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The map label for this gene is dapB

Identifier: 33863086

GI number: 33863086

Start: 888603

End: 889454

Strand: Reverse

Name: dapB

Synonym: PMT0814

Alternate gene names: 33863086

Gene position: 889454-888603 (Counterclockwise)

Preceding gene: 33863088

Following gene: 33863085

Centisome position: 36.89

GC content: 51.88

Gene sequence:

>852_bases
ATGACCTCAGTCCCTCCAGAGTTGATTCCTGTTGTGGTTGTTGGCGCACTGGGCCGCATGGGGGCTGAGGTCATCAAAGC
TGTTCATCTCGCTTCGGATTGTGAGTTGGTTGGTGCAGTCGACACAACGCCAGGCAAGGAAGGTGTGGAGATAGGCGAGG
AGCTTGGAATTGGTGTTCTTGATGTTGCTTTGACGTCCGACATTGAGGCTTGTCTTTGTTCTGTCAGCCAGTCTTTTCAT
AGGACTGGCCCTGGACAAGGCGCTGTGCTTGTTGATTTCACACATCCTTCAGTGGTTTATGAGCACACCAGGGCGGCGTT
TGCCTATGGGGTTCATCCGGTCATAGGCACCACAGGACTCTCACATCAGCAGTTGGTTGATCTCAGTGAATTTGCAGCAA
AAGCGTCGATGGGAGGCGCTGTGATTCCAAATTTCTCTGTTGGCATGGTCTTACTGCAACAGGCAGCAGCTGCGGCTGCA
CGCTTTTATGACAATGCAGAACTCACTGAGCTGCATCACAACCGTAAGGCTGATGCCCCGAGTGGCACATGTATAAAAAC
TGCAGAGATGATGGAGGAGCTCGGTAAAAGTTTTAATTCGCCTGAAGTTGATGAGCATGAATCGCTGACTGGTTCCCGTG
GTGGCTTACGAGCTAGTGGCTTAAGACTCCATTCGCTTCGTCTGCCTGGATTGGTTGCCCATCAGGAAGTGATGTTCGGA
GCTCCTGGAGAGAGCTATACACTCCGGCACGACACCATTGATCGTTCGGCCTACATGCCAGGTGTGTTGCTAACCGTTCG
TAAGGTGCGACAGCTTCAAGGTCTGGTTTATGGCCTTGAACGCCTCATCTGA

Upstream 100 bases:

>100_bases
TAATTCGATGAAGCCTAGGTTGTCTGGGGCTCAGAGTGAAGTTCGCTGCCTGGGTGTTACATGAGTCGACCCATAGGCTT
TATTCAGCGATCGCCCTCCC

Downstream 100 bases:

>100_bases
AATTCATTTGCGTGTCGATGTTGGTCCCTTTGCGTCCAGGAGAGCTTCAGAGGCTTATCCCTGCAGTGGCCACCAGTAAT
CAATTCGCAGCGGCCCTTGG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTSVPPELIPVVVVGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEIGEELGIGVLDVALTSDIEACLCSVSQSFH
RTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGLSHQQLVDLSEFAAKASMGGAVIPNFSVGMVLLQQAAAAAA
RFYDNAELTELHHNRKADAPSGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI

Sequences:

>Translated_283_residues
MTSVPPELIPVVVVGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEIGEELGIGVLDVALTSDIEACLCSVSQSFH
RTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGLSHQQLVDLSEFAAKASMGGAVIPNFSVGMVLLQQAAAAAA
RFYDNAELTELHHNRKADAPSGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI
>Mature_282_residues
TSVPPELIPVVVVGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEIGEELGIGVLDVALTSDIEACLCSVSQSFHR
TGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGLSHQQLVDLSEFAAKASMGGAVIPNFSVGMVLLQQAAAAAAR
FYDNAELTELHHNRKADAPSGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFGA
PGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=277, Percent_Identity=30.3249097472924, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_PROMM (Q7V7D4)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_894646.1
- ProteinModelPortal:   Q7V7D4
- SMR:   Q7V7D4
- STRING:   Q7V7D4
- GeneID:   1729228
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT0814
- NMPDR:   fig|74547.1.peg.813
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   YNNENIE
- ProtClustDB:   PRK00048
- BioCyc:   PMAR74547:PMT0814-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29962; Mature: 29830

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVPPELIPVVVVGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEIGEELGIGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHCCCHH
DVALTSDIEACLCSVSQSFHRTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCC
SHQQLVDLSEFAAKASMGGAVIPNFSVGMVLLQQAAAAAARFYDNAELTELHHNRKADAP
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
SGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
CCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCEECCEEEEEECCCCHHHHHHHEEC
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI
CCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TSVPPELIPVVVVGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEIGEELGIGVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHCCCHH
DVALTSDIEACLCSVSQSFHRTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCC
SHQQLVDLSEFAAKASMGGAVIPNFSVGMVLLQQAAAAAARFYDNAELTELHHNRKADAP
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
SGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
CCCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCEECCEEEEEECCCCHHHHHHHEEC
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI
CCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642