| Definition | Prochlorococcus marinus str. MIT 9313 chromosome, complete genome. |
|---|---|
| Accession | NC_005071 |
| Length | 2,410,873 |
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The map label for this gene is glmU
Identifier: 33862673
GI number: 33862673
Start: 449558
End: 450898
Strand: Direct
Name: glmU
Synonym: PMT0400
Alternate gene names: 33862673
Gene position: 449558-450898 (Clockwise)
Preceding gene: 33862672
Following gene: 33862680
Centisome position: 18.65
GC content: 52.5
Gene sequence:
>1341_bases ATGCTTGCCGTCGCCATCTTGGCTGCTGGGAAGGGCACCCGCATGAAGAGCTGCCTGCCGAAAGTCTTGCAACCGCTCGC AGGTTCCACATTGGTTGAGCGGGTGTTGACCAGTTGCTCGGGCCTTCAACCTCAACGGCGCTTGTTGATTGTTGGCCACC AGGCGCAAGAGGTGCAACAGCAGCTCACTGATTGGCAAGGCTTGGAGTTTGTTGTTCAACAACCTCAGAACGGCACAGGT CATGCGGTGCAGCAAGTACTGCCCGTATTGGAGGGCTTTGATGGCGAGCTCTTGGTTCTCAATGGCGATGTCCCATTACT TCGACCAAGCACGATCGAACACTTGGTGAACGAACATCGCTCAAGTGGTGCCGACGTCACGCTGCTAACAGCCCGACTCG CAGATCCCACGGGCTATGGCAGGGTGTTTTCAGATCAACAAGGCCGCGTAAGCAGCATCGTTGAACATCGCGACTGTAGT GACGAACAGCGCCACAACAATCTCACTAACGCAGGCATCTACTGCTTCAATTGGAAGAAATTGGCCGCAGTGCTACCCCA ACTTTGTAGTGATAATGATCAAGGTGAGCTCTACCTCACCGACACTGTGGCCTTGCTACCTATTGCGATGCATGTAGAGG TGGCTGATCCCGATGAGGTGAATGGCATCAACGATCGTTGTCAACTTGCCAACTGTGAGGCGCTGCTTCAAGAACGGCTA CGTAACTATTGGATGAAGGAAGGGGTCACTTTTACTGACCCTGCTAGCTGCACGCTTAGTGAAGACTGTCAGTTCGGTAG AGATGTGGTAATTGAACCCCAAACCCATTTGCGGGGCTGCTGCAATATTGGCGATGGCTGCCAGCTTGGCCCAGGAAGCT TGATTGAGAATGCCGAACTTGGCCATGGAGTCAGCGTTCTTCATTCCGTTGTATGTGATGCCAAAGTGGGAAATGAGGTG GCTATTGGCCCTTTCTCACACCTACGCCCTGGAGCAGGCATCGCTGATCAATGCCGTATCGGCAACTTTGTGGAGATTAA AAAAAGCCAAATTGGCGAGGGTTCAAAGGTGAATCACCTCAGTTATATCGGTGACGCACAACTTGGTCGCCATGTCAATG TCGGGGCCGGTACGATCACTGCAAATTACGACGGTGTGAGAAAACATCTCACCGTGGTTGGTGATAACAGCAAAACAGGG GCGAATTCCGTTTTGGTGGCGCCGATTGTTTTAGGGTCGGACGTGACAGTAGGAGCTGGCTCCACTCTCACTAAAGATGT TCCCAATGGTGCTCTCGCCCTTGGCCGCTCCAAACAACTGATTAAAAATGGTTGGCAGTGA
Upstream 100 bases:
>100_bases TCATCACCGCTAGAAGCTGAGCTGATCCTGCTTAAATGCTGTTAACTGCAGTGAAGTTGTCGGAATTCAATTAGATTCCG GCCGATTCGCCATTCGCTCC
Downstream 100 bases:
>100_bases AACGAGAGGATTAAGGCTTAGCCCTCTTAGAGCAATGGGATCAATTTCTCTAGAGCGACACCACGACTAGCCTTAAGCAG AACCACATCGCCGGCCTCAA
Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase
Products: NA
Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase
Number of amino acids: Translated: 446; Mature: 446
Protein sequence:
>446_residues MLAVAILAAGKGTRMKSCLPKVLQPLAGSTLVERVLTSCSGLQPQRRLLIVGHQAQEVQQQLTDWQGLEFVVQQPQNGTG HAVQQVLPVLEGFDGELLVLNGDVPLLRPSTIEHLVNEHRSSGADVTLLTARLADPTGYGRVFSDQQGRVSSIVEHRDCS DEQRHNNLTNAGIYCFNWKKLAAVLPQLCSDNDQGELYLTDTVALLPIAMHVEVADPDEVNGINDRCQLANCEALLQERL RNYWMKEGVTFTDPASCTLSEDCQFGRDVVIEPQTHLRGCCNIGDGCQLGPGSLIENAELGHGVSVLHSVVCDAKVGNEV AIGPFSHLRPGAGIADQCRIGNFVEIKKSQIGEGSKVNHLSYIGDAQLGRHVNVGAGTITANYDGVRKHLTVVGDNSKTG ANSVLVAPIVLGSDVTVGAGSTLTKDVPNGALALGRSKQLIKNGWQ
Sequences:
>Translated_446_residues MLAVAILAAGKGTRMKSCLPKVLQPLAGSTLVERVLTSCSGLQPQRRLLIVGHQAQEVQQQLTDWQGLEFVVQQPQNGTG HAVQQVLPVLEGFDGELLVLNGDVPLLRPSTIEHLVNEHRSSGADVTLLTARLADPTGYGRVFSDQQGRVSSIVEHRDCS DEQRHNNLTNAGIYCFNWKKLAAVLPQLCSDNDQGELYLTDTVALLPIAMHVEVADPDEVNGINDRCQLANCEALLQERL RNYWMKEGVTFTDPASCTLSEDCQFGRDVVIEPQTHLRGCCNIGDGCQLGPGSLIENAELGHGVSVLHSVVCDAKVGNEV AIGPFSHLRPGAGIADQCRIGNFVEIKKSQIGEGSKVNHLSYIGDAQLGRHVNVGAGTITANYDGVRKHLTVVGDNSKTG ANSVLVAPIVLGSDVTVGAGSTLTKDVPNGALALGRSKQLIKNGWQ >Mature_446_residues MLAVAILAAGKGTRMKSCLPKVLQPLAGSTLVERVLTSCSGLQPQRRLLIVGHQAQEVQQQLTDWQGLEFVVQQPQNGTG HAVQQVLPVLEGFDGELLVLNGDVPLLRPSTIEHLVNEHRSSGADVTLLTARLADPTGYGRVFSDQQGRVSSIVEHRDCS DEQRHNNLTNAGIYCFNWKKLAAVLPQLCSDNDQGELYLTDTVALLPIAMHVEVADPDEVNGINDRCQLANCEALLQERL RNYWMKEGVTFTDPASCTLSEDCQFGRDVVIEPQTHLRGCCNIGDGCQLGPGSLIENAELGHGVSVLHSVVCDAKVGNEV AIGPFSHLRPGAGIADQCRIGNFVEIKKSQIGEGSKVNHLSYIGDAQLGRHVNVGAGTITANYDGVRKHLTVVGDNSKTG ANSVLVAPIVLGSDVTVGAGSTLTKDVPNGALALGRSKQLIKNGWQ
Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc
COG id: COG1207
COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
Gene ontology:
Cell location: Cytoplasm
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family
Homologues:
Organism=Escherichia coli, GI1790168, Length=452, Percent_Identity=40.929203539823, Blast_Score=328, Evalue=6e-91,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): GLMU_PROMM (Q7V8F2)
Other databases:
- EMBL: BX548175 - RefSeq: NP_894233.1 - ProteinModelPortal: Q7V8F2 - STRING: Q7V8F2 - GeneID: 1729380 - GenomeReviews: BX548175_GR - KEGG: pmt:PMT0400 - NMPDR: fig|74547.1.peg.400 - eggNOG: COG1207 - HOGENOM: HBG688195 - OMA: GSKVNHL - ProtClustDB: PRK14360 - BioCyc: PMAR74547:PMT0400-MONOMER - GO: GO:0005737 - HAMAP: MF_01631 - InterPro: IPR005882 - InterPro: IPR005835 - InterPro: IPR011004 - TIGRFAMs: TIGR01173
Pfam domain/function: PF00483 NTP_transferase; SSF51161 Trimer_LpxA_like
EC number: =2.7.7.23; =2.3.1.157
Molecular weight: Translated: 47745; Mature: 47745
Theoretical pI: Translated: 6.01; Mature: 6.01
Prosite motif: PS00101 HEXAPEP_TRANSFERASES
Important sites: ACT_SITE 359-359 BINDING 73-73 BINDING 140-140 BINDING 155-155 BINDING 170-170 BINDING 383-383 BINDING 419-419 BINDING 436-436
Signals:
None
Transmembrane regions:
None
Cys/Met content:
3.1 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 3.1 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLAVAILAAGKGTRMKSCLPKVLQPLAGSTLVERVLTSCSGLQPQRRLLIVGHQAQEVQQ CEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHH QLTDWQGLEFVVQQPQNGTGHAVQQVLPVLEGFDGELLVLNGDVPLLRPSTIEHLVNEHR HHHCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHH SSGADVTLLTARLADPTGYGRVFSDQQGRVSSIVEHRDCSDEQRHNNLTNAGIYCFNWKK CCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCEEEECHHH LAAVLPQLCSDNDQGELYLTDTVALLPIAMHVEVADPDEVNGINDRCQLANCEALLQERL HHHHHHHHHCCCCCCCEEEECHHEEEEEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHH RNYWMKEGVTFTDPASCTLSEDCQFGRDVVIEPQTHLRGCCNIGDGCQLGPGSLIENAEL HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCHHCCCCC GHGVSVLHSVVCDAKVGNEVAIGPFSHLRPGAGIADQCRIGNFVEIKKSQIGEGSKVNHL CCHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCHHCCCCEEEEHHHHCCCCCCCCCE SYIGDAQLGRHVNVGAGTITANYDGVRKHLTVVGDNSKTGANSVLVAPIVLGSDVTVGAG EECCCHHCCCEEECCCCEEEECCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCEEECCC STLTKDVPNGALALGRSKQLIKNGWQ CCHHCCCCCCCEECCCCHHHHHCCCC >Mature Secondary Structure MLAVAILAAGKGTRMKSCLPKVLQPLAGSTLVERVLTSCSGLQPQRRLLIVGHQAQEVQQ CEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHH QLTDWQGLEFVVQQPQNGTGHAVQQVLPVLEGFDGELLVLNGDVPLLRPSTIEHLVNEHR HHHCCCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHH SSGADVTLLTARLADPTGYGRVFSDQQGRVSSIVEHRDCSDEQRHNNLTNAGIYCFNWKK CCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCEEEECHHH LAAVLPQLCSDNDQGELYLTDTVALLPIAMHVEVADPDEVNGINDRCQLANCEALLQERL HHHHHHHHHCCCCCCCEEEECHHEEEEEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHH RNYWMKEGVTFTDPASCTLSEDCQFGRDVVIEPQTHLRGCCNIGDGCQLGPGSLIENAEL HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCHHCCCCC GHGVSVLHSVVCDAKVGNEVAIGPFSHLRPGAGIADQCRIGNFVEIKKSQIGEGSKVNHL CCHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCHHCCCCEEEEHHHHCCCCCCCCCE SYIGDAQLGRHVNVGAGTITANYDGVRKHLTVVGDNSKTGANSVLVAPIVLGSDVTVGAG EECCCHHCCCEEECCCCEEEECCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCEEECCC STLTKDVPNGALALGRSKQLIKNGWQ CCHHCCCCCCCEECCCCHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12917642