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The map label for this gene is trpF [H]

Identifier: 33863494

GI number: 33863494

Start: 1312988

End: 1313665

Strand: Direct

Name: trpF [H]

Synonym: PMT1226

Alternate gene names: 33863494

Gene position: 1312988-1313665 (Clockwise)

Preceding gene: 33863492

Following gene: 33863501

Centisome position: 54.46

GC content: 54.87

Gene sequence:

>678_bases
ATGGTCTTGCCTATGGGATCTCCAACATCCACCGCAGTGAAGATCTGCGGTCTTACCAACATTGACCAAGCCAAATCGAT
TGCAGCGCTAGGTGTCGAAGCAATTGGCGTAATCGGCGTAGCAAGCTCACCCCGCTTTGTTGCAGAACAGCAACGACGAG
ACCTTTTCGCTCAACTCAACAGCTTCAAGCCAGAACTCCAACGAGTCTGGGTGGTCGCTGATCCAGATGACACCGACCTA
TCCGAAGCCCTGCAAGGAGAAGGTGCACCTTCGGCAATCCAGCTTCACGGCCAAGAAACGCCAGAACACTGCGCAAACCT
GCGCATCCAACACCCGAACACGCAGTGGTGGAAAGCCCTGCGCATCCGTAGCCATGAGGATCTCTCCCTTGCCCATACCT
ATGCAGGCCAGGTCGACGCACTCCTTCTCGATGCATGGAGGCCTGGACAACTTGGTGGCACAGGCCATCGACTTCCCCTG
AACTGGCTGCATCAAACCTCTTTTGAACTGCCCTGGTGGTTAGCGGGTGGTGTCTCCGCAGAGTGGATTCCAGAACTTTT
GAGCCAGGTAAATCCATGGGGCTTGGACGCCTCAAGCCGTCTCGAGATTTCGCCAGGGATTAAGGATCTAAAACTGGTTG
AGGCCCTGGTTGAAGCGGTACGTCAGCAGCAAAAATAG

Upstream 100 bases:

>100_bases
CCCGAATCTTCATCAGCTCCCAGCCTTCGCCCACCCTTTCATCTCCATCGAGCCGGATCAGCGGCCAGTAGCAAACCAAT
CTTAGAAAAGTCTCGAGCCA

Downstream 100 bases:

>100_bases
ATTCAATGATGCAATCAAAGCTCTTAAACAATTTGAGCTGCCGCAGATTTTTTCAATGGGTTGAAATTGAATTTCAATAA
TAAAGAGCGAACAAACAATA

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRFVAEQQRRDLFAQLNSFKPELQRVWVVADPDDTDL
SEALQGEGAPSAIQLHGQETPEHCANLRIQHPNTQWWKALRIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPL
NWLHQTSFELPWWLAGGVSAEWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVEAVRQQQK

Sequences:

>Translated_225_residues
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRFVAEQQRRDLFAQLNSFKPELQRVWVVADPDDTDL
SEALQGEGAPSAIQLHGQETPEHCANLRIQHPNTQWWKALRIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPL
NWLHQTSFELPWWLAGGVSAEWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVEAVRQQQK
>Mature_225_residues
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRFVAEQQRRDLFAQLNSFKPELQRVWVVADPDDTDL
SEALQGEGAPSAIQLHGQETPEHCANLRIQHPNTQWWKALRIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPL
NWLHQTSFELPWWLAGGVSAEWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVEAVRQQQK

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=209, Percent_Identity=33.0143540669856, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24707; Mature: 24707

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRFVAEQQRRDLFAQLN
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHH
SFKPELQRVWVVADPDDTDLSEALQGEGAPSAIQLHGQETPEHCANLRIQHPNTQWWKAL
CCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHCCEECCCCHHHHHHH
RIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPLNWLHQTSFELPWWLAGGVSA
HHCCCCCCHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCH
EWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVEAVRQQQK
HHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVLPMGSPTSTAVKICGLTNIDQAKSIAALGVEAIGVIGVASSPRFVAEQQRRDLFAQLN
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHH
SFKPELQRVWVVADPDDTDLSEALQGEGAPSAIQLHGQETPEHCANLRIQHPNTQWWKAL
CCCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHCCEECCCCHHHHHHH
RIRSHEDLSLAHTYAGQVDALLLDAWRPGQLGGTGHRLPLNWLHQTSFELPWWLAGGVSA
HHCCCCCCHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCH
EWIPELLSQVNPWGLDASSRLEISPGIKDLKLVEALVEAVRQQQK
HHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA