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The map label for this gene is yfdZ [H]

Identifier: 32267248

GI number: 32267248

Start: 1674507

End: 1675715

Strand: Direct

Name: yfdZ [H]

Synonym: HH1749

Alternate gene names: 32267248

Gene position: 1674507-1675715 (Clockwise)

Preceding gene: 32267247

Following gene: 32267249

Centisome position: 93.07

GC content: 37.39

Gene sequence:

>1209_bases
ATGTTTGATGAAATTGAGTTTGATAAAATAAAACGTTTGCCAAAGTATGTTTTTGCTGCTATTAATGAGATTAAGCTAGA
AATGCGGCGCAATAATGAAGATGTGATTGATTTTTCTATGGGTAATCCTGATGGAGCAACGCCAGAGCATATTATTCAAA
AGCTTTGTGAAGCTGCACAAAAGGGTAAAAATCAAGGATATTCTGTGAGTCGTGGCATTTATAAATTGCGTTTGGCGATT
TGTAATTGGTATAAGCGCACTTATGGAGTGGAGCTAGACCCAGAGAGTGAAGCGTGTGTAACAATGGGAAGCAAAGAGGG
TTATGTGCATCTTGTTCAAGCTATTGCAAATCCCGGTGATAATGCAATCGTAGCTGAACCAGCCTATCCTATACATTATT
ATGCTTTTATTCTTAATGGTGCGAATGTTTCTACTTTTGGTTTAAAGTGGAATGAGCAAATGGAGCTTGATGTAGAGGAT
TTTTTTATCAACATTAAACGCGTATTGAAAGAAGTGATGCCGCGTCCGAAATTTGTTGTAGTTAATTTTCCTCATAATCC
TACAACTATTGTTGTATATAGGGAGTTTTATGAGCGTTTAGTCGCTTTTGCCAAGCAGGAGAGATTCTATATTATTTCTG
ATATTGCTTATGCAGAGCTCTGTTTTGATGGCTTTAAAACGCCAAGTATCCTTGAAATAGAGGGTGCTAAAGATGTAGCG
GTGGAGAGTTATACATTAAGCAAAACCTATAATATGGCAGGTTGGCGTGTAGGCTTTGTAGTAGGAAATAAAAAAATTAT
CCAAGCCTTGCAAAAAATTAAAAGTTGGATTGATTATGGTATCTACACGCCTTTGCAAATTGCCGCTACTATTGCACTTG
AGGGCGACCAATCTTGCGTAAAAGACATCAAAAATACATATGAAAAGCGTATGGAAATATTGATTAAAAGCTTTGGCGAA
GCAGGTTGGGAGATGAAAAAGCCTAAAGCAAGTATGTTTATTTGGGCAAAATTACCTGAATGTGTAGGAGATATGGGAAG
TTTGGAGTTCTCAAAAAGATTGCTTAAAGAGGCAAAAATTGCAGTAAGTCCGGGTGTGGGTTTTGGTGATTATGGTGAGG
GCTATGTGAGGATCGCACTGATTGAAAATGAAAAACGCATTCGCCAAGCTGCACGGAATCTCAAATCATTTCTTAAACAA
TTTCAATAA

Upstream 100 bases:

>100_bases
TAATGATTACAGATTATGATAGTTCGGAAAGTCTTAAGGGTGGTATTTCTGTGAATCTCCGATAGAATCTAAATATCTAA
AACAATACAGAGGAGAAAAT

Downstream 100 bases:

>100_bases
GAGGTTTGTATGTCAAAACTTGTAGTGGGTATGGTTGGCTTTGGTGTTGTAGGAAGTAGCGTATTAAAGGCACTTTTGGC
AAATCGGAATATTATTAGCG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MFDEIEFDKIKRLPKYVFAAINEIKLEMRRNNEDVIDFSMGNPDGATPEHIIQKLCEAAQKGKNQGYSVSRGIYKLRLAI
CNWYKRTYGVELDPESEACVTMGSKEGYVHLVQAIANPGDNAIVAEPAYPIHYYAFILNGANVSTFGLKWNEQMELDVED
FFINIKRVLKEVMPRPKFVVVNFPHNPTTIVVYREFYERLVAFAKQERFYIISDIAYAELCFDGFKTPSILEIEGAKDVA
VESYTLSKTYNMAGWRVGFVVGNKKIIQALQKIKSWIDYGIYTPLQIAATIALEGDQSCVKDIKNTYEKRMEILIKSFGE
AGWEMKKPKASMFIWAKLPECVGDMGSLEFSKRLLKEAKIAVSPGVGFGDYGEGYVRIALIENEKRIRQAARNLKSFLKQ
FQ

Sequences:

>Translated_402_residues
MFDEIEFDKIKRLPKYVFAAINEIKLEMRRNNEDVIDFSMGNPDGATPEHIIQKLCEAAQKGKNQGYSVSRGIYKLRLAI
CNWYKRTYGVELDPESEACVTMGSKEGYVHLVQAIANPGDNAIVAEPAYPIHYYAFILNGANVSTFGLKWNEQMELDVED
FFINIKRVLKEVMPRPKFVVVNFPHNPTTIVVYREFYERLVAFAKQERFYIISDIAYAELCFDGFKTPSILEIEGAKDVA
VESYTLSKTYNMAGWRVGFVVGNKKIIQALQKIKSWIDYGIYTPLQIAATIALEGDQSCVKDIKNTYEKRMEILIKSFGE
AGWEMKKPKASMFIWAKLPECVGDMGSLEFSKRLLKEAKIAVSPGVGFGDYGEGYVRIALIENEKRIRQAARNLKSFLKQ
FQ
>Mature_402_residues
MFDEIEFDKIKRLPKYVFAAINEIKLEMRRNNEDVIDFSMGNPDGATPEHIIQKLCEAAQKGKNQGYSVSRGIYKLRLAI
CNWYKRTYGVELDPESEACVTMGSKEGYVHLVQAIANPGDNAIVAEPAYPIHYYAFILNGANVSTFGLKWNEQMELDVED
FFINIKRVLKEVMPRPKFVVVNFPHNPTTIVVYREFYERLVAFAKQERFYIISDIAYAELCFDGFKTPSILEIEGAKDVA
VESYTLSKTYNMAGWRVGFVVGNKKIIQALQKIKSWIDYGIYTPLQIAATIALEGDQSCVKDIKNTYEKRMEILIKSFGE
AGWEMKKPKASMFIWAKLPECVGDMGSLEFSKRLLKEAKIAVSPGVGFGDYGEGYVRIALIENEKRIRQAARNLKSFLKQ
FQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=22.1662468513854, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=22.1662468513854, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI95147551, Length=394, Percent_Identity=21.3197969543147, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI169881279, Length=394, Percent_Identity=21.3197969543147, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4507369, Length=392, Percent_Identity=22.1938775510204, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=53.7878787878788, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1786816, Length=395, Percent_Identity=24.0506329113924, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788627, Length=319, Percent_Identity=26.9592476489028, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=23.2142857142857, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=23.2142857142857, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=392, Percent_Identity=22.4489795918367, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=23.936170212766, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=24.6786632390745, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=24.2253521126761, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28573069, Length=417, Percent_Identity=23.7410071942446, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646114, Length=417, Percent_Identity=23.7410071942446, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573067, Length=417, Percent_Identity=23.7410071942446, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573065, Length=417, Percent_Identity=23.7410071942446, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 45866; Mature: 45866

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDEIEFDKIKRLPKYVFAAINEIKLEMRRNNEDVIDFSMGNPDGATPEHIIQKLCEAAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
KGKNQGYSVSRGIYKLRLAICNWYKRTYGVELDPESEACVTMGSKEGYVHLVQAIANPGD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCHHHHHHHHCCCCC
NAIVAEPAYPIHYYAFILNGANVSTFGLKWNEQMELDVEDFFINIKRVLKEVMPRPKFVV
CCEEECCCCCEEEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
VNFPHNPTTIVVYREFYERLVAFAKQERFYIISDIAYAELCFDGFKTPSILEIEGAKDVA
EECCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEE
VESYTLSKTYNMAGWRVGFVVGNKKIIQALQKIKSWIDYGIYTPLQIAATIALEGDQSCV
EEEEEECCEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCHHHH
KDIKNTYEKRMEILIKSFGEAGWEMKKPKASMFIWAKLPECVGDMGSLEFSKRLLKEAKI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHCCCCCHHHHHHHHHHHHE
AVSPGVGFGDYGEGYVRIALIENEKRIRQAARNLKSFLKQFQ
EECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFDEIEFDKIKRLPKYVFAAINEIKLEMRRNNEDVIDFSMGNPDGATPEHIIQKLCEAAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
KGKNQGYSVSRGIYKLRLAICNWYKRTYGVELDPESEACVTMGSKEGYVHLVQAIANPGD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCHHHHHHHHCCCCC
NAIVAEPAYPIHYYAFILNGANVSTFGLKWNEQMELDVEDFFINIKRVLKEVMPRPKFVV
CCEEECCCCCEEEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
VNFPHNPTTIVVYREFYERLVAFAKQERFYIISDIAYAELCFDGFKTPSILEIEGAKDVA
EECCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEE
VESYTLSKTYNMAGWRVGFVVGNKKIIQALQKIKSWIDYGIYTPLQIAATIALEGDQSCV
EEEEEECCEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCHHHH
KDIKNTYEKRMEILIKSFGEAGWEMKKPKASMFIWAKLPECVGDMGSLEFSKRLLKEAKI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHCCCCCHHHHHHHHHHHHE
AVSPGVGFGDYGEGYVRIALIENEKRIRQAARNLKSFLKQFQ
EECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]