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The map label for this gene is degU [H]

Identifier: 33863672

GI number: 33863672

Start: 1491175

End: 1491873

Strand: Direct

Name: degU [H]

Synonym: PMT1405

Alternate gene names: 33863672

Gene position: 1491175-1491873 (Clockwise)

Preceding gene: 33863668

Following gene: 33863673

Centisome position: 61.85

GC content: 54.08

Gene sequence:

>699_bases
CTGCAGAAAACAAGTCAACAAATCCATCCCCTGCTCCGTCGCAGTCGCACTGTTGTCGCCACAGCCGATCGCGTCTTAAT
CACAAGTTGGGTGGGCTGGTTTGATTGTCTGGGTCCCCTAGTGGGCGCTGCAACCGGTGAGGACGAGACCCTCAGTTGCC
TGAAAAGCTCGAATGCAGATCTCCTGATCTGCACCGATCTACTGGAGAGCGGGAATGGCCCAAGCCTGGTCCGTAAAGCA
AAACAGCTCAAGCCTGATCTCAAGGCCCTGATGCTGATTCAACGACCTTTATTACGCACCCTGCTGGATGCAATAGAAGC
CCATTGCGATGGCCTCTGCGCCCATGAGCTCGTCGGCAGTGGCACCCTGCTGGCAGCTCTAAGCGCAATCGAAAGCGATG
GAACCTACTTAGACAGTGTGGTTGCAGGAGTTTTACGTCACGGTCGTCTCGGAAATGGCAAGAGCAGCCGCCAAATCGAC
AACCTCAGCTTGCGCGAGGGAGATGTACTTCGAGGAATCTGTAAAGGGATGAGCAATCAGAACATTGCCGATGAGCTCTA
TCTCTCGATCGATACGGTCAAGAGCCATGTGCACAACCTGCTGCAAAAATTGCCAGCACGAGATCGCACCCATGCCGTAG
TGGTGGCTTTTCGTGATGGGCTGGTGGAGTTACCTCAAAGACTGCCACGTTGGCAATAA

Upstream 100 bases:

>100_bases
CGTCAGAAACAGTGCGGATCAACGTAATCTCCATGATGAGGCTCTAACCGCTCCTGTTACCTGGTTGCAACCAGTGGACA
TCACTCCCCGGATCTCTTCT

Downstream 100 bases:

>100_bases
CGCTGCCTTAACTGACTCGGTAACGTCCGCCTCAATGAGCGATCCCCAAAGGGTGATTGGCATCTTTCACTTTGAGCCAA
CAAGCGCAGCTCCAAAGCTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MQKTSQQIHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNADLLICTDLLESGNGPSLVRKA
KQLKPDLKALMLIQRPLLRTLLDAIEAHCDGLCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLGNGKSSRQID
NLSLREGDVLRGICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRWQ

Sequences:

>Translated_232_residues
MQKTSQQIHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNADLLICTDLLESGNGPSLVRKA
KQLKPDLKALMLIQRPLLRTLLDAIEAHCDGLCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLGNGKSSRQID
NLSLREGDVLRGICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRWQ
>Mature_232_residues
MQKTSQQIHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNADLLICTDLLESGNGPSLVRKA
KQLKPDLKALMLIQRPLLRTLLDAIEAHCDGLCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLGNGKSSRQID
NLSLREGDVLRGICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRWQ

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25285; Mature: 25285

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTSQQIHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNAD
CCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
LLICTDLLESGNGPSLVRKAKQLKPDLKALMLIQRPLLRTLLDAIEAHCDGLCAHELVGS
EEEEHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GTLLAALSAIESDGTYLDSVVAGVLRHGRLGNGKSSRQIDNLSLREGDVLRGICKGMSNQ
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
NIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRWQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCHHHHHHHCCCCC
>Mature Secondary Structure
MQKTSQQIHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNAD
CCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
LLICTDLLESGNGPSLVRKAKQLKPDLKALMLIQRPLLRTLLDAIEAHCDGLCAHELVGS
EEEEHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GTLLAALSAIESDGTYLDSVVAGVLRHGRLGNGKSSRQIDNLSLREGDVLRGICKGMSNQ
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
NIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRWQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]