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The map label for this gene is sglT [H]

Identifier: 33863769

GI number: 33863769

Start: 1584042

End: 1585811

Strand: Reverse

Name: sglT [H]

Synonym: PMT1502

Alternate gene names: 33863769

Gene position: 1585811-1584042 (Counterclockwise)

Preceding gene: 33863770

Following gene: 33863768

Centisome position: 65.78

GC content: 56.1

Gene sequence:

>1770_bases
ATGGCTGCCATTGATTGGATGATCCTCGTTGGTTATCTCGCCATCACTCTCGTGATTGGACTTTGGTTGTCTCGTCGCAA
TCGAAGTGAGGATGATTACTTTGTTGCGGGACGTCGACTCAGTGGTTGGTTGGCTGGGGCTTCGATGGCCGCAACGACAT
TTTCGATTGATACCCCTCTTTATGTAGCCGGTCTGGTTGGCACACGAGGATTGGCCGGCAATTGGGAATGGTGGAGCTTC
GGCCTGGCGCATGTCGCCATGGCAGTTGTCTTTGCTCCGCTCTGGCGACGGAGTGGGGTGCTGACCGATGCTGCATTCAC
CGAGCTGCGTTATGGCGGAGCGCCTGCTGCCTGGCTGCGTGGGATTAAAGCATTTTTGCTCGCACTGCCGGTGAATTGCA
TCGGTATCGGCTATGCCTTCCTGGCCATGCGCAAGGTCGTAGAAGCCCTGGGCATCGTGTCTGGCAGCCCTGTGGAAGTG
CTTGGCGGCACCCCTGACACTGTTGTGCTGTTGGCAGTCGTGGCTGTGATGGTGCTTGTTTACACCGTTGCTGGGGGCCT
CTGGGCTGTCGTGATCACCGATTTCGTGCAGTTGCTGTTGGCTCTTTTGGGAGCGGTTGCGGTGGCGTGGGCCGCCGTTC
ATGCAGCCGGAGGGATGGACGCCATGCTCGATCAACTGAGGGGGTTAGAGCGACCTGAACTGCTGGCGATTGTGCCTTGG
CAATGGAATGGTGATGGCTTTGATTGGATTGGTGGCGCCGAGATCAGTGTGGCCACATTCCTGTCTTATCTCACTGTCCA
ATGGTGGAGTTTCCGTCGCAGTGACGGTGGTGGTGAGTTCATTCAGCGAATGTTGGCCACGCGGGACGAGCGTCAGGCTC
AACTGGCTGGCTGGGTGTTTCTGGTGGTCAACTATCTGGTGCGCAGTTGGTTGTGGGTTTTGGTTGCTCTTGCCGCTTTA
GTGCTCTTGCCAGCTCAGGCCGACTGGGAACTCAGTTACCCAACCTTGGCTGTGACCTACCTACCGCCAGTGGTGCTTGG
TCTTGTAGTGGTCTCTCTGGTGGCGGCTTTCATGAGTACGGTCAGTACCGCAGTGAACTGGGGTGCTAGCTATCTCACCC
ACGATCTTTACCAGCGTTTTATAAGGCCGGATGCTGATCAGAGAGAGCTGTTGCTGGTTGGTCAATTCACCAGTGTTTTG
CTGCTAGTTCTCGGGGTGATCACCGCATTAATTAGCGACAGCATCGGCACAGTGTTTCGTCTGGTGATTGCTATTGGTAC
CGGGCCCGGAGTGGTGCTTGTGCTGCGTTGGTTCTGGTGGCGCATCAATGCTGCTGCCGAATTGGCGGCGATGGTTTGTG
GTTTTGTGGTGGGCCTTTGTACATCCGTTATGCCCTTGGTGACAATTCCTGATTACGGCACCAGGTTGATGATCACTACA
GCGATTACTGCTGTGGTCTGGGTTGTAGTGATGCTAGTGACTCCGCCTGAATCGCCGCAAGTGCTCGAGCGCTTTGTGAA
CCAGGTGCAGCCACCAGGCCCAGGCTGGAGTCGCTTGCGTCAACGCCTGGATATAACACCGGTGGATTCCCTCGGAAGTT
TGTGTTTGCGCTTCATTCTTAGTGTCGGTGTTCTGTTTGGCGGCCTGCTCGGCACTGGCGCGTTTTTGTTACATCAGCAG
CTAGGCGGTTGGATCGGTTTGGTGGTCACCGTGATCTGTGTGCTGCCTTTAACCCGTGGTTGGCTGCGCAGTCGGATAGG
CGTCGCATGA

Upstream 100 bases:

>100_bases
GCTGGATCAGAATGCCGCCTGTGGTCAGCTCCGCCGCCAGCACGCTGCCACCGGCTGAGATGGACTAGCTGAGTCACACT
GCGATCAACCGCCTAAGGAT

Downstream 100 bases:

>100_bases
TCTCCAACAAGGTCTTGGCTTGGGAGGCAGAATGAACGAAAGTCTTCGCAAGCATTGAATTTCATACGTTCCACCGTGTT
GCCTGCTCTGATTGTGGCTT

Product: sodium/solute symporter family protein glucose transporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MAAIDWMILVGYLAITLVIGLWLSRRNRSEDDYFVAGRRLSGWLAGASMAATTFSIDTPLYVAGLVGTRGLAGNWEWWSF
GLAHVAMAVVFAPLWRRSGVLTDAAFTELRYGGAPAAWLRGIKAFLLALPVNCIGIGYAFLAMRKVVEALGIVSGSPVEV
LGGTPDTVVLLAVVAVMVLVYTVAGGLWAVVITDFVQLLLALLGAVAVAWAAVHAAGGMDAMLDQLRGLERPELLAIVPW
QWNGDGFDWIGGAEISVATFLSYLTVQWWSFRRSDGGGEFIQRMLATRDERQAQLAGWVFLVVNYLVRSWLWVLVALAAL
VLLPAQADWELSYPTLAVTYLPPVVLGLVVVSLVAAFMSTVSTAVNWGASYLTHDLYQRFIRPDADQRELLLVGQFTSVL
LLVLGVITALISDSIGTVFRLVIAIGTGPGVVLVLRWFWWRINAAAELAAMVCGFVVGLCTSVMPLVTIPDYGTRLMITT
AITAVVWVVVMLVTPPESPQVLERFVNQVQPPGPGWSRLRQRLDITPVDSLGSLCLRFILSVGVLFGGLLGTGAFLLHQQ
LGGWIGLVVTVICVLPLTRGWLRSRIGVA

Sequences:

>Translated_589_residues
MAAIDWMILVGYLAITLVIGLWLSRRNRSEDDYFVAGRRLSGWLAGASMAATTFSIDTPLYVAGLVGTRGLAGNWEWWSF
GLAHVAMAVVFAPLWRRSGVLTDAAFTELRYGGAPAAWLRGIKAFLLALPVNCIGIGYAFLAMRKVVEALGIVSGSPVEV
LGGTPDTVVLLAVVAVMVLVYTVAGGLWAVVITDFVQLLLALLGAVAVAWAAVHAAGGMDAMLDQLRGLERPELLAIVPW
QWNGDGFDWIGGAEISVATFLSYLTVQWWSFRRSDGGGEFIQRMLATRDERQAQLAGWVFLVVNYLVRSWLWVLVALAAL
VLLPAQADWELSYPTLAVTYLPPVVLGLVVVSLVAAFMSTVSTAVNWGASYLTHDLYQRFIRPDADQRELLLVGQFTSVL
LLVLGVITALISDSIGTVFRLVIAIGTGPGVVLVLRWFWWRINAAAELAAMVCGFVVGLCTSVMPLVTIPDYGTRLMITT
AITAVVWVVVMLVTPPESPQVLERFVNQVQPPGPGWSRLRQRLDITPVDSLGSLCLRFILSVGVLFGGLLGTGAFLLHQQ
LGGWIGLVVTVICVLPLTRGWLRSRIGVA
>Mature_588_residues
AAIDWMILVGYLAITLVIGLWLSRRNRSEDDYFVAGRRLSGWLAGASMAATTFSIDTPLYVAGLVGTRGLAGNWEWWSFG
LAHVAMAVVFAPLWRRSGVLTDAAFTELRYGGAPAAWLRGIKAFLLALPVNCIGIGYAFLAMRKVVEALGIVSGSPVEVL
GGTPDTVVLLAVVAVMVLVYTVAGGLWAVVITDFVQLLLALLGAVAVAWAAVHAAGGMDAMLDQLRGLERPELLAIVPWQ
WNGDGFDWIGGAEISVATFLSYLTVQWWSFRRSDGGGEFIQRMLATRDERQAQLAGWVFLVVNYLVRSWLWVLVALAALV
LLPAQADWELSYPTLAVTYLPPVVLGLVVVSLVAAFMSTVSTAVNWGASYLTHDLYQRFIRPDADQRELLLVGQFTSVLL
LVLGVITALISDSIGTVFRLVIAIGTGPGVVLVLRWFWWRINAAAELAAMVCGFVVGLCTSVMPLVTIPDYGTRLMITTA
ITAVVWVVVMLVTPPESPQVLERFVNQVQPPGPGWSRLRQRLDITPVDSLGSLCLRFILSVGVLFGGLLGTGAFLLHQQL
GGWIGLVVTVICVLPLTRGWLRSRIGVA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507033, Length=427, Percent_Identity=25.7611241217799, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI109659836, Length=559, Percent_Identity=25.4025044722719, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4507031, Length=557, Percent_Identity=23.3393177737882, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI14140236, Length=513, Percent_Identity=24.1715399610136, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI109659839, Length=575, Percent_Identity=24.8695652173913, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI17941285, Length=481, Percent_Identity=24.5322245322245, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI110835708, Length=552, Percent_Identity=23.5507246376812, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI206597483, Length=547, Percent_Identity=23.0347349177331, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790113, Length=509, Percent_Identity=23.9685658153242, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790503, Length=475, Percent_Identity=21.6842105263158, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 63759; Mature: 63628

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIDWMILVGYLAITLVIGLWLSRRNRSEDDYFVAGRRLSGWLAGASMAATTFSIDTPL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCHHHHHEEECCCCH
YVAGLVGTRGLAGNWEWWSFGLAHVAMAVVFAPLWRRSGVLTDAAFTELRYGGAPAAWLR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
GIKAFLLALPVNCIGIGYAFLAMRKVVEALGIVSGSPVEVLGGTPDTVVLLAVVAVMVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
YTVAGGLWAVVITDFVQLLLALLGAVAVAWAAVHAAGGMDAMLDQLRGLERPELLAIVPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEE
QWNGDGFDWIGGAEISVATFLSYLTVQWWSFRRSDGGGEFIQRMLATRDERQAQLAGWVF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHH
LVVNYLVRSWLWVLVALAALVLLPAQADWELSYPTLAVTYLPPVVLGLVVVSLVAAFMST
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
VSTAVNWGASYLTHDLYQRFIRPDADQRELLLVGQFTSVLLLVLGVITALISDSIGTVFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIAIGTGPGVVLVLRWFWWRINAAAELAAMVCGFVVGLCTSVMPLVTIPDYGTRLMITT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH
AITAVVWVVVMLVTPPESPQVLERFVNQVQPPGPGWSRLRQRLDITPVDSLGSLCLRFIL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
SVGVLFGGLLGTGAFLLHQQLGGWIGLVVTVICVLPLTRGWLRSRIGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAIDWMILVGYLAITLVIGLWLSRRNRSEDDYFVAGRRLSGWLAGASMAATTFSIDTPL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCHHHHHEEECCCCH
YVAGLVGTRGLAGNWEWWSFGLAHVAMAVVFAPLWRRSGVLTDAAFTELRYGGAPAAWLR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
GIKAFLLALPVNCIGIGYAFLAMRKVVEALGIVSGSPVEVLGGTPDTVVLLAVVAVMVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
YTVAGGLWAVVITDFVQLLLALLGAVAVAWAAVHAAGGMDAMLDQLRGLERPELLAIVPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEE
QWNGDGFDWIGGAEISVATFLSYLTVQWWSFRRSDGGGEFIQRMLATRDERQAQLAGWVF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHH
LVVNYLVRSWLWVLVALAALVLLPAQADWELSYPTLAVTYLPPVVLGLVVVSLVAAFMST
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
VSTAVNWGASYLTHDLYQRFIRPDADQRELLLVGQFTSVLLLVLGVITALISDSIGTVFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIAIGTGPGVVLVLRWFWWRINAAAELAAMVCGFVVGLCTSVMPLVTIPDYGTRLMITT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH
AITAVVWVVVMLVTPPESPQVLERFVNQVQPPGPGWSRLRQRLDITPVDSLGSLCLRFIL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
SVGVLFGGLLGTGAFLLHQQLGGWIGLVVTVICVLPLTRGWLRSRIGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]