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The map label for this gene is ruvC [H]

Identifier: 33863407

GI number: 33863407

Start: 1227761

End: 1228225

Strand: Direct

Name: ruvC [H]

Synonym: PMT1136

Alternate gene names: 33863407

Gene position: 1227761-1228225 (Clockwise)

Preceding gene: 33863406

Following gene: 33863408

Centisome position: 50.93

GC content: 58.28

Gene sequence:

>465_bases
TTGCGCATCCTTGGCATCGACCCTGGCATTGCCAGGGTGGGCTACGGGGTCATCGACACCAGCAACGGACAACAGCAGAT
GCTCGATTGCGGCATCATCCGCACCAATCCCGGCATTGACGATGGTGAACGGATGGTGGAAATCGCCAGCGATCTACGCC
AGCTCATCCGTCGTTGGAAGCCCCAACTGGCCGCTGTGGAGAAATTCTTCTTCTACCGCTCCAGCACGACAATCAGCGTG
GTCCAGGCACGTGGAGTCATCATCATGACCCTGGCACGCTTTCGAGTGCCAGTGATGGAATTCCCACCGATGCAGATCAA
GCTTGCTCTGGCGGGCTCAGGCCATGCTGAAAAAGATGAAGTGCTCGATGCGGTGATGCGCGAATTGAATCTTGATCAGC
CGCCCCGACCCGATGATGCCGCCGACGCCCTGGCCATAGCACTCACGGGTTGGTTCCAGCGCTAA

Upstream 100 bases:

>100_bases
TCAGGGGATCGGGTCGTCAAAATTTTCTGCAAAGTATTCGAACGCAGCGAGAACAGCGATCAGGCTGACTTCGAGCTAAC
AACTCAAGCAGGCTGAACGC

Downstream 100 bases:

>100_bases
AACCACTGATGGACTCCTCCTGCTCACCAAAACACGGCTGGTTTGACAGCGTGGCTGAGTCCTACGCCCAACAGCGCCCC
TATTACCCGGAATCCCTGTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRILGIDPGIARVGYGVIDTSNGQQQMLDCGIIRTNPGIDDGERMVEIASDLRQLIRRWKPQLAAVEKFFFYRSSTTISV
VQARGVIIMTLARFRVPVMEFPPMQIKLALAGSGHAEKDEVLDAVMRELNLDQPPRPDDAADALAIALTGWFQR

Sequences:

>Translated_154_residues
MRILGIDPGIARVGYGVIDTSNGQQQMLDCGIIRTNPGIDDGERMVEIASDLRQLIRRWKPQLAAVEKFFFYRSSTTISV
VQARGVIIMTLARFRVPVMEFPPMQIKLALAGSGHAEKDEVLDAVMRELNLDQPPRPDDAADALAIALTGWFQR
>Mature_154_residues
MRILGIDPGIARVGYGVIDTSNGQQQMLDCGIIRTNPGIDDGERMVEIASDLRQLIRRWKPQLAAVEKFFFYRSSTTISV
VQARGVIIMTLARFRVPVMEFPPMQIKLALAGSGHAEKDEVLDAVMRELNLDQPPRPDDAADALAIALTGWFQR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=136, Percent_Identity=35.2941176470588, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 17138; Mature: 17138

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIDPGIARVGYGVIDTSNGQQQMLDCGIIRTNPGIDDGERMVEIASDLRQLIRRWK
CEEECCCCCHHHHCCCEEECCCCHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHC
PQLAAVEKFFFYRSSTTISVVQARGVIIMTLARFRVPVMEFPPMQIKLALAGSGHAEKDE
HHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHCCCCCCCCCCEEEEEECCCCCCCHHH
VLDAVMRELNLDQPPRPDDAADALAIALTGWFQR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRILGIDPGIARVGYGVIDTSNGQQQMLDCGIIRTNPGIDDGERMVEIASDLRQLIRRWK
CEEECCCCCHHHHCCCEEECCCCHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHC
PQLAAVEKFFFYRSSTTISVVQARGVIIMTLARFRVPVMEFPPMQIKLALAGSGHAEKDE
HHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHCCCCCCCCCCEEEEEECCCCCCCHHH
VLDAVMRELNLDQPPRPDDAADALAIALTGWFQR
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA