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The map label for this gene is xseA [H]

Identifier: 33863908

GI number: 33863908

Start: 1743229

End: 1744386

Strand: Direct

Name: xseA [H]

Synonym: PMT1641

Alternate gene names: 33863908

Gene position: 1743229-1744386 (Clockwise)

Preceding gene: 33863907

Following gene: 33863909

Centisome position: 72.31

GC content: 51.81

Gene sequence:

>1158_bases
TTGACCGCTGAATCCCTTCCAAACTATTCAGTCCGCGATCTCAACGCGGCTATTGGCACTCTGCTGGAACGTGGCTTTGC
ACCTCGATTTCTGGTGGAAGCGTCAGTCTCCAAGCCACAGATCAAAAAAGGTCATCTCTGGCTAACTCTGACTGACGGCA
ACGCAAGTATCACGGCAGTGGCTTGGGCTTCCAAGCTGCAGCAACTCACCTACAGGCCTGCAGAAGGGGATGGGGTAACG
GTTGTCGGCAAGCTCAACTTCTGGGCAACCCGAGCAAGCCTGGCCGTGCAAGTCATAGACCTGCGTCCGTCCCTATCGAC
GGTGCTACGTCAGTTCGAAATTGTGAAAGCCCTGCTATTGAAAGAGGGCCTCATCGACGAATCGAAACAGAAAGCGTTAC
CAAAATATCCAGAGGTTGTAGCCATCTTGACCAGCGTGCCGAGTTCCGCCCTGGCAGACATGCTGCGTACAGCAAAAGAG
CGCTGGCCTCTAACTCAATTGCTGATCATTCCAATTCCAGTCCAAGGTGGTGTAGCAAAACAAATCCAATCCGTTTTACG
TTCTCTGGCTAATCAACATGATGAGCTGGGGATTGCAGCGATCGTGCTGGCCAGAGGAGGTGGCAGTCGTGAAGACCTGA
TGGTGTTTGATGATGAAGACCTATGCCGTGACCTGGCCAGTTTCCCAATACCGGTGGTGACTGGACTAGGGCATGAGGAT
GACCAAACAGTGGCTGATCTGGTTGCTGACCATAGAGCCGCGACTCCAACCGCAGCGATGGTGGCCCTGTTGCCCAGTCG
GGAGTCAGCTCAAAATGTGCTGATGCAACGCCGTCATCGACTTAAAGACCATTGCAATTGGCTCATTCGCAAAGAACGTG
AGCGGCTTGTAATGCGAGGTAAAGCGTTGGAGTGTCAACAACCGCTGAAACAGATAGAGCTTCAGCGCATTCACTTAAGC
CAGAAGCATCAGCTCCTCCAAGCTCTATCACCAGAACTCTGGTTGATGCGCGGTTTTGCCATCGTGAAGAACAAGCAAGG
TAAAACTCTTCGAAGCGTTGGTAATGTATCTGTGCTGGACAATTTGACCATCCAGCTCAGTGATGGCCAGATCAATACCA
CCGCAGAAGCAATTAATCAACAAAGGCTCTCGACATGA

Upstream 100 bases:

>100_bases
TTCACAATCGCATCCACCCAACTGGATCATGCCTGGGGGCAAGCTGTTGCTGCTCTTAGCGTCGTGATCTGCCTCTACTG
GGGCATGGCCTACCGACGCC

Downstream 100 bases:

>100_bases
TAAAAGCCACTTCATCATCTGAGAAGACACCAAGAGATTCCGGCTCTAAACAGCAAAAGCACGCCATGAATACTGCGCAA
TCAACGCTAGATAGCATGCT

Product: exonuclease VII, large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAVAWASKLQQLTYRPAEGDGVT
VVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLLKEGLIDESKQKALPKYPEVVAILTSVPSSALADMLRTAKE
RWPLTQLLIIPIPVQGGVAKQIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLMQRRHRLKDHCNWLIRKERERLVMRGKALECQQPLKQIELQRIHLS
QKHQLLQALSPELWLMRGFAIVKNKQGKTLRSVGNVSVLDNLTIQLSDGQINTTAEAINQQRLST

Sequences:

>Translated_385_residues
MTAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAVAWASKLQQLTYRPAEGDGVT
VVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLLKEGLIDESKQKALPKYPEVVAILTSVPSSALADMLRTAKE
RWPLTQLLIIPIPVQGGVAKQIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLMQRRHRLKDHCNWLIRKERERLVMRGKALECQQPLKQIELQRIHLS
QKHQLLQALSPELWLMRGFAIVKNKQGKTLRSVGNVSVLDNLTIQLSDGQINTTAEAINQQRLST
>Mature_384_residues
TAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAVAWASKLQQLTYRPAEGDGVTV
VGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLLKEGLIDESKQKALPKYPEVVAILTSVPSSALADMLRTAKER
WPLTQLLIIPIPVQGGVAKQIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHEDD
QTVADLVADHRAATPTAAMVALLPSRESAQNVLMQRRHRLKDHCNWLIRKERERLVMRGKALECQQPLKQIELQRIHLSQ
KHQLLQALSPELWLMRGFAIVKNKQGKTLRSVGNVSVLDNLTIQLSDGQINTTAEAINQQRLST

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=310, Percent_Identity=32.258064516129, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 42499; Mature: 42368

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEHH
AWASKLQQLTYRPAEGDGVTVVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLL
HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHH
KEGLIDESKQKALPKYPEVVAILTSVPSSALADMLRTAKERWPLTQLLIIPIPVQGGVAK
HHCCCCCHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHH
QIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCEEECCCCCC
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLMQRRHRLKDHCNWLIRKERERLVMRG
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KALECQQPLKQIELQRIHLSQKHQLLQALSPELWLMRGFAIVKNKQGKTLRSVGNVSVLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHEEECCCCCHHHHCCCEEEEE
NLTIQLSDGQINTTAEAINQQRLST
CEEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TAESLPNYSVRDLNAAIGTLLERGFAPRFLVEASVSKPQIKKGHLWLTLTDGNASITAV
CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEHH
AWASKLQQLTYRPAEGDGVTVVGKLNFWATRASLAVQVIDLRPSLSTVLRQFEIVKALLL
HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHH
KEGLIDESKQKALPKYPEVVAILTSVPSSALADMLRTAKERWPLTQLLIIPIPVQGGVAK
HHCCCCCHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHH
QIQSVLRSLANQHDELGIAAIVLARGGGSREDLMVFDDEDLCRDLASFPIPVVTGLGHED
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCEEECCCCCC
DQTVADLVADHRAATPTAAMVALLPSRESAQNVLMQRRHRLKDHCNWLIRKERERLVMRG
HHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KALECQQPLKQIELQRIHLSQKHQLLQALSPELWLMRGFAIVKNKQGKTLRSVGNVSVLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHEEECCCCCHHHHCCCEEEEE
NLTIQLSDGQINTTAEAINQQRLST
CEEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA