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The map label for this gene is dapD

Identifier: 34495905

GI number: 34495905

Start: 467007

End: 467828

Strand: Reverse

Name: dapD

Synonym: CV_0450

Alternate gene names: 34495905

Gene position: 467828-467007 (Counterclockwise)

Preceding gene: 34495906

Following gene: 34495904

Centisome position: 9.85

GC content: 64.36

Gene sequence:

>822_bases
ATGCATCCGATCCAGAGCCTGATCGAACAGGCATTCGAAAACCGCGCAGAGATCACCCCCGCCACCGTATCGCCGGAGCT
GAAGGCGGCCATCGAGCAGGTGATAACCGAGCTGGACAACGGCCACCTGCGCGTCGCCGAGAAAAACGGCGCGGAATGGG
TGGTCAACCAGTGGGTGAAGAAGGCGGTGCTGCTGTCCTTCCGCATCCGCGACAACGCGGTGCAGGACGACGGCGTCAAC
CGCTACTTCGACAAGGTGGACACCAAGTTCGCCGACTGGAGCCAGGCCCGCTTCCAGGAAGCCGGCTTCCGCGTGGTGCC
GGGCGCGGTGGCGCGCAAGGGCAGCTTCATCGCCAAGAACACCGTGCTGATGCCGTCCTACGTCAACATCGGCGCCTACG
TCGACGAAGGCACCATGGTGGATACCTGGGCCACCGTCGGCTCCTGCGCCCAGATCGGCAAAAATGTTCACCTGTCCGGC
GGCGTCGGCATCGGCGGCGTGCTGGAGCCGCTGCAGGCCAATCCGACCATCATCGAGGACAACTGCTTCATCGGCGCGCG
TTCGGAAATCGTCGAGGGCGTGATCGTCGGCGAGGGCTCGGTGATCTCGATGGGCGTCTACATCGGCCAGTCCACCAAGA
TCTACGACCGAGAAACCGGCGAGGTGATGTATGGCCGCGTGCCGCCGGGCTCGGTGGTGGTGTCCGGCAACCTGCCGTCC
AAGGACGGCAGCCACAGCCTGTACTGCGCCGTCATCGTCAAGAAGGTGGACGCGCAAACCCGCAGCAAGACCAGCATCAA
CGAACTGCTGCGCGGCGTGTGA

Upstream 100 bases:

>100_bases
ACCCAGACCCAGCGCGCCGCGACGCCGGCGTAAGCACCCGCCACAGGATCCAGAATTACCAATGACGACTTCGATTCACA
TTGCCAAAGGACTGAACCAG

Downstream 100 bases:

>100_bases
CATCGTCGGGGGCGCCCTCCCGGCGCCCCTCGCCGGCCGCGGACCGATCGCCGTTCGCGGCCGGTGTGCCATTATGGCAA
CACCTCTGCCCATCTTGTCA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MHPIQSLIEQAFENRAEITPATVSPELKAAIEQVITELDNGHLRVAEKNGAEWVVNQWVKKAVLLSFRIRDNAVQDDGVN
RYFDKVDTKFADWSQARFQEAGFRVVPGAVARKGSFIAKNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVGEGSVISMGVYIGQSTKIYDRETGEVMYGRVPPGSVVVSGNLPS
KDGSHSLYCAVIVKKVDAQTRSKTSINELLRGV

Sequences:

>Translated_273_residues
MHPIQSLIEQAFENRAEITPATVSPELKAAIEQVITELDNGHLRVAEKNGAEWVVNQWVKKAVLLSFRIRDNAVQDDGVN
RYFDKVDTKFADWSQARFQEAGFRVVPGAVARKGSFIAKNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVGEGSVISMGVYIGQSTKIYDRETGEVMYGRVPPGSVVVSGNLPS
KDGSHSLYCAVIVKKVDAQTRSKTSINELLRGV
>Mature_273_residues
MHPIQSLIEQAFENRAEITPATVSPELKAAIEQVITELDNGHLRVAEKNGAEWVVNQWVKKAVLLSFRIRDNAVQDDGVN
RYFDKVDTKFADWSQARFQEAGFRVVPGAVARKGSFIAKNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVGEGSVISMGVYIGQSTKIYDRETGEVMYGRVPPGSVVVSGNLPS
KDGSHSLYCAVIVKKVDAQTRSKTSINELLRGV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=273, Percent_Identity=76.9230769230769, Blast_Score=409, Evalue=1e-116,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_CHRVO (Q7P0W5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900120.1
- ProteinModelPortal:   Q7P0W5
- SMR:   Q7P0W5
- GeneID:   2550737
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_0450
- NMPDR:   fig|243365.1.peg.450
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   Q7P0W5
- ProtClustDB:   PRK11830
- BioCyc:   CVIO243365:CV_0450-MONOMER
- BRENDA:   2.3.1.117
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29496; Mature: 29496

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 104-104 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPIQSLIEQAFENRAEITPATVSPELKAAIEQVITELDNGHLRVAEKNGAEWVVNQWVK
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
KAVLLSFRIRDNAVQDDGVNRYFDKVDTKFADWSQARFQEAGFRVVPGAVARKGSFIAKN
HHHHHHEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCEECCHHHHHCCCEEECC
TVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIED
EEECCCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEEC
NCFIGARSEIVEGVIVGEGSVISMGVYIGQSTKIYDRETGEVMYGRVPPGSVVVSGNLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEEECCCCCCEEEECCCCC
KDGSHSLYCAVIVKKVDAQTRSKTSINELLRGV
CCCCCCEEEEEEEHHHCCHHCCHHHHHHHHHCC
>Mature Secondary Structure
MHPIQSLIEQAFENRAEITPATVSPELKAAIEQVITELDNGHLRVAEKNGAEWVVNQWVK
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
KAVLLSFRIRDNAVQDDGVNRYFDKVDTKFADWSQARFQEAGFRVVPGAVARKGSFIAKN
HHHHHHEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCEECCHHHHHCCCEEECC
TVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIED
EEECCCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEEC
NCFIGARSEIVEGVIVGEGSVISMGVYIGQSTKIYDRETGEVMYGRVPPGSVVVSGNLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEEECCCCCCEEEECCCCC
KDGSHSLYCAVIVKKVDAQTRSKTSINELLRGV
CCCCCCEEEEEEEHHHCCHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782