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The map label for this gene is lpxA [H]

Identifier: 33863677

GI number: 33863677

Start: 1496576

End: 1497427

Strand: Reverse

Name: lpxA [H]

Synonym: PMT1410

Alternate gene names: 33863677

Gene position: 1497427-1496576 (Counterclockwise)

Preceding gene: 33863678

Following gene: 33863676

Centisome position: 62.11

GC content: 54.93

Gene sequence:

>852_bases
ATGAGCGAGGTGAGCAAACTCTCAGCGATCACTGCAGAAAAAAAGGCTCAGGTTCACCCTGCGGCTGTGGTGGATCCTCG
TGCTGAGCTCGCTTCCGGTGTCATTGTTGGGCCGGGAGCAGTGATTGGACCTGATGTCAAGATTGGTCCTGATACTTGGA
TTGGCCCCCATGTGGTGCTCGATGGCCGTTTGACCCTTGGCGCCAATAACCGGGTTTTCCCCGGAGCCTGCCTTGGTCTT
GAGCCACAGGACCTCAAGTATCGCGGCGCACCTACAGAGGTGGTGATTGGCGATGCCAACACAATTAGGGAATACGTCAC
CATCAACCGTGCCACGGAGGAAGGTGAACAGACCAAGATCGGTAATCACAACTTGTTGATGGCCTATTGCCACCTTGGTC
ACAACTGTGTGCTGGGCAATGGGATTGTGATGTCGAATGGAATTCAAATGGCTGGTCATGTCTTGGTCGAAGACCGGGCC
GTGATCGGTGGCTGCTTAGGAATTCACCAATTCGTTCACATTGGCAGTCTTGCCATGGTGGGAGGCATGACAAGGGTTGA
TCGCGATGTCCCCCCGTACTGCCTCGCCGAAGGGCATCCAGGTCGATTGAGGGGTCTCAATCGCGTTGGCCTGCGGCGCA
GTGGTCTGAAGACTCAAGAGGGAGGAGAACTTGTCCAGTTGCAAGAGATTTGGAATTTGCTGTTTCGATCTGACCATGTC
TTTGTTGAGGGGTTGCGGCTTGCTCGACAAGAGCAGTTGATGCCAGCGGGTGCACACCTCTGTGCCTTTCTGGAGGCCTC
GATTGAGAAGGGACGTCGTGGTCCTATGCCTGCGATGTCTTTGAGTCGCTGA

Upstream 100 bases:

>100_bases
TGAAGCGGCAGCGCTTTGGCAAGGTCAGGGGTGAAGCCAGGGTGGAGGGCCAGCTGGTTTGCTCTGGTGAGTTGATGTTT
TCCTTGGTGGACTGAGGATC

Downstream 100 bases:

>100_bases
TGGTGCGCCTGCTGATCAGCACTGGCGAGGTCTCTGGTGATTTGCAGGGAAGTCTCTTGATTCAAGCTCTCCAAAGGGAG
GTTGAACGGCGTTCCTTACC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSEVSKLSAITAEKKAQVHPAAVVDPRAELASGVIVGPGAVIGPDVKIGPDTWIGPHVVLDGRLTLGANNRVFPGACLGL
EPQDLKYRGAPTEVVIGDANTIREYVTINRATEEGEQTKIGNHNLLMAYCHLGHNCVLGNGIVMSNGIQMAGHVLVEDRA
VIGGCLGIHQFVHIGSLAMVGGMTRVDRDVPPYCLAEGHPGRLRGLNRVGLRRSGLKTQEGGELVQLQEIWNLLFRSDHV
FVEGLRLARQEQLMPAGAHLCAFLEASIEKGRRGPMPAMSLSR

Sequences:

>Translated_283_residues
MSEVSKLSAITAEKKAQVHPAAVVDPRAELASGVIVGPGAVIGPDVKIGPDTWIGPHVVLDGRLTLGANNRVFPGACLGL
EPQDLKYRGAPTEVVIGDANTIREYVTINRATEEGEQTKIGNHNLLMAYCHLGHNCVLGNGIVMSNGIQMAGHVLVEDRA
VIGGCLGIHQFVHIGSLAMVGGMTRVDRDVPPYCLAEGHPGRLRGLNRVGLRRSGLKTQEGGELVQLQEIWNLLFRSDHV
FVEGLRLARQEQLMPAGAHLCAFLEASIEKGRRGPMPAMSLSR
>Mature_282_residues
SEVSKLSAITAEKKAQVHPAAVVDPRAELASGVIVGPGAVIGPDVKIGPDTWIGPHVVLDGRLTLGANNRVFPGACLGLE
PQDLKYRGAPTEVVIGDANTIREYVTINRATEEGEQTKIGNHNLLMAYCHLGHNCVLGNGIVMSNGIQMAGHVLVEDRAV
IGGCLGIHQFVHIGSLAMVGGMTRVDRDVPPYCLAEGHPGRLRGLNRVGLRRSGLKTQEGGELVQLQEIWNLLFRSDHVF
VEGLRLARQEQLMPAGAHLCAFLEASIEKGRRGPMPAMSLSR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=226, Percent_Identity=42.0353982300885, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 30316; Mature: 30184

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVSKLSAITAEKKAQVHPAAVVDPRAELASGVIVGPGAVIGPDVKIGPDTWIGPHVVL
CCHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCEEECCCCEECCCCEECCCCCCCCEEEE
DGRLTLGANNRVFPGACLGLEPQDLKYRGAPTEVVIGDANTIREYVTINRATEEGEQTKI
CCEEEECCCCCCCCCEEECCCCCCCEECCCCCEEEECCHHHHHHHHEEECCCCCCCCCCC
GNHNLLMAYCHLGHNCVLGNGIVMSNGIQMAGHVLVEDRAVIGGCLGIHQFVHIGSLAMV
CCCCEEEEEECCCCCEEEECCEEEECCCEEECEEEEECCHHHHHHHHHHHHHHHHHHHHH
GGMTRVDRDVPPYCLAEGHPGRLRGLNRVGLRRSGLKTQEGGELVQLQEIWNLLFRSDHV
CCCHHHCCCCCCCEECCCCCHHHCCCHHHCCHHCCCCCCCCCCEEEHHHHHHHHHCCCCH
FVEGLRLARQEQLMPAGAHLCAFLEASIEKGRRGPMPAMSLSR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEVSKLSAITAEKKAQVHPAAVVDPRAELASGVIVGPGAVIGPDVKIGPDTWIGPHVVL
CHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCEEECCCCEECCCCEECCCCCCCCEEEE
DGRLTLGANNRVFPGACLGLEPQDLKYRGAPTEVVIGDANTIREYVTINRATEEGEQTKI
CCEEEECCCCCCCCCEEECCCCCCCEECCCCCEEEECCHHHHHHHHEEECCCCCCCCCCC
GNHNLLMAYCHLGHNCVLGNGIVMSNGIQMAGHVLVEDRAVIGGCLGIHQFVHIGSLAMV
CCCCEEEEEECCCCCEEEECCEEEECCCEEECEEEEECCHHHHHHHHHHHHHHHHHHHHH
GGMTRVDRDVPPYCLAEGHPGRLRGLNRVGLRRSGLKTQEGGELVQLQEIWNLLFRSDHV
CCCHHHCCCCCCCEECCCCCHHHCCCHHHCCHHCCCCCCCCCCEEEHHHHHHHHHCCCCH
FVEGLRLARQEQLMPAGAHLCAFLEASIEKGRRGPMPAMSLSR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA