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The map label for this gene is nadA

Identifier: 32267338

GI number: 32267338

Start: 1760723

End: 1761736

Strand: Direct

Name: nadA

Synonym: HH1839

Alternate gene names: 32267338

Gene position: 1760723-1761736 (Clockwise)

Preceding gene: 32267337

Following gene: 32267339

Centisome position: 97.86

GC content: 37.38

Gene sequence:

>1014_bases
ATGTCAGCCACACTCACCAATGAAATTAAAGATTTACTCCATAAACTCAATGGGCTTTTGGTAGCACATTATTATCAAAA
AGATGAAATTGTTGCCTTGGCAGATTTATGTGGAGATAGTTTGGAGCTTTCCCGTAAGGCTTCAGCGAGTGAGAAAAATC
TCATTGTATTTTGTGGTGTAGCATTTATGGGACAAAGCGTTAAGGTGCTTGCTCCACAAAAGCGTGTGATTATGCCTCGT
TTAGCGTGTTGTTCTATGGCAAGAATGATAGATAGTGATTATTATGATGAAAGCATTGCTCTTTTGCAATCCTATGGCTT
AAGTAAAGATTCTATCTTTCCTATTACTTATATTAATTCAAATGCTGATGTTAAAGCAAAAGTTGCTCAAATGGGAGGGC
TTGTTTGCACAAGTGCAAATGCTCATAAGATTTTTAATTTTGCAAAGGAGCAGGGCAAAAAGATATTTTTTCTCCCTGAT
AAATGTCTGGGAGAGAATCTCGCTCGTTTAAATAGCAAAAAATCCGCGATATTGGGCACAGATGACAAAGAAAAAGTGCT
TAGCGCTGATGTGATTTGCTATGATGGATTCTGTTCTGTGCATCAGCTTTTCACGCCACAAGATATTACCTTTTATCGTG
AAAAATTTGCAGATATTAAAATTGTCGTGCATCCTGAATGCGACCCGAGTGTCGTAGAACTTGCTGATTTTGTTGGCTCG
ACAAGTCAAATCATTGCTTATGTGCAAAATTTGCCTTTAGAGCAAAAAGTGGCAGTAGGCACAGAATTTAATCTTGTCAA
TCGTTTGCGTCCTAAATATAATGGCAAACAAACAACCTTTGTCCTTAGCTCAAGTAAGCCTCAATGTCCCACAATGAATG
AAACAACTCTTGAAGATGTGCGTGATGTGCTTCTTGCTTTTGAAGATAATAAGCCTATTAATGAAGTGTTTTTGGATAAT
GAGATTCAAAAATGGGCAAAAATCGCCCTTGATAGAATGCTTGAACTCTCTTAA

Upstream 100 bases:

>100_bases
ATGGAGCAGATGATTCCAGATGTGCATATTAATGAAAAAGTTAAATTTGCTCAAGACATAGGCACTCATACATAAAATTA
TATAAATTTAAGGAATAGTT

Downstream 100 bases:

>100_bases
AAGATAAAAGTAATTTTACCTTTTGTAACACTTTCTTAAATTTACAAAAAAAAAAAAACGCTATTTAAGTTATAAGATTA
AAAAAATTTTTTAGAATTTA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSATLTNEIKDLLHKLNGLLVAHYYQKDEIVALADLCGDSLELSRKASASEKNLIVFCGVAFMGQSVKVLAPQKRVIMPR
LACCSMARMIDSDYYDESIALLQSYGLSKDSIFPITYINSNADVKAKVAQMGGLVCTSANAHKIFNFAKEQGKKIFFLPD
KCLGENLARLNSKKSAILGTDDKEKVLSADVICYDGFCSVHQLFTPQDITFYREKFADIKIVVHPECDPSVVELADFVGS
TSQIIAYVQNLPLEQKVAVGTEFNLVNRLRPKYNGKQTTFVLSSSKPQCPTMNETTLEDVRDVLLAFEDNKPINEVFLDN
EIQKWAKIALDRMLELS

Sequences:

>Translated_337_residues
MSATLTNEIKDLLHKLNGLLVAHYYQKDEIVALADLCGDSLELSRKASASEKNLIVFCGVAFMGQSVKVLAPQKRVIMPR
LACCSMARMIDSDYYDESIALLQSYGLSKDSIFPITYINSNADVKAKVAQMGGLVCTSANAHKIFNFAKEQGKKIFFLPD
KCLGENLARLNSKKSAILGTDDKEKVLSADVICYDGFCSVHQLFTPQDITFYREKFADIKIVVHPECDPSVVELADFVGS
TSQIIAYVQNLPLEQKVAVGTEFNLVNRLRPKYNGKQTTFVLSSSKPQCPTMNETTLEDVRDVLLAFEDNKPINEVFLDN
EIQKWAKIALDRMLELS
>Mature_336_residues
SATLTNEIKDLLHKLNGLLVAHYYQKDEIVALADLCGDSLELSRKASASEKNLIVFCGVAFMGQSVKVLAPQKRVIMPRL
ACCSMARMIDSDYYDESIALLQSYGLSKDSIFPITYINSNADVKAKVAQMGGLVCTSANAHKIFNFAKEQGKKIFFLPDK
CLGENLARLNSKKSAILGTDDKEKVLSADVICYDGFCSVHQLFTPQDITFYREKFADIKIVVHPECDPSVVELADFVGST
SQIIAYVQNLPLEQKVAVGTEFNLVNRLRPKYNGKQTTFVLSSSKPQCPTMNETTLEDVRDVLLAFEDNKPINEVFLDNE
IQKWAKIALDRMLELS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=343, Percent_Identity=29.4460641399417, Blast_Score=148, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37559; Mature: 37428

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATLTNEIKDLLHKLNGLLVAHYYQKDEIVALADLCGDSLELSRKASASEKNLIVFCGV
CCCCHHHHHHHHHHHHCCEEEEEEECCCCEEEEHHHCCCCHHHHHHCCCCCCCEEEEEEH
AFMGQSVKVLAPQKRVIMPRLACCSMARMIDSDYYDESIALLQSYGLSKDSIFPITYINS
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECC
NADVKAKVAQMGGLVCTSANAHKIFNFAKEQGKKIFFLPDKCLGENLARLNSKKSAILGT
CCCHHHHHHHHCCEEEECCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCCEEECC
DDKEKVLSADVICYDGFCSVHQLFTPQDITFYREKFADIKIVVHPECDPSVVELADFVGS
CCHHHHHHHCEEEECCCHHHHHHCCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCC
TSQIIAYVQNLPLEQKVAVGTEFNLVNRLRPKYNGKQTTFVLSSSKPQCPTMNETTLEDV
HHHHHHHHHCCCCCHHEECCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHH
RDVLLAFEDNKPINEVFLDNEIQKWAKIALDRMLELS
HHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SATLTNEIKDLLHKLNGLLVAHYYQKDEIVALADLCGDSLELSRKASASEKNLIVFCGV
CCCHHHHHHHHHHHHCCEEEEEEECCCCEEEEHHHCCCCHHHHHHCCCCCCCEEEEEEH
AFMGQSVKVLAPQKRVIMPRLACCSMARMIDSDYYDESIALLQSYGLSKDSIFPITYINS
HHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECC
NADVKAKVAQMGGLVCTSANAHKIFNFAKEQGKKIFFLPDKCLGENLARLNSKKSAILGT
CCCHHHHHHHHCCEEEECCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCCEEECC
DDKEKVLSADVICYDGFCSVHQLFTPQDITFYREKFADIKIVVHPECDPSVVELADFVGS
CCHHHHHHHCEEEECCCHHHHHHCCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCC
TSQIIAYVQNLPLEQKVAVGTEFNLVNRLRPKYNGKQTTFVLSSSKPQCPTMNETTLEDV
HHHHHHHHHCCCCCHHEECCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHH
RDVLLAFEDNKPINEVFLDNEIQKWAKIALDRMLELS
HHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA