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The map label for this gene is mdtE [H]

Identifier: 33863884

GI number: 33863884

Start: 1718438

End: 1719565

Strand: Reverse

Name: mdtE [H]

Synonym: PMT1617

Alternate gene names: 33863884

Gene position: 1719565-1718438 (Counterclockwise)

Preceding gene: 33863886

Following gene: 33863883

Centisome position: 71.33

GC content: 46.63

Gene sequence:

>1128_bases
GTGAGCTGGAAACTTTCCATAATCAGGCTGTTGAACAAGTCGTTAGTGCCGAATCAGCAGCGCGCTCTTGTCGTTTTTAC
GGTGTTGTTACTTTGCGCCTGTGGTAAGGCGAAAATACCTTTCTCGCCGATTACCGTCAGCCAGACTCCTGTAACGACGG
CTCAATTCACGGACGATATCGATACGGTGAGCACCTTGGAGGCTAAGGAGGAGGTGCATCTTGCTGCACAAGCTTCTGGT
CGAATTATTGAGTTAAAGATTGATCAGGGTGATCAGGTTCAGCCTGGTCAGATGTTGGTTGTGCTCGATCAAGCTCAGAT
CCGTGCGGAATTGGCAGATTTCAAAGCTCAGGAGCAGAAGAACAAACTCAATTGGCAGCGATATGAATTTTTGGTCCCTC
AAGGAGCTGCTTCGGCATTGGATCGAGATGAATACAAGGCCCAGTACATCGCCTCTCGAGAAAAGGTAAAAGCCACAGAA
GCAACGCTTGCATATAGCAATTTGCGTTCTCCAATTTCAGGGATTGTGGCTGATGTTGATGTCAAGGTTGGAGATGTTAT
CCGTTCTGGTGATCCATTCACTAAATTGATCAGAAATAACAGGCTTTTTGCTCGAGTTGAGGTGCCTGCCACATTCTCTG
ATCGGATCAAGATTGGCTTGCCTGTCTTTCTCAACAAGACTGGATCGTCAGATGTGATGGCGACTGGTGAAATTAATTCT
GTGGGCCCGACTGTAAATAGAACTACCCAGGGCTTACTAGTGAAGGCAGCCTTTGAGAATGCTAATGGATCGCTGCGAAA
TGGCCAGCGCTTGCGAACGCGGGTTCAATTGGATACTAGAGAGGAGTTGTCTGTTCCGTTTGCTGCGGTAACACAAACTT
CCGGCCAGAGCTTTGTTTATCGAGTGGGAAGTTTCCAAGAGCTTGAAGATTTTTCTGGCAATATTTCTCTTGATAAACTT
CGTAAGTTACCCCCCTCCACACGTTTTGCTTTGCAGACCCCTGTGACGTTGGGAAAATTACAGAAGCAGCGCTATGCAGT
TACAAAAGGGCTCAAGCTTGGCGAGCAGGTGATCACAACAAATCTTTTGAAGTTGAGACATGGTATGCCTATTTCTGTTA
AAAATTGA

Upstream 100 bases:

>100_bases
GGCGCTTTAGCTCCTGATCTCCCTGATATGTGAACAGATTTTGATCCAATGAGCTCTGGCACTGGTAGACAATTCTTGCG
CTAGGGGGTGACTTGTTGTT

Downstream 100 bases:

>100_bases
GGCGAATAGATGTCAGCATCAAATAGCTTTATTACTCGACCTGTTTTAGCAACTGTTTGCAGTTTGTTGATTGTCATTGC
GGGACTGATATCGATCCCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSWKLSIIRLLNKSLVPNQQRALVVFTVLLLCACGKAKIPFSPITVSQTPVTTAQFTDDIDTVSTLEAKEEVHLAAQASG
RIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQKNKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATE
ATLAYSNLRSPISGIVADVDVKVGDVIRSGDPFTKLIRNNRLFARVEVPATFSDRIKIGLPVFLNKTGSSDVMATGEINS
VGPTVNRTTQGLLVKAAFENANGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVYRVGSFQELEDFSGNISLDKL
RKLPPSTRFALQTPVTLGKLQKQRYAVTKGLKLGEQVITTNLLKLRHGMPISVKN

Sequences:

>Translated_375_residues
MSWKLSIIRLLNKSLVPNQQRALVVFTVLLLCACGKAKIPFSPITVSQTPVTTAQFTDDIDTVSTLEAKEEVHLAAQASG
RIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQKNKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATE
ATLAYSNLRSPISGIVADVDVKVGDVIRSGDPFTKLIRNNRLFARVEVPATFSDRIKIGLPVFLNKTGSSDVMATGEINS
VGPTVNRTTQGLLVKAAFENANGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVYRVGSFQELEDFSGNISLDKL
RKLPPSTRFALQTPVTLGKLQKQRYAVTKGLKLGEQVITTNLLKLRHGMPISVKN
>Mature_374_residues
SWKLSIIRLLNKSLVPNQQRALVVFTVLLLCACGKAKIPFSPITVSQTPVTTAQFTDDIDTVSTLEAKEEVHLAAQASGR
IIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQKNKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATEA
TLAYSNLRSPISGIVADVDVKVGDVIRSGDPFTKLIRNNRLFARVEVPATFSDRIKIGLPVFLNKTGSSDVMATGEINSV
GPTVNRTTQGLLVKAAFENANGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVYRVGSFQELEDFSGNISLDKLR
KLPPSTRFALQTPVTLGKLQKQRYAVTKGLKLGEQVITTNLLKLRHGMPISVKN

Specific function: Part of a multidrug resistance efflux system that confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=393, Percent_Identity=24.1730279898219, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082036, Length=335, Percent_Identity=24.4776119402985, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41368; Mature: 41237

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKLSIIRLLNKSLVPNQQRALVVFTVLLLCACGKAKIPFSPITVSQTPVTTAQFTDDI
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHCCCCC
DTVSTLEAKEEVHLAAQASGRIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQK
HHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
NKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATEATLAYSNLRSPISGIVADVD
HCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECC
VKVGDVIRSGDPFTKLIRNNRLFARVEVPATFSDRIKIGLPVFLNKTGSSDVMATGEINS
EEHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEECCEEEEECCCCCCEEEECCCCC
VGPTVNRTTQGLLVKAAFENANGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVY
CCCCCCCCCCCEEEEEEECCCCCCCCCCHHHEEEEEECCHHHHCCCEEEEECCCCCEEEE
RVGSFQELEDFSGNISLDKLRKLPPSTRFALQTPVTLGKLQKQRYAVTKGLKLGEQVITT
ECCCHHHHHHCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLLKLRHGMPISVKN
HHHHHHCCCCEEECC
>Mature Secondary Structure 
SWKLSIIRLLNKSLVPNQQRALVVFTVLLLCACGKAKIPFSPITVSQTPVTTAQFTDDI
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHCCCCC
DTVSTLEAKEEVHLAAQASGRIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQK
HHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
NKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATEATLAYSNLRSPISGIVADVD
HCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECC
VKVGDVIRSGDPFTKLIRNNRLFARVEVPATFSDRIKIGLPVFLNKTGSSDVMATGEINS
EEHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEECCEEEEECCCCCCEEEECCCCC
VGPTVNRTTQGLLVKAAFENANGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVY
CCCCCCCCCCCEEEEEEECCCCCCCCCCHHHEEEEEECCHHHHCCCEEEEECCCCCEEEE
RVGSFQELEDFSGNISLDKLRKLPPSTRFALQTPVTLGKLQKQRYAVTKGLKLGEQVITT
ECCCHHHHHHCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLLKLRHGMPISVKN
HHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]