCTGTTCGCGCTGTCGGACCGCTACGGCTTCGTCATCGCCAGCGACGAATGCTATTCCGAAATCTACTTCG
ACCAGCCGCCGCTGGGCGGCCTGTCCGCCGCGCGCGCGCTCGGCCGCGGCCTCGAGCGCCTGGTGATGCTGACCAGCCTG
TCCAAACGCTCCAACGTGCCCGGCATGCGCTCCGGCTTCGTCGCCGGCGACGCGGCCATCCTGAAACAATTCCTGCTCTA
CCGCACCTACCACGGCAGCGCGATGAGCCTGACGGTGCAAGCCGCCAGCGTCGCCGCCTGGAACGACGAGGCCCACGTCG
AGTCCAACCGGGCCGCCTACGCCGCCAAGTTCGCCGCCGTGCTGCCGCTGCTGCAGCCGGTTCTCGAGGTGGAGAGGCCG
GAAGCCGGCTTCTACCTGTGGGCGAAGGTGCCGGACGGCGACGACGCGGCCTTCGCCCGCGCGCTGTTCCAGCAGCGGCA
CGTGACGGTGCTGCCAGGCAGCTATCTGGCCCGCGACGCCCACGGCGCCAATCCCGGCCGCGGCTATGTGCGCATCGCGC
TGGTGGCGGAACAGGCGGAATGCGTGGCCGCCGCGCAAAGGATTGTAGAATTCACCCAGACCCAGCGCGCCGCGACGCCG
GCGTAA

Upstream 100 bases:

>100_bases
TGAGGATGCCGGAGGTGGCGACGATTTTTTGTTTTACAGGTGTCATGGCTGTTCTTAAGATGGTCGATTGCCCGTGCCGA
ATTTCGATGGAGACGCCGCT

Downstream 100 bases:

>100_bases
GCACCCGCCACAGGATCCAGAATTACCAATGACGACTTCGATTCACATTGCCAAAGGACTGAACCAGATGCATCCGATCC
AGAGCCTGATCGAACAGGCA

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNPRLDQLHPYPFQRLAALLADAKPPASLPHISLAMGEPKHPAPQLVKDALCANLAGLSGYPATQGTPALRQACADWAER
RYGVRLDPASEVLPVNGSREALFSLTQCLIDAGGAAKPVVVSPNPFYQIYEGAALLAGAEPHYLNCEAENRFQPDWDGVP
DEVWRRAQLVIVCSPGNPTGAVMDLAAWDKLFALSDRYGFVIASDECYSEIYFDQPPLGGLSAARALGRGLERLVMLTSL
SKRSNVPGMRSGFVAGDAAILKQFLLYRTYHGSAMSLTVQAASVAAWNDEAHVESNRAAYAAKFAAVLPLLQPVLEVERP
EAGFYLWAKVPDGDDAAFARALFQQRHVTVLPGSYLARDAHGANPGRGYVRIALVAEQAECVAAAQRIVEFTQTQRAATP
A

Sequences:

>Translated_401_residues
MNPRLDQLHPYPFQRLAALLADAKPPASLPHISLAMGEPKHPAPQLVKDALCANLAGLSGYPATQGTPALRQACADWAER
RYGVRLDPASEVLPVNGSREALFSLTQCLIDAGGAAKPVVVSPNPFYQIYEGAALLAGAEPHYLNCEAENRFQPDWDGVP
DEVWRRAQLVIVCSPGNPTGAVMDLAAWDKLFALSDRYGFVIASDECYSEIYFDQPPLGGLSAARALGRGLERLVMLTSL
SKRSNVPGMRSGFVAGDAAILKQFLLYRTYHGSAMSLTVQAASVAAWNDEAHVESNRAAYAAKFAAVLPLLQPVLEVERP
EAGFYLWAKVPDGDDAAFARALFQQRHVTVLPGSYLARDAHGANPGRGYVRIALVAEQAECVAAAQRIVEFTQTQRAATP
A
>Mature_401_residues
MNPRLDQLHPYPFQRLAALLADAKPPASLPHISLAMGEPKHPAPQLVKDALCANLAGLSGYPATQGTPALRQACADWAER
RYGVRLDPASEVLPVNGSREALFSLTQCLIDAGGAAKPVVVSPNPFYQIYEGAALLAGAEPHYLNCEAENRFQPDWDGVP
DEVWRRAQLVIVCSPGNPTGAVMDLAAWDKLFALSDRYGFVIASDECYSEIYFDQPPLGGLSAARALGRGLERLVMLTSL
SKRSNVPGMRSGFVAGDAAILKQFLLYRTYHGSAMSLTVQAASVAAWNDEAHVESNRAAYAAKFAAVLPLLQPVLEVERP
EAGFYLWAKVPDGDDAAFARALFQQRHVTVLPGSYLARDAHGANPGRGYVRIALVAEQAECVAAAQRIVEFTQTQRAATP
A

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=24, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=24, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI95147551, Length=401, Percent_Identity=21.9451371571072, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI169881279, Length=401, Percent_Identity=21.9451371571072, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=28.5353535353535, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1786816, Length=395, Percent_Identity=25.0632911392405, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788627, Length=228, Percent_Identity=25, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=400, Percent_Identity=22.25, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=400, Percent_Identity=22.25, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=179, Percent_Identity=29.608938547486, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI18859735, Length=394, Percent_Identity=25.1269035532995, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573069, Length=432, Percent_Identity=22.4537037037037, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646114, Length=432, Percent_Identity=22.4537037037037, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28573067, Length=432, Percent_Identity=22.4537037037037, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28573065, Length=432, Percent_Identity=22.4537037037037, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43222; Mature: 43222

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRLDQLHPYPFQRLAALLADAKPPASLPHISLAMGEPKHPAPQLVKDALCANLAGLSG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
YPATQGTPALRQACADWAERRYGVRLDPASEVLPVNGSREALFSLTQCLIDAGGAAKPVV
CCCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEE
VSPNPFYQIYEGAALLAGAEPHYLNCEAENRFQPDWDGVPDEVWRRAQLVIVCSPGNPTG
ECCCCCEEHHCCEEEEECCCCCEEECCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCC
AVMDLAAWDKLFALSDRYGFVIASDECYSEIYFDQPPLGGLSAARALGRGLERLVMLTSL
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SKRSNVPGMRSGFVAGDAAILKQFLLYRTYHGSAMSLTVQAASVAAWNDEAHVESNRAAY
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHCCCCCHHH
AAKFAAVLPLLQPVLEVERPEAGFYLWAKVPDGDDAAFARALFQQRHVTVLPGSYLARDA
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHCCC
HGANPGRGYVRIALVAEQAECVAAAQRIVEFTQTQRAATPA
CCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNPRLDQLHPYPFQRLAALLADAKPPASLPHISLAMGEPKHPAPQLVKDALCANLAGLSG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
YPATQGTPALRQACADWAERRYGVRLDPASEVLPVNGSREALFSLTQCLIDAGGAAKPVV
CCCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCEE
VSPNPFYQIYEGAALLAGAEPHYLNCEAENRFQPDWDGVPDEVWRRAQLVIVCSPGNPTG
ECCCCCEEHHCCEEEEECCCCCEEECCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCC
AVMDLAAWDKLFALSDRYGFVIASDECYSEIYFDQPPLGGLSAARALGRGLERLVMLTSL
HHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SKRSNVPGMRSGFVAGDAAILKQFLLYRTYHGSAMSLTVQAASVAAWNDEAHVESNRAAY
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHCCCCCHHH
AAKFAAVLPLLQPVLEVERPEAGFYLWAKVPDGDDAAFARALFQQRHVTVLPGSYLARDA
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHCCC
HGANPGRGYVRIALVAEQAECVAAAQRIVEFTQTQRAATPA
CCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA