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The map label for this gene is lytB [H]

Identifier: 33864121

GI number: 33864121

Start: 1961933

End: 1963129

Strand: Direct

Name: lytB [H]

Synonym: PMT1854

Alternate gene names: 33864121

Gene position: 1961933-1963129 (Clockwise)

Preceding gene: 33864120

Following gene: 33864122

Centisome position: 81.38

GC content: 49.87

Gene sequence:

>1197_bases
ATGGATACACAAGCTTTCAAACGCTCACTCCATCACTCTGAGCGTTACAACCGTAGGGGCTTCGGGCGAGCCAACGAAGT
CGCCAGCAACCTTGAGAAGGCCTACCAAAGCAGCCTAATTGGCTCGATTCGAGACAATGGGTATGTGCTTCAACATGGCC
GGCTTCAGGTGAAATTGGCTGAGGCCTTTGGTTTCTGCTGGGGAGTAGAGAGAGCAGTTGCGATGGCCTATGAAACCCGT
AGGCACTACCCAAGCGAGCGCATTTGGATTACTAACGAAATTATTCACAACCCTTCAGTGAATGAACACTTACGCGAAAT
GGACGTGCTGTTCATCCACGCTGAAGGAGGTGTCAAAGATTTTTCCTGCGTCAATGATGGCGATGTAGTGATCCTGCCCG
CCTTCGGTGCCACTGTTCAGGAGATGGAGCTGCTTCATGAGCGTGGCTGTCACATCATCGACACCACTTGTCCATGGGTT
TCCAAGGTGTGGCACACCGTGGAGAAACATAAGAAGCAAGAATTCACCTCAATTATTCATGGCAAGGTGAAGCATGAAGA
AACCTTGGCCACCAGCTCCTTTGCAGGGACCTATCTAGTTGTTTTAGACCTTGATGAAGCCCAACTAGTCGCCGATTACA
TCCTGGGCCAAGGAGATCGTGCAGCGTTCATGAAACGCTTTGCTAAGGCATGCTCTGCAAACTTTGACCCAGATCAAGAT
CTCCAACGCCTTGGGGTAGCCAATCAGACCACCATGCTGAAAAGTGAAACCGAGGAAATCGGTCGTTTATTCGAGCGCAC
CATGCTCAGAAAATATGGCCCAATAGAGCTCAACAAACATTTCCTTTCCTTCAACACCATCTGTGACGCCACAGAGGAAC
GGCAACAAGCAATGTTCTCGCTAGTTGATGAGCCTCTAGATCTACTGGTGGTGATTGGTGGTTTCAACTCATCCAACACC
ACTCACCTACAGGAAATCGCCATCAGCCGAGGAATCCGATCCTTCCACATCGATACCCCAGAACGTATTGGTGATAACAA
CAGCATCCAACACAAGCCACTGGGAGAAGATCTGTTCATCGAAAGTAATTTTCTACCTGCTGGAAGCGTGAGCGTCGGCA
TCACCTCCGGAGCCTCAACACCCGATCGAGTAGTTGAACATGTGATTCAGAAGCTGATCGACCTAACCTCCGGCTGA

Upstream 100 bases:

>100_bases
TCAACAACCTGAATCCCATTAAGCCCGACCCTGTGCCGGGCTTTTTTGTGCTTCAAAAGTGTTGAGCTGCCCATAGAGTC
AGGAGATTGCTGCTGCCACG

Downstream 100 bases:

>100_bases
ACAACACCCTGGCTTTACATTTGTTAATATCCCAGGCCAACCCAGCCAGGGATGACCATCCGTGCCGCCCTTGTCGATAC
CTGCCGACCAATATCTGCGC

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDTQAFKRSLHHSERYNRRGFGRANEVASNLEKAYQSSLIGSIRDNGYVLQHGRLQVKLAEAFGFCWGVERAVAMAYETR
RHYPSERIWITNEIIHNPSVNEHLREMDVLFIHAEGGVKDFSCVNDGDVVILPAFGATVQEMELLHERGCHIIDTTCPWV
SKVWHTVEKHKKQEFTSIIHGKVKHEETLATSSFAGTYLVVLDLDEAQLVADYILGQGDRAAFMKRFAKACSANFDPDQD
LQRLGVANQTTMLKSETEEIGRLFERTMLRKYGPIELNKHFLSFNTICDATEERQQAMFSLVDEPLDLLVVIGGFNSSNT
THLQEIAISRGIRSFHIDTPERIGDNNSIQHKPLGEDLFIESNFLPAGSVSVGITSGASTPDRVVEHVIQKLIDLTSG

Sequences:

>Translated_398_residues
MDTQAFKRSLHHSERYNRRGFGRANEVASNLEKAYQSSLIGSIRDNGYVLQHGRLQVKLAEAFGFCWGVERAVAMAYETR
RHYPSERIWITNEIIHNPSVNEHLREMDVLFIHAEGGVKDFSCVNDGDVVILPAFGATVQEMELLHERGCHIIDTTCPWV
SKVWHTVEKHKKQEFTSIIHGKVKHEETLATSSFAGTYLVVLDLDEAQLVADYILGQGDRAAFMKRFAKACSANFDPDQD
LQRLGVANQTTMLKSETEEIGRLFERTMLRKYGPIELNKHFLSFNTICDATEERQQAMFSLVDEPLDLLVVIGGFNSSNT
THLQEIAISRGIRSFHIDTPERIGDNNSIQHKPLGEDLFIESNFLPAGSVSVGITSGASTPDRVVEHVIQKLIDLTSG
>Mature_398_residues
MDTQAFKRSLHHSERYNRRGFGRANEVASNLEKAYQSSLIGSIRDNGYVLQHGRLQVKLAEAFGFCWGVERAVAMAYETR
RHYPSERIWITNEIIHNPSVNEHLREMDVLFIHAEGGVKDFSCVNDGDVVILPAFGATVQEMELLHERGCHIIDTTCPWV
SKVWHTVEKHKKQEFTSIIHGKVKHEETLATSSFAGTYLVVLDLDEAQLVADYILGQGDRAAFMKRFAKACSANFDPDQD
LQRLGVANQTTMLKSETEEIGRLFERTMLRKYGPIELNKHFLSFNTICDATEERQQAMFSLVDEPLDLLVVIGGFNSSNT
THLQEIAISRGIRSFHIDTPERIGDNNSIQHKPLGEDLFIESNFLPAGSVSVGITSGASTPDRVVEHVIQKLIDLTSG

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=349, Percent_Identity=27.2206303724928, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 44757; Mature: 44757

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQAFKRSLHHSERYNRRGFGRANEVASNLEKAYQSSLIGSIRDNGYVLQHGRLQVKLA
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEHH
EAFGFCWGVERAVAMAYETRRHYPSERIWITNEIIHNPSVNEHLREMDVLFIHAEGGVKD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHCEEEEEECCCCCCC
FSCVNDGDVVILPAFGATVQEMELLHERGCHIIDTTCPWVSKVWHTVEKHKKQEFTSIIH
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GKVKHEETLATSSFAGTYLVVLDLDEAQLVADYILGQGDRAAFMKRFAKACSANFDPDQD
CHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHH
LQRLGVANQTTMLKSETEEIGRLFERTMLRKYGPIELNKHFLSFNTICDATEERQQAMFS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHEEHHHHHCHHHHHHHHHHH
LVDEPLDLLVVIGGFNSSNTTHLQEIAISRGIRSFHIDTPERIGDNNSIQHKPLGEDLFI
HHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCHHHCCCCCCCCCCCCCCCEEE
ESNFLPAGSVSVGITSGASTPDRVVEHVIQKLIDLTSG
ECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTQAFKRSLHHSERYNRRGFGRANEVASNLEKAYQSSLIGSIRDNGYVLQHGRLQVKLA
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEHH
EAFGFCWGVERAVAMAYETRRHYPSERIWITNEIIHNPSVNEHLREMDVLFIHAEGGVKD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHCEEEEEECCCCCCC
FSCVNDGDVVILPAFGATVQEMELLHERGCHIIDTTCPWVSKVWHTVEKHKKQEFTSIIH
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GKVKHEETLATSSFAGTYLVVLDLDEAQLVADYILGQGDRAAFMKRFAKACSANFDPDQD
CHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHH
LQRLGVANQTTMLKSETEEIGRLFERTMLRKYGPIELNKHFLSFNTICDATEERQQAMFS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHEEHHHHHCHHHHHHHHHHH
LVDEPLDLLVVIGGFNSSNTTHLQEIAISRGIRSFHIDTPERIGDNNSIQHKPLGEDLFI
HHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCHHHCCCCCCCCCCCCCCCEEE
ESNFLPAGSVSVGITSGASTPDRVVEHVIQKLIDLTSG
ECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA