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The map label for this gene is cysQ [H]

Identifier: 33863645

GI number: 33863645

Start: 1463341

End: 1464258

Strand: Reverse

Name: cysQ [H]

Synonym: PMT1378

Alternate gene names: 33863645

Gene position: 1464258-1463341 (Counterclockwise)

Preceding gene: 33863648

Following gene: 33863631

Centisome position: 60.74

GC content: 55.99

Gene sequence:

>918_bases
ATGATGCCGAACGCACCTGTTCTGCCTGATGGTGTGAACCTGGAGATTTTGTTGCAGCACTTGAGGCGATTGAGCTGGGG
TGCTGCAGACATCCTGCTGGCCTATGCCCGGGGAGAACAGCCACCGCATGGATTTTCTAAGGCTCTGAGTGTTGAGGATG
GTGGTGAGGGGCCTGTTTCTGCCGCTGACCTTGCGGTGAATCGCTGGCTTCTGGATGGCTTAGAAGCGAATTTCCCCTTG
GCAGATTGGACTCTATTGAGTGAGGAGACAGCAAAGGAGCAACTCACTGCAGGCGAACCCTTAGCGGCGGAATGGTTGTG
GATCCTTGATCCCTTGGATGGCACAAAGGATTTCTTGCAGGGCACAGGTGAATACGCCGTGCATCTCGCTTTGGTGCGTG
GTCAACGCCCAGTGCTTGGAGTGGTACTCCTGCCAGAAGCCGAGGAGCTTTGGTTCGGTGTGATCGGTTCTGGGGCTTGG
TGCGAAGACCGGCGGGGAAAACGTTCGCCGGTGCGTTTTAGTCAGCGCCAGGCTGTTTGTGAGTTGATGCTGGTAGCGAG
TCGCAACCACCGCGACAACAGGCTTGAACAGCTGCTAGAGAGTCTTGCTCTTGGTGGTAGCAAGGCTGTGGGCAGTGTGG
GTTGCAAGGTGACCACGATTTTGCGCGGAGAAACAGATTTGTATGTCTCTCTTTCAGGCCGTAGTGCTCCAAAAGATTGG
GATATGGCGGCTCCAGAGGCGGTGCTGATGGCGGCAGGGGGATGTTTCACTCATGCTGATGGACGCCAGCTTGCTTATAA
CAGCGGTGATGTACGTCAGGCTGGATGTTTAATCGCCAGCCATGGGCTCGCCCACGCCCAGCTTTGTGAAGCAGCGGCGC
GGGCTATGAAAGAGATCGACCCAGGCTTTCAGGTTTGA

Upstream 100 bases:

>100_bases
AGAGATCTCCGAGGTGACCAATGGGCGTGCCAACCACATAGAGCACCCCTGGTGCTGGTTCCTCTCGTTGACTCACAATG
TGGCCTGCACGTGTCTATGC

Downstream 100 bases:

>100_bases
ATTGACCTGAAGCAGCCGATTAGTTGAGAGGGGCTACAGGAGTTGGAGCTGGCTCTGATTGAGTCTCTTCGCCGTTTTGA
GGCACGCCTCTGAGTGTGAG

Product: 3'-phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MMPNAPVLPDGVNLEILLQHLRRLSWGAADILLAYARGEQPPHGFSKALSVEDGGEGPVSAADLAVNRWLLDGLEANFPL
ADWTLLSEETAKEQLTAGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLALVRGQRPVLGVVLLPEAEELWFGVIGSGAW
CEDRRGKRSPVRFSQRQAVCELMLVASRNHRDNRLEQLLESLALGGSKAVGSVGCKVTTILRGETDLYVSLSGRSAPKDW
DMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEAAARAMKEIDPGFQV

Sequences:

>Translated_305_residues
MMPNAPVLPDGVNLEILLQHLRRLSWGAADILLAYARGEQPPHGFSKALSVEDGGEGPVSAADLAVNRWLLDGLEANFPL
ADWTLLSEETAKEQLTAGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLALVRGQRPVLGVVLLPEAEELWFGVIGSGAW
CEDRRGKRSPVRFSQRQAVCELMLVASRNHRDNRLEQLLESLALGGSKAVGSVGCKVTTILRGETDLYVSLSGRSAPKDW
DMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEAAARAMKEIDPGFQV
>Mature_305_residues
MMPNAPVLPDGVNLEILLQHLRRLSWGAADILLAYARGEQPPHGFSKALSVEDGGEGPVSAADLAVNRWLLDGLEANFPL
ADWTLLSEETAKEQLTAGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLALVRGQRPVLGVVLLPEAEELWFGVIGSGAW
CEDRRGKRSPVRFSQRQAVCELMLVASRNHRDNRLEQLLESLALGGSKAVGSVGCKVTTILRGETDLYVSLSGRSAPKDW
DMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEAAARAMKEIDPGFQV

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=214, Percent_Identity=31.7757009345794, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193202572, Length=231, Percent_Identity=25.974025974026, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71995897, Length=250, Percent_Identity=28, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995905, Length=250, Percent_Identity=28, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193202570, Length=233, Percent_Identity=25.7510729613734, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24651149, Length=267, Percent_Identity=29.2134831460674, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24664922, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664926, Length=224, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 32811; Mature: 32811

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPNAPVLPDGVNLEILLQHLRRLSWGAADILLAYARGEQPPHGFSKALSVEDGGEGPVS
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCH
AADLAVNRWLLDGLEANFPLADWTLLSEETAKEQLTAGEPLAAEWLWILDPLDGTKDFLQ
HHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
GTGEYAVHLALVRGQRPVLGVVLLPEAEELWFGVIGSGAWCEDRRGKRSPVRFSQRQAVC
CCCCCEEEEEEECCCCCEEEEEECCCHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
ELMLVASRNHRDNRLEQLLESLALGGSKAVGSVGCKVTTILRGETDLYVSLSGRSAPKDW
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCC
DMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEAAARAMKEID
CCCCCCEEEEECCCCEECCCCCEEEECCCCCHHHCEEEHHCCCHHHHHHHHHHHHHHHCC
PGFQV
CCCCC
>Mature Secondary Structure
MMPNAPVLPDGVNLEILLQHLRRLSWGAADILLAYARGEQPPHGFSKALSVEDGGEGPVS
CCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCH
AADLAVNRWLLDGLEANFPLADWTLLSEETAKEQLTAGEPLAAEWLWILDPLDGTKDFLQ
HHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
GTGEYAVHLALVRGQRPVLGVVLLPEAEELWFGVIGSGAWCEDRRGKRSPVRFSQRQAVC
CCCCCEEEEEEECCCCCEEEEEECCCHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
ELMLVASRNHRDNRLEQLLESLALGGSKAVGSVGCKVTTILRGETDLYVSLSGRSAPKDW
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCC
DMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEAAARAMKEID
CCCCCCEEEEECCCCEECCCCCEEEECCCCCHHHCEEEHHCCCHHHHHHHHHHHHHHHCC
PGFQV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]