Click here to switch to the map view.

The map label for this gene is murG [H]

Identifier: 33864365

GI number: 33864365

Start: 2214774

End: 2215859

Strand: Reverse

Name: murG [H]

Synonym: PMT2101

Alternate gene names: 33864365

Gene position: 2215859-2214774 (Counterclockwise)

Preceding gene: 33864367

Following gene: 33864363

Centisome position: 91.91

GC content: 60.77

Gene sequence:

>1086_bases
ATGCCCAGGCTTCTGATTGCTGCAAGCGGCACCGGTGGCCATCTTTTTCCAGCACTGGCTGTTGCCGAAGCCTTGCCCGG
CTCCTGGAGCGTGTGCTGGCTGGGAGTGCCAGATCGCCTAGAAACCCAACTGGTGCCAGAACGCTATGAGCTGACCACTG
TGCGCGCCGGCGGTCTACAAGGTCGCGGCCTGCGCAAGTTGGTGCAGTTGTTGCAATTACTCGCTGCCACTGGCCGGGTC
AGAAAGCTACTGCGCAAGCAAGGCATCCAGACTGTTTTCACGACTGGGGGCTATATCGCCGCACCAGCAATCTTGGCGGC
TCGCTGGTGCGGAATCCCTGTGGTGCTGCACGAATCCAATGCCATCCCCGGACGAGTGACGCGCTTATTGGGCCGCTTCT
GCCAGGTCGTGGCTGTAGGCCTCTCTGTTGCTGCTAAGCGCATCCCAGGCAGCAAAGCTGTGGTCACAGGAACACCGGTG
CGCTCGGCATTCCTTTCGCCACAGCCCTTGCCGCGTTGGGTTCCTTGCGGTGATGGCCCATTGCTGGTGGTGATTGGTGG
TAGTCAAGGGGCCGTCGGACTCAACCGCATGGTGCGAGGCGCACTGCCATCGCTGCTGGAGGCCGGTTGTCGCGTGGTGC
ATCTCACCGGCAACAACGATTCAGATGTAGGAGAACTCGATCACCCCAACCTGGTGGAACAGCCTTTCAGCCATGAGATG
CCTGGTTTGCTGCAACATGCCGATCTCGCCATCAGCCGTGCGGGCGCCGGCAGCCTGAGTGAATTGGCCGTCTGTGGCAC
CCCAGCCATCTTGGTGCCCTTCCCCCAAGCGGCAGACCAGCATCAAGAGGCCAACGCAGCCTGCGCCGCTGCGCTTGGGG
CTGCCGTGATCGTGCATCAACATGCAGCCGAACATCGGGCTCTTGGTCATGCTCTGGAACAACTCATGGGACCTCGCCTA
CGCGGCAACGCTGCTGCCAGCAACCCTTTAATTCCCATGAAGCAAGGCATGAGGAAGTTGGCAGTGCGTGAGGCAGACCA
GCTGCTGGTGACATTGCTGAAGCAACTCATCGGAGCAGGGCTTTGA

Upstream 100 bases:

>100_bases
AGCAGACTGGAGGCCAAAGCGATTGGCTTGAGATGAGGCACTGGAGGCTTGAGGGCACTGCCGATAAGTTAGGCCGCACC
TTCATGCTCTGCCCATTGCC

Downstream 100 bases:

>100_bases
ACGCAGCAAGGATGCGGCGATTGGCTGACCTCTGCTGCAAACCAATGCGCAACCAGCGCTCCCCAAGTTCTGCAAAGGAG
CGGCAGTCACGCAACAGCAC

Product: undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MPRLLIAASGTGGHLFPALAVAEALPGSWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRV
RKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPV
RSAFLSPQPLPRWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDSDVGELDHPNLVEQPFSHEM
PGLLQHADLAISRAGAGSLSELAVCGTPAILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGPRL
RGNAAASNPLIPMKQGMRKLAVREADQLLVTLLKQLIGAGL

Sequences:

>Translated_361_residues
MPRLLIAASGTGGHLFPALAVAEALPGSWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRV
RKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPV
RSAFLSPQPLPRWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDSDVGELDHPNLVEQPFSHEM
PGLLQHADLAISRAGAGSLSELAVCGTPAILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGPRL
RGNAAASNPLIPMKQGMRKLAVREADQLLVTLLKQLIGAGL
>Mature_360_residues
PRLLIAASGTGGHLFPALAVAEALPGSWSVCWLGVPDRLETQLVPERYELTTVRAGGLQGRGLRKLVQLLQLLAATGRVR
KLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESNAIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVR
SAFLSPQPLPRWVPCGDGPLLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDSDVGELDHPNLVEQPFSHEMP
GLLQHADLAISRAGAGSLSELAVCGTPAILVPFPQAADQHQEANAACAAALGAAVIVHQHAAEHRALGHALEQLMGPRLR
GNAAASNPLIPMKQGMRKLAVREADQLLVTLLKQLIGAGL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=310, Percent_Identity=36.4516129032258, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 37738; Mature: 37607

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLLIAASGTGGHLFPALAVAEALPGSWSVCWLGVPDRLETQLVPERYELTTVRAGGLQ
CCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEEEEECCCCC
GRGLRKLVQLLQLLAATGRVRKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCC
AIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVRSAFLSPQPLPRWVPCGDGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCC
LLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDSDVGELDHPNLVEQPFSHEM
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCCC
PGLLQHADLAISRAGAGSLSELAVCGTPAILVPFPQAADQHQEANAACAAALGAAVIVHQ
CHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HAAEHRALGHALEQLMGPRLRGNAAASNPLIPMKQGMRKLAVREADQLLVTLLKQLIGAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
L
C
>Mature Secondary Structure 
PRLLIAASGTGGHLFPALAVAEALPGSWSVCWLGVPDRLETQLVPERYELTTVRAGGLQ
CCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEEEEECCCCC
GRGLRKLVQLLQLLAATGRVRKLLRKQGIQTVFTTGGYIAAPAILAARWCGIPVVLHESN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCC
AIPGRVTRLLGRFCQVVAVGLSVAAKRIPGSKAVVTGTPVRSAFLSPQPLPRWVPCGDGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCC
LLVVIGGSQGAVGLNRMVRGALPSLLEAGCRVVHLTGNNDSDVGELDHPNLVEQPFSHEM
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCCC
PGLLQHADLAISRAGAGSLSELAVCGTPAILVPFPQAADQHQEANAACAAALGAAVIVHQ
CHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HAAEHRALGHALEQLMGPRLRGNAAASNPLIPMKQGMRKLAVREADQLLVTLLKQLIGAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA