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The map label for this gene is thrC [H]

Identifier: 33864538

GI number: 33864538

Start: 2409528

End: 2410637

Strand: Direct

Name: thrC [H]

Synonym: PMT2274

Alternate gene names: 33864538

Gene position: 2409528-2410637 (Clockwise)

Preceding gene: 33864537

Following gene: NA

Centisome position: 99.94

GC content: 45.5

Gene sequence:

>1110_bases
TTGGTGTCCCTCAGCCAAAACCTCCCTCAAGCTATCTCCACAACGCCTGTGATGCAGGATTGGCCTGGCCTAATAGAAGC
GTATAGATCCTGGTTACCGGTAAGCGAAACCACACCTGTAGTGACCCTCAAAGAAGGAGCGACGCCATTGATCCCTGTCA
GCTCCATAGCTGAACAGATTGGCAGGGGAGTCAAGGTCTACGTGAAATACGACGGCCTCAACCCCACAGGGTCCTTTAAG
GACAGAGGCATGACTATGGCGATCAGCAAGGCCAAAGAAGCTAATTGTGAAGGAGTCATATGTGCCAGTACAGGCAACAC
ATCTGCTGCTGCTGCTGCATATGCAAAACGCGCTGGTATGCGTGCTTTTGTATTAATTCCAGACGGTTATGTAGCGCAAG
GAAAATTAGCTCAAGCTTTAGTTTATGGCGCTGAAGTGCTAGCAATTCGAGGCAATTTTGATCGTGCTCTCGACATTGTT
CAAGAAATGGCCTTGAAATACCCAGTAACTCTGGTGAATTCCGTTAACCCCTACCGGCTTCAAGGTCAAAAAACTGCAGC
CTTTGAAATTGTTGATGCTCTCGGAGAAGCGCCAGAATGGCTGTGCATCCCAATGGGTAATGCAGGTAACATCACTGCTT
ATTGGATGGGTTTTCAAGAATACAAACAAGCCGGAAAATGTCAACTTCTACCACAAATGATGGGATTCCAAGCAAGTGGG
TCTGCTCCATTAGTTTTCAACAAGACCGTAAACAATCCAAATACAATTGCAACAGCAATTAGAATAGGCAACCCAGTCAA
CAAAGAAAAGGCCATTGCCGCAAAGTCAAGCAGTAATGGAGCCTTTCTTGATGTTTCAGATGAAAAAATTCTAGAAGCTT
ACAAATTGCTTGGTCGCGAGGAAGGCATTTTCTGTGAACCTGCAAGTGCTGCTTCTGTAGCAGGATTATTAAAACGTGCG
TCTGAAGTCCCTTCAGGGGCAACAGTTGTATGTGTCCTTACTGGCAACGGTTTAAAAGATCCAGATTGTGCCATCAATAA
CAACGATGCAATATTTCATGCAGATCTAAATCCAGATCTAACCACTGTGGCTCATGTCATGGGTTTTTAA

Upstream 100 bases:

>100_bases
TGGTCTAGTGAAATTCTTTTCCGATTCGCCACTAGACGGCCTTAAGGGATCTAAGCCTTAAGGCTTAGATTCCAACTAAA
AACTGCTCTCTTGCTCTCTA

Downstream 100 bases:

>100_bases
GGAGCAAGCAAACACCAGCATCTCGAATAGACCATCTAAAATCTGACTGTGGAAATCATGCTCGAATTATTATTAAAACT
GGGGAAAAGGCCGCAAAACC

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MVSLSQNLPQAISTTPVMQDWPGLIEAYRSWLPVSETTPVVTLKEGATPLIPVSSIAEQIGRGVKVYVKYDGLNPTGSFK
DRGMTMAISKAKEANCEGVICASTGNTSAAAAAYAKRAGMRAFVLIPDGYVAQGKLAQALVYGAEVLAIRGNFDRALDIV
QEMALKYPVTLVNSVNPYRLQGQKTAAFEIVDALGEAPEWLCIPMGNAGNITAYWMGFQEYKQAGKCQLLPQMMGFQASG
SAPLVFNKTVNNPNTIATAIRIGNPVNKEKAIAAKSSSNGAFLDVSDEKILEAYKLLGREEGIFCEPASAASVAGLLKRA
SEVPSGATVVCVLTGNGLKDPDCAINNNDAIFHADLNPDLTTVAHVMGF

Sequences:

>Translated_369_residues
MVSLSQNLPQAISTTPVMQDWPGLIEAYRSWLPVSETTPVVTLKEGATPLIPVSSIAEQIGRGVKVYVKYDGLNPTGSFK
DRGMTMAISKAKEANCEGVICASTGNTSAAAAAYAKRAGMRAFVLIPDGYVAQGKLAQALVYGAEVLAIRGNFDRALDIV
QEMALKYPVTLVNSVNPYRLQGQKTAAFEIVDALGEAPEWLCIPMGNAGNITAYWMGFQEYKQAGKCQLLPQMMGFQASG
SAPLVFNKTVNNPNTIATAIRIGNPVNKEKAIAAKSSSNGAFLDVSDEKILEAYKLLGREEGIFCEPASAASVAGLLKRA
SEVPSGATVVCVLTGNGLKDPDCAINNNDAIFHADLNPDLTTVAHVMGF
>Mature_369_residues
MVSLSQNLPQAISTTPVMQDWPGLIEAYRSWLPVSETTPVVTLKEGATPLIPVSSIAEQIGRGVKVYVKYDGLNPTGSFK
DRGMTMAISKAKEANCEGVICASTGNTSAAAAAYAKRAGMRAFVLIPDGYVAQGKLAQALVYGAEVLAIRGNFDRALDIV
QEMALKYPVTLVNSVNPYRLQGQKTAAFEIVDALGEAPEWLCIPMGNAGNITAYWMGFQEYKQAGKCQLLPQMMGFQASG
SAPLVFNKTVNNPNTIATAIRIGNPVNKEKAIAAKSSSNGAFLDVSDEKILEAYKLLGREEGIFCEPASAASVAGLLKRA
SEVPSGATVVCVLTGNGLKDPDCAINNNDAIFHADLNPDLTTVAHVMGF

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 39126; Mature: 39126

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLSQNLPQAISTTPVMQDWPGLIEAYRSWLPVSETTPVVTLKEGATPLIPVSSIAEQI
CCCCCCCCCHHHCCCCCHHCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEHHHHHHHH
GRGVKVYVKYDGLNPTGSFKDRGMTMAISKAKEANCEGVICASTGNTSAAAAAYAKRAGM
CCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCC
RAFVLIPDGYVAQGKLAQALVYGAEVLAIRGNFDRALDIVQEMALKYPVTLVNSVNPYRL
EEEEEECCCCCCCCHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHCCCCEECCCCCEEE
QGQKTAAFEIVDALGEAPEWLCIPMGNAGNITAYWMGFQEYKQAGKCQLLPQMMGFQASG
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECHHHHHCCCCEEECHHHHCCCCCC
SAPLVFNKTVNNPNTIATAIRIGNPVNKEKAIAAKSSSNGAFLDVSDEKILEAYKLLGRE
CCCEEEECCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHCCC
EGIFCEPASAASVAGLLKRASEVPSGATVVCVLTGNGLKDPDCAINNNDAIFHADLNPDL
CCCEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCCCEEEEECCCCCH
TTVAHVMGF
HHHHHHHCC
>Mature Secondary Structure
MVSLSQNLPQAISTTPVMQDWPGLIEAYRSWLPVSETTPVVTLKEGATPLIPVSSIAEQI
CCCCCCCCCHHHCCCCCHHCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEHHHHHHHH
GRGVKVYVKYDGLNPTGSFKDRGMTMAISKAKEANCEGVICASTGNTSAAAAAYAKRAGM
CCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHCCC
RAFVLIPDGYVAQGKLAQALVYGAEVLAIRGNFDRALDIVQEMALKYPVTLVNSVNPYRL
EEEEEECCCCCCCCHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHCCCCEECCCCCEEE
QGQKTAAFEIVDALGEAPEWLCIPMGNAGNITAYWMGFQEYKQAGKCQLLPQMMGFQASG
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECHHHHHCCCCEEECHHHHCCCCCC
SAPLVFNKTVNNPNTIATAIRIGNPVNKEKAIAAKSSSNGAFLDVSDEKILEAYKLLGRE
CCCEEEECCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHCCC
EGIFCEPASAASVAGLLKRASEVPSGATVVCVLTGNGLKDPDCAINNNDAIFHADLNPDL
CCCEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCCCEEEEECCCCCH
TTVAHVMGF
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]