Click here to switch to the map view.

The map label for this gene is mexB [H]

Identifier: 33863883

GI number: 33863883

Start: 1714991

End: 1718428

Strand: Reverse

Name: mexB [H]

Synonym: PMT1616

Alternate gene names: 33863883

Gene position: 1718428-1714991 (Counterclockwise)

Preceding gene: 33863884

Following gene: 33863882

Centisome position: 71.28

GC content: 45.61

Gene sequence:

>3438_bases
ATGTCAGCATCAAATAGCTTTATTACTCGACCTGTTTTAGCAACTGTTTGCAGTTTGTTGATTGTCATTGCGGGACTGAT
ATCGATCCCTATTTTGCCAGTTGAAATGCTTCCGGATATAGCTCCGCCAACAGTAAAAGTAAATTCAATTTACACCGGTG
CCGATGCTGAATCGGTTGAACAGGGTGTGACCAGTGTGCTGGAGCAGCAGATTAATGGTGTGGAGAATATGGACTATTTA
ACTTCCTCAAGCTCGGCTGATGGGGTTAGCTCGATTGCTGTTGCGTTCGAAAGTGGTAGTAATAGCGACATTAATCAAGT
TAATGTTCAGAACAGGGTTGCGCTGGCAGAGCCACAGTTGCCGGAAGCAGTGCGCAAGGCAGGGGTGAGTGTTAACAAGG
CTTCCAATTCCATCTTGCTTCTTTATAATTTTGTTAGCGAAGATCCAAGCAATATTGAATATAGTGTAGAAACGATTAGT
GGGCTGCTAGATCTGGGCCTAACGGACGAAGTTAAGCGGGTTAAGGGAGTCGGTGAAGTGACCTACTTTGGTAACCGTAA
GGTTGCTTTTAGGCTTTGGCTGGACAATGAAAAGCTTGAGGTTTTTGGCCTGACTTCAGCGGATGTAATGGGGGCGATTG
AAAGCCAGAACCGTTTGGTTCCTGCTGGGAATGTAGGAGGTGAACCATCTGCAGAAGGCCAGATATTTACTTTTCCTGTG
CAATTAAATGGCCGCCTTGTGAGCATTGGAGACTTTGAAAATATGGTCGTTAGGACTACAGAGGATGGCGGATTAGTGAG
GTTCAGCGATGTCGGTCATGTTGTGCTTGGTGGTGAAAGCTATTCCAACAGCGCTACAGATTTGCAGGGAGTACCTTCTG
TGAGTATGGCTGTTTATCAATTGAGTGGCAGTAATGCTCTAGAGGTATCCAATGGAGTCAAAGATGTTCTCGAAGAATTT
ACCGCCAAAATGCCTGTCGGCATGAAGATTGAAAAAATCTATGATAATACAGACTTTATTAATGCATCAATTAATGGAGT
GACCAATTCACTTAGAGATGCGATCATTTTGGTGGTTCTTATTCTGTTTGTATTTTTACAGAATTGGAAAGCTACTTTGG
TGCCTGGTATTGCCATCCCTGTTGCACTTCTAGGCACATTCTCTCTGGTTTTATGGTTTGGCTTCTCGCTCAACCAGCTT
ACTTTATTTGGATTGGTTCTCGCTACAGGGTTAGTGGTTGATGATGCAATCACAGTGATTGAAGATACCTCAACCAAGCA
GTCATTAGGGATGACTGCTTTGGAAGCTGCGAAGTCAACAATGGATGAGCTTTTCTCTGCAGTTATTGCTACATCCTTGG
TTCTTTTCTCAGTATTTTTGCCAGTGTTATTTTTTCCTGGCGCTACGGGTTCGATCTACAAGCAGTTTGCAGCAACGATT
ATTTTCGCTATCGCGATTTCTACCTTTAATGCTTTAACTTTTTCCCCCATGCTTTCTGCCTTGCTTTTGGGCCGGGAAGG
CACAGCTCCGGGCCGCAATGCATATGCAATTTCTGGTGCAGTCATTGGGTTTATATACGGACTATTAGTTGTTGGCGGTG
GTGCGGCGCTGGCCTTGATCCTTACAGCAATGGCTGCAATTCTTGGCTTTGTGCTGTCTCGCTTGACTGGCCGTTCGTTG
AGGCTGCCATTCTCTGTTGCAGGGGCTGTGATTGGTCTTTTCATCGCAGGAGTTTCAAGTCCCTTGCCAGTCGTTTTATT
CGCTGGGCTTGGCTTGACCTTGGGTTGGTATACACCATGGATTTTTAGTCATTTCAATCGCATTTATTCCGTCTTTGAGC
TGCGCTATGCCGATCTGCTCGAGTGGGTTCTTGGCCGCCGTTCTCTTGTGATGGGAATTCTTGCGGTAGGGGTTCTGCTG
ACCGGTGTTGCTTTTACTGCGATTCCAAGTGGATTTGTTCCTATTGAAGATCAGGGCTATGCCATCGGCGTGTTGCAGGC
CCCAGAAGGCGTGTCGACTCAGGTCACCGAGAAGATTAATCAGCAAGTTGCTGAGATATTGCGCAGCGAATCCGATATCA
CTTCAGCAGCAATTTTTAGTGGAGCAAGTTTTGATGGCAATAGCCCTAATAAAGGATTATTTTTTATTGGGATGCGTAAT
TGGGATGAGAGGAAAAATCGTGATCAATCCGCCGATGCAATTGTTGGACGGCTCAACCAGAAGTTCTTTGGGGCTATTGA
TGGCGCGAGGATTTTTGTTGTAGAGCCACCTGCGATTCCTGGATACGGCATTGGCAGTGGATTTGAGTTCCAATTACTTG
ACAAGAGTGGAGGTGCTTATGGCTTAAACAACTTCTTTGCCTCAGCTGGTCAAATTATTCAGCAGGCGAAAGCAAATCCA
ATGTTGAGCAGTGTAAGGACTTTATTCTCGCCTGAATCTCCGCAGCTACGAGTTGAGGTCGATAGGGACATTATGGCCTC
TCTTGATGTTGACTTCAGCTCTGCAATGCGTGTGTTTAGCGCTAATTTTGCAGGCGCCTATGTTAATGATACCTTCCAGG
AAGGTAAGGTTCGTCGTGTTTATGTTCAGGCCGATGAATTGGGTCGGTCTGCACCTGAAAAGCTATCTTCAATTTACGTT
AAGAATCGGGTGGGTGAGCAGATTCAGCTCTCGGAATTTTTAACAGTTGAACCTTCTGTTGGGCCAAGTGTGATCTCTCA
CTTTAACCTTTACAGATCGATAAAAATAGAAGGATCACCTGCTGCTGGTAAGAGCTCGGGGCAGGCAATTAATGGTATGA
AGGAGCTTTTTGCAGCTCAGAATCTTAAGAGCCTCGGATTTGATTGGACAGGGATATCTCGAGAGGAAGTAAAAGCTGGT
GCACTAGCTGTTGTGATTTTTGCATTGGGAATTTTGGTGGTTTATCTCGTGCTTGCAGCTCAATACGAGAGTTATACAGA
CCCTCTGATTATTTTAATGACAGTTCCTACTGCAATGCTTGGAGCCTTGTTTTTTCTGGCATTGCGTGGAGAGGTTCTCA
ACATTTATGCACAGGTTGGCCTTGTGATGTTGATTGGTCTAGCTGCTAAAAATGGGATCTTGATTGTTGATTTGGCTAAT
CAACGCATGGCTGAGGGAGTTTCGGCCCTTGAAGCAGCAAGGCAGGCAGCCAAGTCGAGACTTAGGCCCATCATTATGAC
TGCTATTTCGTCTCTTTTTGGCTTTATGCCGTTGGTCTTGGCTAGCGGAGCAGGAGCCCGCAGCCAAGCTTCTCTTGGCA
CGGTTGTATTCGGTGGCCTTTTGGTTGCTACTTTCCTTTCGCTGTTTGTTGTGCCTGTCTTTTACGTCGCTGTTAAAGCT
CTTGTAGGAACCTTTAGTGATACGGAACAAGGCAACACCAATTTACTTAATTCGGGAGACCCCTTTGGGCAGGGATAA

Upstream 100 bases:

>100_bases
AGTTACAAAAGGGCTCAAGCTTGGCGAGCAGGTGATCACAACAAATCTTTTGAAGTTGAGACATGGTATGCCTATTTCTG
TTAAAAATTGAGGCGAATAG

Downstream 100 bases:

>100_bases
ACCAATGAACCGCTCTCGCTCAATAAGAAATAAGGCCTTCAGCGGTACAAGGGTATTGATAGCGCTGCTGGTGGGGTTCT
TGCTCGGAGGTTTTGTTGCC

Product: RND family multidrug efflux transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Multidrug-efflux transporter MexB [H]

Number of amino acids: Translated: 1145; Mature: 1144

Protein sequence:

>1145_residues
MSASNSFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVEQGVTSVLEQQINGVENMDYL
TSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQLPEAVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETIS
GLLDLGLTDEVKRVKGVGEVTYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGNVGGEPSAEGQIFTFPV
QLNGRLVSIGDFENMVVRTTEDGGLVRFSDVGHVVLGGESYSNSATDLQGVPSVSMAVYQLSGSNALEVSNGVKDVLEEF
TAKMPVGMKIEKIYDNTDFINASINGVTNSLRDAIILVVLILFVFLQNWKATLVPGIAIPVALLGTFSLVLWFGFSLNQL
TLFGLVLATGLVVDDAITVIEDTSTKQSLGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNAYAISGAVIGFIYGLLVVGGGAALALILTAMAAILGFVLSRLTGRSL
RLPFSVAGAVIGLFIAGVSSPLPVVLFAGLGLTLGWYTPWIFSHFNRIYSVFELRYADLLEWVLGRRSLVMGILAVGVLL
TGVAFTAIPSGFVPIEDQGYAIGVLQAPEGVSTQVTEKINQQVAEILRSESDITSAAIFSGASFDGNSPNKGLFFIGMRN
WDERKNRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAYGLNNFFASAGQIIQQAKANP
MLSSVRTLFSPESPQLRVEVDRDIMASLDVDFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSAPEKLSSIYV
KNRVGEQIQLSEFLTVEPSVGPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLKSLGFDWTGISREEVKAG
ALAVVIFALGILVVYLVLAAQYESYTDPLIILMTVPTAMLGALFFLALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLAN
QRMAEGVSALEAARQAAKSRLRPIIMTAISSLFGFMPLVLASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVAVKA
LVGTFSDTEQGNTNLLNSGDPFGQG

Sequences:

>Translated_1145_residues
MSASNSFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVEQGVTSVLEQQINGVENMDYL
TSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQLPEAVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETIS
GLLDLGLTDEVKRVKGVGEVTYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGNVGGEPSAEGQIFTFPV
QLNGRLVSIGDFENMVVRTTEDGGLVRFSDVGHVVLGGESYSNSATDLQGVPSVSMAVYQLSGSNALEVSNGVKDVLEEF
TAKMPVGMKIEKIYDNTDFINASINGVTNSLRDAIILVVLILFVFLQNWKATLVPGIAIPVALLGTFSLVLWFGFSLNQL
TLFGLVLATGLVVDDAITVIEDTSTKQSLGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNAYAISGAVIGFIYGLLVVGGGAALALILTAMAAILGFVLSRLTGRSL
RLPFSVAGAVIGLFIAGVSSPLPVVLFAGLGLTLGWYTPWIFSHFNRIYSVFELRYADLLEWVLGRRSLVMGILAVGVLL
TGVAFTAIPSGFVPIEDQGYAIGVLQAPEGVSTQVTEKINQQVAEILRSESDITSAAIFSGASFDGNSPNKGLFFIGMRN
WDERKNRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAYGLNNFFASAGQIIQQAKANP
MLSSVRTLFSPESPQLRVEVDRDIMASLDVDFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSAPEKLSSIYV
KNRVGEQIQLSEFLTVEPSVGPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLKSLGFDWTGISREEVKAG
ALAVVIFALGILVVYLVLAAQYESYTDPLIILMTVPTAMLGALFFLALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLAN
QRMAEGVSALEAARQAAKSRLRPIIMTAISSLFGFMPLVLASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVAVKA
LVGTFSDTEQGNTNLLNSGDPFGQG
>Mature_1144_residues
SASNSFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVEQGVTSVLEQQINGVENMDYLT
SSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQLPEAVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETISG
LLDLGLTDEVKRVKGVGEVTYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGNVGGEPSAEGQIFTFPVQ
LNGRLVSIGDFENMVVRTTEDGGLVRFSDVGHVVLGGESYSNSATDLQGVPSVSMAVYQLSGSNALEVSNGVKDVLEEFT
AKMPVGMKIEKIYDNTDFINASINGVTNSLRDAIILVVLILFVFLQNWKATLVPGIAIPVALLGTFSLVLWFGFSLNQLT
LFGLVLATGLVVDDAITVIEDTSTKQSLGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATII
FAIAISTFNALTFSPMLSALLLGREGTAPGRNAYAISGAVIGFIYGLLVVGGGAALALILTAMAAILGFVLSRLTGRSLR
LPFSVAGAVIGLFIAGVSSPLPVVLFAGLGLTLGWYTPWIFSHFNRIYSVFELRYADLLEWVLGRRSLVMGILAVGVLLT
GVAFTAIPSGFVPIEDQGYAIGVLQAPEGVSTQVTEKINQQVAEILRSESDITSAAIFSGASFDGNSPNKGLFFIGMRNW
DERKNRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAYGLNNFFASAGQIIQQAKANPM
LSSVRTLFSPESPQLRVEVDRDIMASLDVDFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSAPEKLSSIYVK
NRVGEQIQLSEFLTVEPSVGPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLKSLGFDWTGISREEVKAGA
LAVVIFALGILVVYLVLAAQYESYTDPLIILMTVPTAMLGALFFLALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLANQ
RMAEGVSALEAARQAAKSRLRPIIMTAISSLFGFMPLVLASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVAVKAL
VGTFSDTEQGNTNLLNSGDPFGQG

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the MexB

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1789666, Length=501, Percent_Identity=40.7185628742515, Blast_Score=387, Evalue=1e-108,
Organism=Escherichia coli, GI1786667, Length=500, Percent_Identity=41, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1789930, Length=501, Percent_Identity=40.7185628742515, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI1788814, Length=515, Percent_Identity=38.0582524271845, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1788390, Length=511, Percent_Identity=31.3111545988258, Blast_Score=231, Evalue=3e-61,
Organism=Escherichia coli, GI1788391, Length=533, Percent_Identity=29.2682926829268, Blast_Score=192, Evalue=2e-49,
Organism=Escherichia coli, GI1786788, Length=545, Percent_Identity=26.0550458715596, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 121566; Mature: 121434

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASNSFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEEECCCHHHHH
QGVTSVLEQQINGVENMDYLTSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQL
HHHHHHHHHHHCCCCCCHHHCCCCCCCCHHEEEEEEECCCCCCCCEECCCCCEEECCCCC
PEAVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETISGLLDLGLTDEVKRVKGVGEV
HHHHHHCCCEEECCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCHHHHHHCCCCCE
TYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGNVGGEPSAEGQIFTFPV
EEECCCEEEEEEEECCCCEEEEECCHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEEE
QLNGRLVSIGDFENMVVRTTEDGGLVRFSDVGHVVLGGESYSNSATDLQGVPSVSMAVYQ
EECCEEEEECCCCCEEEEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCEEEEEE
LSGSNALEVSNGVKDVLEEFTAKMPVGMKIEKIYDNTDFINASINGVTNSLRDAIILVVL
ECCCCCEEHHCCHHHHHHHHHHCCCCCCEEHEEECCCCEEECCHHHHHHHHHHHHHHHHH
ILFVFLQNWKATLVPGIAIPVALLGTFSLVLWFGFSLNQLTLFGLVLATGLVVDDAITVI
HHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEE
EDTSTKQSLGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
ECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNAYAISGAVIGFIYGLLVVGGGAALALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHH
LTAMAAILGFVLSRLTGRSLRLPFSVAGAVIGLFIAGVSSPLPVVLFAGLGLTLGWYTPW
HHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IFSHFNRIYSVFELRYADLLEWVLGRRSLVMGILAVGVLLTGVAFTAIPSGFVPIEDQGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCE
AIGVLQAPEGVSTQVTEKINQQVAEILRSESDITSAAIFSGASFDGNSPNKGLFFIGMRN
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECC
WDERKNRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAY
CHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
GLNNFFASAGQIIQQAKANPMLSSVRTLFSPESPQLRVEVDRDIMASLDVDFSSAMRVFS
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHCCCCHHHHHHHHH
ANFAGAYVNDTFQEGKVRRVYVQADELGRSAPEKLSSIYVKNRVGEQIQLSEFLTVEPSV
CCCCCCHHCCHHHCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCCEEHHHEEEECCCC
GPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLKSLGFDWTGISREEVKAG
CHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ALAVVIFALGILVVYLVLAAQYESYTDPLIILMTVPTAMLGALFFLALRGEVLNIYAQVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVMLIGLAAKNGILIVDLANQRMAEGVSALEAARQAAKSRLRPIIMTAISSLFGFMPLVL
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVAVKALVGTFSDTEQGNTNLLNSGD
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PFGQG
CCCCC
>Mature Secondary Structure 
SASNSFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEEECCCHHHHH
QGVTSVLEQQINGVENMDYLTSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQL
HHHHHHHHHHHCCCCCCHHHCCCCCCCCHHEEEEEEECCCCCCCCEECCCCCEEECCCCC
PEAVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETISGLLDLGLTDEVKRVKGVGEV
HHHHHHCCCEEECCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCHHHHHHCCCCCE
TYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGNVGGEPSAEGQIFTFPV
EEECCCEEEEEEEECCCCEEEEECCHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEEE
QLNGRLVSIGDFENMVVRTTEDGGLVRFSDVGHVVLGGESYSNSATDLQGVPSVSMAVYQ
EECCEEEEECCCCCEEEEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCEEEEEE
LSGSNALEVSNGVKDVLEEFTAKMPVGMKIEKIYDNTDFINASINGVTNSLRDAIILVVL
ECCCCCEEHHCCHHHHHHHHHHCCCCCCEEHEEECCCCEEECCHHHHHHHHHHHHHHHHH
ILFVFLQNWKATLVPGIAIPVALLGTFSLVLWFGFSLNQLTLFGLVLATGLVVDDAITVI
HHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEE
EDTSTKQSLGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
ECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNAYAISGAVIGFIYGLLVVGGGAALALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHH
LTAMAAILGFVLSRLTGRSLRLPFSVAGAVIGLFIAGVSSPLPVVLFAGLGLTLGWYTPW
HHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IFSHFNRIYSVFELRYADLLEWVLGRRSLVMGILAVGVLLTGVAFTAIPSGFVPIEDQGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCE
AIGVLQAPEGVSTQVTEKINQQVAEILRSESDITSAAIFSGASFDGNSPNKGLFFIGMRN
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCEEEEEECC
WDERKNRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAY
CHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
GLNNFFASAGQIIQQAKANPMLSSVRTLFSPESPQLRVEVDRDIMASLDVDFSSAMRVFS
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHCCCCHHHHHHHHH
ANFAGAYVNDTFQEGKVRRVYVQADELGRSAPEKLSSIYVKNRVGEQIQLSEFLTVEPSV
CCCCCCHHCCHHHCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHCCCCEEHHHEEEECCCC
GPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLKSLGFDWTGISREEVKAG
CHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ALAVVIFALGILVVYLVLAAQYESYTDPLIILMTVPTAMLGALFFLALRGEVLNIYAQVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVMLIGLAAKNGILIVDLANQRMAEGVSALEAARQAAKSRLRPIIMTAISSLFGFMPLVL
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVAVKALVGTFSDTEQGNTNLLNSGD
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PFGQG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7968531; 10984043; 9989496; 8226684; 8540696; 9603892; 10187844 [H]