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The map label for this gene is cysH [H]

Identifier: 33863891

GI number: 33863891

Start: 1725130

End: 1725930

Strand: Reverse

Name: cysH [H]

Synonym: PMT1624

Alternate gene names: 33863891

Gene position: 1725930-1725130 (Counterclockwise)

Preceding gene: 33863898

Following gene: 33863890

Centisome position: 71.59

GC content: 54.81

Gene sequence:

>801_bases
ATGACTGATGGCTCCATTGATACGGTTTCCACTGCCACGTCTACTGCGGCAGGCCAATCTCCGAGTGTGCAGGTTGCCTC
GACTCTCGAGATGCCTCTGGAGGATGCACGGATACACCTTGCCAATCTTTCTGCCCAGAAGCGTCTTGAGTGGGCACTGA
AACAGTTTGGTCAAGGCTTTGTTCTGACAACGAGCTTCGGCATTCAATCAGCTGTTCTGCTGCACATGCTCCATGGTCTT
GATGGTGGTTCGGTGGTCCCTGTGGTCTGGGTGGATACGGGCTATCTACCAGCAGAGACCTATTTCTATGCGGATCAGCT
CACGCGTCAGCTTGGGTTGGATTTAAAGGTGGTTCAAAGCACAATGTCTCCCGCTCGGATGGAGGCTATCTATGGCCGGC
TCTGGGAGACAGGTTCGGTGAAGGATCTGGAGACATATCACCGTATTCGCAAGGTGGAGCCCCTCGAGCAGGCTCTGGAT
GATCTCCGTGTGCATTGCTGGGCCAGTGGGGTGCGCAGTGATCAGACCGACTATCGGCGCTCAATGGCTTTTTTGGACCT
GATTCGTGATCGCCTTTCATTGAGGCCTTTACTCGACTGGACTCCCAAGGAGGTTTTCTATTACATGCAGGAGCATCAGT
TGCCGCAGCATCCTCTGTTTGAAAAGGGTTACTCCACGGTCGGCGATTGGCATTCCAGTGCTCCCGATGGGGGGGGGGCT
TCTGGACGGGAGACACGCTTTGGAGGTCTTAAGCAGGAATGCGGCCTTCACCTCCCAGGTGTGTTGGGCGAAGGCATCTA
A

Upstream 100 bases:

>100_bases
CATTGGCGTTTGACGGGTTGGGGATCATGCGCGATGAGCCTGGGATGGTTCTCGAACCTTAAACACTCTGTTGTGAACGG
CGACATTGGAGAATGGGGAG

Downstream 100 bases:

>100_bases
AGGTGGAGGTTGTTAGGCATTGCCTCTTGATTGGCAACAGTCGCTGGCATTGGGCCGAGTATCAGGCTGATGAATGGCAG
TTTTGCCATAGCGTTCCCAA

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTDGSIDTVSTATSTAAGQSPSVQVASTLEMPLEDARIHLANLSAQKRLEWALKQFGQGFVLTTSFGIQSAVLLHMLHGL
DGGSVVPVVWVDTGYLPAETYFYADQLTRQLGLDLKVVQSTMSPARMEAIYGRLWETGSVKDLETYHRIRKVEPLEQALD
DLRVHCWASGVRSDQTDYRRSMAFLDLIRDRLSLRPLLDWTPKEVFYYMQEHQLPQHPLFEKGYSTVGDWHSSAPDGGGA
SGRETRFGGLKQECGLHLPGVLGEGI

Sequences:

>Translated_266_residues
MTDGSIDTVSTATSTAAGQSPSVQVASTLEMPLEDARIHLANLSAQKRLEWALKQFGQGFVLTTSFGIQSAVLLHMLHGL
DGGSVVPVVWVDTGYLPAETYFYADQLTRQLGLDLKVVQSTMSPARMEAIYGRLWETGSVKDLETYHRIRKVEPLEQALD
DLRVHCWASGVRSDQTDYRRSMAFLDLIRDRLSLRPLLDWTPKEVFYYMQEHQLPQHPLFEKGYSTVGDWHSSAPDGGGA
SGRETRFGGLKQECGLHLPGVLGEGI
>Mature_265_residues
TDGSIDTVSTATSTAAGQSPSVQVASTLEMPLEDARIHLANLSAQKRLEWALKQFGQGFVLTTSFGIQSAVLLHMLHGLD
GGSVVPVVWVDTGYLPAETYFYADQLTRQLGLDLKVVQSTMSPARMEAIYGRLWETGSVKDLETYHRIRKVEPLEQALDD
LRVHCWASGVRSDQTDYRRSMAFLDLIRDRLSLRPLLDWTPKEVFYYMQEHQLPQHPLFEKGYSTVGDWHSSAPDGGGAS
GRETRFGGLKQECGLHLPGVLGEGI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=227, Percent_Identity=41.8502202643172, Blast_Score=186, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6325425, Length=225, Percent_Identity=27.1111111111111, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29524; Mature: 29393

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGSIDTVSTATSTAAGQSPSVQVASTLEMPLEDARIHLANLSAQKRLEWALKQFGQGF
CCCCCCCCHHHHHHHCCCCCCCEEHHHHHHCCHHHHEEEHHHCCHHHHHHHHHHHHCCCE
VLTTSFGIQSAVLLHMLHGLDGGSVVPVVWVDTGYLPAETYFYADQLTRQLGLDLKVVQS
EEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHH
TMSPARMEAIYGRLWETGSVKDLETYHRIRKVEPLEQALDDLRVHCWASGVRSDQTDYRR
HCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
SMAFLDLIRDRLSLRPLLDWTPKEVFYYMQEHQLPQHPLFEKGYSTVGDWHSSAPDGGGA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCC
SGRETRFGGLKQECGLHLPGVLGEGI
CCCCCCCCCCHHHCCCCCCCHHCCCC
>Mature Secondary Structure 
TDGSIDTVSTATSTAAGQSPSVQVASTLEMPLEDARIHLANLSAQKRLEWALKQFGQGF
CCCCCCCHHHHHHHCCCCCCCEEHHHHHHCCHHHHEEEHHHCCHHHHHHHHHHHHCCCE
VLTTSFGIQSAVLLHMLHGLDGGSVVPVVWVDTGYLPAETYFYADQLTRQLGLDLKVVQS
EEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHH
TMSPARMEAIYGRLWETGSVKDLETYHRIRKVEPLEQALDDLRVHCWASGVRSDQTDYRR
HCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
SMAFLDLIRDRLSLRPLLDWTPKEVFYYMQEHQLPQHPLFEKGYSTVGDWHSSAPDGGGA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCC
SGRETRFGGLKQECGLHLPGVLGEGI
CCCCCCCCCCHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1463852 [H]