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The map label for this gene is hprK

Identifier: 161594050

GI number: 161594050

Start: 3632483

End: 3633439

Strand: Direct

Name: hprK

Synonym: CV_3335

Alternate gene names: 161594050

Gene position: 3632483-3633439 (Clockwise)

Preceding gene: 34498789

Following gene: 34498791

Centisome position: 76.46

GC content: 63.95

Gene sequence:

>957_bases
ATGCCTAGCATCACCGTGCGCCGGCTGTATCAGGAAAACCAGCAGAAACTGAATCTCACCTGGGTCGCCGGCACCGGCGG
CTCCGACAATGTGATTGGCAACGACGACCAGCGTCCTACGCTGGCCCTGGTCGGCCACCTGAACTTCATCCACCCCAACC
GGGTGCAGGTGCTGGGCCTCGCCGAGGTGGACTACCTGAACAAGCTGGAGCAGTCGGCGGCCAAGACCGCGCTGGACCAG
CTGTTCCACAAGAGCATGTCGGTGGTGATGGTGGCCAACGGCCAGCCCGTGCCCCGGCTGCTGCGCGACTACTGCCACAG
CCACAACGTGCCCTTGATGTGCAGCACGCTGGAAAGCCCGTACCTGATGGACGTGCTGCGGATTTACCTGGCGCGGGCGC
TGGCGGTGTCCACGGTGCTGCACGGCGTGTTCCTCGACGTGTTCGAGATCGGCGTGCTGATCATGGGCGACTCGGCGATG
GGCAAGAGCGAACTGGCGCTGGAGCTGATTTCCCGCGGCCACGGCATGGTGGCCGACGACGCGGTGGAGCTGTACCGCAT
CGGCCCGGACACGCTGGAGGGCCGTTGCCCGCCGCTGCTGCGCGACTTTCTGGAAGTGCGCGGCCTCGGCATCCTCAACA
TCCGCACCATCTTCGGCGAGACCGCGGTCCGTCCCAAGAAAGTGCTGAAGCTGATCATCCACTTGGTCAAGGCCAACGAC
CAGGCGATGCAGGCGCTGGACCGGCTCAACATCCAGTCCGAAACCCAGGACATCATCGGCGTCACCGTGCGCAAGGTGGT
GCTGCCGGTGGCCGCAGGCCGCAACCTGGCGGTGCTGGTGGAAGCCGCGGTGCGCAATTACATCCTGCAGCTGCGCGGCA
TAGACAGCACCCGCGAGTTCATCGAACGCCATACCAACTTCTTGAGAGACCAGGAAAATGCGCCTGATATTGATTAG

Upstream 100 bases:

>100_bases
GAGCTGGCGCAGATGTTCTCCAGCCGCCAGATGCGCGAGCAGATGCTGGGCGTGGACGCGCGCGACGACCTGTACCAGCT
GCTTTGCGAATGGACCCCCC

Downstream 100 bases:

>100_bases
CGGCCTGTCCGGCTCCGGCAAGTCGGTGGCGCTGCGCGCGCTGGAGGACTCCGGCTTCTATTGCGTGGACAATCTGCCGG
CCACCATGCTGCCCGAGGCG

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPSITVRRLYQENQQKLNLTWVAGTGGSDNVIGNDDQRPTLALVGHLNFIHPNRVQVLGLAEVDYLNKLEQSAAKTALDQ
LFHKSMSVVMVANGQPVPRLLRDYCHSHNVPLMCSTLESPYLMDVLRIYLARALAVSTVLHGVFLDVFEIGVLIMGDSAM
GKSELALELISRGHGMVADDAVELYRIGPDTLEGRCPPLLRDFLEVRGLGILNIRTIFGETAVRPKKVLKLIIHLVKAND
QAMQALDRLNIQSETQDIIGVTVRKVVLPVAAGRNLAVLVEAAVRNYILQLRGIDSTREFIERHTNFLRDQENAPDID

Sequences:

>Translated_318_residues
MPSITVRRLYQENQQKLNLTWVAGTGGSDNVIGNDDQRPTLALVGHLNFIHPNRVQVLGLAEVDYLNKLEQSAAKTALDQ
LFHKSMSVVMVANGQPVPRLLRDYCHSHNVPLMCSTLESPYLMDVLRIYLARALAVSTVLHGVFLDVFEIGVLIMGDSAM
GKSELALELISRGHGMVADDAVELYRIGPDTLEGRCPPLLRDFLEVRGLGILNIRTIFGETAVRPKKVLKLIIHLVKAND
QAMQALDRLNIQSETQDIIGVTVRKVVLPVAAGRNLAVLVEAAVRNYILQLRGIDSTREFIERHTNFLRDQENAPDID
>Mature_317_residues
PSITVRRLYQENQQKLNLTWVAGTGGSDNVIGNDDQRPTLALVGHLNFIHPNRVQVLGLAEVDYLNKLEQSAAKTALDQL
FHKSMSVVMVANGQPVPRLLRDYCHSHNVPLMCSTLESPYLMDVLRIYLARALAVSTVLHGVFLDVFEIGVLIMGDSAMG
KSELALELISRGHGMVADDAVELYRIGPDTLEGRCPPLLRDFLEVRGLGILNIRTIFGETAVRPKKVLKLIIHLVKANDQ
AMQALDRLNIQSETQDIIGVTVRKVVLPVAAGRNLAVLVEAAVRNYILQLRGIDSTREFIERHTNFLRDQENAPDID

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_CHRVO (Q7NST5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903005.2
- ProteinModelPortal:   Q7NST5
- SMR:   Q7NST5
- GeneID:   2548438
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3335
- NMPDR:   fig|243365.1.peg.3335
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   CVIO243365:CV_3335-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 35326; Mature: 35194

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: ACT_SITE 141-141 ACT_SITE 162-162 ACT_SITE 180-180 ACT_SITE 248-248

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSITVRRLYQENQQKLNLTWVAGTGGSDNVIGNDDQRPTLALVGHLNFIHPNRVQVLGL
CCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEE
AEVDYLNKLEQSAAKTALDQLFHKSMSVVMVANGQPVPRLLRDYCHSHNVPLMCSTLESP
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCH
YLMDVLRIYLARALAVSTVLHGVFLDVFEIGVLIMGDSAMGKSELALELISRGHGMVADD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCCCCCCHH
AVELYRIGPDTLEGRCPPLLRDFLEVRGLGILNIRTIFGETAVRPKKVLKLIIHLVKAND
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHCCH
QAMQALDRLNIQSETQDIIGVTVRKVVLPVAAGRNLAVLVEAAVRNYILQLRGIDSTREF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
IERHTNFLRDQENAPDID
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PSITVRRLYQENQQKLNLTWVAGTGGSDNVIGNDDQRPTLALVGHLNFIHPNRVQVLGL
CCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEE
AEVDYLNKLEQSAAKTALDQLFHKSMSVVMVANGQPVPRLLRDYCHSHNVPLMCSTLESP
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCH
YLMDVLRIYLARALAVSTVLHGVFLDVFEIGVLIMGDSAMGKSELALELISRGHGMVADD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCCCCCCHH
AVELYRIGPDTLEGRCPPLLRDFLEVRGLGILNIRTIFGETAVRPKKVLKLIIHLVKAND
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHCCH
QAMQALDRLNIQSETQDIIGVTVRKVVLPVAAGRNLAVLVEAAVRNYILQLRGIDSTREF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
IERHTNFLRDQENAPDID
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782