Click here to switch to the map view.

The map label for this gene is htpG [H]

Identifier: 33862968

GI number: 33862968

Start: 750641

End: 752551

Strand: Reverse

Name: htpG [H]

Synonym: PMT0696

Alternate gene names: 33862968

Gene position: 752551-750641 (Counterclockwise)

Preceding gene: 33862969

Following gene: 33862967

Centisome position: 31.21

GC content: 45.0

Gene sequence:

>1911_bases
ATGACTGTGCTGGAAGAAGGTCAAATCCAGATTCACACCGAGAATATTTTCCCGATCATCAAGAAAGCCGTTTATTCCGG
CCACGAGGTTTTCTTGAGAGAGCTAGTCAGCAATGGCGTCGATGCAATAAGCAAAAGACGCATGGCAGCCATAGCAGGTG
ACTGCACTGAAGCTGAAGAAGGAGTTATTGATATCAAGATTGACCGAGAAGCAAAGACACTCACTATCTCTGACAACGGA
ATCGGCATGACAACCGATGAGGTTAAGAAATACATTAATCAGGTTGCCTTCTCAAGTGCAGAAGACTTCCTTGAAAAATA
CAAGCAGGAAAGTGACGGAATCATTGGTCATTTTGGGCTAGGTTTTTATTCTTCATTCATGGTATCGAAGCATGTAGAGC
TAGTCACTAAGTCTGCTTGTTCCGAGAGTAAAGCTATTCGTTGGAGCTGTGATGGCTCACCAAGATTTAACATCCAAGAA
GCCGAACGCAATGAAGCAGGAACCGATGTCATCCTTCATCTTATGGATGAAGAGTTGGAATACATCGAGCCAAGTCGAAT
CCGTACTCTGATCACAAAATACTGTGACTTTATGCCTGTTGAGGTAAAACTCGAAGGCGAGTCAATCAATAAGCGAAATC
CTCTTTGGAGGCGCAACCCAAGAGAAATCACTGATCAGGAGTATATCGAACTCTATAATTATCTATATCCATTCCAAGGT
GATCCTCTTCTTTGGGTGCACCTAAATACTGATTACCCCTATAACCTTCAGGGTATTCTCTATTTCCCTCGAATTGGTGG
TCGCGCAGATTGGGAAAAAGGTGAGATAAAACTCTACTGCAATCAAGTATTTGTCAGTGATTCAATTAAAGAAGTAGTAC
CACACTACCTTCTTCCCCTAAGAGGTGTGATCGACTCACCTGACATTCCACTTAATGTCAGTCGTAGCGCATTACAAACA
GACAGACGTGTTAGATCTATTGGGAATTTTGTTGCAAAGAAAGTTGCCGATCGTCTGCGAGGATTAAAGGCTGAACAACC
TCTTTTCTATGCTGAAGCATGGGATGCGTTAGCACCATTCGTCAAAATAGGATCAATGGAAGATGAAAAGTTTGCTGATC
AAGTTGCCGATCTAATCCTATTTGGTACGACTGCTCTGGCTTCAAAAGAAACAGATGGGGGCACTCCAGATCCAATTCCT
TGTGGGGAAAAAGCCTTCACTACGCTGAGTGGATACAAAAGTCGTCTGAGTACAGAAGCCAACAATCGCATTCTTTACTG
CACGGATGAAGTTGCCCAAGCGAGTGCCCTCAGCTTATGGACTTCACAGGGGGCTGAAATTCTTAAAACCGAAACGTTTA
TAGACAGCCAATTCCTTCCATGGCTTGAAGCGCGTCATGACGATCTCCGATTCCAGCGCGTTGATGCCGAATTGGATGAC
ACTCTTAAAGAGGACAAACCTGAACTAACTGACCAGGAAGGAGAGACCAAGTCTGAAAGCCTTAGAACTCTAATGAAGCA
ATCACTTAATAACGACAAGGTCACCATACAAGTACAAGCACTTAAGGGAGATAACGCACCTCCCGCAATGATTTTGCTGC
CAGAACAGATGCGACGTATGAACGACATTGGAGCCCTCATGGATCAAAGGCTGCCAGGTCTTCCCGAGCATCATGTCCTT
CTTGTCAATCGTCGTCATCCACTTGTCGAAGGACTTTTGAAACTCAAATCTGGATCCGTGCTGGTCAGCACTTCAGGTGT
GTCTCCAACCGAATCCTTGGCACAAGGCTTAGCCCGTCACCTATACGACATGGCTCGCCTCGGTGTAGGAGGTTTGGAGC
CCAATGAACTTGCTGGATTCCAAAGCCGTAGTGCTGTGTTGATGGGACAGCTGATGGATCGAGCTTTTTAA

Upstream 100 bases:

>100_bases
AAGCAGCTGAATTAATCACTAGGTACGGTCACCCCACCTAAAACCAGCTTGAGAACTGAGGCAAAGACTACCTAAGGTCA
AATCCTAAACAGTGAAACCA

Downstream 100 bases:

>100_bases
AGGAAAGGTGGATTTGATAAAATATTAGTTTGGGTTAAGCGCCCTAGCTCTGTAGAGGATCAAGACATGTCCCGGGTGTG
TCAGCTCACTGGAACTCGCG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MTVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAIAGDCTEAEEGVIDIKIDREAKTLTISDNG
IGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGLGFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQE
AERNEAGTDVILHLMDEELEYIEPSRIRTLITKYCDFMPVEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPLRGVIDSPDIPLNVSRSALQT
DRRVRSIGNFVAKKVADRLRGLKAEQPLFYAEAWDALAPFVKIGSMEDEKFADQVADLILFGTTALASKETDGGTPDPIP
CGEKAFTTLSGYKSRLSTEANNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHDDLRFQRVDAELDD
TLKEDKPELTDQEGETKSESLRTLMKQSLNNDKVTIQVQALKGDNAPPAMILLPEQMRRMNDIGALMDQRLPGLPEHHVL
LVNRRHPLVEGLLKLKSGSVLVSTSGVSPTESLAQGLARHLYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF

Sequences:

>Translated_636_residues
MTVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAIAGDCTEAEEGVIDIKIDREAKTLTISDNG
IGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGLGFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQE
AERNEAGTDVILHLMDEELEYIEPSRIRTLITKYCDFMPVEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPLRGVIDSPDIPLNVSRSALQT
DRRVRSIGNFVAKKVADRLRGLKAEQPLFYAEAWDALAPFVKIGSMEDEKFADQVADLILFGTTALASKETDGGTPDPIP
CGEKAFTTLSGYKSRLSTEANNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHDDLRFQRVDAELDD
TLKEDKPELTDQEGETKSESLRTLMKQSLNNDKVTIQVQALKGDNAPPAMILLPEQMRRMNDIGALMDQRLPGLPEHHVL
LVNRRHPLVEGLLKLKSGSVLVSTSGVSPTESLAQGLARHLYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF
>Mature_635_residues
TVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAIAGDCTEAEEGVIDIKIDREAKTLTISDNGI
GMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGLGFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQEA
ERNEAGTDVILHLMDEELEYIEPSRIRTLITKYCDFMPVEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQGD
PLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPLRGVIDSPDIPLNVSRSALQTD
RRVRSIGNFVAKKVADRLRGLKAEQPLFYAEAWDALAPFVKIGSMEDEKFADQVADLILFGTTALASKETDGGTPDPIPC
GEKAFTTLSGYKSRLSTEANNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHDDLRFQRVDAELDDT
LKEDKPELTDQEGETKSESLRTLMKQSLNNDKVTIQVQALKGDNAPPAMILLPEQMRRMNDIGALMDQRLPGLPEHHVLL
VNRRHPLVEGLLKLKSGSVLVSTSGVSPTESLAQGLARHLYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=643, Percent_Identity=27.6827371695179, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI4507677, Length=652, Percent_Identity=24.5398773006135, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI20149594, Length=456, Percent_Identity=27.6315789473684, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI153792590, Length=209, Percent_Identity=33.0143540669856, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI154146191, Length=209, Percent_Identity=33.0143540669856, Blast_Score=112, Evalue=1e-24,
Organism=Escherichia coli, GI1786679, Length=642, Percent_Identity=30.2180685358255, Blast_Score=245, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI115535205, Length=642, Percent_Identity=27.4143302180685, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI115535167, Length=398, Percent_Identity=31.1557788944724, Blast_Score=225, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17542208, Length=713, Percent_Identity=25.3856942496494, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17559162, Length=505, Percent_Identity=27.7227722772277, Blast_Score=188, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6323840, Length=597, Percent_Identity=27.8056951423786, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6325016, Length=206, Percent_Identity=33.9805825242718, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24586016, Length=665, Percent_Identity=26.4661654135338, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI21357739, Length=650, Percent_Identity=27.6923076923077, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17647529, Length=452, Percent_Identity=26.9911504424779, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71463; Mature: 71332

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAIAGDCTEAEE
CCCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC
GVIDIKIDREAKTLTISDNGIGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGL
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEHHH
GFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQEAERNEAGTDVILHLMDEELE
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHH
YIEPSRIRTLITKYCDFMPVEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
HCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPL
CCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQTDRRVRSIGNFVAKKVADRLRGLKAEQPLFYAEAWDALAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
VKIGSMEDEKFADQVADLILFGTTALASKETDGGTPDPIPCGEKAFTTLSGYKSRLSTEA
HHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
NNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHDDLRFQRVDAELDD
CCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCCCCCCEEECCCHHHH
TLKEDKPELTDQEGETKSESLRTLMKQSLNNDKVTIQVQALKGDNAPPAMILLPEQMRRM
HHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEECHHHHHHH
NDIGALMDQRLPGLPEHHVLLVNRRHPLVEGLLKLKSGSVLVSTSGVSPTESLAQGLARH
HHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
LYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF
HHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TVLEEGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGVDAISKRRMAAIAGDCTEAEE
CCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC
GVIDIKIDREAKTLTISDNGIGMTTDEVKKYINQVAFSSAEDFLEKYKQESDGIIGHFGL
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEHHH
GFYSSFMVSKHVELVTKSACSESKAIRWSCDGSPRFNIQEAERNEAGTDVILHLMDEELE
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHHH
YIEPSRIRTLITKYCDFMPVEVKLEGESINKRNPLWRRNPREITDQEYIELYNYLYPFQG
HCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPRIGGRADWEKGEIKLYCNQVFVSDSIKEVVPHYLLPL
CCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQTDRRVRSIGNFVAKKVADRLRGLKAEQPLFYAEAWDALAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
VKIGSMEDEKFADQVADLILFGTTALASKETDGGTPDPIPCGEKAFTTLSGYKSRLSTEA
HHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
NNRILYCTDEVAQASALSLWTSQGAEILKTETFIDSQFLPWLEARHDDLRFQRVDAELDD
CCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCCCCCCEEECCCHHHH
TLKEDKPELTDQEGETKSESLRTLMKQSLNNDKVTIQVQALKGDNAPPAMILLPEQMRRM
HHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEECHHHHHHH
NDIGALMDQRLPGLPEHHVLLVNRRHPLVEGLLKLKSGSVLVSTSGVSPTESLAQGLARH
HHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
LYDMARLGVGGLEPNELAGFQSRSAVLMGQLMDRAF
HHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]