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The map label for this gene is kdgA [H]

Identifier: 33864064

GI number: 33864064

Start: 1898445

End: 1899131

Strand: Reverse

Name: kdgA [H]

Synonym: PMT1797

Alternate gene names: 33864064

Gene position: 1899131-1898445 (Counterclockwise)

Preceding gene: 33864065

Following gene: 33864063

Centisome position: 78.77

GC content: 54.15

Gene sequence:

>687_bases
TTGCCGAATACGTCTGAGCGCTCTGGTGATTGCCTCTGGCTTGATAGGCAAGAGATCTTGATAGCCTCACTACGGGCCCA
GCCTTTGGTTGTGGTATTGCGTAGCGAGCACGACGATCTTGAGGGATCTAGCTCTAGAGCTTCTTTGTTTGCGGTTTTCG
AGCAGTTGCATCTTCTCGGAGTTCGGCATGTGGAGCTGGCCTGGTCTCCTCATCCTGGTTGGATGTCTTTGATGAAGGAG
GTGCAGAAGTGCTTTGCAGGGCTCTGCCTGGGAGCAGCCTCTATTAGCTGTCCAGAAGCCTTGCAGTCTGTGGCAGAGCT
AGGCCTTGCTTATGCCATGACTTCATATTGGGATCCCGACCTTCATCAGAAGGCGCGGGAAATGCATCAGCTCCTTGTGC
CTGGGGTGTTCACTCCCACTGAGATTCAGCAGGCTTACCGTTGTGGATGCCGGCTCGTTAAGTTGTTCCCTGCATCAGTT
TTGGGGGTTGATTACTGGCGTCAGTTGGCTGGACCGATGGAGGCTTTGCCCTTTGTGATTGCCGCTGGTGGGCTTACGGT
TCAAGACTTCATCCCCTGGCTTAATGCGGGGTATGACGCTGTTGCCCTTGGGCGTGGGCTGGTTCAACAGGGGCAACTTG
ACCCTGCATTGCAGGCTTATTTGAAGCCTCCAGCAACGACAGCTTAA

Upstream 100 bases:

>100_bases
AATCGTTCTGTTCTTGATGAGTTGGCTGATTTGCTTGTAGAGAAGGAAACACTTGATGCTCAGGATTTGCAGGAATTGTT
GATCCGACGCGATGTAAGGG

Downstream 100 bases:

>100_bases
CTTCGACTATTTGTTGACATTCGATCGAGATGCTACATATAAGATAGCTATTTATTCTTCAATGTCTCAGCTAACCATCA
AGCTAAGCGTTAAAGCCGAT

Product: aldolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPNTSERSGDCLWLDRQEILIASLRAQPLVVVLRSEHDDLEGSSSRASLFAVFEQLHLLGVRHVELAWSPHPGWMSLMKE
VQKCFAGLCLGAASISCPEALQSVAELGLAYAMTSYWDPDLHQKAREMHQLLVPGVFTPTEIQQAYRCGCRLVKLFPASV
LGVDYWRQLAGPMEALPFVIAAGGLTVQDFIPWLNAGYDAVALGRGLVQQGQLDPALQAYLKPPATTA

Sequences:

>Translated_228_residues
MPNTSERSGDCLWLDRQEILIASLRAQPLVVVLRSEHDDLEGSSSRASLFAVFEQLHLLGVRHVELAWSPHPGWMSLMKE
VQKCFAGLCLGAASISCPEALQSVAELGLAYAMTSYWDPDLHQKAREMHQLLVPGVFTPTEIQQAYRCGCRLVKLFPASV
LGVDYWRQLAGPMEALPFVIAAGGLTVQDFIPWLNAGYDAVALGRGLVQQGQLDPALQAYLKPPATTA
>Mature_227_residues
PNTSERSGDCLWLDRQEILIASLRAQPLVVVLRSEHDDLEGSSSRASLFAVFEQLHLLGVRHVELAWSPHPGWMSLMKEV
QKCFAGLCLGAASISCPEALQSVAELGLAYAMTSYWDPDLHQKAREMHQLLVPGVFTPTEIQQAYRCGCRLVKLFPASVL
GVDYWRQLAGPMEALPFVIAAGGLTVQDFIPWLNAGYDAVALGRGLVQQGQLDPALQAYLKPPATTA

Specific function: Unknown

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI48994954, Length=186, Percent_Identity=26.3440860215054, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 24970; Mature: 24839

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00160 ALDOLASE_KDPG_KHG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTSERSGDCLWLDRQEILIASLRAQPLVVVLRSEHDDLEGSSSRASLFAVFEQLHLLG
CCCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHC
VRHVELAWSPHPGWMSLMKEVQKCFAGLCLGAASISCPEALQSVAELGLAYAMTSYWDPD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCH
LHQKAREMHQLLVPGVFTPTEIQQAYRCGCRLVKLFPASVLGVDYWRQLAGPMEALPFVI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AAGGLTVQDFIPWLNAGYDAVALGRGLVQQGQLDPALQAYLKPPATTA
HCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
PNTSERSGDCLWLDRQEILIASLRAQPLVVVLRSEHDDLEGSSSRASLFAVFEQLHLLG
CCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHC
VRHVELAWSPHPGWMSLMKEVQKCFAGLCLGAASISCPEALQSVAELGLAYAMTSYWDPD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCH
LHQKAREMHQLLVPGVFTPTEIQQAYRCGCRLVKLFPASVLGVDYWRQLAGPMEALPFVI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AAGGLTVQDFIPWLNAGYDAVALGRGLVQQGQLDPALQAYLKPPATTA
HCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]