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The map label for this gene is minD [H]

Identifier: 33863920

GI number: 33863920

Start: 1760601

End: 1761416

Strand: Direct

Name: minD [H]

Synonym: PMT1653

Alternate gene names: 33863920

Gene position: 1760601-1761416 (Clockwise)

Preceding gene: 33863919

Following gene: 33863921

Centisome position: 73.03

GC content: 56.5

Gene sequence:

>816_bases
GTGGCGCCAACGACACGCACCATTCTGATCTGCTCCGGAAAAGGAGGTGTCGGCAAAACCACCCTCACCGCCAACCTGGG
TATCGCTCTTGCCAAGCTTGGAGTTCAAACCGTTGTGTTGGATGCCGATTTCGGCTTGCGCAACCTCGATCTACTACTGG
GCCTGGAGAACCGAATCGTCTACACCGCCCAGGAAGTGCTCTCAGAGAACTGCAGGCTTGATCAGGCCCTGGTGAAACAC
AAGCAGGAGCCAAACCTCTCCCTTCTGCCCGCCGGGAACCCCCGCATGCTCGAGTGGCTCAAACCTGAGGACATGCAACG
CATTGCCGCGATGCTGGCCAAGCAATTCGACTATGTATTGATTGATTGCCCCGCGGGGATCGAAGACGGCTTCAAAAATG
CTGTTGCTGCCGCCAAGGAAGCAATCGTGATCACAACGCCTGAGGTTTCAGCAGTGCGCGATGCCGACCGTGTCATCGGC
TTACTGAACACCCATGGCGTAAGCCCTGTTCAGCTGGTGCTCAACAGGGTGCGTCCAAAGATGATGGCCAATCAAGAGAT
GCTGGCCGCAGACGATGTGACCGACATCCTGGCGCTGCCCTTGCTTGGTTTAGTTCTAGAGGACGAACAGGTGATTGTGA
GCACCAACCGCGGAGAGCCGCTCACCCTCAGTGCCAACAACTCTCCAGCCTCTCGTGCCTACTCCAACATTGCGCGTCGC
CTTCAAGGGGAAGATGTTCCTCTGATCGATCCGGCCAAGGAAGGACTGGGACTACGCGAAAAGGTGTGGCGCTTGATGCA
AACCAAGATCTTTTGA

Upstream 100 bases:

>100_bases
CCCGTTGAACAAAGCCCATTTGTTCCATTGCAAACCTTGGACCATTTCTCTTGGGCCTATTGCCTACGCCACTTAAGCTG
ACCGCACTTTTCAATGGCCC

Downstream 100 bases:

>100_bases
AGTAATGGCAACCACTCTGCGAGACATTCTTGACAAATTGCTGGGCCGCCAACCAGCCAGTGCCAAAACGGCAAGGGAGC
GCCTTCAGCTTGTGCTTGCC

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAPTTRTILICSGKGGVGKTTLTANLGIALAKLGVQTVVLDADFGLRNLDLLLGLENRIVYTAQEVLSENCRLDQALVKH
KQEPNLSLLPAGNPRMLEWLKPEDMQRIAAMLAKQFDYVLIDCPAGIEDGFKNAVAAAKEAIVITTPEVSAVRDADRVIG
LLNTHGVSPVQLVLNRVRPKMMANQEMLAADDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLSANNSPASRAYSNIARR
LQGEDVPLIDPAKEGLGLREKVWRLMQTKIF

Sequences:

>Translated_271_residues
MAPTTRTILICSGKGGVGKTTLTANLGIALAKLGVQTVVLDADFGLRNLDLLLGLENRIVYTAQEVLSENCRLDQALVKH
KQEPNLSLLPAGNPRMLEWLKPEDMQRIAAMLAKQFDYVLIDCPAGIEDGFKNAVAAAKEAIVITTPEVSAVRDADRVIG
LLNTHGVSPVQLVLNRVRPKMMANQEMLAADDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLSANNSPASRAYSNIARR
LQGEDVPLIDPAKEGLGLREKVWRLMQTKIF
>Mature_270_residues
APTTRTILICSGKGGVGKTTLTANLGIALAKLGVQTVVLDADFGLRNLDLLLGLENRIVYTAQEVLSENCRLDQALVKHK
QEPNLSLLPAGNPRMLEWLKPEDMQRIAAMLAKQFDYVLIDCPAGIEDGFKNAVAAAKEAIVITTPEVSAVRDADRVIGL
LNTHGVSPVQLVLNRVRPKMMANQEMLAADDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLSANNSPASRAYSNIARRL
QGEDVPLIDPAKEGLGLREKVWRLMQTKIF

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI118572611, Length=265, Percent_Identity=26.7924528301887, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI6912540, Length=263, Percent_Identity=25.0950570342205, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787423, Length=262, Percent_Identity=41.6030534351145, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6322188, Length=173, Percent_Identity=28.3236994219653, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24667611, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29450; Mature: 29319

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTTRTILICSGKGGVGKTTLTANLGIALAKLGVQTVVLDADFGLRNLDLLLGLENRIV
CCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHCEEEEEEECCCCCCCCCEEEECCCCEE
YTAQEVLSENCRLDQALVKHKQEPNLSLLPAGNPRMLEWLKPEDMQRIAAMLAKQFDYVL
EHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCHHEECCCCHHHHHHHHHHHHCCCEEE
IDCPAGIEDGFKNAVAAAKEAIVITTPEVSAVRDADRVIGLLNTHGVSPVQLVLNRVRPK
EECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHH
MMANQEMLAADDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLSANNSPASRAYSNIARR
HHCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LQGEDVPLIDPAKEGLGLREKVWRLMQTKIF
HCCCCCCCCCCHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
APTTRTILICSGKGGVGKTTLTANLGIALAKLGVQTVVLDADFGLRNLDLLLGLENRIV
CCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHCEEEEEEECCCCCCCCCEEEECCCCEE
YTAQEVLSENCRLDQALVKHKQEPNLSLLPAGNPRMLEWLKPEDMQRIAAMLAKQFDYVL
EHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCHHEECCCCHHHHHHHHHHHHCCCEEE
IDCPAGIEDGFKNAVAAAKEAIVITTPEVSAVRDADRVIGLLNTHGVSPVQLVLNRVRPK
EECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHH
MMANQEMLAADDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLSANNSPASRAYSNIARR
HHCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LQGEDVPLIDPAKEGLGLREKVWRLMQTKIF
HCCCCCCCCCCHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]