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The map label for this gene is rpoC1 [H]

Identifier: 33863773

GI number: 33863773

Start: 1591304

End: 1593208

Strand: Reverse

Name: rpoC1 [H]

Synonym: PMT1506

Alternate gene names: 33863773

Gene position: 1593208-1591304 (Counterclockwise)

Preceding gene: 33863774

Following gene: 33863772

Centisome position: 66.08

GC content: 50.13

Gene sequence:

>1905_bases
ATGACTAACAGCAACCTCCGTACAGAGAACCACTTCGACTACGTCAAGATCACACTTGCTTCACCAGATCGGGTGATGGA
GTGGGGTCAGCGGACACTTCCTAATGGGCAGGTAGTGGGTGAAGTGACGAAGCCGGAGACGATTAATTACCGCACCCTGA
AGCCTGAGATGGACGGGCTCTTTTGCGAGAAGATCTTCGGCCCTTCAAAGGATTGGGAGTGTCATTGCGGGAAATATAAG
CGGGTTCGACACCGTGGCATTGTCTGTGAGCGTTGTGGCGTGGAGGTCACTGAAAGTCGGGTTCGGCGTCATCGCATGGG
CTTCATCAAGTTGGCAGCTCCTGTCTCCCACGTTTGGTATTTGAAAGGGATACCTAGTTATGTGGCGATCTTGTTAGATA
TGCCACTACGTGATGTTGAGCAGATTGTTTACTTCAACTGTTATGTCGTGCTTGATCCTGGCGATCATAAGGAACTCAAG
TATAAGCAGTTACTTACTGAGGATGAGTGGTTAGAGATTGAAGATGAGATCTATGCAGAAGATTCCACGATTGAGAATGA
GCCGATGGTTGGCATCGGTGCTGAAGCTCTAAAGCAATTGCTAGAAGATTTAGATTTGCCTGATGTAGCTGAACAGTTGC
GAGAGGAAATCTCATCTAGCAAGGGTCAAAAGCGGGCCAAGTTAATTAAGCGTTTGCGTGTGATTGATAATTTCATTGCT
ACCAATGCAAGGCCTGAGTGGATGGTGCTGGATGCGATTCCAGTCATTCCCCCGGATCTTCGTCCAATGGTCCAATTGGA
TGGCGGACGTTTCGCGACCTCCGACCTGAACGACCTTTACCGTCGGGTGATTAATCGCAACAACCGTCTTGCTCGACTTC
AGGAAATTCTGGCCCCTGAAATTATCGTCAGAAATGAGAAGCGGATGCTTCAGGAGGCAGTGGATGCTCTGATCGATAAC
GGTCGTCGCGGCAGAACTGTTGTTGGTGCTAACAATCGTCCGTTGAAGTCCCTCAGCGACATCATTGAGGGCAAGCAGGG
TCGCTTCCGTCAGAACTTGCTTGGTAAGAGGGTTGATTACTCAGGTCGTTCCGTGATCGTGGTGGGCCCCAAGCTGAAGA
TGCATCAGTGCGGCTTGCCTAAAGAGATGGCGATTGAGTTGTTTCAACCGTTCGTGATCCACCGTCTGATTCGTCAGAAC
ATTGTCAACAACATCAAGGCTGCAAAGAAGTTGATTCAGCGTGCTGATGATGAGGTGATGCAGGTGCTGCAAGAGGTCAT
CGAGGGGCATCCGATTCTGTTAAACCGCGCTCCAACTCTTCATCGTCTCGGTATTCAGGCTTTCGAGCCAAAGCTGGTCG
ATGGTCGTGCGATTCAGTTACACCCGTTGGTCTGTCCTGCTTTTAATGCCGACTTCGATGGTGACCAGATGGCGGTTCAT
GTGCCGCTCGCGATTGAGTCTCAAACGGAGGCACGCATGTTGATGTTGGCCAGTAACAACATCCTTTCGCCTGCCACCGG
TGATCCGATCATCACTCCCTCGCAGGACATGGTGCTTGGTTCTTATTACCTCACGGCGCTCAAGCCTGGAGCTTCTGTGC
CTGAGTTTGGCGATCAATCCAGAACCTATTCAGGTTTAGAGGACGTCATTCATGCGTTTGAAGATAAAAGGATCTTGCTA
CATGACTGGGTTTGGGTTCGTTTTAACGGTGAGGTTGAGGACGAAGATGAGATAGAAGAGCCCATCAAAGCTGAACTACT
CAGCGATGGAACTCGCATTGAGCAGTGGACTTATCGCCGAGATCGTTTCGACGAAGACGGAGCATTGATCAGTCGCTACA
TCCTTACAACAGTGGGCCGCGTGGTGATGAATTACACAATTATTGATGCGGTGGCCGTCGCCTGA

Upstream 100 bases:

>100_bases
AGTCGACCCACTTACGAATCCCTTGGAGTAGCGGATTACGACGAAGATTAACGGCCTTACCTAACTGCTTTTCGTTTCCC
AAACTGTTTGCGATTCGTTC

Downstream 100 bases:

>100_bases
GTTACTCCAATACCAGCTTTCTTCCCTGACCTGATTCACGTGTAGCCATGACCTCAACCTCCCCGAAATCCCGCAAGCCT
TCGACCAAGACCACCAAGTC

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPMVGIGAEALKQLLEDLDLPDVAEQLREEISSSKGQKRAKLIKRLRVIDNFIA
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQRADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVH
VPLAIESQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTALKPGASVPEFGDQSRTYSGLEDVIHAFEDKRILL
HDWVWVRFNGEVEDEDEIEEPIKAELLSDGTRIEQWTYRRDRFDEDGALISRYILTTVGRVVMNYTIIDAVAVA

Sequences:

>Translated_634_residues
MTNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYK
RVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELK
YKQLLTEDEWLEIEDEIYAEDSTIENEPMVGIGAEALKQLLEDLDLPDVAEQLREEISSSKGQKRAKLIKRLRVIDNFIA
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDN
GRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQN
IVNNIKAAKKLIQRADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVH
VPLAIESQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTALKPGASVPEFGDQSRTYSGLEDVIHAFEDKRILL
HDWVWVRFNGEVEDEDEIEEPIKAELLSDGTRIEQWTYRRDRFDEDGALISRYILTTVGRVVMNYTIIDAVAVA
>Mature_633_residues
TNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKR
VRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKY
KQLLTEDEWLEIEDEIYAEDSTIENEPMVGIGAEALKQLLEDLDLPDVAEQLREEISSSKGQKRAKLIKRLRVIDNFIAT
NARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNG
RRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNI
VNNIKAAKKLIQRADDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVHV
PLAIESQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTALKPGASVPEFGDQSRTYSGLEDVIHAFEDKRILLH
DWVWVRFNGEVEDEDEIEEPIKAELLSDGTRIEQWTYRRDRFDEDGALISRYILTTVGRVVMNYTIIDAVAVA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=302, Percent_Identity=31.1258278145695, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI39725938, Length=321, Percent_Identity=28.3489096573209, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=30.3571428571429, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI2367335, Length=523, Percent_Identity=61.7590822179732, Blast_Score=696, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=305, Percent_Identity=31.4754098360656, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25145495, Length=323, Percent_Identity=30.6501547987616, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71998295, Length=336, Percent_Identity=24.1071428571429, Blast_Score=93, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320061, Length=498, Percent_Identity=27.710843373494, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324690, Length=227, Percent_Identity=37.8854625550661, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17530899, Length=309, Percent_Identity=29.7734627831715, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360912, Length=503, Percent_Identity=26.441351888668, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI17647875, Length=337, Percent_Identity=27.893175074184, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 72278; Mature: 72147

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHH
LKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HHCHHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPMVGIGAEALKQLLEDLDLPDVAEQLREEISSSKGQKRAKLIKRLRVIDNFIA
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQRADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCHHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEE
VPLAIESQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTALKPGASVPEFGDQS
EEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCCCCCCCCCCCC
RTYSGLEDVIHAFEDKRILLHDWVWVRFNGEVEDEDEIEEPIKAELLSDGTRIEQWTYRR
CHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
DRFDEDGALISRYILTTVGRVVMNYTIIDAVAVA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNSNLRTENHFDYVKITLASPDRVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGL
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCH
FCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWY
HHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHH
LKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAE
HHCHHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCCCCCEEECHHHCCC
DSTIENEPMVGIGAEALKQLLEDLDLPDVAEQLREEISSSKGQKRAKLIKRLRVIDNFIA
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TNARPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPE
CCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCH
IIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDY
HEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQRADDEVM
CCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVH
HHHHHHHCCCCEEEECCCCHHHHCHHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEE
VPLAIESQTEARMLMLASNNILSPATGDPIITPSQDMVLGSYYLTALKPGASVPEFGDQS
EEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCCCCCCCCCCCC
RTYSGLEDVIHAFEDKRILLHDWVWVRFNGEVEDEDEIEEPIKAELLSDGTRIEQWTYRR
CHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
DRFDEDGALISRYILTTVGRVVMNYTIIDAVAVA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA