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The map label for this gene is pgsA

Identifier: 32267179

GI number: 32267179

Start: 1607380

End: 1607925

Strand: Direct

Name: pgsA

Synonym: HH1680

Alternate gene names: 32267179

Gene position: 1607380-1607925 (Clockwise)

Preceding gene: 32267176

Following gene: 32267180

Centisome position: 89.34

GC content: 36.45

Gene sequence:

>546_bases
GTGAAGCATTTACCTAATTTTTTAAGTATTTCACGGATATTTTTAGCAGTTTTATTGCTTTTTGTGGCATTACATTATGA
TGCAGTATTTCCTGATTATATTGATAAGAGTTGGGTAAATTACCTCACTTGCTTTATTTTTTGTATAGCTTCGATCACAG
ATTTTTTTGATGGTTATATTGCGCGTGAATATTGTGTGCATTCACGATTCGGGGAAGTATTTGACCCATTAGCAGATAAA
ATGTTGATTCTATCTGCTTTTATCGCACTTTTGATTTTAGATAGGGCATCTCCTTGGGCGGTATTTTTGATTTTATCGCG
AGAATTTTTTATTACTGGATTGCGCGTAATGGTGGCAGGAAGTGGGGCAAGTGTGGCAGCAAGTAGAAGTGGCAAATATA
AAACAGGTGCACAAATTACTGCAATCGCATTTTTATTGGCAGATTTTTTCCCCGGCGGTGAGATATTACTATGGATTGCA
GTAGCGCTTACTCTTTATTCTGGGGCGGACTATACTCTAAAATATGTTAAAAGTTTGAGCGTATGA

Upstream 100 bases:

>100_bases
ACTAGTATAACTTTTGATACTTTTGTGTTAAGTTAAATAATCCATTGTAGAATCTACTTTAATTTTCAATTTATATAGGC
ATTATTTATAAGGAACAATA

Downstream 100 bases:

>100_bases
GTATTTTTATTGCCCTTATCATCTTATCTTTTTTGGTATTTTTTCACGAATTAGGACATTTTTTTGTGGCTCGTCTATGC
GGTGTGAGAGTAGAAGTATT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKHLPNFLSISRIFLAVLLLFVALHYDAVFPDYIDKSWVNYLTCFIFCIASITDFFDGYIAREYCVHSRFGEVFDPLADK
MLILSAFIALLILDRASPWAVFLILSREFFITGLRVMVAGSGASVAASRSGKYKTGAQITAIAFLLADFFPGGEILLWIA
VALTLYSGADYTLKYVKSLSV

Sequences:

>Translated_181_residues
MKHLPNFLSISRIFLAVLLLFVALHYDAVFPDYIDKSWVNYLTCFIFCIASITDFFDGYIAREYCVHSRFGEVFDPLADK
MLILSAFIALLILDRASPWAVFLILSREFFITGLRVMVAGSGASVAASRSGKYKTGAQITAIAFLLADFFPGGEILLWIA
VALTLYSGADYTLKYVKSLSV
>Mature_181_residues
MKHLPNFLSISRIFLAVLLLFVALHYDAVFPDYIDKSWVNYLTCFIFCIASITDFFDGYIAREYCVHSRFGEVFDPLADK
MLILSAFIALLILDRASPWAVFLILSREFFITGLRVMVAGSGASVAASRSGKYKTGAQITAIAFLLADFFPGGEILLWIA
VALTLYSGADYTLKYVKSLSV

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=181, Percent_Identity=34.8066298342541, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20167; Mature: 20167

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLPNFLSISRIFLAVLLLFVALHYDAVFPDYIDKSWVNYLTCFIFCIASITDFFDGYI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREYCVHSRFGEVFDPLADKMLILSAFIALLILDRASPWAVFLILSREFFITGLRVMVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEC
SGASVAASRSGKYKTGAQITAIAFLLADFFPGGEILLWIAVALTLYSGADYTLKYVKSLS
CCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHC
V
C
>Mature Secondary Structure
MKHLPNFLSISRIFLAVLLLFVALHYDAVFPDYIDKSWVNYLTCFIFCIASITDFFDGYI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREYCVHSRFGEVFDPLADKMLILSAFIALLILDRASPWAVFLILSREFFITGLRVMVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEC
SGASVAASRSGKYKTGAQITAIAFLLADFFPGGEILLWIAVALTLYSGADYTLKYVKSLS
CCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA